Citation Impact
Citing Papers
The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target
2007
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Multicolor Super-Resolution Imaging with Photo-Switchable Fluorescent Probes
2007 StandoutScience
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target.
2007
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations
2008
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding
1998
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
Hepatitis C Virus and eliminating post-transfusion hepatitis
2000 StandoutNobel
ATP Binding Modulates the Nucleic Acid Affinity of Hepatitis C Virus Helicase
2003
The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently
2004
Development of novel therapies for hepatitis C
2010
The Helicase from Hepatitis C Virus Is Active as an Oligomer
1999
Mechanism of autoproteolysis at the NS2–NS3 junction of the hepatitis C virus polyprotein
1998
RecA-like motor ATPases—lessons from structures
2004
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
Quaternary Polymorphism of Replicative Helicase G40P: Structural Mapping and Domain Rearrangement
2006
euHCVdb: the European hepatitis C virus database
2006 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action
2003
Molecular virology of hepatitis C virus.
1997
RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
2006 Nature
Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease–helicase
1999
Asymmetry in the Assembly of the RNAi Enzyme Complex
2003 Standout
Product Release Is the Major Contributor tok cat for the Hepatitis C Virus Helicase-catalyzed Strand Separation of Short Duplex DNA
1998
Complementation of reduced survival, hypotension, and renal abnormalities in angiotensinogen-deficient mice by the human renin and human angiotensinogen genes.
1997 StandoutNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Mechanistic Basis of 5′-3′ Translocation in SF1B Helicases
2009
Internal Processing of Hepatitis C Virus NS3 Protein
1999
Preparation of novel alkylated arginine derivatives suitable for click-cycloaddition chemistry and their incorporation into pseudosubstrate- and bisubstrate-based kinase inhibitors
2010
The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
2002
The 100-kDa U5 snRNP protein (hPrp28p) contacts the 5′ splice site through its ATPase site
2001
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Escherichia coli DNA Helicase II Is Active as a Monomer
1999
DEAD-box proteins: the driving forces behind RNA metabolism
2004
The Serine Protease Domain of Hepatitis C Viral NS3 Activates RNA Helicase Activity by Promoting the Binding of RNA Substrate
2007
NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer
1999
RNA helicases — one fold for many functions
2007
Crystal Structure of the Helicase Domain from the Replicative Helicase-Primase of Bacteriophage T7
1999
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
1999
Hydrophobic Groups Stabilize the Hydration Shell of 2′-O-Methylated RNA Duplexes
2001
A novel recombinant single‐chain hepatitis C virus ns3‐ns4a protein with improved helicase activity
1999
Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV
2010
Crystal Structure of RNA Helicase from Genotype 1b Hepatitis C Virus
1998
Hepatitis C Virus Entry
2007 StandoutNobel
The crystal structure of the Thermus aquaticus DnaB helicase monomer
2007 StandoutNobel
From Structure to Function: New Insights into Hepatitis C Virus RNA Replication
2005
Structural biology of hepatitis C virus
2004
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Overview of Hepatitis C Virus Genome Structure, Polyprotein Processing, and Protein Properties
2000 StandoutNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Homeostasis in Mice with Genetically Decreased Angiotensinogen Is Primarily by an Increased Number of Renin-producing Cells
1999 StandoutNobel
Comparisons between the structures of HCV and Rep helicases reveal structural similarities between SF1 and SF2 super‐families of helicases
1998
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Viral and cellular RNA helicases as antiviral targets
2005
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
Specific telomerase RNA residues distant from the template are essential for telomerase function
1998 StandoutNobel
The case for a common ancestor: kinesin and myosin motor proteins and G proteins.
1998
The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p
1998 StandoutNobel
Crystal Structures of Complexes of PcrA DNA Helicase with a DNA Substrate Indicate an Inchworm Mechanism
1999
Flexibility of the Rings: Structural Asymmetry in the DnaB Hexameric Helicase
2002
Replication of hepatitis C virus
2007 StandoutNobel
Prorenin and Other Large Molecular Weight Forms of Renin*
1980
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Genetic Models of Human Vascular Disease
1995 StandoutNobel
Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line
1999 StandoutScience
Replication of hepatitis C virus
2000
Helicase Inhibitors as Specifically Targeted Antiviral Therapy for Hepatitis c
2009
Mechanism of action of a pestivirus antiviral compound
2000 StandoutNobel
Crystal Structure of the δ′ Subunit of the Clamp-Loader Complex of E. coli DNA Polymerase III
1997
Viral Proteomics
2007
X-Ray Structure of the Pestivirus NS3 Helicase and Its Conformation in Solution
2015
Subcellular Localization, Stability, and trans -Cleavage Competence of the Hepatitis C Virus NS3-NS4A Complex Expressed in Tetracycline-Regulated Cell Lines
2000 StandoutNobel
Structure-Based Mutagenesis Study of Hepatitis C Virus NS3 Helicase
1999
Biochemical and structural analysis of the NS5B RNA‐dependent RNA polymerase of the hepatitis C virus
2000
The Hepatitis C Virus NS3 Proteinase: Structure and Function of a Zinc-Containing Serine Proteinase
1998
Plasma and Renal Prorenin/Renin, Renin mRNA, and Blood Pressure in Dahl Salt-Sensitive and Salt-Resistant Rats
1996
Expression of murine renin genes in subcutaneous connective tissue.
1990
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase
2005
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase
2001 StandoutNobel
Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3′-Terminal Sequences of Viral Positive- and Negative-Strand RNA
2001
Simulations of RNA base pairs in a nanodroplet reveal solvation-dependent stability
2007 StandoutNobel
Assignment of the Multifunctional NS3 Protein of Bovine Viral Diarrhea Virus during RNA Replication: an In Vivo and In Vitro Study
1999
Mutational analysis of the hepatitis C virus RNA helicase
1997
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Characterization of Soluble Hepatitis C Virus RNA-Dependent RNA Polymerase Expressed in Escherichia coli
1999
Increased Inactive Renin in Diabetes Mellitus without Evidence of Nephropathy*
1983
Structure of Hexameric DnaB Helicase and Its Complex with a Domain of DnaG Primase
2007 StandoutScienceNobel
Single‐molecule imaging reveals the translocation and DNA looping dynamics of hepatitis C virus NS3 helicase
2017 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Protein Displacement by DExH/D "RNA Helicases" Without Duplex Unwinding
2004 Science
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus
1998
Cyclosporine-Associated Chronic Nephropathy
1984 Standout
Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase
2001
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Thomas Hesson being referenced
Design, high-level expression, purification and characterization of soluble fragments of the hepatitis C virus NS3 RNA helicase suitable for NMR-based drug discovery methods and mechanistic studies
2001
Structure of the hepatitis C virus RNA helicase domain
1997
Probing the Relationship between RNA-Stimulated ATPase and Helicase Activities of HCV NS3 Using 2‘-O-Methyl RNA Substrates
2000
Immunological evidence that inactive renin is prorenin
1985
Characterization of inactive renin ("prorenin") from renin-secreting tumors of nonrenal origin. Similarity to inactive renin from kidney and normal plasma.
1984
An Inactive, Prorenin-like Substance in Human Kidney and Plasma
1980