Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
RIM1 confers sustained activity and neurotransmitter vesicle anchoring to presynaptic Ca2+ channels
2007
C-terminal domains implicated in the functional surface expression of potassium channels
2003
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
Direct interaction of the calcium sensor protein synaptotagmin I with a cytoplasmic domain of the alpha 1A subunit of the P/Q-type calcium channel
1997
The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2–3
2001
Functional analysis of an archaebacterial voltage-dependent K+ channel
2003 StandoutNatureNobel
Interaction of Cysteine String Proteins with the α1A Subunit of the P/Q-type Calcium Channel
1998
Functional and physical coupling of voltage‐sensitive calcium channels with exocytotic proteins: ramifications for the secretion mechanism
2001
Kvβ1 Subunit Binding Specific for Shaker-Related Potassium Channel α Subunits
1996
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht
1999 Standout
Pathophysiology of migraine aura
2023
Biochemical properties and subcellular distribution of an N-type calcium hannel α1 subunit
1992
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Presynaptic Ca2+ Channels Compete for Channel Type-Preferring Slots in Altered Neurotransmission Arising from Ca2+ Channelopathy
2004
Familial Hemiplegic Migraine and Episodic Ataxia Type-2 Are Caused by Mutations in the Ca2+ Channel Gene CACNL1A4
1996 Standout
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Structure–functional intimacies of transient receptor potential channels
2009
Regulation of the Renal Brush Border Membrane Na+ -H+ Exchanger
1993
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
P-type calcium channels in the somata and dendrites of adult cerebellar purkinje cells
1992
Structural determinants of water permeation through aquaporin-1
2000 StandoutNatureNobel
Reciprocal regulation of P/Q-type Ca2+ channels by SNAP-25, syntaxin and synaptotagmin
1999
Receptor-targeting mechanisms of pain-causing toxins: How ow?
2012 StandoutNobel
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
Calcium control of transmitter release at a cerebellar synapse
1995
Autoinhibitory control of the Ca V 1.2 channel by its proteolytically processed distal C‐terminal domain
2006
Functional impact of syntaxin on gating of N-type and Q-type calcium channels
1995 Nature
Folding membrane proteins in vitro: A table and some comments
2014
Structural determinants of ion selectivity in brain calcium channel
1993
P-type calcium channels in rat central and peripheral neurons
1992
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Characterization of cDNA clones containing CCA trinucleotide repeats derived from human brain
1995
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
DCPIB is a novel selective blocker of ICl,swell and prevents swelling‐induced shortening of guinea‐pig atrial action potential duration
2001
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Differential contribution by conserved glutamate residues to an ion‐selectivity site in the L‐type Ca2+ channel pore
1993
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
1995 StandoutNobel
The concept of a calcium sensor in transmitter release
1999
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Distinctive biophysical and pharmacological properties of class A (BI) calcium channel α1 subunits
1993
Interactions of Presynaptic Ca2+ Channels and Snare Proteins in Neurotransmitter Release
1999
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1998 StandoutNatureNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Participation of multiple calcium channel types in transmission at single climbing fiber to Purkinje cell synapses
1994
X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity
2002 StandoutNatureNobel
International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels
2005 Standout
Calcium channel characteristics conferred on the sodium channel by single mutations
1992 Nature
A recessive C-terminal Jervell and Lange-Nielsen mutation of the KCNQ1 channel impairs subunit assembly
2000
NeuralKCNQ(Kv7) channels
2009
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents
1991 Nature
Different types of calcium channels mediate central synaptic transmission
1993 Nature
Amazing chloride channels: an overview
2003
Molecular genetics of migraine
2009
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Optogenetic Dissection of Entorhinal-Hippocampal Functional Connectivity
2013 StandoutScienceNobel
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Structure and Regulation of Voltage-Gated Ca2+ Channels
2000 Standout
Ablation of P/Q-type Ca 2+ channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the α 1A -subunit
1999
Structure of the Cytoplasmic β Subunit--T1 Assembly of Voltage-Dependent K + Channels
2000 StandoutScienceNobel
The Complex and Intriguing Lives of PIP2 with Ion Channels and Transporters
2001
Altered pain responses in mice lacking α 1E subunit of the voltage-dependent Ca 2+ channel
2000
Upregulation of Dorsal Root Ganglion α2δ Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats
2001
Molecular Structure and Physiological Function of Chloride Channels
2002
Channelrhodopsin-2, a directly light-gated cation-selective membrane channel
2003 Standout
The Structure of the Potassium Channel: Molecular Basis of K + Conduction and Selectivity
1998 StandoutScienceNobel
Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit.
1993
Cyclic Nucleotide-Gated Ion Channels: An Extended Family With Diverse Functions
1996
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
Purification of the N-type calcium channel associated with syntaxin and synaptotagmin. A complex implicated in synaptic vesicle exocytosis.
1994
Molecular cloning of the alpha-1 subunit of an omega-conotoxin-sensitive calcium channel.
1992
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Regional Expression and Cellular Localization of the α1and β Subunit of High Voltage-Activated Calcium Channels in Rat Brain
1997
A Decade of CLC Chloride Channels: Structure, Mechanism, and Many Unsettled Questions
2000
A Functional Connection Between the Pores of Distantly Related Ion Channels as Revealed by Mutant K + Channels
1992 StandoutScienceNobel
Enantioenriched Compounds via Enzyme-Catalyzed Redox Reactions
2011
Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca 2+ and K + channels
1998
Calcium Channel Types with Distinct Presynaptic Localization Couple Differentially to Transmitter Release in Single Calyx-Type Synapses
1999 Nobel
Identification of a syntaxin-binding site on N-Type calcium channels
1994
Identification and differential subcellular localization of the neuronal class C and class D L-type calcium channel alpha 1 subunits.
1993
Chemistry of Inositol Lipid Mediated Cellular Signaling
1995
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Biological and Chemical Applications of Fluorescence Correlation Spectroscopy: A Review
2001
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Revealing the Architecture of a K + Channel Pore Through Mutant Cycles with a Peptide Inhibitor
1995 StandoutScienceNobel
Differential phosphorylation of two size forms of the N-type calcium channel alpha 1 subunit which have different COOH termini.
1994
Different Fast-Gate Regulation by External Cl− and H+ of the Muscle-Type Clc Chloride Channels
2001
Functional disorders of the sympathetic nervous system in mice lacking the α 1B subunit (Ca v 2.2) of N-type calcium channels
2001
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Works of Thomas Friedrich being referenced
Diverse Functional Consequences of Mutations in the Na+/K+-ATPase α2-Subunit Causing Familial Hemiplegic Migraine Type 2
2008
Proteorhodopsin is a Light-driven Proton Pump with Variable Vectoriality
2002
Functional Cell-free Synthesis of a Seven Helix Membrane Protein: In situ Insertion of Bacteriorhodopsin into Liposomes
2007
Rare missense variants inATP1A2 in families with clustering of common forms of migraine
2005
Primary structure and functional expression of the ω-conotoxin-sensitive N-type calcium channel from rabbit brain
1993
Molecular cloning and characterization of a novel calcium channel from rabbit brain
1992
Primary structure and functional expression from complementary DNA of a brain calcium channel
1991 Nature
CLC Chloride Channels in Caenorhabditis elegans
1999
Pathophysiology of KCNQ Channels: Neonatal Epilepsy and Progressive Deafness
2000
Site-specific interaction of thrombin and inhibitors observed by fluorescence correlation spectroscopy
1997
An Internalization Signal in ClC-5, an Endosomal Cl−Channel Mutated in Dent's Disease
2001
Molecular Determinants of KCNQ (Kv7) K+Channel Sensitivity to the Anticonvulsant Retigabine
2005
Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine
2009
The CLC chloride channel family
1999
Mutational Analysis Demonstrates That ClC-4 and ClC-5 Directly Mediate Plasma Membrane Currents
1999
Structural Determinants of M-Type KCNQ (Kv7) K+Channel Assembly
2006
KCNQ4, a Novel Potassium Channel Expressed in Sensory Outer Hair Cells, Is Mutated in Dominant Deafness
1999
Na,K-ATPase mutations in familial hemiplegic migraine lead to functional inactivation
2005
Non‐specific activation of the epithelial sodium channel by the CFTR chloride channel
2001
A carboxy‐terminal domain determines the subunit specificity of KCNQ K + channel assembly
2003
Functional Significance of E2 State Stabilization by Specific α/β-Subunit Interactions of Na,K- and H,K-ATPase
2008
A Kazal-type inhibitor with thrombin specificity from Rhodnius prolixus
1993
Asymmetric Bioreduction of Activated C=C Bonds Using Zymomonas mobilis NCR Enoate Reductase and Old Yellow Enzymes OYE 1–3 from Yeasts
2008
Two heads are better than one: crystal structure of the insect derived double domain Kazal inhibitor rhodniin in complex with thrombin.
1995 Nobel
Identification of the renal Na+/H+ exchanger with N,N′-dicyclohexylcarbodiimide (DCCD) and amiloride analogues
1986
The ornithodorin-thrombin crystal structure, a key to the TAP enigma?
1996 Nobel