Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
2004 StandoutScience
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
The many substrates and functions of ATM
2000
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Role of Jun and Jun kinase in resistance of cancer cells to therapy
2003
Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20
2002
The p53 and Mdm2 families in cancer
2002
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
2001 StandoutNobel
Cell cycle checkpoint signaling through the ATM and ATR kinases
2001 Standout
p53-Mdm2--the affair that never ends
2002
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Cell-cycle checkpoints and cancer
2004 StandoutNature
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis
1999
Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor
2002
Chk2 kinase — a busy messenger
2001
The evolution of diverse biological responses to DNA damage: insights from yeast and p53
2001
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Liver Tumor Development
2003
DNA damage checkpoints in mammals
2005
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
DNA damage, p53, apoptosis and vascular disease
2007
Mdm2-mediated ubiquitylation: p53 and beyond
2009
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Ribosome biogenesis surveillance: probing the ribosomal protein-Mdm2-p53 pathway
2010
MAP kinase signalling pathways in cancer
2007 Standout
Using Mouse Models to Explore MDM-p53 Signaling in Development, Cell Growth, and Tumorigenesis
2012
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
β-Arrestin 2 Functions as a G-Protein-coupled Receptor-activated Regulator of Oncoprotein Mdm2
2003
The p53–Mdm2 module and the ubiquitin system
2002
ATM Mediates Phosphorylation at Multiple p53 Sites, Including Ser46, in Response to Ionizing Radiation
2002
ATM: Genome stability, neuronal development, and cancer cross paths
2001
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
2002
Regulation of the p53 Tumor Suppressor Protein
1999
Recombinational DNA repair and human disease
2002
An E3-like Factor that Promotes SUMO Conjugation to the Yeast Septins
2001
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
NFBD1/KIAA0170 Is a Chromatin-associated Protein Involved in DNA Damage Signaling Pathways
2003
Mammalian MAP kinase signalling cascades
2001 StandoutNature
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
A DNA Damage–Induced p53 Serine 392 Kinase Complex Contains CK2, hSpt16, and SSRP1
2001
Mechanisms of switching on p53: a role for covalent modification?
1999
Exploring complex networks
2001 StandoutNature
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
2005 StandoutNature
Mammalian G1- and S-phase checkpoints in response to DNA damage
2001
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Post-translational modification of p53 in tumorigenesis
2004
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Signalling via the hypoxia-inducible factor-1α requires multiple posttranslational modifications
2004
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
Regulation of JNK signaling by GSTp
1999
Requirement of the MRN complex for ATM activation by DNA damage
2003
ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro
2003
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
2001
The cellular response to p53: the decision between life and death
1999
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Regulation of p53 Function
2001
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems
1999 Nobel
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Mdmx stabilizes p53 and Mdm2 via two distinct mechanisms
2001
Regulation of p53 Function and Stability by Phosphorylation
1999
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
2000
Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
2003
Multiple C-Terminal Lysine Residues Target p53 for Ubiquitin-Proteasome-Mediated Degradation
2000
Two Molecularly Distinct G2/M Checkpoints Are Induced by Ionizing Irradiation
2002
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
Surfing the p53 network
2000 StandoutNature
Regulation of p53 stability
1999
Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.
2000
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Mitochondrial HEP27 Is a c-Myb Target Gene That Inhibits Mdm2 and Stabilizes p53
2010
MEKK1/JNK signaling stabilizes and activates p53
1998
Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM
2004
Human DNA Repair Genes
2001 StandoutScienceNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
c-Abl Regulates p53 Levels under Normal and Stress Conditions by Preventing Its Nuclear Export and Ubiquitination
2001 StandoutNobel
Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinase.
2001
Inhibition of c-Jun N-Terminal Kinase 2 Expression Suppresses Growth and Induces Apoptosis of Human Tumor Cells in a p53-Dependent Manner
2000
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Low levels of glutathione peroxidase 1 activity in selenium-deficient mouse liver affect c-Jun N-terminal kinase activation and p53 phosphorylation on Ser-15 in pro-oxidant-induced aponecrosis
2003
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Loss of Oncogenic H-ras-Induced Cell Cycle Arrest and p38 Mitogen-Activated Protein Kinase Activation by Disruption of Gadd45a
2003
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Thomas Buschmann being referenced
Distinct pattern of p53 phosphorylation in human tumors
2001
ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage
2001
Mdm2 association with p53 targets its ubiquitination
1998
Stabilization and Activation of p53 by the Coactivator Protein TAFII31
2001
Amino-terminal-derived JNK Fragment Alters Expression and Activity of c-Jun, ATF2, and p53 and Increases H2O2-induced Cell Death
2000
The Mdm-2 Amino Terminus Is Required for Mdm2 Binding and SUMO-1 Conjugation by the E2 SUMO-1 Conjugating Enzyme Ubc9
2001
Analysis of JNK, Mdm2 and p14ARF contribution to the regulation of mutant p53 stability
2000
JNK targets p53 ubiquitination and degradation in nonstressed cells
1998
p53 phosphorylation and association with murine double minute 2, c-Jun NH2-terminal kinase, p14ARF, and p300/CBP during the cell cycle and after exposure to ultraviolet irradiation.
2000
Jun NH2-Terminal Kinase Phosphorylation of p53 on Thr-81 Is Important for p53 Stabilization and Transcriptional Activities in Response to Stress
2001