Standout Papers
Citation Impact
Citing Papers
Molecular Architecture of a Eukaryotic Translational Initiation Complex
2013 ScienceNobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Crystal Structure of the Eukaryotic 40 S Ribosomal Subunit in Complex with Initiation Factor 1
2010 Science
The Signal Recognition Particle (SRP) RNA Links Conformational Changes in the SRP to Protein Targeting
2007
Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation
2007
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open
2012 StandoutScienceNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Crystal Structure of the Eukaryotic Ribosome
2010 Science
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
Structures of the Bacterial Ribosome at 3.5 A Resolution
2005 Science
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Accurate computational design of multipass transmembrane proteins
2018 StandoutScienceNobel
Nmd3 is a structural mimic of eIF 5A, and activates the cp GTP ase Lsg1 during 60S ribosome biogenesis
2017 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy
2011 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Reinitiation and Other Unconventional Posttermination Events during Eukaryotic Translation
2013
Preparation of macromolecular complexes for cryo-electron microscopy
2007 StandoutNobel
Unravelling biological macromolecules with cryo-electron microscopy
2016 Nature
High-resolution single-particle orientation refinement based on spectrally self-adapting common lines
2009
Structure of the E. coli signal recognition particle bound to a translating ribosome
2006 Nature
The Structure and Function of the Eukaryotic Ribosome
2012
Comparison of Fungal 80 S Ribosomes by Cryo-EM Reveals Diversity in Structure and Conformation of rRNA Expansion Segments
2007 StandoutNobel
Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel
2012
FREALIGN: High-resolution refinement of single particle structures
2006
SRP-mediated protein targeting: structure and function revisited
2004
Assembly and nuclear export of pre-ribosomal particles in budding yeast
2014
Atomic structures of the eukaryotic ribosome
2012
Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome
2016
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
The TRPC3 Channel Has a Large Internal Chamber Surrounded by Signal Sensing Antennas
2006
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
Composition and Structure of the 80S Ribosome from the Green Alga Chlamydomonas reinhardtii: 80S Ribosomes are Conserved in Plants and Animals
2005
Recognition of a signal peptide by the signal recognition particle
2010 Nature
Mechanism of eIF6 release from the nascent 60S ribosomal subunit
2015
Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor
2010
Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
2013 StandoutNatureNobel
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
Visualization of macromolecular complexes using cryo-electron microscopy with FEI Tecnai transmission electron microscopes
2008 StandoutNobel
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
RNA polymerase II–TFIIB structure and mechanism of transcription initiation
2009 Nature
RNA-mediated interaction between the peptide-binding and GTPase domains of the signal recognition particle
2005 StandoutNobel
Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
2004 StandoutNobel
Structures of the human and Drosophila 80S ribosome
2013 Nature
Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
2013 StandoutNobel
Structure of the SecY Complex Unlocked by a Preprotein Mimic
2012
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
New developments in theATSASprogram package for small-angle scattering data analysis
2012 Standout
Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells
2016
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Single-Particle Cryo-EM at Crystallographic Resolution
2015
Structure of the E. coli protein-conducting channel bound to a translating ribosome
2005 StandoutNatureNobel
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
Conformations of the Signal Recognition Particle Protein Ffh from Escherichia coli as Determined by FRET
2005
Long-Timescale Dynamics and Regulation of Sec-Facilitated Protein Translocation
2012
Reaching the Information Limit in Cryo-EM of Biological Macromolecules: Experimental Aspects
2011
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
Mechanistic insight into eukaryotic 60S ribosomal subunit biogenesis by cryo-electron microscopy
2016
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
SPIDER image processing for single-particle reconstruction of biological macromolecules from electron micrographs
2008 StandoutNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
RF3 Induces Ribosomal Conformational Changes Responsible for Dissociation of Class I Release Factors
2007 StandoutNobel
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Two-step model of stop codon recognition by eukaryotic release factor eRF1
2013
60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle
2014
Orientational Preferences of Neighboring Helices Can Drive ER Insertion of a Marginally Hydrophobic Transmembrane Helix
2012
High-resolution Electron Microscopy of Helical Specimens: A Fresh Look at Tobacco Mosaic Virus
2007
Cryo-EM structures of Arx1 and maturation factors Rei1 and Jjj1 bound to the 60S ribosomal subunit
2012
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Mechanisms of Sec61/SecY-Mediated Protein Translocation Across Membranes
2012
mTORC1 phosphorylates LARP6 to stimulate type I collagen expression
2017
The Role of ABCE1 in Eukaryotic Posttermination Ribosomal Recycling
2010
Yeast Ribosomal Protein L40 Assembles Late into Precursor 60 S Ribosomes and Is Required for Their Cytoplasmic Maturation
2012
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution
2014
Quality control mechanisms during ribosome maturation
2013
Termination and post-termination events in eukaryotic translation
2012
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
Exploring the nature of the translocon-assisted protein insertion
2012 StandoutNobel
A structural model of the active ribosome-bound membrane protein insertase YidC
2014
Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning
2015 StandoutScienceNobel
Signal Recognition Particle Receptor Exposes the Ribosomal Translocon Binding Site
2006 Science
Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
2013
The Structure of the Ribosome with Elongation Factor G Trapped in the Posttranslocational State
2009 StandoutScienceNobel
Identification of cytoplasmic residues of Sec61p involved in ribosome binding and cotranslational translocation
2005
Ribosome Biogenesis in the YeastSaccharomyces cerevisiae
2013
Direct Simulation of Early-Stage Sec-Facilitated Protein Translocation
2012
Structure of Eukaryotic RNA Polymerases
2008
Crystal Structure of the Eukaryotic 60 S Ribosomal Subunit in Complex with Initiation Factor 6
2011 Science
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
Multiple conformational switches in a GTPase complex control co-translational protein targeting
2009
Distinct Mechanisms of Transcription Initiation by RNA Polymerases I and II
2018
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
2010
The Crystal Structure of the Signal Recognition Particle in Complex with Its Receptor
2011 StandoutScienceNobel
Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast
2011
Structural Insights Into the Signal Recognition Particle
2004 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Transient tether between the SRP RNA and SRP receptor ensures efficient cargo delivery during cotranslational protein targeting
2010
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
The Structure of the Eukaryotic Ribosome at 3.0 Å Resolution
2011 Science
Works of Thomas Becker being referenced
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2
2020 Science
Structure of the signal recognition particle interacting with the elongation-arrested ribosome
2004 StandoutNatureNobel
Structure of eEF3 and the mechanism of transfer RNA release from the E-site
2006 Nature
Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome
2015
ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the membrane
2005
Structure of the mammalian oligosaccharyl-transferase complex in the native ER protein translocon
2014
The DARC site: a database of aligned ribosomal complexes
2011
Structures of the Sec61 complex engaged in nascent peptide translocation or membrane insertion
2014 Nature
Following the signal sequence from ribosomal tunnel exit to signal recognition particle
2006 Nature
Structure of a human translation termination complex
2015
Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
2011
Structure of an Archaeal RNA Polymerase
2007
Automatic post-picking using MAPPOS improves particle image detection from cryo-EM micrographs
2013
Structural basis of highly conserved ribosome recycling in eukaryotes and archaea
2012 Nature
Localization and dynamic behavior of ribosomal protein L30e
2005 StandoutNobel
Structure of the no-go mRNA decay complex Dom34–Hbs1 bound to a stalled 80S ribosome
2011
Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide
2010
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution
2010
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel