Standout Papers
- Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells. (1989)
- Mammalian Growth-Associated H1 Histone Kinase: a Homolog of cdc2+/CDC28 Protein Kinases Controlling Mitotic Entry in Yeast and Frog Cells (1989)
- Maturation-promoting factor and the regulation of the cell cycle (1989)
Citation Impact
Citing Papers
The A- and B-type cyclin associated cdc2 kinases in Xenopus turn on and off at different times in the cell cycle.
1990 StandoutNobel
Control of the higher eukaryote cell cycle by p34cdc2 homologues
1989 StandoutNobel
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
An M-phase-specific protein kinase of Xenopus oocytes: Partial purification and possible mechanism of its periodic activation
1988
Neuronal phosphoproteins
1987
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
1990
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Feedback control of mitosis in budding yeast
1991
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
Involvement of p34cdc2 in establishing the dependency of S phase on mitosis
1991 StandoutNatureNobel
Myb DNA binding inhibited by phosphorylation at a site deleted during oncogenic activation
1990 StandoutNatureNobel
In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase
1989
Differential regulation of histone H1 and ribosomal S6 kinases during sea star oocyte maturation
1987 StandoutNobel
Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase
1990 StandoutNatureNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function
1991
Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex
1995 Nature
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
A light-entrainment mechanism for the Drosophila circadian clock
1996 StandoutNatureNobel
Substrates for p34cdc2: In vivo veritas?
1990 StandoutNobel
The Drosophila gene torso encodes a putative receptor tyrosine kinase
1989 StandoutNatureNobel
Microinjection of p34cdc2 kinase induces marked changes in cell shape, cytoskeletal organization, and chromatin structure in mammalian fibroblasts
1990
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
1991
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase
1990
A brain-specific activator of cyclin-dependent kinase 5
1994 StandoutNatureNobel
cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF
1988
Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C
1990
Cyclic activation of histone H1 kinase during sea urchin egg mitotic divisions
1988
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Characterization of maturation-activated histone H1 and ribosomal S6 kinases in sea star oocytes
1987
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
cdc25+ functions as an inducer in the mitotic control of fission yeast
1986 StandoutNobel
Cross-Reactions of Adenosine 3',5'-Monophosphate-dependent Protein Kinase Systems from Rat Liver and Rabbit Skeletal Muscle
1971
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Cell Communication, Calcium Ion, and Cyclic Adenosine Monophosphate
1970 Science
Dominoes and Clocks: the Union of Two Views of the Cell Cycle
1989 Science
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
Separation of regulatory and catalytic subunits of the cyclic 3′, 5′-adenosine monophosphate-dependent protein kinase(s) of rabbit skeletal muscle
1971
The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis
1987 StandoutNobel
The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation
1986 StandoutNobel
Studies on the Adenosine 3′, 5′-Monophosphate-dependent Protein Kinases of Rabbit Skeletal Muscle
1972 StandoutNobel
Histone H1 kinase from mouse plasmacytoma
1984
Biochemical characterization of the p342 protein kinase component of purified maturation-promoting factor from Xenopus eggs
1989
Phosphorylation of Very‐Lysine‐Rich Histone in Physarum polycephalum
1973
Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.
1994 StandoutNobel
CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASES, IV. WIDESPREAD OCCURRENCE OF ADENOSINE 3′,5′-MONOPHOSPHATE-DEPENDENT PROTEIN KINASE IN VARIOUS TISSUES AND PHYLA OF THE ANIMAL KINGDOM
1969
Substrate specificity of the cyclic AMP-dependent protein kinase.
1975
Histone H1 kinase in exponential and synchronous populations of Chinese hamster fibroblasts.
1986
Inactivation of Glycogen Synthetase and Activation of Phosphorylase Kinase by Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases
1970 StandoutNobel
A cyclic AMP-dependent protein kinase from frog bladder epithelial cells
1970
Changes of free calcium levels with stages of the cell division cycle
1985 StandoutNatureNobel
Chromatin higher-order structure studied by neutron scattering and scanning transmission electron microscopy.
1987 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Purification and Characterization of a Specific Histone Hl Protein Kinase from Mouse Plasmacytoma
1981
FURTHER CHARACTERIZATION OF THE F1-HISTONE PHOSPHOKINASE OF METAPHASE-ARRESTED ANIMAL CELLS
1973
Multiple forms of hepatic adenosine 3':5'-monophosphate dependent protein kinase
1971
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.
1989 StandoutNobel
Complete amino acid sequence of the catalytic subunit of bovine cardiac muscle cyclic AMP-dependent protein kinase.
1981 StandoutNobel
Molecular Biology of Learning: Modulation of Transmitter Release
1982 StandoutScienceNobel
MIF2 is required for mitotic spindle integrity during anaphase spindle elongation in Saccharomyces cerevisiae.
1993 StandoutNobel
Control of cell-cycle timing in early embryos of Caenorhabditis elegans
1985
Cyclic Nucleotide-dependent Protein Kinases
1970
A cyclic 3′,5′-AMP-stimulated protein kinase from cardiac muscle
1970 StandoutNobel
An Adenosine 3′,5′-Monophosphate-dependent Protein Kinase from Escherichia coli
1969
[3] Protein kinase phosphorylation site sequences and consensus specificity motifs: Tabulations
1991
Studies on the Role and Mode of Operation of the Very‐Lysine‐Rich Histone H1 in Eukaryote Chromatin
1977
Activation of Protein Kinase by Physiological Concentrations of Cyclic AMP
1974
The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae
1988 StandoutScienceNobel
Amino Acid Sequence and Sequence Variability of the Amino-terminal Regions of Lysine-rich Histones
1971
Non-dependence on native structure of pig liver pyruvate kinase when used as a substrate for cyclic 3′,5′-AMP-stimulated protein kinase
1975
A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate
1970 StandoutNobel
Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases
1971 StandoutNobel
Occurrence and properties of a chromatin-associated Fl-histone phosphokinase in mitotic Chinese hamster cells
1972
The role of cyclin B in meiosis I.
1989
Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.
1989
Phosphorylation of H1 histones
1983
Affinity labeling of the catalytic subunit of cyclic AMP-dependent protein kinase by N alpha-tosyl-L-lysine chloromethyl ketone.
1979
Cyclic AMP Regulation of Eukaryotic Gene Transcription by Two Discrete Molecular Mechanisms
1985 Science
Molecular Forms and Subunit Composition of a Cyclic Adenosine 3′,5′-Monophosphate-dependent Protein Kinase Purified from Bovine Heart Muscle
1972
Identification of a Novel Proline-directed Serine/Threonine Protein Kinase in Rat Pheochromocytoma
1989
Functionally homologous cell cycle control genes in budding and fission yeast
1982 StandoutNatureNobel
A cyclic-3′,5′-adenosine monophosphate dependent protein kinase from the adrenal cortex: Comparison with a cyclic AMP binding protein
1970
Phosphorylation at clustered -Ser-Pro-X-Lys/Arg- motifs in sperm-specific histones H1 and H2B.
1990
Activation of multiple protein kinases during the burst in protein phosphorylation that precedes the first meiotic cell division in Xenopus oocytes.
1988
Phosphorylation of tau protein by purified p34cdc28 and a related protein kinase from neurofilaments.
1992
Magnetic Resonance Studies of Deoxyribonucleoprotein
1973 Nature
Resensitization of the Desensitized Follicular Adenylyl Cyclase System to Luteinizing Hormone*
1979
Role of the Receptor in the Mechanism of Action of Adenosine 3′:5′-Cyclic Monophosphate
1971
Adenosine 3′,5′-Monophosphate-dependent Protein Kinase from Adipose Tissue
1972 StandoutNobel
Chromatin Structure: Oligomers of the Histones
1974 StandoutScienceNobel
ANIMAL CELL CYCLES AND THEIR CONTROL
1992 StandoutNobel
Mechanism of Activation by Adenosine 3′:5′-Cyclic Monophosphate of a Protein Phosphokinase from Rabbit Reticulocytes
1970
Cyclic Nucleotide-dependent Protein Kinases
1969
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
Possible role for cyclic nucleotides and phosphorylated membrane proteins in postsynaptic actions of neurotransmitters†
1976 Nature
Changes in intracellular pH of plasmodium during the cell cycle and in response to starvation
1982
Identification of the Major Phosphorylation Site of the Hepatitis C Virus H Strain NS5A Protein as Serine 2321
1999 StandoutNobel
A mouse temperature-sensitive mutant defective in H1 histone phosphorylation is defective in deoxyribonucleic acid synthesis and chromosome condensation
1981
Structure of nucleosome core particles of chromatin
1977 StandoutNatureNobel
Enthalpy of Hydrolysis of the 3′ Bond of Adenosine 3′, 5′-Monophosphate and Guanosine 3′, 5′-Monophosphate
1969
A MOLECULAR DESCRIPTION OF NERVE TERMINAL FUNCTION
1983
Studies on the Role of Adenosine 3',5'-Monophosphate in the Hepatic Actions of Glucagon and Catecholamines
1971 StandoutNobel
An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase.
1992
Activation and nuclear translocation of protein kinase during transsynaptic induction of tyrosine 3-monooxygenase.
1976
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation
1989 StandoutNobel
Interaction of the Subunits of Adenosine 3′:5′-Cyclic Monophosphate-Dependent Protein Kinase of Muscle
1971
Control of Cell Division by Very Lysine Rich Histone (F1) Phosphorylation
1974 Nature
Histones and Their Modification
1986
Protamine Kinase from Rainbow Trout Testis
1970
Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto-oncogene.
1988
Purification and characterization of catalytic subunit of skeletal muscle adenosine 3':5'-monophosphate-dependent protein kinase.
1977
Interconversion of Cyclic Nucleotide-Activated and Cyclic Nucleotide-Independent Forms of a Protein Kinase from Beef Heart
1971
Interconversion of Phospho- and Dephospho- Forms of Pig Heart Pyruvate Dehydrogenase
1970
PROTEIN SERINE/THREONINE KINASES
1987 StandoutNobel
Synthetic substrate for cyclic AMP-dependent protein kinase
1975 Nature
Physical Studies of Chromatin
1976
Role of the Cyclic AMP—Dependent Protein Kinase in Signal Transduction
1989 StandoutNobel
Nuclear protein kinases
1984
Catalysis of the Phosphorylase Kinase Activation Reaction
1971 StandoutNobel
Cell‐Cycle Dependence of Two Nuclear Histone Kinase Enzyme Activities
1976
Isolation and analysis of a mammalian temperature-sensitive mutant defective in G2 functions
1986
Evidence for the involvement of H1 histone phosphorylation in chromosome condensation
1980 Nature
The role of protein phosphorylation in neural and hormonal control of cellular activity
1982 Nature
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates.
1991 StandoutNobel
Works of Thomas A. Langan being referenced
Characterization of a Phosphatase Specific for Phosphorylated Histones and Protamine
1969
Action of Adenosine 3',5'-Monophosphate-dependent Histone Kinase in Vivo
1969
Tyrosine hydroxylase: a substrate of cyclic AMP-dependent protein kinase.
1980
Phosphorylation of Lysine-rich Histone in the Isolated Perfused Rat Liver
1973
Purification and characterization of growth-associated H1 histone kinase from Novikoff hepatoma cells.
1990
Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells.
1989 StandoutNobel
Mammalian Growth-Associated H1 Histone Kinase: a Homolog of cdc2+/CDC28 Protein Kinases Controlling Mitotic Entry in Yeast and Frog Cells
1989 StandoutNobel
Molecular basis of control of mitotic cell division in eukaryotes
1974 Nature
Chapter 14. Isolation of Histone Kinases
1978
PHOSPHORYLATION OF LIVER HISTONE FOLLOWING THE ADMINISTRATION OF GLUCAGON AND INSULIN
1969
Complexes of deoxyribonucleic acid with lysine-rich (f1) histone phosphorylated at two separate sites: Circular dichroism studies
1972
Sites in histone H1 selectively phosphorylated by guanosine 3‘:5‘-monophosphate-dependent protein kinase.
1981
Variation in Primary Structure at a Phosphorylation Site in Lysine-rich Histones
1971
CYCLIC AMP AND HISTONE PHOSPHORYLATION*
1971
Chapter 13. Methods for the Assessment of Site-Specific Histone Phosphorylation
1978
Altered conformational effects of phosphorylated lysine-rich histone (f-1) in f-1-deoxyribonucleic acid complexes. Circular dichroism and immunological studies
1971
Advance of mitosis by histone phosphokinase
1976
Histone Phosphorylation: Stimulation by Adenosine 3′,5′-Monophosphate
1968 Science
Characterization of highly phosphorylated subcomponents of rat thymus H1 histone.
1982
Studies on the mechanism of activation of mitotic histone H1 kinase
1980
Phosphorylation of the DNA-binding domain of nonhistone high-mobility group I protein by cdc2 kinase: reduction of binding affinity.
1991
Phosphorylation by cdc2 kinase modulates DNA binding activity of high mobility group I nonhistone chromatin protein.
1991
The structure of chromatin reconstituted with phosphorylated H1. Circular dichroism and thermal denaturation studies.
1984
H1 histone kinases from nuclei of Physarum polycephalum
1983