Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
In situ click chemistry generation of cyclooxygenase-2 inhibitors
2017 Standout
Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?
1994 Standout
2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation
2012
Oxindole synthesis by palladium-catalysed aromatic C–H alkenylation
2010
Effects of the Antifungal Agents on Oxidative Drug Metabolism
2000
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Methods for Predicting Human Drug Metabolism
2006
Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 670 Drug Compounds
2008
Prediction of pharmacokinetic properties using experimental approaches during early drug discovery
2001
Meeting the Challenge of Predicting Hepatic Clearance of Compounds Slowly Metabolized by Cytochrome P450 Using a Novel Hepatocyte Model, HepatoPac
2013
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes
2015
Quantitative structure–pharmacokinetic relationships for drug clearance by using statistical learning methods
2005
Biosynthesis of 15-deoxy-Δ12,14-PGJ2 and the ligation of PPARγ
2003
Quantitative high‐throughput analysis of drugs in biological matrices by mass spectrometry
2003
DrugBank: a knowledgebase for drugs, drug actions and drug targets
2007 Standout
The recent impact of solid-phase synthesis on medicinally relevant benzoannelated nitrogen heterocycles
2002
Use of Cryopreserved Human Hepatocytes in Sandwich Culture to Measure Hepatobiliary Transport
2006
Lung cancer: current therapies and new targeted treatments
2016 Standout
The biology and pharmacology of PGD2
1988
Platelet Activation and Atherothrombosis
2007 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Fluorine in Drug Design: A Case Study with Fluoroanisoles
2015
Identification of 19 (R)-OH prostaglandin E2 as a selective prostanoid EP2-receptor agonist
1993
Quantification of noncyclooxygenase derived prostanoids as a marker of oxidative stress
1991
Microfluidic organs-on-chips
2014 Standout
Measurement of Eicosanoids in Cancer Tissues
2007
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants
2002
Immune Regulation by helminth parasites: cellular and molecular mechanisms
2003 Standout
Prostaglandin and thromboxane biosynthesis
1991
Eicosanoids and cancer
2010 Standout
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
The Role of N-Glycosylation of Human Thromboxane A2Receptor in Ligand Binding
1998
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor γ and promotes adipocyte differentiation
1995 Standout
The role of drug metabolizing enzymes in clearance
2014
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Novel cyclooxygenase‐catalyzed bioactive prostaglandin F2α from physiology to new principles in inflammation
2006
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
Lipid peroxidation: its mechanism, measurement, and significance
1993 Standout
A plastid organelle as a drug target in apicomplexan parasites
1997 StandoutNature
The road map to oral bioavailability: an industrial perspective
2006
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Ontogeny of Hepatic and Renal Systemic Clearance Pathways in Infants
2002
Double-blind comparison of single-dose alatrofloxacin and cefotetan as prophylaxis of infection following elective colorectal surgery
1998
Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.
1990
Chlorhexidine–Alcohol versus Povidone–Iodine for Surgical-Site Antisepsis
2010 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes
2006 Standout
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Orally Absorbed Cyclic Peptides
2017
Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed Biomolecules Synthesis
2008 Standout
Solid-Phase Intramolecular N-Acyliminium Pictet−Spengler Reactions as Crossroads to Scaffold Diversity
2004 StandoutNobel
Prostanoid Receptors: Structures, Properties, and Functions
1999 Standout
Biosynthesis of 15-deoxy-Δ12,14-PGJ2 and the ligation of PPARγ
2003
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
One-Pot, Modular Approach to Functionalized Ketones via Nucleophilic Addition of Alkyllithium Reagents to Benzamides and Pd-Catalyzed α-Arylation
2016 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Synthesis of (2-Oxoindolin-3-ylidene)methyl Acetates Involving a C−H Functionalization Process
2008
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
Discovery, Optimization, and Biological Evaluation of 5-(2-(Trifluoromethyl)phenyl)indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists
2014 StandoutNobel
Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.
1994 Standout
Transition Metal-Catalyzed Direct Arylation of Substrates with Activated sp3-Hybridized C−H Bonds and Some of Their Synthetic Equivalents with Aryl Halides and Pseudohalides
2009
Reactions of some nitrogen heterocycles with chlorodifluoromethane under conditions of phase-transfer catalysis
2005
Occurrence of 9-deoxy-delta 9,delta 12-13,14-dihydroprostaglandin D2 in human urine.
1988
In Silico Prediction of Volume of Distribution in Human Using Linear and Nonlinear Models on a 669 Compound Data Set
2009
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Ascaris suum-Derived Products Induce Human Neutrophil Activation via a G Protein-Coupled Receptor That Interacts with the Interleukin-8 Receptor Pathway
2001
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
2016 Standout
Transition-Metal-Catalyzed C−S, C−Se, and C−Te Bond Formation via Cross-Coupling and Atom-Economic Addition Reactions
2011 Standout
Discovery and Evaluation of Clinical Candidate AZD3759, a Potent, Oral Active, Central Nervous System-Penetrant, Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
2015
Heterogeneous Catalysts for the One-Pot Synthesis of Chemicals and Fine Chemicals
2010
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
2012 Standout
Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis
2011
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Tetranor PGDM, an Abundant Urinary Metabolite Reflects Biosynthesis of Prostaglandin D2 in Mice and Humans
2007
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
2009 Standout
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Synthesis of Stereodefined 3-Alkylideneoxindoles by Palladium-catalyzed Reactions of 2-(Alkynyl)aryl Isocyanates with Thiols and Alcohols
2009
A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.
1990 Standout
Trovafloxacin is active against Toxoplasma gondii
1996
Heme-Containing Oxygenases
1996 Standout
Prostaglandins and Inflammation
2011 Standout
Chemistry Takes a Bath: Reactions in Aqueous Media
2018 StandoutNobel
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Assembly of 3-Acyloxindoles via CuI/l -Proline-Catalyzed Intramolecular Arylation of β-Keto Amides
2006
Crystal Structure of Human Prostaglandin F Synthase (AKR1C3),
2004
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of Theodore E. Liston being referenced
Pharmacokinetics and pharmacodynamics of the leukotriene B4 receptor antagonist CP‐105,696 in man following single oral administration
1998
Species Independence in Brain Tissue Binding Using Brain Homogenates
2011
N-carbamoyl analogs of zafirlukast: Potent receptor antagonists of leukotriene D4
1998
Pharmacokinetics and safety of trovafloxacin (CP-99, 219), a new quinolone antibiotic, following adminstration of single oral doses to healthy male volunteers
1995
Biphasic Effect of Dexamethasone on Urinary Prostaglandins in Rats: Relation to Alterations in Renal Medulla Triglycerides and Prostaglandin Metabolism*
1987
Development of a new permeability assay using low‐efflux MDCKII cells
2011
Transformation of prostaglandin D2 to 9 alpha, 11 beta-(15S)-trihydroxyprosta-(5Z,13E)-dien-1-oic acid (9 alpha, 11 beta-prostaglandin F2): a unique biologically active prostaglandin produced enzymatically in vivo in humans.
1985
Metabolic fate of radiolabeled prostaglandin D2 in a normal human male volunteer.
1985
The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data.
1997
The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
1997
Discovery of the Hemifumarate and (α-l -Alanyloxy)methyl Ether as Prodrugs of an Antirheumatic Oxindole: Prodrugs for the Enolic OH Group
1996
A High-Capacity LC/MS System for the Bioanalysis of Samples Generated from Plate-Based Metabolic Screening
2001