Standout Papers
- Identification of copy number variants in whole-genome data using Reference Coverage Profiles (2015)
- The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death (1994)
- Molecular characterization of the early activation antigen CD69: A type II membrane glycoprotein related to a family of natural killer cell activation antigens (1993)
Citation Impact
Citing Papers
Quantitative variability of 342 plasma proteins in a human twin population
2015
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Scalable Data Analysis in Proteomics and Metabolomics Using BioContainers and Workflows Engines
2019
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Data Management of Sensitive Human Proteomics Data: Current Practices, Recommendations, and Perspectives for the Future
2021
Identification and Characterization of a Ligand-independent Oligomerization Domain in the Extracellular Region of the CD95 Death Receptor
1999
Estimation of Absolute Protein Quantities of Unlabeled Samples by Selected Reaction Monitoring Mass Spectrometry
2011
Reproducible and Consistent Quantification of the Saccharomyces cerevisiae Proteome by SWATH-mass spectrometry *
2015
Proteomics data repositories: Providing a safe haven for your data and acting as a springboard for further research
2010
Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics
2012
PRIDE Inspector Toolsuite: Moving Toward a Universal Visualization Tool for Proteomics Data Standard Formats and Quality Assessment of ProteomeXchange Datasets
2015
Identification and Characterization of an IκB Kinase
1997
A role for CD95 ligand in preventing graft rejection
1995 StandoutNature
Membrane Oligomerization and Cleavage Activates the Caspase-8 (FLICE/MACHα1) Death Signal
1998
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
1997 Nature
Requirement of Cysteine-rich Repeats of the Fas Receptor for Binding by the Fas Ligand
1997
Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands
1996 Nature
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins
1995
Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis
1997 Nobel
Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α
1998
LIGHT, a New Member of the TNF Superfamily, and Lymphotoxin α Are Ligands for Herpesvirus Entry Mediator
1998
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo
1999 Standout
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
1995
A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
1994
Functions of CD40 on B cells, dendritic cells and other cells
1997
The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation
1995 Standout
A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans
2010
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
2000
Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family
1996 Standout
The Proteomics Identifications (PRIDE) database and associated tools: status in 2013
2012 Standout
Identity of Osteoclastogenesis Inhibitory Factor (OCIF) and Osteoprotegerin (OPG): A Mechanism by which OPG/OCIF Inhibits Osteoclastogenesisin Vitro1
1998
Sensitizing Anthrax Lethal Toxin-resistant Macrophages to Lethal Toxin-induced Killing by Tumor Necrosis Factor-α
2003 StandoutNobel
A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40
1995
TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival
1997
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family
1993 Standout
Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
2011 Standout
The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen
1994
Selected reaction monitoring–based proteomics: workflows, potential, pitfalls and future directions
2012
Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
1995
The Structural Basis for the Recognition of Diverse Receptor Sequences by TRAF2
1999
An Evolutionary and Functional Approach to the TNF Receptor/Ligand Family
1994 StandoutNobel
In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
1995
CAR1, a TNFR–Related Protein, Is a Cellular Receptor for Cytopathic Avian Leukosis–Sarcoma Viruses and Mediates Apoptosis
1996
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
1995
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
1999
The Hallmarks of Cancer
2000 Standout
Tumor necrosis factor receptor-associated factors (TRAFs)—a family of adapter proteins that regulates life and death
1998
MS-GF+ makes progress towards a universal database search tool for proteomics
2014
Fas and Fas Ligand: A Death Factor and Its Receptor
1994
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
1997
RANK is essential for osteoclast and lymph node development
1999
Eph Receptors and Ligands Comprise Two Major Specificity Subclasses and Are Reciprocally Compartmentalized during Embryogenesis
1996
RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
1995
The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain
1997
FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
1995
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Contenders in FasL/TNF death signaling
1995
TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL
1997
Dimerization of cell surface receptors in signal transduction
1995
Identification and characterization of a new member of the TNF family that induces apoptosis
1995 Standout
neXtProt: a knowledge platform for human proteins
2011
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
The CD40 Antigen and its Ligand
1994
Tumor necrosis factor receptor superfamily members and their ligands
1994
TWEAK, a New Secreted Ligand in the Tumor Necrosis Factor Family That Weakly Induces Apoptosis
1997
mzML—a Community Standard for Mass Spectrometry Data
2010
Molecular Cloning of Two Novel Transmembrane Ligands for Eph-Related Kinases (LERKS) that are Related to LERK-2
1996
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
2000 Nature
Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
2011 StandoutNobel
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
2000
2016 update of the PRIDE database and its related tools
2015 Standout
TRAMP, a Novel Apoptosis-Mediating Receptor with Sequence Homology to Tumor Necrosis Factor Receptor 1 and Fas(Apo-1/CD95)
1997
Glycoproteomic Analysis of Prostate Cancer Tissues by SWATH Mass Spectrometry Discovers N-acylethanolamine Acid Amidase and Protein Tyrosine Kinase 7 as Signatures for Tumor Aggressiveness
2014
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Targeted Data Extraction of the MS/MS Spectra Generated by Data-independent Acquisition: A New Concept for Consistent and Accurate Proteome Analysis
2012 Standout
TROY, a Newly Identified Member of the Tumor Necrosis Factor Receptor Superfamily, Exhibits a Homology with Edar and Is Expressed in Embryonic Skin and Hair Follicles
2000
Mass spectrometric protein maps for biomarker discovery and clinical research
2013
Apoptosis control by death and decoy receptors
1999
Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Reference Population
2014
A death-domain-containing receptor that mediates apoptosis
1996 Nature
The entorhinal grid map is discretized
2012 StandoutNatureNobel
The human secretome atlas initiative: Implications in health and disease conditions
2013
Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL
1996 Standout
The Fas Death Factor
1995 StandoutScience
Mutations in the human homologue of mouse dl cause autosomal recessive and dominant hypohidrotic ectodermal dysplasia
1999
N-Glycoprotein SRMAtlas
2013
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
TNF-Dependent Recruitment of the Protein Kinase RIP to the TNF Receptor-1 Signaling Complex
1996
A Mass Spectrometric-Derived Cell Surface Protein Atlas
2015
Sema4C, a Transmembrane Semaphorin, Interacts with a Post-synaptic Density Protein, PSD-95
2001
Anatomy of TRAF2
1996
The c-kit+ Maturation Pathway in Mouse Thymic T Cell Development: Lineages and Selection
1996
Quantitative Analysis of Fission Yeast Transcriptomes and Proteomes in Proliferating and Quiescent Cells
2012
Nuk Controls Pathfinding of Commissural Axons in the Mammalian Central Nervous System
1996
CD30 Is a CD40-Inducible Molecule that Negatively Regulates CD40-Mediated Immunoglobulin Class Switching in Non-Antigen-Selected Human B Cells
1998
Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB
1996
Mass spectrometry-based proteomics for systems biology
2011
Absolute Proteome Composition and Dynamics during Dormancy and Resuscitation of Mycobacterium tuberculosis
2015
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
A complete mass-spectrometric map of the yeast proteome applied to quantitative trait analysis
2013 Nature
The TNF and TNF Receptor Superfamilies
2001 Standout
Panorama Public: A Public Repository for Quantitative Data Sets Processed in Skyline
2018
Death Receptor 5, a New Member of the TNFR Family, and DR4 Induce FADD-Dependent Apoptosis and Activate the NF-κB Pathway
1997
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
1997
A public repository for mass spectrometry imaging data
2014
Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
1995
TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways
1996 Standout
TRANCE Is a Novel Ligand of the Tumor Necrosis Factor Receptor Family That Activates c-Jun N-terminal Kinase in T Cells
1997
A Face in the Crowd: Recognizing Peptides Through Database Search
2011
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
1997 StandoutNature
The neXtProt knowledgebase on human proteins: current status
2015
Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice
1997
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
1998 Nature
The mzIdentML Data Standard Version 1.2, Supporting Advances in Proteome Informatics
2017
Analysis of High Accuracy, Quantitative Proteomics Data in the MaxQB Database
2012
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
gld/gld mice are unable to express a functional ligand for Fas
1994 StandoutNobel
TRANCE, a TNF Family Member, Is Differentially Expressed on T Cell Subsets and Induces Cytokine Production in Dendritic Cells
1999 StandoutNobel
Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project
2020
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Divergent signalling via APO-1/Fas and the TNF receptor, two homologous molecules involved in physiological cell death.
1994
The jPOST environment: an integrated proteomics data repository and database
2018
Identifying novel biomarkers through data mining—A realistic scenario?
2014
TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor
1997 StandoutNobel
Exploring the potential of public proteomics data
2015
MRMaid 2.0: Mining PRIDE for Evidence-Based SRM Transitions
2012
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
1998 StandoutScienceNobel
Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt
1997
Fas ligand mediates activation-induced cell death in human T lymphocytes.
1995 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases.
1995
Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors
1997 StandoutScience
TRAF2-Mediated Activation of NF-κB by TNF Receptor 2 and CD40
1995 Science
Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.
1996
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factor
1998
Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase.
1995
Metrics for the Human Proteome Project 2015: Progress on the Human Proteome and Guidelines for High-Confidence Protein Identification
2015
The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
2021 Standout
CTLA4 mediates antigen-specific apoptosis of human T cells.
1995
Protein Analysis by Shotgun/Bottom-up Proteomics
2013
The Early Progenitors of Mouse Dendritic Cells and Plasmacytoid Predendritic Cells Are within the Bone Marrow Hemopoietic Precursors Expressing Flt3
2003
Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death
1995
Tyrosine Phosphorylation of Transmembrane Ligands for Eph Receptors
1997 StandoutScience
Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family
1997
CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP.
1997
FAP-1: A Protein Tyrosine Phosphatase That Associates with Fas
1995 Science
Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice
1997
Version 4.0 of PaxDb: Protein abundance data, integrated across model organisms, tissues, and cell‐lines
2015
Making proteomics data accessible and reusable: Current state of proteomics databases and repositories
2014
Phosphorylation and Assembly of Glutamate Receptors After Brain Ischemia
2012
Identification of a Protein with Homology to hsp90 That Binds the Type 1 Tumor Necrosis Factor Receptor
1995
Death Receptors: Signaling and Modulation
1998 StandoutScience
Proteomics and the Analysis of Proteomic Data: 2013 Overview of Current Protein‐Profiling Technologies
2013
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
1994
Fas ligation induces apoptosis of CD40-activated human B lymphocytes.
1995
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL
1998 Standout
Protection from Fas-Mediated Apoptosis by a Soluble Form of the Fas Molecule
1994 Science
Proteomics and the Analysis of Proteomic Data: An Overview of Current Protein‐Profiling Technologies
2005
ELF-2, a New Member of the Eph Ligand Family, Is Segmentally Expressed in Mouse Embryos in the Region of the Hindbrain and Newly Forming Somites
1995
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Cross-linking CD40 on B cells preferentially induces stress-activated protein kinases rather than mitogen-activated protein kinases.
1996
Hematopoietic cytokines
2008
Expression of the functional soluble form of human fas ligand in activated lymphocytes.
1995
Applications of targeted proteomics in systems biology and translational medicine
2015
Quantitative measurements of N ‐linked glycoproteins in human plasma by SWATH ‐MS
2013
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
1995 ScienceNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
1996
Targeted methods for quantitative analysis of protein glycosylation
2014
Aggregation of the intracellular domain of the type 1 tumor necrosis factor receptor defined by the two-hybrid system.
1994
Trans‐Proteomic Pipeline, a standardized data processing pipeline for large‐scale reproducible proteomics informatics
2015
Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk.
1995
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Dendritic Cells: Unique Leukocyte Populations Which Control the Primary Immune Response
1997
Protein Inference Using PIA Workflows and PSI Standard File Formats
2018
PIA: An Intuitive Protein Inference Engine with a Web-Based User Interface
2015
iProX: an integrated proteome resource
2018
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
How to submit MS proteomics data to ProteomeXchange via the PRIDE database
2014
Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.
1994 StandoutNobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
An Inherited Disorder of Lymphocyte Apoptosis: The Autoimmune Lymphoproliferative Syndrome
1999
RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis.
1996
TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.
1996 Nobel
Glycobioinformatics: Current strategies and tools for data mining in MS ‐based glycoproteomics
2012
Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death
1999
TANK Potentiates Tumor Necrosis Factor Receptor-Associated Factor-Mediated c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase Activation through the Germinal Center Kinase Pathway
1999
Chemical Glycoproteomics
2016 StandoutNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
LIGHT, a TNF-Like Molecule, Costimulates T Cell Proliferation and Is Required for Dendritic Cell-Mediated Allogeneic T Cell Response
2000
Works of Terry Farrah being referenced
The Mtb Proteome Library: A Resource of Assays to Quantify the Complete Proteome of Mycobacterium tuberculosis
2013
Using the Human Plasma PeptideAtlas to Study Human Plasma Proteins
2011
Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
1993
A guided tour of the Trans‐Proteomic Pipeline
2010
Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor
1993
A High-Confidence Human Plasma Proteome Reference Set with Estimated Concentrations in PeptideAtlas
2011
High-throughput generation of selected reaction-monitoring assays for proteins and proteomes
2009
A Poxvirus-Encoded Semaphorin Induces Cytokine Production from Monocytes and Binds to a Novel Cellular Semaphorin Receptor, VESPR
1998
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor
1993
Trans‐Proteomic Pipeline supports and improves analysis of electron transfer dissociation data sets
2010
State of the Human Proteome in 2013 as Viewed through PeptideAtlas: Comparing the Kidney, Urine, and Plasma Proteomes for the Biology- and Disease-Driven Human Proteome Project
2013
2012
Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors.
1994
Reproducible Quantification of Cancer-Associated Proteins in Body Fluids Using Targeted Proteomics
2012
Tiered Human Integrated Sequence Search Databases for Shotgun Proteomics
2016
The State of the Human Proteome in 2012 as Viewed through PeptideAtlas
2012
Using PeptideAtlas, SRMAtlas, and PASSEL: Comprehensive Resources for Discovery and Targeted Proteomics
2014
A standardized framing for reporting protein identifications in mzIdentML 1.2
2014