Citation Impact
Citing Papers
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival
2014 StandoutNobel
The Thioxotriazole Copper(II) Complex A0 Induces Endoplasmic Reticulum Stress and Paraptotic Death in Human Cancer Cells
2009
The dynamics of monocytes and microglia in Alzheimer’s disease
2015
LPS- induced inflammation exacerbates phospho-tau pathology in rTg4510 mice
2010
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
2019
Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy
2018
The intestinal anti-inflammatory effect of minocycline in experimental colitis involves both its immunomodulatory and antimicrobial properties
2010
Fractalkine activates NRF2/NFE2L2 and heme oxygenase 1 to restrain tauopathy-induced microgliosis
2013
Therapeutic effects of glatiramer acetate and grafted CD115+monocytes in a mouse model of Alzheimer’s disease
2015
Nrf2 degron-fused reporter system: a new tool for specific evaluation of Nrf2 inducers
2011
Minocycline attenuates experimental colitis in mice by blocking expression of inducible nitric oxide synthase and matrix metalloproteinases
2009
Molecular Architecture of the Mouse Nervous System
2018 Standout
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
2009
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease
2006
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Microglial clearance function in health and disease
2008
Selective ablation of bone marrow‐derived dendritic cells increases amyloid plaques in a mouse Alzheimer's disease model
2007
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Mechanisms Underlying the Rapid Peroxisome Proliferator-Activated Receptor-γ-Mediated Amyloid Clearance and Reversal of Cognitive Deficits in a Murine Model of Alzheimer's Disease
2012
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Origin of Microglia: Current Concepts and Past Controversies
2015
Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain
2019
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Toll-Like Receptor 2 Acts as a Natural Innate Immune Receptor to Clear Amyloid β1–42and Delay the Cognitive Decline in a Mouse Model of Alzheimer's Disease
2008
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
Copper complexes as therapeutic agents
2011
Inflammation, microglia, and alzheimer's disease
2009
Microglia in the degenerating brain are capable of phagocytosis of beads and of apoptotic cells, but do not efficiently remove PrPSc, even upon LPS stimulation
2010
Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism
2016 Standout
NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology
2017
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
2007
Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases
2013
Invasion of Hematopoietic Cells into the Brain of Amyloid Precursor Protein Transgenic Mice
2005
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Microglial Activation is Required for Aβ Clearance After Intracranial Injection of Lipopolysaccharide in APP Transgenic Mice
2007
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
2007
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Recent advances in MMP inhibitor design
2006
Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract
2010
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
2008
Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy
2017
NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
2019 Standout
Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia
2014
Sustained hippocampal IL-1β overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology
2007
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis
2010
MicroRNA-210: A unique and pleiotropic hypoxamir
2010
New insights into the role of TREM2 in Alzheimer’s disease
2018
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Increased Alzheimer's disease–like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy
2014
The Triggering Receptor Expressed on Myeloid Cells 2 Binds Apolipoprotein E
2015
Debris clearance by microglia: an essential link between degeneration and regeneration
2008
Alzheimer's Disease
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Role of toll-like receptor signalling in A uptake and clearance
2006
Distinct and Non-Redundant Roles of Microglia and Myeloid Subsets in Mouse Models of Alzheimer's Disease
2011
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
2010
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
MicroRNAs — the micro steering wheel of tumour metastases
2009
Toll-Like Receptor 2 Signaling in Response to Brain Injury: An Innate Bridge to Neuroinflammation
2006
An Integrated Approach for Experimental Target Identification of Hypoxia-induced miR-210
2009
Gene expression and hypoxia in breast cancer
2011
miR‐210: More than a silent player in hypoxia
2011
Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
2014
Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival
2009
Functional diversity of astrocytes in neural circuit regulation
2016
The role of microglia in amyloid clearance from the AD brain
2010
Powerful beneficial effects of macrophage colony-stimulating factor on -amyloid deposition and cognitive impairment in Alzheimer's disease
2008
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
2011
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
Neuroprotective role of the innate immune system by microglia
2007
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
CD11c/EYFP transgene illuminates a discrete network of dendritic cells within the embryonic, neonatal, adult, and injured mouse brain
2008 StandoutNobel
TREM2-Transduced Myeloid Precursors Mediate Nervous Tissue Debris Clearance and Facilitate Recovery in an Animal Model of Multiple Sclerosis
2007
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
New Insights on NOX Enzymes in the Central Nervous System
2013
Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease
2016
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis
2019
Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI
2016
MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia
2011
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
Biomedical applications of copper ionophores
2020
Matrix Metalloproteinase Inhibitors Attenuate Neuroinflammation Following Focal Cerebral Ischemia in Mice
2011
Spinal cord oligodendrocyte‐derived alarmin IL‐33 mediates neuropathic pain
2015
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Multiple Sclerosis
2018 Standout
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Changing Face of Microglia
2010 Science
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Minocycline: far beyond an antibiotic
2013 Standout
Are NSAIDs useful to treat Alzheimer’s disease or mild cognitive impairment?
2010
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Microglia Potentiate Damage to Blood–Brain Barrier Constituents
2006
A critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease
2014
The Biology of Proteostasis in Aging and Disease
2015
Advances in Copper Complexes as Anticancer Agents
2013 Standout
A Multifunctional Lentiviral-Based Gene Knockdown with Concurrent Rescue that Controls for Off-Target Effects of RNAi
2010
Stress-Activated Cap'n'collar Transcription Factors in Aging and Human Disease
2010
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood–Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype
2017
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
Physiology of Microglia
2011 Standout
Clearance of Amyloid-β Peptides By Microglia and Macrophages: the Issue of What, When and Where
2012
LEF-1 is crucial for neutrophil granulocytopoiesis and its expression is severely reduced in congenital neutropenia
2006 Standout
Lack of Association between Nuclear Factor Erythroid-Derived 2-Like 2 Promoter Gene Polymorphisms and Oxidative Stress Biomarkers in Amyotrophic Lateral Sclerosis Patients
2014
Works of Tarja Malm being referenced
Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease
2010
Retinal Degeneration In A Mouse Model Of CLN5 Disease Is Associated With Compromised Autophagy
2017
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to β-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
2004
Hypoxia induces microRNA miR‐210 in vitro and in vivo
2008
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid
2008
Complex regulation of acute and chronic neuroinflammatory responses in mouse models deficient for nuclear factor kappa B p50 subunit
2013
Pyrrolidine Dithiocarbamate Activates Akt and Improves Spatial Learning in APP/PS1 Mice without Affecting β-Amyloid Burden
2007
The role and therapeutic potential of monocytic cells in Alzheimer's disease
2010
Transplanted astrocytes internalize deposited β‐amyloid peptides in a transgenic mouse model of Alzheimer's disease
2007
Deletion of Nuclear Factor kappa B p50 Subunit Decreases Inflammatory Response and Mildly Protects Neurons from Transient Forebrain Ischemia-induced Damage
2016
Exosomes as new diagnostic tools in CNS diseases
2015
Nuclear Receptors License Phagocytosis by Trem2+Myeloid Cells in Mouse Models of Alzheimer's Disease
2015
Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production
2012
Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration
2018
Pyrrolidine Dithiocarbamate Inhibits Induction of Immunoproteasome and Decreases Survival in a Rat Model of Amyotrophic Lateral Sclerosis
2006
Targeting Glycogen Synthase Kinase‐3β for Therapeutic Benefit against Oxidative Stress in Alzheimer′s Disease: Involvement of the Nrf2‐ARE Pathway
2011
Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta Clearance
2012
Minocycline reduces engraftment and activation of bone marrow‐derived cells but sustains their phagocytic activity in a mouse model of Alzheimer's disease
2008
Interleukin-33 treatment reduces secondary injury and improves functional recovery after contusion spinal cord injury
2014
Stable RNA interference: comparison of U6 and H1 promoters in endothelial cells and in mouse brain
2006
Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease
2009
Nrf2 Regulates Neurogenesis and Protects Neural Progenitor Cells Against Aβ Toxicity
2014
Minocycline Protects against Permanent Cerebral Ischemia in Wild Type but Not in Matrix Metalloprotease-9-Deficient Mice
2005
β-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or β-amyloid deposits
2006