Citation Impact
Citing Papers
Regional differences in cellular mechanisms of adipose tissue gain with overfeeding
2010
Galactose‐modified duocarmycin prodrugs as senolytics
2020
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
2007 Standout
Intrinsic Differences in Adipocyte Precursor Cells From Different White Fat Depots
2012
Adipose tissue stem cells meet preadipocyte commitment: going back to the future
2011
Impaired immune surveillance accelerates accumulation of senescent cells and aging
2018
Recruited vs. nonrecruited molecular signatures of brown, “brite,” and white adipose tissues
2011
Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
2022 StandoutNobel
Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes
2016
Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications
2012
Epigenetic regulation of adipogenesis
2012
Clinical and pathophysiological consequences of abdominal adiposity and abdominal adipose tissue depots
2003
Effects of androgens on adipocyte differentiation and adipose tissue explant metabolism in men and women
2009
A Novel Indication for Panobinostat as a Senolytic Drug in NSCLC and HNSCC
2017
Inflammatory links between obesity and metabolic disease
2011 Standout
Brown and beige fat: development, function and therapeutic potential
2013 Standout
Identification and Importance of Brown Adipose Tissue in Adult Humans
2009 Standout
The Insulin-Like Growth Factors in Adipogenesis and Obesity
2012
Cellular senescence: when bad things happen to good cells
2007 Standout
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
Developmental Origins of the Adipocyte Lineage: New Insights from Genetics and Genomics Studies
2011
Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes
2015
Fat tissue, aging, and cellular senescence
2010
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
The metabolic syndrome
2010 Standout
Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2−/− mice following ischemic injury
2006
Hallmarks of aging: An expanding universe
2023 Standout
Metabolic Control of Longevity
2016
Senolytic activity of piperlongumine analogues: Synthesis and biological evaluation
2018
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
The endoplasmic reticulum stress response in aging and age-related diseases
2012
Hypertrophy and hyperplasia of abdominal adipose tissues in women
2007
Senescent cells: an emerging target for diseases of ageing
2017
The Relationship of Omental and Subcutaneous Adipocyte Size to Metabolic Disease in Severe Obesity
2010
Senescent Cells, Tumor Suppression, and Organismal Aging: Good Citizens, Bad Neighbors
2005 Standout
PTEN Loss in the Myf5 Lineage Redistributes Body Fat and Reveals Subsets of White Adipocytes that Arise from Myf5 Precursors
2012
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
2019
Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study
2019 Standout
Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
2017
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
PRDM16 controls a brown fat/skeletal muscle switch
2008 StandoutNature
Identification of senescent cell surface targetable protein DPP4
2017
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Adipokines in inflammation and metabolic disease
2011 Standout
RNAi screening for fat regulatory genes with SRS microscopy
2011 StandoutNobel
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Defective Signaling in the JAK-STAT Pathway Tracks with Chronic Inflammation and Cardiovascular Risk in Aging Humans
2016
Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?
2007
Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues
2020
A progeroid syndrome in mice is caused by defects in A-type lamins
2003 Nature
Tracking adipogenesis during white adipose tissue development, expansion and regeneration
2013
Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis
2015
Identification of HSP90 inhibitors as a novel class of senolytics
2017
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Measuring committed preadipocytes in human adipose tissue from severely obese patients by using adipocyte fatty acid binding protein
2004
The end of AIDS: HIV infection as a chronic disease
2013 Standout
T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
2012 StandoutNobel
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
2012 Standout
Mechanisms and Metabolic Implications of Regional Differences among Fat Depots
2013
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae)
2018 StandoutNobel
Stem cells, ageing and the quest for immortality
2006 StandoutNature
Understanding the Odd Science of Aging
2005 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Sex‐ and Depot‐Dependent Differences in Adipogenesis in Normal‐Weight Humans
2010
Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
2018 Nature
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
2020
From discoveries in ageing research to therapeutics for healthy ageing
2019 Nature
Inflammaging and ‘Garb-aging’
2016
Senescent cell turnover slows with age providing an explanation for the Gompertz law
2019
What We Talk About When We Talk About Fat
2014 Standout
Pathways of adipose tissue androgen metabolism in women: depot differences and modulation by adipogenesis
2008
Adipocyte differentiation from the inside out
2006 Standout
The role of senescent cells in ageing
2014 StandoutNature
Beneficial Effects of Subcutaneous Fat Transplantation on Metabolism
2008
Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis
2016
The senescence-associated secretory phenotype is potentiated by feedforward regulatory mechanisms involving Zscan4 and TAK1
2018
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Adipose tissue remodeling and obesity
2011
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Transplantation of adipose tissue and stem cells: role in metabolism and disease
2010
Osteoarthritis
2019 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
PAPP‐A: a new anti‐aging target?
2010
Development and Maintenance of Regulatory T cells
2013 StandoutNobel
Frailty in elderly people
2013 Standout
Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest
2018
Unmasking senescence: context-dependent effects of SASP in cancer
2019
Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome
2009
Adipose Tissue as an Endocrine Organ
2004 Standout
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
2009 Standout
Research Agenda for Frailty in Older Adults: Toward a Better Understanding of Physiology and Etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults
2006
Age-Associated Increase in Cytokine Production During Systemic Inflammation—II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue
2014
Developmental Origin of Fat: Tracking Obesity to Its Source
2007
Cellular senescence: from physiology to pathology
2014 Standout
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
2020 StandoutNobel
Pathophysiology of Human Visceral Obesity: An Update
2013 Standout
Inhibition of p38MAPK Increases Adipogenesis From Embryonic to Adult Stages
2006
Inhibition of sphingosine 1-phosphate signaling ameliorates murine nonalcoholic steatohepatitis
2016
Skeletal muscle satellite cells can spontaneously enter an alternative mesenchymal pathway
2004
Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty
2016
Adipose Tissue-Derived Factors: Impact on Health and Disease
2006
Hsp90 inhibitors as senolytic drugs to extend healthy aging
2018
Evidence for a role of developmental genes in the origin of obesity and body fat distribution
2006
Adipose Tissue Endothelial Cells From Obese Human Subjects: Differences Among Depots in Angiogenic, Metabolic, and Inflammatory Gene Expression and Cellular Senescence
2010
Fibroblast Growth Factor 1
2004
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
The curcumin analog EF24 is a novel senolytic agent
2019
Genome-Wide Profiling of Peroxisome Proliferator-Activated Receptor γ in Primary Epididymal, Inguinal, and Brown Adipocytes Reveals Depot-Selective Binding Correlated with Gene Expression
2012
Diagnosis and Treatment of Hip and Knee Osteoarthritis
2021 Standout
Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation
2005
Strategies targeting cellular senescence
2018
Molecular pathways of senescence regulate placental structure and function
2019
A versatile drug delivery system targeting senescent cells
2018
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice
2016
Depot-Specific Differences in Adipogenic Progenitor Abundance and Proliferative Response to High-Fat Diet
2009
Spermidine in health and disease
2018 StandoutScience
Lipotoxicity and the gut-liver axis in NASH pathogenesis
2017
Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
2019
Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity
2020
Peroxisome-proliferator-activated receptor γ suppresses Wnt/β-catenin signalling during adipogenesis
2003
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
2007 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Discovery of piperlongumine as a potential novel lead for the development of senolytic agents
2016
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
2016
From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis
2010 Standout
Inflammation and the depot-specific secretome of human preadipocytes
2015
Noncanonical Wnt Signaling Promotes Obesity-Induced Adipose Tissue Inflammation and Metabolic Dysfunction Independent of Adipose Tissue Expansion
2014
Targeting senescent cells in translational medicine
2019
IPF lung fibroblasts have a senescent phenotype
2017
Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism
2017
microRNAs regulate adipocyte differentiation
2013
The chemistry of senescence
2019
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
2016 Science
p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
2017
An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program
2019
Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat
2010
Pathogenesis of pancreatic cancer exosome-induced lipolysis in adipose tissue
2015
PPARγ accelerates cellular senescence by inducing p16INK4α expression in human diploid fibroblasts
2008
Proinflammatory Phenotype of Perivascular Adipocytes
2009
De novo generation of white adipocytes from the myeloid lineage via mesenchymal intermediates is age, adipose depot, and gender specific
2010
Works of Tamar Pirtskhalava being referenced
Octanoate Attenuates Adipogenesis in 3T3-L1 Preadipocytes
2002
Aging, Depot Origin, and Preadipocyte Gene Expression
2010
Targeting cellular senescence prevents age-related bone loss in mice
2017
Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice
2016
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess
2014
Adipogenesis and aging: does aging make fat go MAD?
2002
Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots
2004
Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns
2006
Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity
2006
Increased TNFα and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis
2007
Targeting senescent cells enhances adipogenesis and metabolic function in old age
2015
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
2015
Fat Depot–Specific Characteristics Are Retained in Strains Derived From Single Human Preadipocytes
2006
Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
2014
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
2015
Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
2016
Increased CUG Triplet Repeat-binding Protein-1 Predisposes to Impaired Adipogenesis with Aging
2006
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
2017
Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes
2002
Deleted in B reast C ancer 1 regulates cellular senescence during obesity
2014