Standout Papers
Citation Impact
Citing Papers
Argonaute2 Is the Catalytic Engine of Mammalian RNAi
2004 StandoutScience
Regulation of neddylation and deneddylation of cullin1 in SCF Skp2 ubiquitin ligase by F-box protein and substrate
2006 Nobel
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Bioluminescent imaging of Cdk2 inhibition in vivo
2004 StandoutNobel
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Determinants of Nuclear and Cytoplasmic Ubiquitin-mediated Degradation of MyoD
2003 StandoutNobel
Starvation Induced Cell Death in Autophagy-Defective Yeast Mutants Is Caused by Mitochondria Dysfunction
2011 StandoutNobel
A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1
2003 StandoutNobel
The spindle checkpoint requires cyclin-dependent kinase activity
2003
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit
2006 StandoutNobel
Ubiquitin-mediated degradation of cellular proteins in health and disease
2002 StandoutNobel
APC/CCdc20 Controls the Ubiquitin-Mediated Degradation of p21 in Prometaphase
2007
The anaphase promoting complex/cyclosome: a machine designed to destroy
2006
Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
2008 Standout
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity
2012 StandoutNobel
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
2000
Three Different Binding Sites of Cks1 Are Required for p27-Ubiquitin Ligation
2002 StandoutNobel
Increased ubiquitin immunoreactivity in unstable atherosclerotic plaques associated with acute coronary syndromes
2002 StandoutNobel
Proteolysis and the cell cycle: with this RING I do thee destroy
2000
Emi1 Is a Mitotic Regulator that Interacts with Cdc20 and Inhibits the Anaphase Promoting Complex
2001
Degradation of the E7 human papillomavirus oncoprotein by the ubiquitin-proteasome system: targeting via ubiquitination of the N-terminal residue
2000 StandoutNobel
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
2010 StandoutNobel
The Cyclin-Ubiquitin Ligase Activity of Cyclosome/APC Is Jointly Activated by Protein Kinases Cdk1-Cyclin B and Plk
2002 StandoutNobel
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Phosphorylation of Cdc20 is required for its inhibition by the spindle checkpoint
2003
p21 in cancer: intricate networks and multiple activities
2009 Standout
The WD40 Propeller Domain of Cdh1 Functions as a Destruction Box Receptor for APC/C Substrates
2005
Proteomic analysis of post-translational modifications
2003 Standout
Phosphorylation of Cdc20 by Bub1 Provides a Catalytic Mechanism for APC/C Inhibition by the Spindle Checkpoint
2004
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Mitotic regulation of the human anaphase-promoting complex by phosphorylation
2003
The anaphase-promoting complex: it's not just for mitosis any more
2002
The Anaphase-Promoting Complex
2002
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Degradation of the Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) by the Ubiquitin-Proteasome Pathway
2000 StandoutNobel
The eukaryotic linear motif resource ELM: 10 years and counting
2013
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
2001 StandoutNobel
Modulation of the Mitotic Regulatory Network by APC-Dependent Destruction of the Cdh1 Inhibitor Acm1
2008
Hypoxia and cell cycle regulation of the von Hippel–Lindau tumor suppressor
2010
The ubiquitin system
2000 StandoutNobel
Modes of regulation of ubiquitin-mediated protein degradation
2000 StandoutNobel
APC/C and SCF: Controlling Each Other and the Cell Cycle
2004
The spindle-assembly checkpoint in space and time
2007 Standout
Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2
2001
Phosphorylation by Cdc28 Activates the Cdc20-Dependent Activity of the Anaphase-Promoting Complex
2000
An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells
2007 Nobel
Anaphase-Promoting Complex/Cyclosome–Dependent Proteolysis of Human Cyclin a Starts at the Beginning of Mitosis and Is Not Subject to the Spindle Assembly Checkpoint
2001 StandoutNobel
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Mechanisms Underlying Ubiquitination
2001 Standout
RING Domain E3 Ubiquitin Ligases
2009 Standout
Ubiquitin-mediated proteolysis: biological regulation via destruction
2000 StandoutNobel
β-Arrestin-1 Competitively Inhibits Insulin-Induced Ubiquitination and Degradation of Insulin Receptor Substrate 1
2004 StandoutNobel
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
2005
New B-type cyclin synthesis is required between meiosis I and II duringXenopusoocyte maturation
2001 StandoutNobel
Mechanisms and regulation of the degradation of cyclin B
1999 StandoutNobel
A Conserved Cyclin-Binding Domain Determines Functional Interplay between Anaphase-Promoting Complex–Cdh1 and Cyclin A-Cdk2 during Cell Cycle Progression
2001
Oxidative stress‐related increase in ubiquitination in early coronary atherogenesis
2003 StandoutNobel
Nonperiodic Activity of the Human Anaphase-Promoting Complex–Cdh1 Ubiquitin Ligase Results in Continuous DNA Synthesis Uncoupled from Mitosis
2000
Mitotic Regulation of the APC Activator Proteins CDC20 and CDH1
2000
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity
2000 Standout
Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation
2001 Standout
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Whose end is destruction: cell division and the anaphase-promoting complex
1999
Differences and similarities between human and chimpanzee neural progenitors during cerebral cortex development
2016 StandoutNobel
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
2001 StandoutScience
Works of Tamar Listovsky being referenced
Mammalian Cdh1/Fzr mediates its own degradation
2004
Cdk1 Is Essential for Mammalian Cyclosome/APC Regulation
2000
Phosphorylation of Cdc20/Fizzy Negatively Regulates the Mammalian Cyclosome/APC in the Mitotic Checkpoint
2000 StandoutNobel
Phosphorylation of the Cyclosome Is Required for Its Stimulation by Fizzy/cdc20
1999 StandoutNobel