Standout Papers
Citation Impact
Citing Papers
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
The type III TGF-β receptor regulates epithelial and cancer cell migration through β-arrestin2-mediated activation of Cdc42
2009
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Functional specialization of β-arrestin interactions revealed by proteomic analysis
2007 StandoutNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Arresting a Transient Receptor Potential (TRP) Channel
2010 StandoutNobel
β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor
2005 StandoutNobel
β-arrestins: traffic cops of cell signaling
2004 StandoutNobel
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
2009 StandoutNobel
Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature
2007
VEGF controls endothelial-cell permeability by promoting the β-arrestin-dependent endocytosis of VE-cadherin
2006
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
β‐Arrestin2 functions as a phosphorylation‐regulated suppressor of UV‐induced NF‐κB activation
2005
Systems Biology Approach Reveals Genome to Phenome Correlation in Type 2 Diabetes
2013
TGF-β2 dictates disseminated tumour cell fate in target organs through TGF-β-RIII and p38α/β signalling
2013
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation
2006 StandoutNobel
Signaling by members of the TGF-β family in vascular morphogenesis and disease
2010
Regulation of Notch signalling by non-visual β-arrestin
2005
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Arrestins Block G Protein-coupled Receptor-mediated Apoptosis
2004
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
β‐arrestins – scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?
2009
The Arrestin Fold: Variations on a Theme
2009
Role of transforming growth factor-β superfamily signaling pathways in human disease
2008
The molecular acrobatics of arrestin activation
2004
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
GIPC Interacts with the β1-Adrenergic Receptor and Regulates β1-Adrenergic Receptor-mediated ERK Activation
2003 StandoutNobel
Dynamic Interaction between the Dual Specificity Phosphatase MKP7 and theJNK3 Scaffold Protein β-Arrestin2
2005
Emergence of the Phosphoinositide 3-Kinase-Akt- Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition
2010
Association of β-arrestin and TRAF6 negatively regulates Toll-like receptor–interleukin 1 receptor signaling
2005
Extracellular matrix structure
2015 Standout
Regulation of β-Adrenergic Receptor Signaling by S-Nitrosylation of G-Protein-Coupled Receptor Kinase 2
2007 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Emerging paradigms of β-arrestin-dependent seven transmembrane receptor signaling
2011 StandoutNobel
TGF-β signaling in vascular biology and dysfunction
2008
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2
2004 StandoutNobel
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Arrestins: ubiquitous regulators of cellular signaling pathways.
2006
The Interaction of Endoglin with β-Arrestin2 Regulates Transforming Growth Factor-β-mediated ERK Activation and Migration in Endothelial Cells
2007
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Physiologic and cardiac roles of β-arrestins
2008
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
β-arrestin-mediated receptor trafficking and signal transduction
2011 StandoutNobel
New Roles for β-Arrestins in Cell Signaling: Not Just for Seven-Transmembrane Receptors
2006 StandoutNobel
LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling
2013 StandoutNature
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
Epithelial-mesenchymal transitions: insights from development
2012
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
β-Arrestin2 Regulates the Differential Response of Cortical and Trabecular Bone to Intermittent PTH in Female Mice
2005
Smad regulation in TGF-β signal transduction
2001
β-Arrestin Deficiency Protects Against Pulmonary Fibrosis in Mice and Prevents Fibroblast Invasion of Extracellular Matrix
2011 StandoutNobel
Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes
2006 StandoutNobel
Regulation of Receptor Trafficking by GRKs and Arrestins
2006
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
β-Arrestins and Cell Signaling
2007 StandoutNobel
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
The Transforming Growth Factor-β Type III Receptor Mediates Distinct Subcellular Trafficking and Downstream Signaling of Activin-like Kinase (ALK)3 and ALK6 Receptors
2009
Signal Transduction by the TGF-β Superfamily
2002 StandoutScience
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS
2005 Standout
Endocytosis of the Type III Transforming Growth Factor-β (TGF-β) Receptor through the Clathrin-independent/Lipid Raft Pathway Regulates TGF-β Signaling and Receptor Down-regulation
2008
β-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity
2006
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex
2009 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
β-Arrestins bind and decrease cell-surface abundance of the Na + /H + exchanger NHE5 isoform
2005
Works of Tam How being referenced
The Type III Transforming Growth Factor-β Receptor as a Novel Tumor Suppressor Gene in Prostate Cancer
2007
Loss of Betaglycan Expression in Ovarian Cancer: Role in Motility and Invasion
2007
Endoglin Promotes Transforming Growth Factor β-mediated Smad 1/5/8 Signaling and Inhibits Endothelial Cell Migration through Its Association with GIPC
2008
The type III transforming growth factor- receptor negatively regulates nuclear factor kappa B signaling through its interaction with -arrestin2
2009
TβRIII suppresses non-small cell lung cancer invasiveness and tumorigenicity
2008
A Novel Mechanism for Regulating Transforming Growth Factor β (TGF-β) Signaling
2001
ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration
2009
The type III TGF-β receptor suppresses breast cancer progression
2006
Bone morphogenetic proteins induce pancreatic cancer cell invasiveness through a Smad1-dependent mechanism that involves matrix metalloproteinase-2
2008
Endocardial cell epithelial-mesenchymal transformation requires Type III TGFβ receptor interaction with GIPC
2011
The type III TGF- receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation
2007
Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion
2014
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel