Citation Impact
Citing Papers
Neurotoxic protein expression reveals connections between the circadian clock and mating behavior in Drosophila
2006 StandoutNobel
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
2005
Chaperone Suppression of α-Synuclein Toxicity in a Drosophila Model for Parkinson's Disease
2002 StandoutScience
The DNA-damage response in human biology and disease
2009 StandoutNature
Expression of Collagenase-3 (MMP-13) in Human Abdominal Aortic Aneurysms and Vascular Smooth Muscle Cells in Culture
1999
Apoptosis in the nervous system
2000 StandoutNature
The Value of Transgenic Models for the Study of Neurodegenerative Diseases
2000
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
1997 Nature
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
1997 Standout
Myotonic dystrophy, knockouts, warts
1996
Direct Interaction of Alzheimer's Disease-related Presenilin 1 with Armadillo Protein p0071
1999 StandoutNobel
Structural basis for triplet repeat disorders: a computational analysis
1999 StandoutNobel
Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
1998
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
2000
Huntington's disease
2007 Standout
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease
2007
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
2000
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
2004 StandoutNature
Intranuclear Inclusions of Expanded Polyglutamine Protein in Spinocerebellar Ataxia Type 3
1997
Abdominal aortic aneurysm
2005 Standout
The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1
1997 Nature
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Suppression of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing truncated DRPLA protein with an expanded polyglutamine stretch
1998
Pumilio1 Haploinsufficiency Leads to SCA1-like Neurodegeneration by Increasing Wild-Type Ataxin1 Levels
2015
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
2001 StandoutNature
The complex pathology of trinucleotide repeats
1997
Polyglutamine-Expanded Human Huntingtin Transgenes Induce Degeneration of Drosophila Photoreceptor Neurons
1998
Clinical and molecular advances in autosomal dominant cerebellar ataxias: from genotype to phenotype and physiopathology
2000
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Structure of the cross-β spine of amyloid-like fibrils
2005 StandoutNature
Machado‐Joseph disease gene product is a cytoplasmic protein widely expressed in brain
1997
Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice
1996 Standout
Polyglutamine Expansion Induces a Protein-damaging Stress Connecting Heat Shock Protein 70 to the JNK Pathway
2003
Molecular Genetics of Huntington’s Disease
1998
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Structural Analysis and Promoter Characterization of the Human Collagenase-3 Gene (MMP13)
1997
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
1996
TRINUCLEOTIDE REPEAT EXPANSION AND HUMAN DISEASE
1995
A Genetic Approach to Visualization of Multisynaptic Neural Pathways Using Plant Lectin Transgene
1999
Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice
2001
Transgenic models of Huntington's disease
1997
When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
1995
Expanded polyglutamine in the Machado–Joseph disease protein induces cell death in vitro and in vivo
1996
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8
2006
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Dramatic, expansion-biased, age-dependent, tissue-specific somatic mosaicism in a transgenic mouse model of triplet repeat instability
2000
A Novel Multiple PDZ Domain-containing Molecule Interacting withN-Methyl-d-aspartateReceptors and Neuronal Cell Adhesion Proteins
1998 StandoutNobel
Identification of genes that modify ataxin-1-induced neurodegeneration
2000 Nature
Spinocerebellar ataxia 3 and machado‐joseph disease: Clinical, molecular, and neuropathological features
1996
Nuclear Targeting of Mutant Huntingtin Increases Toxicity
1999
Expression analysis of the ataxin–1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals
1995
Features of trinucleotide repeat instability in vivo
2008
DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis
1997 Standout
Nucleosome Assembly on CTG Triplet Repeats
1996
Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
2005 Standout
ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc Metalloproteases
1999
Ataxin-1 Nuclear Localization and Aggregation
1998
DRPLA gene (Atrophin-1) sequence and mRNA expression in human brain
1996
Evolution and Functions of Long Noncoding RNAs
2009 Standout
The Molecular Architecture of Odor and Pheromone Sensing in Mammals
2000 StandoutNobel
A molecular pathway of neurodegeneration linking α-synuclein to ApoE and Aβ peptides
2008 StandoutNobel
The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory
2004 StandoutNobel
New order from neurological disorders
1999 Nature
Instability of highly expanded CAG repeats in mice transgenic for the Huntington's disease mutation
1997
Parkinson's Disease
2003 Standout
Expression of ataxin-2 in brains from normal individuals and patients with Alzheimer's disease and spinocerebellar ataxia 2
1999
Matrix Metalloproteinases
1999 Standout
The natural history of degenerative ataxia: a retrospective study in 466 patients
1998
Purkinje Cell Expression of a Mutant Allele ofSCA1in Transgenic Mice Leads to Disparate Effects on Motor Behaviors, Followed by a Progressive Cerebellar Dysfunction and Histological Alterations
1997
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
2003
Molecular Cloning and Structural and Functional Characterization of Human Cathepsin F, a New Cysteine Proteinase of the Papain Family with a Long Propeptide Domain
1999
SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase
2001 Standout
Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.
1996
MUTANT GENES IN FAMILIAL ALZHEIMER'S DISEASE AND TRANSGENIC MODELS
1998
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia
2001
Glutamine Repeats and Neurodegeneration
2000
Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation
1997 Standout
Mice Lacking Ataxin-1 Display Learning Deficits and Decreased Hippocampal Paired-Pulse Facilitation
1998
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Collagenase 3 Is a Target of Cbfa1, a Transcription Factor of the runt Gene Family Involved in Bone Formation
1999
Comparative sequence analysis of the human and pufferfish Huntington's disease genes
1995 StandoutNobel
Molecular Chaperones in the Cytosol: from Nascent Chain to Folded Protein
2002 StandoutScience
Neural Science
2000 StandoutNobel
Genetic Classification of Primary Neurodegenerative Disease
1998 Science
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Polyglutamine pathogenesis
1999
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Aggregation of Huntingtin in Neuronal Intranuclear Inclusions and Dystrophic Neurites in Brain
1997 StandoutScience
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Glutamine repeats and inherited neurodegenerative diseases: molecular aspects
1996
Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.
1994
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
mut-16 and other mutator class genes modulate 22G and 26G siRNA pathways in Caenorhabditis elegans
2011 StandoutNobel
Impairment of the Ubiquitin-Proteasome System by Protein Aggregation
2001 StandoutScience
A cellular model that recapitulates major pathogenic steps of Huntington's disease
1998
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of T. Matilla being referenced
SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat
1995
The human collagenase-3 (CLG3) gene is located on chromosome 11q22.3 clustered to other members of the matrix metalloproteinase gene family
1995
Clinical, neuropathologic, and genetic studies of a large spinocerebellar ataxia type 1 (SCA1) kindred
1995
Mapping of the human Zn-α<sub>2</sub>-glycoprotein gene (AZGP1) to chromosome 7q22 by in situ hybridization
1994
Molecular and clinical correlations in spinocerebellar ataxia type 3 and Machado‐Joseph disease
1995
Presymptomatic analysis of spinocerebellar ataxia type 1 (SCA1) via the expansion of the SCA1 CAG-repeat in a large pedigree displaying anticipation and parental male bias
1993