Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Protein homology model refinement by large-scale energy optimization
2018 StandoutNobel
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
A Perfluoroaryl-Cysteine S N Ar Chemistry Approach to Unprotected Peptide Stapling
2013
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV
2020 Science
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Designed protein logic to target cells with precise combinations of surface antigens
2020 StandoutScienceNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Critical assessment of methods of protein structure prediction: Progress and new directions in round XI
2016
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies
2006
How the Bcl-2 family of proteins interact to regulate apoptosis
2006
A view on drug resistance in cancer
2019 StandoutNature
Contemporary strategies for the stabilization of peptides in the α-helical conformation
2008
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Regulation of apoptosis: uncovering the binding determinants
2005
Probing the α‐Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis
2010
Determinants of BH3 Binding Specificity for Mcl-1 versus Bcl-xL
2010
A Stapled BID BH3 Helix Directly Binds and Activates BAX
2006
Autophagy regulates lipid metabolism
2009 StandoutNature
Promoting apoptosis as a strategy for cancer drug discovery
2005
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
2006
How Can Folded Biopolymers and Synthetic Foldamers Recognize Each Other?
2009
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
BCL-2 family proteins: changing partners in the dance towards death
2017
Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
2004
A Membrane-targeted BID BCL-2 Homology 3 Peptide Is Sufficient for High Potency Activation of BAX in Vitro
2006
Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor
2012 StandoutNobel
Conformational Restriction of Peptides Using Dithiol Bis-Alkylation
2016
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Voltage‐dependent anion‐selective channel (VDAC) in the plasma membrane
2010
An Electrochemically and Thermally Switchable Donor–Acceptor [c2]Daisy Chain Rotaxane
2014 StandoutNobel
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
Targeting apoptosis in cancer therapy
2020 Standout
Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices
2016
BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly
2005
Photocontrollable Peptide‐Based Switches Target the Anti‐Apoptotic Protein Bcl‐xL
2008
Direct Targeting of Rab‐GTPase–Effector Interactions
2014
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
The Future of Peptide‐based Drugs
2012 Standout
Strategies and challenges for the next generation of antibody–drug conjugates
2017 Standout
How Chemoproteomics Can Enable Drug Discovery and Development
2012
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
2005
Recent advances in magic angle spinning solid state NMR of membrane proteins
2014
Folding of β -barrel membrane proteins in lipid bilayers — Unassisted and assisted folding and insertion
2015
The Bcl-2 apoptotic switch in cancer development and therapy
2007 Standout
The Hallmarks of Aging
2013 Standout
Mitochondrial VDAC1: Function in Cell Life and Death and a Target for Cancer Therapy
2012
Life in the balance: how BH3-only proteins induce apoptosis
2005
Bispecific antibodies: a mechanistic review of the pipeline
2019
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
Protein structure determination by combining sparse NMR data with evolutionary couplings
2015
BCL2 Is a Downstream Effector of MIZ-1 Essential for Blocking c-MYC-induced Apoptosis
2006
Light‐Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin‐Mediated Endocytosis
2013
An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins
2017
Filming Biomolecular Processes by High-Speed Atomic Force Microscopy
2014
From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display
2013
Reversible Photocontrol of DNA Binding by a Designed GCN4-bZIP Protein
2006
Creating a Homeodomain with High Stability and DNA Binding Affinity by Sequence Averaging
2017
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions
2018 StandoutNobel
Bidirectional Photomodulation of Surface Tension in Langmuir Films
2016 StandoutNobel
Mimicking the Cell: Bio-Inspired Functions of Supramolecular Assemblies
2015
Supramolecular Double-Helix Formation by Diastereoisomeric Conformations of Configurationally Enantiomeric Macrocycles
2016 StandoutNobel
Function-Oriented Synthesis, Step Economy, and Drug Design
2007
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Intracellular Delivery of a Proapoptotic Peptide via Conjugation to a RAFT Synthesized Endosomolytic Polymer
2009
α/β-Peptide Foldamers Targeting Intracellular Protein–Protein Interactions with Activity in Living Cells
2015
Light‐Regulated Stapled Peptides to Inhibit Protein–Protein Interactions Involved in Clathrin‐Mediated Endocytosis
2013
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Understanding Cell Penetration of Cyclic Peptides
2019
Protein NMR Structures Refined with Rosetta Have Higher Accuracy Relative to Corresponding X-ray Crystal Structures
2014 StandoutNobel
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Towards understanding cell penetration by stapled peptides
2014
Spotlight on the Ballet of Proteins: The Structural Dynamic Properties of Proteins Illuminated by Solution NMR
2020
Macrocyclic Control in Helix Mimetics
2019
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Rotational dynamics and transition mechanisms of surface-adsorbed proteins
2022 StandoutNobel
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Engineering Biomolecular Self‐Assembly at Solid–Liquid Interfaces
2020 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomas
2005
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Modular repeat protein sculpting using rigid helical junctions
2020 StandoutNobel
Diversity-Oriented Stapling Yields Intrinsically Cell-Penetrant Inducers of Autophagy
2017
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Peptide stapling techniques based on different macrocyclisation chemistries
2014
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Rapid biocompatible macrocyclization of peptides with decafluoro-diphenylsulfone
2016
Fluorescence Correlation Spectroscopy Reveals Highly Efficient Cytosolic Delivery of Certain Penta-Arg Proteins and Stapled Peptides
2015
Constrained Peptides as Miniature Protein Structures
2012
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel
De Novo Design of Peptide−Calcite Biomineralization Systems
2010
Comparative α‐Helicity of Cyclic Pentapeptides in Water
2014
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Differential Effects of β3‐ versus β2‐Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3‐Derived α/β‐Peptides
2018
Direct control of mitochondrial function by mTOR
2009
Chemical Glycoproteomics
2016 StandoutNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Development of α-Helical Calpain Probes by Mimicking a Natural Protein–Protein Interaction
2012
Works of T. Malia being referenced
Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles
2008 Science
Design of novel FN3 domains with high stability by a consensus sequence approach
2012
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations
2013
NMR Structural Investigation of the Mitochondrial Outer Membrane Protein VDAC and Its Interaction with Antiapoptotic Bcl-xL
2006
Activation of Apoptosis in Vivo by a Hydrocarbon-Stapled BH3 Helix
2004 Science
Antibody modeling assessment II. Structures and models
2014