Citation Impact
Citing Papers
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion
1995
Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter
1995
The T Cell Leukemia Oncoprotein SCL/tal-1 Is Essential for Development of All Hematopoietic Lineages
1996
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
1996 Standout
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
2005
Partial chromosome 21 amplification in a child with acute lymphoblastic leukemia
1995
Mechanisms and impacts of chromosomal translocations in cancers
2012
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
1997 Standout
Chromosome translocations: dangerous liaisons revisited
2001
Expression of runt in the mouse embryo
1995
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
Chromatin structural elements and chromosomal translocations in leukemia
2006
Persistence of Leukemia-Initiating Cells in a Conditional Knockin Model of an Imatinib-Responsive Myeloproliferative Disorder
2009
Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation
1998
Issues in searching molecular sequence databases
1994
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
High-Resolution Profiling of Histone Methylations in the Human Genome
2007 Standout
When Checkpoints Fail
1997 StandoutNobel
Vaccinia Virus Late Transcription Is Activated in Vitro by Cellular Heterogeneous Nuclear Ribonucleoproteins
2001
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
1987 StandoutNobel
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
1997 Standout
Developmental regulation of the growth plate
2003 StandoutNature
Rasputin, more promiscuous than ever: a review of G3BP
2004
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
2003
Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain
1995
DNA Polymerase δ Is Required for Human Mismatch Repair in Vitro
1997 StandoutNobel
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
2002 Standout
Tracking and Elucidating Alphavirus-Host Protein Interactions
2006 StandoutNobel
Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
1993
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
1997 StandoutNature
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Mice Defective in Two Apoptosis Pathways in the Myeloid Lineage Develop Acute Myeloblastic Leukemia
1998
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Transcription Factors and Hematopoietic Development
1995
Mechanisms of angiogenesis
1997 StandoutNature
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Alternative splicing and genomic structure of theAML1gene involved in acute myeloid leukemia
1995
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
p63 is a p53 homologue required for limb and epidermal morphogenesis
1999 StandoutNature
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Molecular Genetic Pathways as Therapeutic Targets in Acute Myeloid Leukemia
2008
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
A new class of membrane-bound chemokine with a CX3C motif
1997 StandoutNature
Identification of human brain tumour initiating cells
2004 StandoutNature
Human DNA Damage Checkpoint Protein hRAD9 Is a 3′ to 5′ Exonuclease
2000 StandoutNobel
The CBFβ Subunit Is Essential for CBFα2 (AML1) Function In Vivo
1996
10 Years ofGenomics,Chromosome 21, and Down Syndrome
1998
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
2005 StandoutNature
Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development
2002
The cancer genome
2009 StandoutNature
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ
1987 StandoutNature
AML1 Is Expressed in Skeletal Muscle and Is Regulated by Innervation
1994
PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene.
1993
The 3;21 translocation in myelodysplasia results in a fusion transcript between the AML1 gene and the gene for EAP, a highly conserved protein associated with the Epstein-Barr virus small RNA EBER 1.
1993
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
1999 StandoutScience
Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta.
1996
Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.
1993
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia
1995
An AML1/ETO fusion transcript is consistently detected by RNA-based polymerase chain reaction in acute myelogenous leukemia containing the (8;21)(q22;q22) translocation
1993
PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.
1994
AML1/ETO-expressing nonleukemic stem cells in acute myelogenous leukemia with 8;21 chromosomal translocation
2000
Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations.
1994
Cloning and Characterization of Subunits of the T-Cell Receptor and Murine Leukemia Virus Enhancer Core-Binding Factor
1993
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Pre-replicative association of multiple replicative enzyme activities with the nuclear matrix during rat liver regeneration.
1987
Mammalian DNA ligases. Biosynthesis and intracellular localization of DNA ligase I.
1990 StandoutNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Persistence of multipotent progenitors expressing AML1/ETO transcripts in long-term remission patients with t(8;21) acute myelogenous leukemia
1996
Identification of a Region Which Directs the Monocytic Activity of the Colony-Stimulating Factor 1 (Macrophage Colony-Stimulating Factor) Receptor Promoter and Binds PEBP2/CBF (AML1)
1994
Overexpression of Core-Binding Factor α (CBFα) Reverses Cellular Transformation by the CBFβ-Smooth Muscle Myosin Heavy Chain Chimeric Oncoprotein
1995
A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator.
1996
DNA primase of human mitochondria is associated with structural RNA that is essential for enzymatic activity
1986
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
1995
Cytoplasmic Sequestration of the Polyomavirus Enhancer Binding Protein 2 (PEBP2)/Core Binding Factor α (CBFα) Subunit by the Leukemia-Related PEBP2/CBFβ-SMMHC Fusion Protein Inhibits PEBP2/CBF-Mediated Transactivation
1998
Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1).
1994
TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia
1996
The runt domain identifies a new family of heterometric transcriptional regulators
1993
AML1 is expressed in skeletal muscle and is regulated by innervation.
1994
ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex
1998
Identification of a critical regulatory site in the human interleukin-3 promoter by in vivo footprinting
1994
High frequency of t(12;21) in childhood B-lineage acute lymphoblastic leukemia
1995
Activity levels of mouse DNA polymerase alpha-primase complex (DNA replicase) and DNA polymerase alpha, free from primase activity in synchronized cells, and a comparison of their catalytic properties
1986
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Normal and leukemic hematopoiesis: Are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
2003
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia.
1994
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA.
1991
A multiprotein form of DNA polymerase alpha from HeLa cells. Resolution of its associated catalytic activities.
1986
Molecular pathogenesis of the chromosome 16 inversion in the M4Eo subtype of acute myeloid leukemia [see comments]
1995
Chromosomal translocations: revisited yet again
2008
Expression of the Runt Domain-Encoding PEBP2α Genes in T cells during Thymic Development
1995
c-Myb and Core-Binding Factor/PEBP2 Display Functional Synergy but Bind Independently to Adjacent Sites in the T-Cell Receptor δ Enhancer
1995
A unified statistical framework for sequence comparison and structure comparison
1998 StandoutNobel
GENETICS OF MYELOID LEUKEMIAS
2002
Structural and enzymological characterization of immunoaffinity-purified DNA polymerase alpha.DNA primase complex from KB cells.
1986
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Inhibition of DNA polymerase α, DNA polymerase β, terminal deoxynucleotidyl transferase, and DNA ligase II by poly(ADP-ribosyl)ation reaction in vitro
1985
The t(8;21) Fusion Protein Interferes with AML-1B-Dependent Transcriptional Activation
1995
An auxiliary protein for DNA polymerase-delta from fetal calf thymus.
1986
Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt
1992
Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.
1996
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
1991 StandoutNature
NAD(+)-dependent repair of damaged DNA by human cell extracts.
1993 StandoutNobel
Transcription Factors, Normal Myeloid Development, and Leukemia
1997
Heterogeneity in CBF beta/MYH11 fusion messages encoded by the inv(16)(p13q22) and the t(16;16)(p13;q22) in acute myelogenous leukemia
1995
Differential responses of log and stationary phase human fibroblasts to inhibition of DNA repair by aphidicolin
1982
Works of T Kozu being referenced
t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.
1991
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
1993
Mouse DNA replicase. DNA polymerase associated with a novel RNA polymerase activity to synthesize initiator RNA of strict size.
1982
Heterogeneous nuclear ribonucleoprotein B1 as a new marker of early detection for human lung cancers.
1999
Increase in dATP pool in aphidicolin-resistant mutants of mouse FM3A cells
1979
Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction
1993
Novel form of DNA polymerase alpha associated with DNA primase activity of vertebrates. Detection with mouse stimulating factor.
1983
Tight association of DNA primase with a subspecies of mouse DNA polymerase alpha.
1983
Consistent disruption of the AML1 gene occurs within a single intron in the t(8;21) chromosomal translocation.
1992