Citation Impact
Citing Papers
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help
2003 StandoutScienceNobel
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Removing T-cell epitopes with computational protein design
2014 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
CD8 + T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection
2002
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
The phenomenology and treatment of interferon-induced depression
2004
Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
2011
CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition
2010
Hepatitis B surface antigen levels: association with 5-year response to peginterferon alfa-2a in hepatitis B e-antigen-negative patients
2012
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Liver‐infiltrating and circulating CD4+ T cells in chronic hepatitis C: immunodominant epitopes, HLA‐restriction and functional significance
1996
Conserved hepatitis C virus sequences are highly immunogenic for CD4+ T cells: Implications for vaccine development
1999
Hepatitis C Virus–Specific CD4+T Cell Response after Liver Transplantation Occurs Early, Is Multispecific, Compartmentalizes to the Liver, and Does Not Correlate with Recurrent Disease
2001 StandoutNobel
Genetic variation in IL28B and spontaneous clearance of hepatitis C virus
2009 StandoutNature
Pathogenesis of hepatitis B virus infection
2010
Control of cccDNA function in hepatitis B virus infection
2009
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection
2007 Standout
Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection
2011
Hepatitis C virus core region: helper T cell epitopes recognized by BALB/c and C57BL/6 mice
1995
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.
1996 StandoutNobel
Management of viral hepatitis in patients with haematological malignancy and in patients undergoing haemopoietic stem cell transplantation: recommendations of the 5th European Conference on Infections in Leukaemia (ECIL-5)
2016
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
New insight in the pathobiology of hepatitis B virus infection
2012
Long-Term Outcome of Hepatitis C Infection after Liver Transplantation
1996
Cellular and humoral immune responses induced by intradermal or intramuscular vaccination with the major hepatitis B surface antigen
2000
Validation of a stopping rule at week 12 using HBsAg and HBV DNA for HBeAg-negative patients treated with peginterferon alfa-2a
2012
T-bet and Eomes Are Differentially Linked to the Exhausted Phenotype of CD8+ T Cells in HIV Infection
2014
Immunology of hepatitis B virus and hepatitis C virus infection
2005 Standout
Transmission of hepatitis C virus by saliva?
2005
Expression and Immune Response to Hepatitis C Virus Core Dna-Based Vaccine Constructs
1996
Extrahepatic manifestations of HCV infection: facts and controversies
1999
Hepatitis B cure: From discovery to regulatory approval
2017
Programmed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
2010
Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection
1995
T– and B–Cell Responses to Different Hepatitis C Virus Antigens in Patients With Chronic Hepatitis C Infection and in Healthy Anti– Hepatitis C Virus—Positive Blood Donors Without Viremi
1996
PD-1/PD-L1 pathway and T-cell exhaustion in chronic hepatitis virus infection
2010
Response to peginterferon alfa-2a (40KD) in HBeAg-negative CHB: On-treatment kinetics of HBsAg serum levels vary by HBV genotype
2013
Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent
2015
HBsAg seroclearance after nucleoside analogue therapy in patients with chronic hepatitis B: clinical outcomes and durability
2013
Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B.
1998
Natural and iatrogenic variation in hepatitis B virus
1999
PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients
2007
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Sources of diversity in T cell epitope discovery
2011
Characterization of Liver T–Cell Receptor γδ+ T Cells Obtained From Individuals Chronically Infected With Hepatitis C Virus (Hcv): Evidence for These T Cells Playing A Role in the Liver Pathology Associated With Hcv Infections
2001 StandoutNobel
A Jekyll and Hyde Profile: Type 1 Interferon Signaling Plays a Prominent Role in the Initiation and Maintenance of a Persistent Virus Infection
2015
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Lethal effect of the anti-Fas antibody in mice
1993 StandoutNature
Liver-Derived Hepatitis C Virus (HCV)-Specific CD4+ T Cells Recognize Multiple HCV Epitopes and Produce Interferon Gamma
2000 StandoutNobel
The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T–lymphocyte response
1996
Detection of Type 2–Like T–Helper Cells in Hepatitis C Virus Infection: Implications for Hepatitis C Virus Chronicity
1997
Pathogenesis of chronic hepatitis C: Immunological features of hepatic injury and viral persistence
1999
CD4 T Lymphocyte Proliferative Responses to Hepatitis C Virus (HCV) Antigens in Patients Coinfected with HCV and Human Immunodeficiency Virus Who Responded to Anti‐HCV Treatment
2002 StandoutNobel
Differential Cd4+ and Cd8+ T–Cell Responsiveness in Hepatitis C Virus Infection
2001
Priming of hepatitis C virus-specific cytotoxic t lymphocytes in mice following portal vein injection of a liver-specific plasmid DNA
2000 StandoutNobel
Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells
1994 Nature
T cell exhaustion during persistent viral infections
2015
Characteristics of the intrahepatic cytotoxic T lymphocyte response in chronic hepatitis C virus infection
1997
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Evolution of hepatitis B virus during primary infection in humans: Transient generation of cytotoxic T-cell mutants
2004
Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif.
1995 StandoutNobel
Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection
2012
Optimal management of hepatitis B virus infection – EASL Special Conference
2015
Induction in vitro of a primary human antiviral cytotoxic T cell response
1995 StandoutNobel
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Acute exacerbations of chronic type B hepatitis are accompanied by increased T cell responses to hepatitis B core and e antigens. Implications for hepatitis B e antigen seroconversion.
1992
Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
2009 StandoutNobel
The role of hepatitis C virus specific CD4+ T lymphocytes in acute and chronic hepatitis C
1996
Cancer immunotherapy comes of age
2011 StandoutNature
Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B
2003
Lamivudine Treatment Can Overcome Cytotoxic T–Cell Hyporesponsiveness in Chronic Hepatitis B: New Perspectives for Immune Therapy
2001
Hepatitis C Virus‐Specific Cytolytic T Lymphocyte and T Helper Cell Responses in Seronegative Persons
1997 StandoutNobel
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
2008 Standout
Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8+ T Cell Responses to Chronic Viral Infections and Cancer
2017 StandoutNobel
The Immunoregulatory Role of CD244 in Chronic Hepatitis B Infection and its Inhibitory Potential on Virus-Specific CD8+ T-cell Function
2010
Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection
2007
Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection.
1996
The role of innate immunity in the immunopathology and treatment of HBV infection
2016
The serology of chronic hepatitis B infection revisited.
1993
Hepatitis B virus (HBV) sequence variation of cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection.
1995
Adaptive immunity in HBV infection
2016
Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization
2008
Direct ex vivo analysis of hepatitis B virus-specific CD8+ T cells associated with the control of infection
1999
Inhibitory Phenotype of HBV-Specific CD4+ T-Cells Is Characterized by High PD-1 Expression but Absent Coregulation of Multiple Inhibitory Molecules
2014
Antiviral CD8-mediated responses in chronic HCV carriers with HBV superinfection
2004
Comparative features of hepatitis C virus infection in humans and chimpanzees
1997
Induction of Interleukin‐12 Production in Chronic Hepatitis C Virus Infection Correlates with the Hepatocellular Damage
1998
The molecular neurobiology of depression
2008 StandoutNature
Immunopathology of hepatitis C
1997
HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.
1995 StandoutNobel
Limited humoral immunity in hepatitis C virus infection
1999
Association of multispecific CD4+ response to hepatitis C and severity of recurrence after liver transplantation
1999 StandoutNobel
Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.
1997
Hepatitis C virus (HCV) genotype, tissue HCV antigens, hepatocellular expression of HLA-A,B,C, and intercellular adhesion-1 molecules. Clues to pathogenesis of hepatocellular damage and response to interferon treatment in patients with chronic hepatitis C.
1995
Hepatitis B Virus Biology and Pathogenesis
1992
Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B
2009
A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection
2013
Blockade of T im‐3 signaling restores the virus‐specific CD 8+T ‐cell response in patients with chronic hepatitis B
2012
Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection
2008
The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection
2000
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection
2017 Standout
Adding pegylated interferon to entecavir for hepatitis B e antigen–positive chronic hepatitis B: A multicenter randomized trial (ARES study)
2014
T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections
1994
Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade
2008
Immune evasion versus recovery after acute hepatitis C virus infection from a shared source
2005
Impaired Allostimulatory Capacity of Peripheral Blood Dendritic Cells Recovered from Hepatitis C Virus-Infected Individuals
1999
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease
2002
PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
2009
2014
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Rationally Engineered Therapeutic Proteins with Reduced Immunogenicity
2005
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Inhibitory Receptors on Lymphocytes: Insights from Infections
2012
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.
1995 StandoutNobel
Hepatitis B virus (HBV)-specific cytotoxic T-cell response in humans: production of target cells by stable expression of HBV-encoded proteins in immortalized human B-cell lines
1992
Sequential Combination Therapy with Pegylated Interferon Leads to Loss of Hepatitis B Surface Antigen and Hepatitis B e Antigen (HBeAg) Seroconversion in HBeAg-Positive Chronic Hepatitis B Patients Receiving Long-Term Entecavir Treatment
2015
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
The Outcome of Acute Hepatitis C Predicted by the Evolution of the Viral Quasispecies
2000 Science
Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection
1997 StandoutNobel
Long-Term Follow-Up of Chimpanzees Inoculated with the First Infectious Clone for Hepatitis C Virus
1999 StandoutNobel
Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection
2007
Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection
2001
Kinetics of CD4+and CD8+Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees
2003 StandoutNobel
Interleukin-2 downregulates hepatitis B virus gene expression in transgenic mice by a posttranscriptional mechanism
1993
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Prominent proliferative response of peripheral blood mononuclear cells to a recombinant non-structural (NS3) protein of hepatitis C virus in patients with chronic hepatitis C
1995
Cellular Immune Responses to the Hepatitis B Virus Polymerase
2004
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells
2015
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis.
1993
Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion
2009
Several Common HLA-DR Types Share Largely Overlapping Peptide Binding Repertoires
1998
Indispensable Role for TNF-α and IFN-γ at the Effector Phase of Liver Injury Mediated by Th1 Cells Specific to Hepatitis B Virus Surface Antigen
2000
Virus-Specific CD8+Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C
2002
HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen.
1991
Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection
2002
Effects of interferon treatment on the antiviral T-cell response in hepatitis C virus genotype 1b- and genotype 2c-infected patients
1997 StandoutNobel
Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection
1995
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis.
1995
Hypervariable Region 1 Variants Act as TCR Antagonists for Hepatitis C Virus-Specific CD4+ T Cells
1999
De novo design of protein logic gates
2020 StandoutScienceNobel
Immunobiology and Pathogenesis of Hepatocellular Injury in Hepatitis B Virus Transgenic Mice
1990 Science
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Works of T. Giuberti being referenced
Randomised study comparing 48 and 96 weeks peginterferon α-2a therapy in genotype D HBeAg-negative chronic hepatitis B
2012
The Characteristics of the Cell-Mediated Immune Response Identify Different Profiles of Occult Hepatitis B Virus Infection
2008
Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis
2012
Restored Function of HBV-Specific T Cells After Long-term Effective Therapy With Nucleos(t)ide Analogues
2012
Combined Blockade of Programmed Death-1 and Activation of CD137 Increase Responses of Human Liver T Cells Against HBV, But Not HCV
2012
Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen.
1991
Natural killer cell phenotype modulation and natural killer/T‐cell interplay in nucleos(t)ide analogue‐treated hepatitis e antigen‐negative patients with chronic hepatitis B
2015
98 EXTENDED (2 YEARS) TREATMENT WITH PEGINTERFERON ALFA-2A [40KD] IMPROVES SUSTAINED RESPONSE RATES IN GENOTYPE D PATIENTS WITH HBEAG NEGATIVE CHRONIC HEPATITIS B
2010
Selective sensitization of peripheral blood T lymphocytes to hepatitis B core antigen in patients with chronic active hepatitis type B.
1986
Cellular immune response to hepatitis B virus-encoded antigens in acute and chronic hepatitis B virus infection.
1990
Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection
2007
Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope.
1994
Intrahepatic, nucleocapsid antigen-specific T cells in chronic active hepatitis B.
1987
Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.
1991
Cytotoxic T lymphocytes recognize an HLA-A2 restricted epitope within the hepatitis B virus nucleocapsid antigen
1991
Multiple changes in thyroid function in patients with chronic active HCV hepatitis treated with recombinant interferon-alpha
1996
T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections
1994
Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response
2002