Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Alternative pathways of non-homologous end joining (NHEJ) in genomic instability and cancer
2013
Classical and Alternative End-Joining Pathways for Repair of Lymphocyte-Specific and General DNA Double-Strand Breaks
2012
The sequences of human and bovine genes of the phosphate carrier from mitochondria contain evidence of alternatively spliced forms.
1994 StandoutNobel
Within Germinal Centers, Isotype Switching of Immunoglobulin Genes Occurs after the Onset of Somatic Mutation
1996
The DNA-damage response in human biology and disease
2009 StandoutNature
Sequences of members of the human gene family for the c subunit of mitochondrial ATP synthase
1993 StandoutNobel
Immunoglobulin light chain variable region gene sequences for human antibodies to Haemophilus influenzae type b capsular polysaccharide are dominated by a limited number of V kappa and V lambda segments and VJ combinations.
1992
IMGT, the international ImMunoGeneTics database
1999
Neural network detects errors in the assignment of mRNA splice sites
1990
Cloning and sequencing of human immunoglobulin λ. gene segments
1993 StandoutNobel
Human Immunoglobulin Heavy-Chain Variable Region Genes: Organization, Polymorphism, and Expression
1991
IMGT, the international ImMunoGeneTics database
2000
Isolation of cDNA encoding a binding protein specific to 5'-phosphorylated single-stranded DNA with G-rich sequences
1993 StandoutNobel
Genetic instabilities in human cancers
1998 StandoutNature
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Understanding the recent evolution of the human genome: insights from human-chimpanzee genome comparisons
2006
High Frequency Targeted Mutagenesis Using Engineered Endonucleases and DNA-End Processing Enzymes
2013
Genetic Differences between Humans and Great Apes
2001
Tracking genome engineering outcome at individual DNA breakpoints
2011
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
Biology of the Human γ T‐Cell Receptor
1991
Induction of interferon‐α production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
2004
Human T-cell receptor variable gene segment families
1995
Repair of Strand Breaks by Homologous Recombination
2013
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
The membrane exons of the pseudo-γ-chain gene of the human immunoglobulin are apparently functional and highly homologous to those of the γ1 gene
1991
Molecular analysis of human immunoglobulin Vλ germline genes: Subgroups VλIII and VλIV
1992
MMEJ repair of double-strand breaks (director’s cut): deleted sequences and alternative endings
2008
Combinatorial infection andin vivorecombination: a strategy for making large phage antibody repertoires
1993 StandoutNobel
Initial sequence of the chimpanzee genome and comparison with the human genome
2005 StandoutNature
Molecular characterization of the human immunoglobulin VλI germline gene repertoire
1992
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
IgH class switching and translocations use a robust non-classical end-joining pathway
2007 Nature
Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences
2001
Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
1992 StandoutNobel
Evidence implicating heterozygous deletion of chromosome 7 in the pathogenesis of familial leukemia associated with monosomy 7
1992
Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups
1990
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito
2011 StandoutNatureNobel
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Vλ and Jλ‐Cλ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism
1991
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Toll‐like receptors, endogenous ligands, and systemic autoimmune disease
2005
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Meganucleases and Other Tools for Targeted Genome Engineering: Perspectives and Challenges for Gene Therapy
2011
Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?
2015
Genomic sequence of IGLV1S2, a human immunoglobulin variable lambda gene belonging to subgroup I
1990
Proteomic comparison of human and great ape blood plasma reveals conserved glycosylation and differences in thyroid hormone metabolism
2001
Physical Maps of the Mouse and Human Immunoglobulin-like Loci
1989
The Human Condition—A Molecular Approach
2014 StandoutNobel
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
A multigene deletion in the human IGH constant region locus involves highly homologous hot spots of recombination
1989
Sequencing the chimpanzee genome: insights into human evolution and disease
2002
The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor
1989
Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70
2010
Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain
1989 Science
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.
1988
Extensive Junctional Diversity of Rearranged Human T Cell Receptor δ Genes
1988 Science
Mechanisms of double-strand break repair in somatic mammalian cells
2009
A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
2001 StandoutNobel
Recognition of Stress-Induced MHC Molecules by Intestinal Epithelial γδ T Cells
1998 StandoutScience
CD45: A Critical Regulator of Signaling Thresholds in Immune Cells
2003
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
The rate of telomere sequence loss in human leukocytes varies with age
1998 StandoutNobel
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease
2009
Bovine papillomavirus transcriptional regulation: localization of the E2-responsive elements of the long control region
1987
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
Modulating DNA Repair Pathways to Improve Precision Genome Engineering
2017
Progressive engineering of a homing endonuclease genome editing reagent for the murine X-linked immunodeficiency locus
2014 StandoutNobel
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1995 Standout
Intra- and Interspecific Variation in Primate Gene Expression Patterns
2002 StandoutScienceNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
T Cell Receptor Gene Trans-Rearrangements: Chimeric γ-δ Genes in Normal Lymphoid Tissues
1989 Science
Duplicated variable region genes account for double isotype expression in a human leukemic B-cell line that gives rise to single isotype-expressing cells
1991 StandoutNobel
Neural Computing in Cancer Drug Development: Predicting Mechanism of Action
1992 StandoutScienceNobel
Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task
2000 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.
1987
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.
1989 StandoutNobel
Human anti-self antibodies with high specificity from phage display libraries.
1993
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Mismatch Repair Proteins MSH2, MLH1, and EXO1 Are Important for Class-Switch Recombination Events Occurring in B Cells That Lack Nonhomologous End Joining
2011
Works of Sylvie Huck being referenced
First nucleotide sequence of a human immunoglobulin variable λ gene belonging to subgroup II
1989
A human immunoglobulinIGHG3 allele (Gmb0, b1, c3, c5, u) with anIGHG4 converted region and three hinge exons
1989
S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining
2007
Restriction fragment haplotypes in the human immunoglobulin IGHG locus and their correlation with the Gm polymorphism
1988
The human immunoglobulin pseudo-gamma IGHGP gene shows no major structural defect
1988
Rearrangements to the JP1, JP and JP2 segments in the human T‐cell rearranging gamma gene (TRGγ) locus
1987
T cell receptor γ cDNA in human fetal liver and thymus: Variable regions of γ chains are restricted to VγI or V9, due to the absence of splicing of the V10 and V11 leader intron
1994
Analysis of intrachromosomal homologous recombination in mammalian cell, using tandem repeat sequences
1999
The human T-cell receptor gamma variable pseudogeneV10 is a distinctive marker of human speciation
1996
Impact of the KU80 Pathway on NHEJ-Induced Genome Rearrangements in Mammalian Cells
2004
Abnormal DNA methylation and deoxycytosine‐deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis
1999
Expression of B Cell Receptor-Associated Signaling Molecules in Human Lupus
2001
Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes.
1988
A gamma 3 hinge region probe: first specific human immunoglobulin subclass probe
1986
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human Cγgenes
1986
New subgroups in the human T cell rearranging V gamma gene locus.
1987
Exon duplication and triplication in the human T-cell receptor gamma constant region genes and RFLP in French, Lebanese, Tunisian, and Black African populations
1989