Standout Papers
Citation Impact
Citing Papers
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Poly(ADP-ribose)–Dependent Regulation of DNA Repair by the Chromatin Remodeling Enzyme ALC1
2009 Science
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin
2006 StandoutNobel
Tissue specificity and the human protein interaction network
2009
In silico prediction of protein-protein interactions in human macrophages
2014 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
The RNA-binding Protein Fused in Sarcoma (FUS) Functions Downstream of Poly(ADP-ribose) Polymerase (PARP) in Response to DNA Damage
2013
Human RNA Methyltransferase BCDIN3D Regulates MicroRNA Processing
2012
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Procaspase-3 and Poly(ADP)ribose Polymerase (PARP) Are Calpain Substrates
1999
Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells
2009
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Chromatin Modifications and Their Function
2007 Standout
Regulation of microRNA biogenesis
2014 Standout
Calpain and caspase: can you tell the difference?
2000 Standout
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
2001 StandoutNature
Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
2000
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Neocentromeres: Role in Human Disease, Evolution, and Centromere Study
2002
Peptide dendrimers: applications and synthesis
2002
Apoptosis is Initiated by Myocardial Ischemia and Executed During Reperfusion
2000
Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death
2011
Loss of OPA1 Perturbates the Mitochondrial Inner Membrane Structure and Integrity, Leading to Cytochrome c Release and Apoptosis
2003
Histone variants: deviants?
2005
Cell Death
2004 Standout
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1
2010
Mitochondria: In Sickness and in Health
2012 Standout
Network organization of the human autophagy system
2010 StandoutNature
Ikaros-Family Proteins: In Search of Molecular Functions During Lymphocyte Development
2005
Human Corneal Thickness and Its Impact on Intraocular Pressure Measures
2000 Standout
Pause locally, splice globally
2011
Granzyme Release and Caspase Activation in Activated Human T-Lymphocytes
1998
Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31
1999
The diverse roles and clinical relevance of PARPs in DNA damage repair: Current state of the art
2012
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Plant pathogens and integrated defence responses to infection
2001 StandoutNature
Importance of Poly(ADP-Ribose) Glycohydrolase in the Control of Poly(ADP-Ribose) Metabolism
2001
Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm
2011
PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain
2015
The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders
2002
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation
2009
Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4
2010
The Role of Chromatin during Transcription
2007 Standout
Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres
1997
Cleavage of Automodified Poly(ADP-ribose) Polymerase during Apoptosis
1999
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Defining the Human Deubiquitinating Enzyme Interaction Landscape
2009
Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes
2010
Centromere DNA, proteins and kinetochore assembly in vertebrate cells
2004
Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila
2011 StandoutNobel
Regulation of chromatin structure by site-specific histone H3 methyltransferases
2000 StandoutNature
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
Poly(ADP-ribose) signals to mitochondrial AIF: A key event in parthanatos
2009
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
2001 StandoutNature
SGT1 Encodes an Essential Component of the Yeast Kinetochore Assembly Pathway and a Novel Subunit of the SCF Ubiquitin Ligase Complex
1999
The BCL-2 protein family: opposing activities that mediate cell death
2007 Standout
Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death
2004
PARP inhibition: PARP1 and beyond
2010
Integration-Free iPS Cells Engineered Using Human Artificial Chromosome Vectors
2011 StandoutNobel
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
2018 Nature
The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives
2006
Learning How to Read ADP-Ribosylation
2009
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Human poly(ADP-ribose) glycohydrolase is expressed in alternative splice variants yielding isoforms that localize to different cell compartments
2004
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
The map-based sequence of the rice genome
2005 StandoutNature
NMDA But Not Non-NMDA Excitotoxicity is Mediated by Poly(ADP-Ribose) Polymerase
2000
Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality
2004
Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination
2009
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage
2011
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
2011
Interaction between Poly(ADP-ribose) and NuMA Contributes to Mitotic Spindle Pole Assembly
2009
Apoptosis: A Review of Programmed Cell Death
2007 Standout
A RECQ5–RNA polymerase II association identified by targeted proteomic analysis of human chromatin
2008
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
Functional Rice Centromeres Are Marked by a Satellite Repeat and a Centromere-Specific Retrotransposon
2002
Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions
1999 Standout
Poly(ADP-ribose) (PAR) polymer is a death signal
2006 Standout
Human Artificial Chromosomes with Alpha Satellite-Based De Novo Centromeres Show Increased Frequency of Nondisjunction and Anaphase Lag
2003
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Poly(ADP-Ribose) (PAR) Binding to Apoptosis-Inducing Factor Is Critical for PAR Polymerase-1–Dependent Cell Death (Parthanatos)
2011
Structural Dynamics of Eukaryotic Chromosome Evolution
2003 StandoutScience
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Identification of three critical acidic residues of poly(ADP-ribose) glycohydrolase involved in catalysis: determining the PARG catalytic domain
2005
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
2000 StandoutNobel
Expression of Helios in Peripherally Induced Foxp3+ Regulatory T Cells
2011 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Works of Sylvie Bourassa being referenced
Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly(ADP-ribose) polymerase
1997
Systematic Analysis of the Protein Interaction Network for the Human Transcription Machinery Reveals the Identity of the 7SK Capping Enzyme
2007
Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres
1997
Immunodot Blot Method for the Detection of Poly(ADP-ribose) Synthesizedin Vitroandin Vivo
1998
Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo
1999
Poly(ADP-ribose) Glycohydrolase Is Present and Active in Mammalian Cells as a 110-kDa Protein
1999
Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
2008
Preferential Perinuclear Localization of Poly(ADP-ribose) Glycohydrolase
1999
Effect of humidity on the deswelling function of the human cornea
1991
A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells
2016 StandoutNobel
Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs
2015
Proteomic Investigation of Phosphorylation Sites in Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase
2008
Characterization of antibodies specific for the caspase cleavage site on poly(ADP-ribose)polymerase: specific detection of apoptotic fragments and mapping of the necrotic fragments of poly(ADP-ribose)polymerase
1997