Citation Impact
Citing Papers
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Quantitative analysis of the expression of ACAT genes in human tissues by real-time PCR2
2004
A critical role of VMP1 in lipoprotein secretion
2019
Differential expression of ACAT1 and ACAT2 among cells within liver, intestine, kidney, and adrenal of nonhuman primates
2000
Identification of ACAT1- and ACAT2-specific inhibitors using a novel, cell-based fluorescence assay
2004 StandoutNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Sixteen hours of fasting differentially affects hepatic and muscle insulin sensitivity in mice
2004
Identification of the Interaction Site within Acyl-CoA:Cholesterol Acyltransferase 2 for the Isoform-specific Inhibitor Pyripyropene A
2008 StandoutNobel
Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice
2013
Medicinal strategies in the treatment of obesity
2000 Nature
Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease
2013
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
2007
The Enzymes of Neutral Lipid Synthesis
2001
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5)
2006 StandoutNobel
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Characterization of Two Human Genes Encoding Acyl Coenzyme A:Cholesterol Acyltransferase-related Enzymes
1998
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
A Novel Nociceptor Signaling Pathway Revealed in Protein Kinase C ε Mutant Mice
1999
Absence of ACAT-1 Attenuates Atherosclerosis but Causes Dry Eye and Cutaneous Xanthomatosis in Mice with Congenital Hyperlipidemia
2000
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance
2010
Roles of acyl-coenzyme A : cholesterol acyltransferase-1 and -2
2001
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
Dissociating fatty liver and diabetes
2012
The multifaceted roles of fatty acid synthesis in cancer
2016
Variation in the safety of induced pluripotent stem cell lines
2009 StandoutNobel
Human Acyl-CoA:Cholesterol Acyltransferase-1 Is a Homotetrameric Enzyme in Intact Cells and in Vitro
1999
Primates Highly Responsive to Dietary Cholesterol Up-regulate Hepatic ACAT2, and Less Responsive Primates Do Not
2002
Differential Roles for Sox15 and Sox2 in Transcriptional Control in Mouse Embryonic Stem Cells
2005 StandoutNobel
Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine
2000
Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway
2000 StandoutNobel
The Endoplasmic Reticulum Enzyme DGAT2 Is Found in Mitochondria-associated Membranes and Has a Mitochondrial Targeting Signal That Promotes Its Association with Mitochondria
2008
Monounsaturated Fatty Acid Modification of Wnt Protein: Its Role in Wnt Secretion
2006
Suppression of Diacylglycerol Acyltransferase-2 (DGAT2), but Not DGAT1, with Antisense Oligonucleotides Reverses Diet-induced Hepatic Steatosis and Insulin Resistance
2007
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.
1997
3 ACAT Inhibitors: The Search for a Novel and Effective Treatment of Hypercholesterolemia and Atherosclerosis
2002
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1
2000
Mammalian acyl-CoA:cholesterol acyltransferases
2000
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
2005
Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis
2014
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis
2017
Atherosclerosis — An Inflammatory Disease
1999 Standout
Human Acyl-CoA:Cholesterol Acyltransferase-1 in the Endoplasmic Reticulum Contains Seven Transmembrane Domains
1999
Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle
2007
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages
2001
A Fresh Look at iPS Cells
2009 StandoutNobel
ECAT11/L1td1 Is Enriched in ESCs and Rapidly Activated During iPSCGeneration, but It Is Dispensable for the Maintenance and Induction of Pluripotency
2011 StandoutNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Obesity and the Regulation of Energy Balance
2001 Standout
The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosis
2011
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling
2012
A genetically humanized mouse model for hepatitis C virus infection
2011 StandoutNatureNobel
Identification, Cloning, Expression, and Purification of Three Novel Human Calcium-independent Phospholipase A2 Family Members Possessing Triacylglycerol Lipase and Acylglycerol Transacylase Activities
2004
Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice
2000
Lipid-Induced Mitochondrial Stress and Insulin Action in Muscle
2012
Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy
2009
Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts
2009 StandoutNobel
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
2012
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
2015
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Molecular mechanisms of apolipoprotein B mRNA editing
2001
Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice
2000
Identification of a Form of Acyl-CoA:Cholesterol Acyltransferase Specific to Liver and Intestine in Nonhuman Primates
1998
Suppression of induced pluripotent stem cell generation by the p53–p21 pathway
2009 StandoutNatureNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Using mouse models to dissect the genetics of obesity
2002
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase
2006 Science
Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice
2003
mTOR Is Essential for Growth and Proliferation in Early Mouse Embryos and Embryonic Stem Cells
2004 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
ACAT1 and ACAT2 Membrane Topology Segregates a Serine Residue Essential for Activity to Opposite Sides of the Endoplasmic Reticulum Membrane
2000
Upregulation of myocellular DGAT1 augments triglyceride synthesis in skeletal muscle and protects against fat-induced insulin resistance
2007
Nuclear receptor PPARγ-regulated monoacylglycerol O -acyltransferase 1 (MGAT1) expression is responsible for the lipid accumulation in diet-induced hepatic steatosis
2012
Reactivation of the Paternal X Chromosome in Early Mouse Embryos
2004 StandoutScienceNobel
Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis
2004 StandoutNobel
ACAT2 Is Localized to Hepatocytes and Is the Major Cholesterol-Esterifying Enzyme in Human Liver
2004 StandoutNobel
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Disordered Fat Storage and Mobilization in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
2002
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism
1997
Plasma Cholesteryl Esters Provided by Lecithin:Cholesterol Acyltransferase and Acyl-Coenzyme A:Cholesterol Acyltransferase 2 Have Opposite Atherosclerotic Potential
2004
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Fbx15 Is a Novel Target of Oct3/4 but Is Dispensable for Embryonic Stem Cell Self-Renewal and Mouse Development
2003 StandoutNobel
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
ACAT2 Is a Target for Treatment of Coronary Heart Disease Associated With Hypercholesterolemia
2005
Human Acyl-Coenzyme A:Cholesterol Acyltransferase Expressed in Chinese Hamster Ovary Cells: Membrane Topology and Active Site Location
2003
Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
2014
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans
2011
Acyl coenzyme A : cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis
2001
Works of Sylvaine Cases being referenced
Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase
2000
Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat
2000
Cloning of DGAT2, a Second Mammalian Diacylglycerol Acyltransferase, and Related Family Members
2001
ACAT-2, A Second Mammalian Acyl-CoA:Cholesterol Acyltransferase
1998
Adrenocortical Lipid Depletion Gene (ald) in AKR Mice Is Associated with an Acyl-CoA:Cholesterol Acyltransferase (ACAT) Mutation
1998
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: Evidence suggesting multiple cholesterol esterification enzymes in mammals
1996
A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice
1996
Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis
1998
Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase
2002
LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA)
2007
Triglyceride accumulation protects against fatty acid-induced lipotoxicity
2003 Standout