Citation Impact
Citing Papers
Anchored periplasmic expression, a versatile technology for the isolation of high-affinity antibodies from Escherichia coli -expressed libraries
2004
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Structure of the 70 S Ribosome Complexed with mRNA and tRNA
2006 StandoutScienceNobel
Structures of the CRISPR genome integration complex
2017 StandoutScienceNobel
An Extensive Class of Small RNAs in Caenorhabditis elegans
2001 StandoutScienceNobel
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
2001 StandoutNobel
How Initiation Factors Maximize the Accuracy of tRNA Selection in Initiation of Bacterial Protein Synthesis
2006
Interaction of Translation Initiation Factor 3 with the 30S Ribosomal Subunit
2001
Initiation factor eIF2γ promotes eIF2–GTP–Met-tRNAiMet ternary complex binding to the 40S ribosome
2011
Solution Structure of the E. coli 70S Ribosome at 11.5 Å Resolution
2000 StandoutNobel
Identification of an expanded set of translationally active methionine analogues in Escherichia coli
2001
Solution Structure of Human Initiation Factor eIF2α Reveals Homology to the Elongation Factor eEF1B
2004
Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3
2001
Translation initiation factor IF3: two domains, five functions, one mechanism?
2001
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors
2002
Functional proteins from a random-sequence library
2001 StandoutNatureNobel
Translation initiation: structures, mechanisms and evolution
2004
Structure of the 30S ribosomal subunit
2000 StandoutNatureNobel
Crystal structure and mechanism of a calcium-gated potassium channel
2002 StandoutNatureNobel
Roles of yeast eIF2α and eIF2β subunits in the binding of the initiator methionyl-tRNA
2012
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
The structure of the translational initiation factor IF1 from E.coli contains an oligomer-binding motif
1997
MUSCLE: multiple sequence alignment with high accuracy and high throughput
2004 Standout
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli
2011
Structure of a bacterial 30S ribosomal subunit at 5.5 Å resolution
1999 StandoutNatureNobel
The mechanism of eukaryotic translation initiation and principles of its regulation
2010 Standout
‘Ribozoomin’ – Translation Initiation from the Perspective of the Ribosome-bound Eukaryotic Initiation Factors (eIFs)
2012
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Structural studies of protein–nucleic acid interaction: the sources of sequence-specific binding
1990 StandoutNobel
NAD+ binding to the Escherichia coli K+‐uptake protein TrkA and sequence similarity between TrkA and domains of a family of dehydrogenases suggest a role for NAD+ in bacterial transport
1993
Identification of an amino acid region supporting specific methionyl-tRNA synthetase: tRNA recognition
1989
Enzyme promiscuity: evolutionary and mechanistic aspects
2006
Initiation factors of protein biosynthesis in bacteria and their structural relationship to elongation and termination factors
1998
Chemical remodelling of cell surfaces in living animals
2004 StandoutNatureNobel
Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs
1990 Nature
The structure of the E. coli recA protein monomer and polymer
1992 StandoutNatureNobel
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
Structure of the ternary initiation complex aIF2–GDPNP–methionylated initiator tRNA
2012
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
The fidelity of translation initiation: reciprocal activities of eIF1, IF3 and YciH
2005
How methionyl-tRNA synthetase creates its amino acid recognition pocket upon l-methionine binding
2001
Improved protein structure prediction using potentials from deep learning
2020 StandoutNatureNobel
Escherichia coli initiation factor 3 protein binding to 30S ribosomal subunits alters the accessibility of nucleotides within the conserved central region of 16S rRNA
1989
Structure-function analysis of Escherichia coli translation initiation factor IF3: tyrosine 107 and lysine 110 are required for ribosome binding
1992
Structure of tyrosyl-tRNA synthetase refined at 2.3 Å resolution
1989
Efficient introduction of alkene functionality into proteins in vivo
1998
Interaction of translation initiation factor IF1 with the E. coli ribosomal A site
2000
Hypermutagenic PCR Involving All Four Transitions and a Sizeable Proportion of Transversions
1996
Crystal Structure of the Intact Archaeal Translation Initiation Factor 2 Demonstrates Very High Conformational Flexibility in the α- and β-Subunits
2008
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Crystallographic study at 2·5 Å resolution of the interaction of methionyl-tRNA synthetase from Escherichia coli with ATP
1990
Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase
1991 StandoutNatureNobel
Crystal structure of the ribosome recycling factor bound to the ribosome
2007 StandoutNobel
Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex
2006
Structural and functional implications in the eubacterial ribosome as revealed by protein–rRNA and antibiotic contact sites
1995
Ribosome Structure and the Mechanism of Translation
2002 StandoutNobel
Dissection of the structure and activity of the tyrosyl-tRNA synthetase by site-directed mutagenesis
1987
Cotranslational Incorporation of a Structurally Diverse Series of Proline Analogues in an Escherichia coli Expression System
2004
Analysis of one million base pairs of Neanderthal DNA
2006 StandoutNatureNobel
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
2001 StandoutNatureNobel
Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29
2013 StandoutNobel
Evolution of protein function by Domain swapping
2001
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Demonstration of two reaction pathways for the aminoacylation of tRNA. Application of the pulsed quenched flow technique
1975
Structural insights on the translation initiation complex: ghosts of a universal initiation complex
2006 StandoutNobel
Construction of heterodimer tyrosyl-tRNA synthetase shows tRNATyr interacts with both subunits.
1986 StandoutNobel
Expanding the Scope of Protein Biosynthesis by Altering the Methionyl-tRNA Synthetase Activity of a Bacterial Expression Host
2000
Molecular Mechanism of Scanning and Start Codon Selection in Eukaryotes
2011
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
2000 StandoutScienceNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution
1985 StandoutScienceNobel
Formylmethionyl-tRNA binding to 30 S ribosomes programmed with homopolynucleotides and the effect of translational initiation factor 3
1986
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
The allosteric three-site model for the ribosomal elongation cycle
1989
Characterization of a Novel Yeast SNARE Protein Implicated in Golgi Retrograde Traffic
1997
Crystal Structure of an Initiation Factor Bound to the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding
1982 StandoutNatureNobel
Cell Surface Engineering by a Modified Staudinger Reaction
2000 StandoutScienceNobel
Efficient Incorporation of Unsaturated Methionine Analogues into Proteins in Vivo
2000
X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.
1995 StandoutNobel
Active site titration and aminoacyl adenylate binding stoichiometry of aminoacyl-tRNA synthetases
1975
Structure classification-based assessment of CASP3 predictions for the fold recognition targets
1999
Quality Control Mechanisms During Translation
1999 Science
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids
2006 StandoutNobel
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles
1983
Exploring the possibilities presented by protein engineering
2000
Cross-linking of initiation factor IF3 toEscherichia coli30S ribosomal subunit by trans-dlamminedichloroplatinum(II): characterization of two cross-linking sites in 16S rRNA; a possible way of functioning for IF3
1986
Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
2003 StandoutScienceNobel
Fast and accurate short read alignment with Burrows–Wheeler transform
2009 Standout
Transition state stabilization by a phylogenetically conserved tyrosine residue in methionyl-tRNA synthetase.
1991
Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity
1974 StandoutNobel
Conserved cysteine and histidine residues in the structures of the tyrosyl and methionyl‐tRNA synthetases
1982 StandoutNobel
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Protein Structure Prediction and Structural Genomics
2001 StandoutScienceNobel
Structural homology in the amino-terminal domains of two aminoacyl-tRNA synthetases
1983
Domains of initiator tRNA and initiation codon crucial for initiator tRNA selection by Escherichia coli IF3.
1990
The Complete Genome Sequence of Escherichia coli K-12
1997 StandoutScience
Evidence for the double-sieve editing mechanism in protein synthesis. Steric exclusion of isoleucine by valyl-tRNA synthetases
1979
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
1H and 15N Resonance Assignments and Structure of the N-Terminal Domain of Escherichia coli Initiation Factor 3
1995
Crystal structure of Escherichia coli methionyl-tRNA synthetase at 2.5 Å resolution
1982
Potential Metal-Binding Domains in Nucleic Acid Binding Proteins
1986 Science
Enzyme hyperspecificity. Rejection of threonine by the valyl-tRNA synthetase by misacylation and hydrolytic editing
1976
Structure of E. coli Glutaminyl-tRNA Synthetase Complexed with tRNA Gln and ATP at 2.8 Å Resolution
1989 StandoutScienceNobel
Evidence for Dispensable Sequences Inserted into a Nucleotide Fold
1987 Science
Location of translational initiation factor IF3 on the small ribosomal subunit
1999 StandoutNobel
β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function
1990 StandoutScienceNobel
Hydrogen bonding and biological specificity analysed by protein engineering
1985 StandoutNatureNobel
tRNA dynamics on the ribosome during translation
2004 Nobel
Kinetic amplification of enzyme discrimination
1975
Site-directed mutagenesis as a probe of enzyme structure and catalysis: tyrosyl-tRNA synthetase cysteine-35 to glycine-35 mutation
1983 StandoutNobel
Binding of tyrosine, adenosine triphosphate and analogues to crystalline tyrosyl transfer RNA synthetase
1978
Analysis of Enzyme Structure and Activity by Protein Engineering
1984 StandoutNobel
Works of Sylvain Blanquet being referenced
Maturation of Pre-tRNAfMet by Escherichia coli RNase P Is Specified by a Guanosine of the 5′-Flanking Sequence
1995
DNA binding specificities ofEscherichia coliCas1–Cas2 integrase drive its recruitment at the CRISPR locus
2016
Two Acidic Residues of Escherichia coli Methionyl-tRNA Synthetase Act as Negative Discriminants Towards the Binding of Non-cognate tRNA Anticodons
1993
Crystallization and preliminary X-ray analysis ofEscherichia colimethionyl-tRNAMetfformyltransferase complexed with formyl-methionyl-tRNAMetf
1999
Use of Analogues of Methionine and Methionyl Adenylate to Sample Conformational Changes During Catalysis in Escherichia coli Methionyl-tRNA Synthetase
2003
Methionyl-tRNA Synthetase Zinc Binding Domain
1993
Solution Structure of the Ribosome-binding Domain ofE. coliTranslation Initiation Factor IF3. Homology with the U1A Protein of the Eukaryotic Spliceosome
1995
General Structure/Function Properties of Microbial Methionyl‐Trna Synthetases
1997
Protection-Based Assays to Measure Aminoacyl-tRNA Binding to Translation Initiation Factors
2007
Molecular recognition governing the initiation of translation in Escherichia coli. A review
1996
Heteronuclear NMR studies of E. coli translation initiation factor IF3. evidence that the inter-domain region is disordered in solution 1 1 Edited by K. Nagai
1997
Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features
1999
Functional Molecular Mapping of Archaeal Translation Initiation Factor 2
2004
Functional Characterization of thed-Tyr-tRNATyr Deacylase from Escherichia coli
1999
Transition state stabilization by the ‘high’ motif of class I aminoacyl-tRNA synthetases: the case ofEscherichia colimethionyl-tRNA synthetase
1995
Discrimination by Escherichia coli initiation factor IF3 against initiation on non-canonical codons relies on complementarity rules
1999
Direct Random Mutagenesis of Gene-Sized DNA Fragments Using Polymerase Chain Reaction
1995
Crystal structure of methionyl-tRNAfMet transformylase complexed with the initiator formyl-methionyl-tRNAfMet
1998
The many routes of bacterial transfer RNAs after aminoacylation
2000
Lysine 335, part of the KMSKS signature sequence, plays a crucial role in the amino acid activation catalysed by the methionyl-tRNA synthetase from Escherichia coli
1991
Mapping of the Zinc Binding Domain of Escherichia coli Methionyl-tRNA Synthetase
1993
Identification of residues involved in the binding of methionine byEscherichia coli methionyl‐tRNA synthetase
1991
Disruption of the gene for Met-tRNA(fMet) formyltransferase severely impairs growth of Escherichia coli
1992
Neutron scattering studies of Escherichia coli tyrosyl-tRNA synthetase and of its interaction with tRNATyr
1982
Enzymatic Deacylation of Methionyl‐tRNAfMef Catalysed by Methionyl, Isoleucyl and Phenylalanyl‐tRNA Synthetases
1974
Methionyl‐Transfer‐RNA Transformylase from Escherichia coli
1980
Methionyl-tRNA synthetase from Escherichia coli: primary structure at the binding site for the 3'-end of tRNAfMet
1985
The Mechanism of Action of Methionyl-tRNA Synthetase from Escherichia coli. Inhibition by Adenosine and 8-Aminoadenosine of the Amino-Acid Activation Reaction
1975
Methionyl-tRNA synthetase from Escherichia coli: active stoichiometry and stopped-flow analysis of methionyl adenylate formation
1976
The Mechanism of Reaction of Methionyl‐tRNA Synthetase from Escherichia coli
1972
Antico-operative binding of bacterial and mammalian initiator tRNAMet to methionyl-tRNA synthetase from Escherichia coli
1976
Removal of the Tightly Bound Zinc from Escherichia coli Trypsin-Modified Methionyl-tRNA Synthetase
2005
The Mechanism of Action of Methionyl‐tRNA Synthetase from Escherichia coli
1973
Sequence similarities among the family of aminoacyl-tRNA synthetases
1986
The Mechanism of Action of Methionyl‐tRNA Synthetase
1973
Structure of crystalline Escherichia coli methionyl-tRNA(f)Met formyltransferase: comparison with glycinamide ribonucleotide formyltransferase.
1996
Expression of the Gene for Escherichia coli Initiation Factor IF‐3 in vivo and in vitro
1982
Proteolytic cleavage of methionyl transfer ribonucleic acid synthetase from Bacillus stearothermophilus: effects on activity and structure
1980
1H and 15N Resonance Assignments and Structure of the N-Terminal Domain of Escherichia coli Initiation Factor 3
1995
Isolation, characterization, and inactivation of the APA1 gene encoding yeast diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase
1989
Couplings between the sites for methionine and adenosine 5'-triphosphate in the amino acid activation reaction catalyzed by trypsin-modified methionyl-transfer RNA synthetase from Escherichia coli
1977
Extent of N-terminal methionine excision from Escherichia coli proteins is governed by the side-chain length of the penultimate amino acid.
1989
Molecular cloning and primary structure of the Escherichia coli methionyl-tRNA synthetase gene
1984
Structure−Function Relationships of the Intact aIF2α Subunit from the Archaeon Pyrococcus abyssi,
2005
Binding of zinc to Escherichia coli phenylalanyl-tRNA synthetase. Comparison with other aminoacyl-tRNA synthetases
1981
Structure-activity relationships of methionyl-tRNA synthetase: graphics modelling and genetic engineering
1987
The Mechanism of Action of Methionyl-tRNA Synthetase from Escherichia coli. Mechanism of the Amino-Acid Activation Reaction Catalyzed by the Native and the Trypsin-Modified Enzymes
1974
Neutron-scattering studies of the binding of initiator tRNAMet to Escherichia coli trypsin-modified methionyl-tRNA synthetase
1982
The amino acid activation reaction catalyzed by methionyl-transfer RNA synthetase: Evidence for synergistic coupling between the sites for methionine adenosine and pyrophosphate
1975
Homology of IysS and IysU , the two Escherichia coli genes encoding distinct Iysyl-tRNA synthetase species
1990
Sequence of a 1.26-kb DNA fragment containing the structural gene for E.coli initiation factor IF3: presence of an AUU initiator codon.
1982
Selection of suppressor methionyl-tRNA synthetases: mapping the tRNA anticodon binding site.
1991
Antico-operative binding of initiator transfer RNAMet to methionyl-transfer RNA synthetase from Escherichia coli: Neutron scattering studies
1978
Initiator tRNA Binding by e/aIF5B, the Eukaryotic/Archaeal Homologue of Bacterial Initiation Factor IF2
2005
Receptor Site for the 5‘-Phosphate of Elongator tRNAs Governs Substrate Selection by Peptidyl-tRNA Hydrolase
1999
Zinc-dependent synthesis of 5',5'-diadenosine tetraphosphate by sheep liver lysyl- and phenylalanyl-tRNA synthetases.
1982
Structure of an archaeal heterotrimeric initiation factor 2 reveals a nucleotide state between the GTP and the GDP states
2007
The Mechanism of Action of Methionyl‐tRNA Synthetase
1973
E. coli tyrosyl- and methionyl-tRNA synthetases display sequence similarity at the binding site for the 3'-end of tRNA
1986