Sylvain Bellier

Transcription–replication conflicts underlie sensitivity to PARP inhibitors

Genome organization around nuclear speckles drives mRNA splicing efficiency

Inhibitors of transcription such as 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole and isoquinoline sulfonamide derivatives (H-8 and H-7) promote dephosphorylation of the carboxyl-terminal domain of RNA polymerase II largest subunit.