Standout Papers
- Evaluation of platelet function, a method comparison (2005)
- Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP‐ and thrombin‐induced human platelet activation (2004)
- Characterisation of species differences in the platelet ADP and thrombin response (2005)
- The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation (2003)
Citation Impact
Citing Papers
Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β
2016
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
2020 Standout
Static platelet adhesion, flow cytometry and serum TXB2 levels for monitoring platelet inhibiting treatment with ASA and clopidogrel in coronary artery disease: a randomised cross-over study
2009 StandoutNobel
Platelet thrombin receptor antagonism and atherothrombosis
2009
An in vitro examination of the impact of polyethylene glycol 400, pluronic P85, and vitamin E d-a-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine
2002
Microcapsule-based biosensor containing catechol for the reagent-free inhibitive detection of benzoic acid by tyrosinase
2021 StandoutNobel
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade
2008 Standout
Predicting Oral Absorption and Bioavailability
2003
The Influence of Direct Thrombin Inhibitors on the Formation of Platelet-leukocyte Aggregates and Tissue Factor Expression
2010
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport
2000
Prediction of the Intestinal Absorption of Endothelin Receptor Antagonists Using Three Theoretical Methods of Increasing Complexity
1999
Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework
2014 Standout
Improving drug solubility for oral delivery using solid dispersions
2000 Standout
Platelet-Cancer Interplay: Molecular Mechanisms and New Therapeutic Avenues
2021
Thrombin-induced platelet activation via PAR4: pivotal role for exosite II
2014 StandoutNobel
Dabigatran etexilate – a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity
2010 Standout
Evaluation of AR-H067637, the active metabolite of the new direct thrombin inhibitor AZD0837, in models of venous and arterial thrombosis and bleeding in anaesthetised rats
2010
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Therapeutic applications of compounds in the Magnolia family
2011 Standout
Physicochemical Profiling (Solubility, Permeability and Charge State)
2001
The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence
2015 Standout
Coordinated regulation of myeloid cells by tumours
2012 Standout
Purinergic regulation of the immune system
2016
A systematic comparison of methods to measure HIV-1 specific CD8 T cells
2003
Immunogenic cell death in cancer and infectious disease
2016 Standout
Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix
2007
HIV-Specific Antibodies But Not T-Cell Responses Are Associated With Protection in Seronegative Partners of HIV-1-Infected Individuals in Cambodia
2006 StandoutNobel
Pathophysiology and Therapeutic Potential of Purinergic Signaling
2006
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
2007 Standout
Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs
1998 Standout
The role of thrombin receptors PAR1 and PAR4 for PAI-1 storage, synthesis and secretion by human platelets
2012 StandoutNobel
The ATP-gated P2X1 Receptor Plays a Pivotal Role in Activation of Aspirin-treated Platelets by Thrombin and Epinephrine
2008 StandoutNobel
Ticagrelor
2011
Applicability of an in vitro digestion model in assessing the bioaccessibility of mycotoxins from food
2004 Standout
Current methodologies used for evaluation of intestinal permeability and absorption
2000
Pharmacokinetics and anticoagulant effect of the direct thrombin inhibitor melagatran following subcutaneous administration to healthy young men
2003
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
In vitro and in vivo evaluation of chemically modified degradable starch microspheres for topical haemostasis
2011 StandoutNobel
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
2008 Standout
Antiaggregatory activity in human platelets of potent antagonists of the P2Y1 receptor
2004
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition
2016 Standout
The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation
2015
Experimental models for predicting drug absorption and metabolism
2013
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
The PI3K Pathway in Human Disease
2017 Standout
In Vitro and ex Vivo Intestinal Tissue Models to Measure Mucoadhesion of Poly (Methacrylate) and N-Trimethylated Chitosan Polymers
2005
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
The road map to oral bioavailability: an industrial perspective
2006
Bleeding Risk with Long-Term Low-Dose Aspirin: A Systematic Review of Observational Studies
2016
Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors
2018 StandoutNobel
Improved Prediction of In Vivo Peroral Absorption from In Vitro Intestinal Permeability Using an Internal Standard to Control for Intra- and Inter-Rat Variability
1997
Addressing thrombogenicity in vascular graft construction
2006
Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy
2007
Preclinical and Clinical Studies with Selective Reversible Direct P2Y12Antagonists
2005
Platelet PAR1 receptor density—Correlation to platelet activation response and changes in exposure after platelet activation
2007 StandoutNobel
Pretreatment With P2Y 12 Inhibitors in Non–ST-Segment–Elevation Acute Coronary Syndrome Is Clinically Justified
2014
Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets
2011 StandoutNobel
Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics
2001
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Recent Advances in Electrochemical Biosensors Based on Enzyme Inhibition for Clinical and Pharmaceutical Applications
2018
Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development
2007 StandoutNobel
Prediction of Drug Absorption Using Multivariate Statistics
2000 Standout
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension
2005
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties
2000 Standout
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease
2020 Standout
Functional properties of anthocyanins and betalains in plants, food, and in human nutrition
2003 Standout
Human Jejunal Effective Permeability and Its Correlation with Preclinical Drug Absorption Models
1997
2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation
2015 Standout
Innate immunity as a target for acute cardioprotection
2018
Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success
2009 Standout
Plastic and Human Health: A Micro Issue?
2017 Standout
Receptors for Purines and Pyrimidines
2012 Standout
Human Dendritic Cells Produce TGF-β1 under the Influence of Lung Carcinoma Cells and Prime the Differentiation of CD4+CD25+Foxp3+ Regulatory T Cells
2009
Impact of Timing on the Functional Recovery Achieved With Platelet Supplementation After Treatment With Ticagrelor
2017
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells
2016
2014 AHA/ACC Guideline for the Management of Patients With Non–ST-Elevation Acute Coronary Syndromes
2014 Standout
Metabolism of the Food-Associated Carcinogen 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by Human Intestinal Microbiota
2006
Ticagrelor Compared With Clopidogrel by Geographic Region in the Platelet Inhibition and Patient Outcomes (PLATO) Trial
2011
2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines
2019 Standout
Works of Sven Nylander being referenced
Adenosine-Mediated Effects of Ticagrelor
2014
Ticagrelor inhibits human platelet aggregation via adenosine in addition to P2Y12 antagonism
2013
Effects of autologous platelet transfusion on platelet inhibition in ticagrelor‐treated and clopidogrel‐treated subjects
2016
Membrane Transport of Drugs in Different Regions of the Intestinal Tract of the Rat
1998
Jejunal Permeability: A Comparison Between the Ussing Chamber Technique and the Single-Pass Perfusion in Humans
1997
Human target validation of phosphoinositide 3‐kinase (PI3K)β: effects on platelets and insulin sensitivity, using AZD6482 a novel PI3Kβ inhibitor
2012
Evaluation of platelet function, a method comparison
2005 StandoutNobel
Mode of action of P2Y12 antagonists as inhibitors of platelet function
2010
Brefeldin A, but not monensin, completely blocks CD69 expression on mouse lymphocytes:
1999
Synergistic action between inhibition of P2Y12/P2Y1 and P2Y12/thrombin in ADP‐ and thrombin‐induced human platelet activation
2004 StandoutNobel
Anti‐platelet therapy: cyclo‐oxygenase inhibition and the use of aspirin with particular regard to dual anti‐platelet therapy
2011
Characterisation of species differences in the platelet ADP and thrombin response
2005 StandoutNobel
Thrombin-induced platelet activation and its inhibition by anticoagulants with different modes of action
2003
The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation
2003 StandoutNobel
Structural and functional characterization of a specific antidote for ticagrelor
2015
Ticagrelor Effectively and Reversibly Blocks Murine Platelet P2Y 12 -Mediated Thrombosis and Demonstrates a Requirement for Sustained P2Y 12 Inhibition to Prevent Subsequent Neointima
2010
Ticagrelor Protects the Heart Against Reperfusion Injury and Improves Remodeling After Myocardial Infarction
2015