Citation Impact
Citing Papers
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Maintenance of Constitutive IκB Kinase Activity by Glycogen Synthase Kinase-3α/β in Pancreatic Cancer
2008
Activating Smoothened mutations in sporadic basal-cell carcinoma
1998 StandoutNature
Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles
2019 Standout
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
2007 Standout
Engineering proteinase K using machine learning and synthetic genes
2007
Towards the chemometric dissection of peptide – HLA-A*0201 binding affinity: comparison of local and global QSAR models
2005
Dynamic Interplay between O-Linked N-Acetylglucosaminylation and Glycogen Synthase Kinase-3-dependent Phosphorylation
2007
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Classification of G‐protein coupled receptors by alignment‐independent extraction of principal chemical properties of primary amino acid sequences
2002
Computational Enzyme Design
2013 StandoutNobel
Mathematical modelling of insect neuropeptide potencies. Are quantitatively predictive models possible?
2000
AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test
2004
Molecular similarity analysis: an alternative approach to studying molecular mechanisms of anaesthesia
1998
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Mechanisms of Actions of Inhaled Anesthetics
2003 Standout
Expanding the Enzyme Universe: Accessing Non‐Natural Reactions by Mechanism‐Guided Directed Evolution
2015 StandoutNobel
Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation
2007
The genotoxicity of 3-nitrobenzanthrone and the nitropyrene lactones in human lymphoblasts
2000
On the effect of pH in aromatic photonitration upon nitrate photolysis
2006
Designing antimicrobial peptides: form follows function
2011 Standout
The Ectodomain of the Luteinizing Hormone Receptor Interacts with Exoloop 2 to Constrain the Transmembrane Region
2002 StandoutNobel
Modern Synthetic Methods for Copper‐Mediated C(aryl)O, C(aryl)N, and C(aryl)S Bond Formation
2003 Standout
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
GSK3 inhibitors: development and therapeutic potential
2004
GSK-3-Selective Inhibitors Derived from Tyrian Purple Indirubins
2003 Standout
Design, synthesis and evaluation of peptide inhibitors of Mycobacterium tuberculosis ribonucleotide reductase
2007
Responsive Cyclohexane‐Based Low‐Molecular‐Weight Hydrogelators with Modular Architecture
2004 StandoutNobel
Improving catalytic function by ProSAR-driven enzyme evolution
2007
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
2017 StandoutNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Ultrasound assisted one-pot, three-components synthesis of pyrimido[1,2-a]benzimidazoles and pyrazolo[3,4-b]pyridines: A new access via phenylsulfone synthon
2011
Activation of the Luteinizing Hormone Receptor Following Substitution of Ser-277 with Selective Hydrophobic Residues in the Ectodomain Hinge Region
2000 StandoutNobel
Bending membranes to the task: structural intermediates in bilayer fusion
1995
AKT/PKB Signaling: Navigating the Network
2017 Standout
Coumarin, chromone, and 4(3H)-pyrimidinone novel bicyclic and tricyclic derivatives as antiplatelet agents: synthesis, biological evaluation, and comparative molecular field analysis
2003
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Toxicology for the twenty-first century
2009 StandoutNature
Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)
2007
Role that phosphorylation of GSK3 plays in insulin and Wnt signalling defined by knockin analysis
2005
Engineering the third wave of biocatalysis
2012 StandoutNature
SuFEx‐Based Polysulfonate Formation from Ethenesulfonyl Fluoride–Amine Adducts
2017 StandoutNobel
Ultrasensitive Chemical Analysis by Raman Spectroscopy
1999 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Sulfonyl Fluorides as Alternative to Sulfonyl Chlorides in Parallel Synthesis of Aliphatic Sulfonamides
2014
Metabolic cross-talk allows labeling of O-linked β- N -acetylglucosamine-modified proteins via the N -acetylgalactosamine salvage pathway
2011 StandoutNobel
PLS-SEM: Indeed a Silver Bullet
2011 Standout
A PLS kernel algorithm for data sets with many variables and fewer objects. Part 1: Theory and algorithm
1994
Principal component analysis
1987 Standout
Close Is Not Enough
2000 StandoutNobel
Latent variable multivariate regression modeling
1999
A test of significance for partial least squares regression
1993
New Chemical Descriptors Relevant for the Design of Biologically Active Peptides. A Multivariate Characterization of 87 Amino Acids
1998
The activation process of the α 1B -adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
1997
A Method for Monitoring the Surface Conservation of Wooden Objects by Raman Spectroscopy and Multivariate Control Charts
2003
Comprehensive Survey of Combinatorial Library Synthesis: 2002
2003
Analysis of Peptide−Protein Binding Using Amino Acid Descriptors: Prediction and Experimental Verification for Human Histocompatibility Complex HLA-A*0201
2005
Statistical analysis and intercomparison of WAM model data with global ERS‐1 SAR wave mode spectral retrievals over 3 years
1998 StandoutNobel
PLS-regression: a basic tool of chemometrics
2001 Standout
Structure‐Lipophilicity and Structure‐Polarity relationships of amino acids and peptides
1995
Bartramiaflavone, a macrocyclic biflavonoid from the moss Bartramia pomiformis
1991
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Toward an evidence-based toxicology
2006
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Sulfonamide Synthesis via Calcium Triflimide Activation of Sulfonyl Fluorides
2018
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
2004
Learned protein embeddings for machine learning
2018 StandoutNobel
Iron-catalyzed Cross-Coupling of Electron-Deficient Heterocycles and Quinone with Organoboron Species via Innate C–H Functionalization: Application in Total Synthesis of Pyrazine Alkaloid Botryllazine A
2013
Preprocessing peptide sequences for multivariate sequence-property analysis
1998
Recent Developments in the Preparation and Chemistry of Metallacycles and Metallacages via Coordination
2015 Standout
Quantitative Structure−Activity Relationship Modeling of Peptide and Protein Behavior as a Function of Amino Acid Composition
2000
Catalytic Dehydrogenation of Light Alkanes on Metals and Metal Oxides
2014 Standout
Membrane Fusion and Exocytosis
1999 StandoutNobel
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Multivariate analysis of carbon-13 nuclear magnetic resonance spectra. Identification and quantification of average structures in petroleum distillates
1990
Polypeptide sequence property relationships in Escherichia coli based on auto cross covariances
1995
Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders: Structure−Activity Relationship
2004
Environmental Implications of Hydroxyl Radicals (•OH)
2015 Standout
A family of thermostable fungal cellulases created by structure-guided recombination
2009 StandoutNobel
A Decade of Raman Spectroscopy in Art and Archaeology
2007 Standout
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
The selectivity of protein kinase inhibitors: a further update
2007 Standout
Emerging Targets in Photopharmacology
2016 StandoutNobel
DNA and peptide sequences and chemical processes multivariately modelled by principal component analysis and partial least-squares projections to latent structures
1993
Quantitative Understanding of Guest Binding Enables the Design of Complex Host–Guest Behavior
2013
Nascent-Seq analysis of Drosophila cycling gene expression
2013 StandoutNobel
Sources of the atmospheric contaminants, 2-nitrobenzanthrone and 3-nitrobenzanthrone
2003
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Octan-1-ol–water partition coefficients of zwitterionic α-amino acids. Determination by centrifugal partition chromatography and factorization into steric/hydrophobic and polar components
1992
A multivariate study of the relationship between the genetic code and the physical-chemical properties of amino acids
1985
Prediction of Nucleating Sequences from Amyloidogenic Propensities of Tau-Related Peptides
2006
In situ UV–Vis diffuse reflectance spectroscopy — on line activity measurements of supported chromium oxide catalysts: relating isobutane dehydrogenation activity with Cr-speciation via experimental design
2000
Metal-Free Multicomponent Syntheses of Pyridines
2014 Standout
Works of Sven Hellberg being referenced
Modelling data tables by principal components and PLS: class patterns and quantitative predictive relations
1984
Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418
2003
A Multivariate Representation and Analysis of DNA Sequence Data.
1991
Peptide QSAR on Substance P Analogues, Enkephalins, and Bradykinins Containing L- and D-Amino Acids.
1990
Minimum analogue peptide sets (MAPS) for quantitative structure‐activity relationships
1991
MEIC—A new international multicenter project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests
1989
Similar regulatory mechanisms despite differences in membrane lipid composition in Acholeplasma laidlawii strains A-EF22 and B-PG9. A multivariate data analysis
1994
Multivariate Data Analysis of Substituent Descriptors.
1983
Clustering of aryl carbon-13 nuclear magnetic resonance substituent chemical shifts. A multivariate data analysis using principal components
1983
The Prediction of Bradykinin Potentiating Potency of Pentapeptides. An Example of a Peptide Quantitative Structure-activity Relationship.
1986
Anticonvulsant activity of a nonpeptide galanin receptor agonist
2002
Multivariate Parametrization of 55 Coded and Non‐Coded Amino Acids
1989
Peptide quantitative structure-activity relationships, a multivariate approach
1987
ChemInform Abstract: The Prediction of Bradykinin Potentiating Potency of Pentapeptides.
1986
Chemical Studies on Bryophytes. 23. 13C NMR Analysis of a Biflavone from Dicranum scoparium.
1983
Nitration of Polycyclic Aromatic Hydrocarbons with Dinitrogen Tetroxide. A Simple and Selective Synthesis of Mononitro Derivatives.
1983
Discovery of Novel Potent and Highly Selective Glycogen Synthase Kinase-3β (GSK3β) Inhibitors for Alzheimer’s Disease: Design, Synthesis, and Characterization of Pyrazines
2012
ChemInform Abstract: MULTIVARIATE DATA ANALYSIS OF SUBSTITUENT DESCRIPTORS
1983
Multivariate structure‐activity relationships between data from a battery of biological tests and an ensemble of structure descriptors: The PLS method
1984
Multivariate design
1986
The Anesthetic Activity and Toxicity of Halogenated Ethyl Methyl Ethers, a Multivariate QSAR Modelled by PLS
1985