Citation Impact
Citing Papers
A hexahistidine-Zn 2+ -dye label reveals STIM1 surface exposure
2007 StandoutNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
The lymphocyte‐specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2
1989
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Structural organization of gap junction channels
2005
The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain
1989
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg
1992 StandoutNobel
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
p53-Mdm2--the affair that never ends
2002
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1992 Standout
Mechanisms of transformation by polyoma virus middle T antigen
1989
Phosphorylation of middle T by pp60c-src: A switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis
1989
Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src
1991 Nature
When Checkpoints Fail
1997 StandoutNobel
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
1992 StandoutNobel
Constitutive activation of Src family kinases in mouse embryos that lack Csk
1993
The SH2-containing protein-tyrosine phosphatase SH-PTP2 is required upstream of MAP kinase for early xenopus development
1995
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Tumor suppressor genes
1991 Standout
The p53 pathway
1999
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement
1997 Nature
Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivation
1996
CD4: Collaborator in immune recognition and HIV infection
1990 StandoutNobel
Phosphorylation of c-Crk II on the Negative Regulatory Tyr222 Mediates Nerve Growth Factor-induced Cell Spreading and Morphogenesis
2000
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase
1989 StandoutNobel
Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice
1993
Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain
1999
Oncogenes and signal transduction
1991 Standout
Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
1997 StandoutNobel
Crystal structure of the Src family tyrosine kinase Hck
1997 Nature
Substrates for p34cdc2: In vivo veritas?
1990 StandoutNobel
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
Serotonin 5-HT1A Receptor-mediated Erk Activation Requires Calcium/Calmodulin-dependent Receptor Endocytosis
1999 StandoutNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
A DNA Damage–Induced p53 Serine 392 Kinase Complex Contains CK2, hSpt16, and SSRP1
2001
Mechanisms of switching on p53: a role for covalent modification?
1999
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A
1990
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
1989 StandoutNatureNobel
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1991 StandoutNatureNobel
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
1992
A role for casein kinase 2α in the Drosophila circadian clock
2002 StandoutNatureNobel
Activation of the cryptic DNA binding function of mutant forms of p53
1993
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Solution structure of the tetrameric minimum transforming domain of p53
1994
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Universal control mechanism regulating onset of M-phase
1990 StandoutNatureNobel
Molecular Interactions, T‐Cell Subsets and a Role of the CD4/CD8:p56lck Complex in Human T‐Cell Activation
1989
Association of p62c-yes with polyomavirus middle T-antigen mutants correlates with transforming ability
1990
Regulation of pp60c-src and its interaction with polyomavirus middle T antigen in insect cells
1990
Characterization of pp85, a target of oncogenes and growth factor receptors.
1990
Association of the polyomavirus middle-T antigen with c-yes protein
1987 Nature
The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity.
1995 StandoutNobel
Altered phosphorylation and activation of PP60c-src during fibroblast mitosis
1988
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.
1991
Platelet-derived growth factor induces rapid and sustained tyrosine phosphorylation of phospholipase C-gamma in quiescent BALB/c 3T3 cells.
1989
Genetic determinants of neoplastic transformation by the retroviral oncogene v-erbB.
1988 StandoutNobel
Association of protein phosphatase 2A with polyoma virus medium tumor antigen.
1990
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Expression of v-src induces aberrant development and twinning in chimaeric mice
1991 StandoutNobel
Monoclonal antibodies to individual tyrosine-phosphorylated protein substrates of oncogene-encoded tyrosine kinases.
1990
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
Elevated expression of pp60c-src alters a selective morphogenetic property of epithelial cells in vitro without a mitogenic effect.
1988
Structural elements that regulate pp59c-fyn catalytic activity, transforming potential, and ability to associate with polyomavirus middle-T antigen
1991
The rate of nuclear cytoplasmic protein transport is determined by the casein kinase II site flanking the nuclear localization sequence of the SV40 T-antigen.
1991
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion.
1988
A Protein Tyrosine Kinase Involved in Regulation of pp60c-src function
1989
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck).
1988
Human DNA-Activated Protein Kinase Phosphorylates Serines 15 and 37 in the Amino-Terminal Transactivation Domain of Human p53
1992
The Cellular src Gene Product Regulates Junctional Cell-to-Cell Communication
1988 Science
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527.
1988
Surfing the p53 network
2000 StandoutNature
Mechanism of Activation of Complexed pp60 c-src by the Middle T Antigen of Polyomavirus
1989
A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity
1990
A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.
1988
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src.
1990
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirus.
1988
Csk suppression of Src involves movement of Csk to sites of Src activity.
1994
Altered sites of tyrosine phosphorylation in pp60c-src associated with polyomavirus middle tumor antigen.
1986
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein.
1989
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer
1989 StandoutScience
Identification and characterization of p59fyn (a src-like protein tyrosine kinase) in normal and polyoma virus transformed cells.
1988
Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.
1988 StandoutNobel
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.
1987
Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB
1988
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Rapid activation of sodium–proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades
1998
Evidence for epidermal growth factor (EGF)-induced intermolecular autophosphorylation of the EGF receptors in living cells.
1990
Stable Association of Activated pp60src with Two Tyrosine-Phosphorylated Cellular Proteins
1989
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.
1996 Nobel
The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus.
1988
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity.
1988
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
The amino terminus of polyomavirus middle T antigen is required for transformation
1990
Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.
1988
Neoplastic Transformation Induced by an Activated Lymphocyte-Specific Protein Tyrosine Kinase (pp56lck)
1988 StandoutNobel
Works of Suzanne Simon being referenced
Tyrosine Phosphorylation of Connexin 43 by v-Src Is Mediated by SH2 and SH3 Domain Interactions
1997
Cell transformation by pp60c-src mutated in the carboxy-terminal regulatory domain
1987
cDNA cloning with a retrovirus expression vector: generation of a pp60c-src cDNA clone
1987
Truncated forms of the polyomavirus middle T antigen can substitute for the small T antigen in lytic infection
1986
Polyomavirus middle T protein encoded by a retrovirus transforms nonestablished chicken embryo cells
1985
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.
1990