Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells
2006
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
IFN-γ-induced Th1-Treg polarization in inflamed brains limits exacerbation of experimental autoimmune encephalomyelitis
2024
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
2010
IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells
2007
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Mechanisms of type-I- and type-II-interferon-mediated signalling
2005 Standout
Inflammation and cancer
2002 StandoutNature
Histone Deacetylase Activity Is Required for Full Transcriptional Repression by mSin3A
1997
A Linear Signal Transduction Pathway Involving Phosphatidylinositol 3-Kinase, Protein Kinase Cϵ, and MAPK in Mesangial Cells Regulates Interferon-γ-induced STAT1α Transcriptional Activation
2004
Oxidative stress and gene regulation
2000
c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms
1999
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
Structure and function of the vomeronasal system: an update
2003
The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo
1993 StandoutNobel
Regulatory T Cells in Cancer
2010
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by Stat5 and Histone Acetylation
2001 StandoutNobel
Proteasome- and p53-dependent Masking of Signal Transducer and Activator of Transcription (STAT) Factors
1997 StandoutNobel
Coordinated regulation of myeloid cells by tumours
2012 Standout
Immunosuppressive CD14+HLA‐DRlow/− monocytes in prostate cancer
2009
The Signal-Dependent Coactivator CBP Is a Nuclear Target for pp90RSK
1996
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 Standout
Role of the Common Cytokine Receptor γ Chain in Cytokine Signaling and Lymphoid Development
1995
The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain
1993
Induction of Germline Transcription in the TCRγ Locus by Stat5
1999 StandoutNobel
Distinct Roles of the Phosphatidylinositol 3-Kinase and STAT5 Pathways in IL-7-Mediated Development of Human Thymocyte Precursors
1999
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells
1994 Standout
The role of STATs in transcriptional control and their impact on cellular function
2000
STAT proteins and transcriptional responses to extracellular signals
2000
Essential role of Stat6 in IL-4 signalling
1996 Nature
Stat6 Is Required for Mediating Responses to IL-4 and for the Development of Th2 Cells
1996
CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages
2009
The Earliest T Lineage–Committed Cells Depend on IL-7 for Bcl-2 Expression and Normal Cell Cycle Progression
1997
Decoupling the Functional Pleiotropy of Stem Cell Factor by Tuning c-Kit Signaling
2017
How regulatory T cells work
2008 Standout
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
2010 Standout
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
1995
Ceramide Activates the Stress-activated Protein Kinases
1995
Protein Kinase Cδ Regulates Apoptosis via Activation of STAT1
2004
Complex roles of Stat1 in regulating gene expression
2000
IgG4-related disease
2014 Standout
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Modulation of STAT signaling by STAT-interacting proteins
2000
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
Steroid hormone receptors: Many Actors in search of a plot
1995 Standout
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
The Coactivator of Transcription CREB-binding Protein Interacts Preferentially with the Glycosylated Form of Stat5
2004
Cytokine and Cytokine Receptor Pleiotropy and Redundancy
2002
Cancer-related inflammation
2008 StandoutNature
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Interleukin‐13 selectively induces monocyte chemoattractant protein‐1 synthesis and secretion by human endothelial cells. Involvement of IL‐4Rα and Stat6 phosphorylation
1997
Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site
2002
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation
2009
Stat5 Is Required for IL-2-Induced Cell Cycle Progression of Peripheral T Cells
1999
Functional Importance of Stat3 Tetramerization in Activation of the α2-Macroglobulin Gene
2001
Irresistible force meets immovable object: Transcription and the nucleosome
1991 StandoutNobel
STATs: transcriptional control and biological impact
2002 Standout
ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
1999
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
A Stat3-interacting protein (StIP1) regulates cytokine signal transduction
2000
Interleukin 7 receptor-deficient mice lack gammadelta T cells.
1996
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
2016 Standout
Interleukin-7 Upregulates the Interleukin-2–Gene Expression in Activated Human T Lymphocytes at the Transcriptional Level by Enhancing the DNA Binding Activities of Both Nuclear Factor of Activated T Cells and Activator Protein-1
1997
Involvement of the Extracellular Signal-Regulated Kinase Cascade for Cocaine-Rewarding Properties
2000
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.
1991
JAKS AND STATS: Biological Implications
1998 Standout
Identification and Characterization of a Constitutively Active STAT5 Mutant That Promotes Cell Proliferation
1998
Induction of Germline Transcription in the Human TCRγ Locus by STAT5
2001 StandoutNobel
Structure of the Amino-Terminal Protein Interaction Domain of STAT-4
1998 Science
Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development
1995 Science
Differentiation requires continuous regulation.
1991 Nobel
Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals
2007 StandoutNobel
Interferon- Activates Multiple STAT Proteins and Upregulates Proliferation-Associated IL-2R, c-myc, and pim-1 Genes in Human T Cells
1999
Activation of Different Stat5 Isoforms Contributes to Cell-Type-Restricted Signaling in Response to Interferons
1996
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
The murine IL-13 receptor alpha 2: molecular cloning, characterization, and comparison with murine IL-13 receptor alpha 1.
1998
Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm
1996
Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase.
1993 Nobel
DNA Binding Specificity of Different STAT Proteins
2001
MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
1995
Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice
2010
The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.
1996
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Maximal Induction of a Subset of Interferon Target Genes Requires the Chromatin-Remodeling Activity of the BAF Complex
2002
The Mos/MAP kinase pathway stabilizes c-Fos by phosphorylation and augments its transforming activity in NIH 3T3 cells.
1995
High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells
1999 StandoutNobel
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility
1998
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
The Murine IL-13 Receptor α2: Molecular Cloning, Characterization, and Comparison with Murine IL-13 Receptor α1
1998
Role of the Stat4 N Domain in Receptor Proximal Tyrosine Phosphorylation
2000
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 Standout
Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.
1996
Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes
2001
THE UBIQUITIN SYSTEM
1998 StandoutNobel
THE IFNγ RECEPTOR:A Paradigm for Cytokine Receptor Signaling
1997
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Signal Transducer and Activator of Transcription Factor 6 (Stat6)-deficient Mice Are Protected from Antigen-induced Airway Hyperresponsiveness and Mucus Production
1998
Works of Susan John being referenced
CD4 + CD25 + Foxp3 + regulatory T cells induce alternative activation of human monocytes/macrophages
2007
Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames.
1995
Seasonal Cell Proliferation in the Chemosensory Epithelium and Brain of Red-Backed Salamanders, <i>Plethodon cinereus</i>
2000
Functional Association of Nmi with Stat5 and Stat1 in IL-2- and IFN γ-Mediated Signaling
1999
Functional analysis of a growth factor-responsive transcription factor complex
1993
The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
1995
A Single Residue Modulates Tyrosine Dephosphorylation, Oligomerization, and Nuclear Accumulation of Stat Transcription Factors
2004
Lack of Suppressive CD4+CD25+FOXP3+ T Cells in Advanced Stages of Primary Cutaneous T-Cell Lymphoma
2006
Cloning of Human Stat5B
1996
Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate.
1990
Regulation of Cell-Type-Specific Interleukin-2 Receptor α-Chain Gene Expression: Potential Role of Physical Interactions between Elf-1, HMG-I(Y), and NF-κ B Family Proteins
1995
An IL-2 response element in the human IL-2 receptor alpha chain promoter is a composite element that binds Stat5, Elf-1, HMG-I(Y) and a GATA family protein.
1996
The Significance of Tetramerization in Promoter Recruitment by Stat5
1999
DNA Binding Site Selection of Dimeric and Tetrameric Stat5 Proteins Reveals a Large Repertoire of Divergent Tetrameric Stat5a Binding Sites
2000