Standout Papers
Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Single Reconstituted Neuronal SNARE Complexes Zipper in Three Distinct Stages
2012 StandoutScienceNobel
Functional Genomic Analysis of RNA Interference in C. elegans
2005 StandoutScienceNobel
Genome sequence of an industrial microorganism Streptomyces avermitilis : Deducing the ability of producing secondary metabolites
2001 StandoutNobel
Primary sequence of the glucanase gene from Oerskovia xanthineolytica. Expression and purification of the enzyme from Escherichia coli.
1991
De novo design of modular and tunable protein biosensors
2021 StandoutNatureNobel
DnaG interacts with a linker region that joins the N- and C-domains of DnaB and induces the formation of 3-fold symmetric rings
2004
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Lyme Disease
1989 Standout
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Quaternary Polymorphism of Replicative Helicase G40P: Structural Mapping and Domain Rearrangement
2006
The Bacterial Helicase-Primase Interaction: A Common Structural/Functional Module
2005
Mitogen-activated protein kinase pathways
1997 Standout
Regulation of bacterial priming and daughter strand synthesis through helicase-primase interactions
2006
Cascade regulation of nif gene expression in Rhizobium meliloti
1988
The 3′-tail of a forked-duplex sterically determines whether one or two DNA strands pass through the central channel of a replication-fork helicase
2000
The Structure of T. aquaticus DNA Polymerase III Is Distinct from Eukaryotic Replicative DNA Polymerases
2006 StandoutNobel
Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain
2003 StandoutNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry
2007
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
The Crystal Structure of TREX1 Explains the 3′ Nucleotide Specificity and Reveals a Polyproline II Helix for Protein Partnering
2007
Mechanism and Stoichiometry of Interaction of DnaG Primase with DnaB Helicase of Escherichia coli in RNA Primer Synthesis
2003
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Solution Structure of the Helicase-Interaction Domain of the Primase DnaG
2005
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Structure of the Dimeric Exonuclease TREX1 in Complex with DNA Displays a Proline-rich Binding Site for WW Domains
2007
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
The crystal structure of the Thermus aquaticus DnaB helicase monomer
2007 StandoutNobel
Functional Proteomics Reveals the Biochemical Niche of C. elegans DCR-1 in Multiple Small-RNA-Mediated Pathways
2006 StandoutNobel
Crystallographic Structure of the Nuclease Domain of 3′hExo, a DEDDh Family Member, Bound to rAMP
2004
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
XMIPP: a new generation of an open-source image processing package for electron microscopy
2004
Nucleases: diversity of structure, function and mechanism
2010
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
Sec61p and BiP directly facilitate polypeptide translocation into the ER
1992 StandoutNobel
The NH2-terminal php Domain of the α Subunit of the Escherichia coli Replicase Binds the ϵ Proofreading Subunit
2006
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Flexibility of the Rings: Structural Asymmetry in the DnaB Hexameric Helicase
2002
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Monomeric solution structure of the helicase‐binding domain of Escherichia coli DnaG primase
2006
Crystal and Solution Structures of the Helicase-binding Domain of Escherichia coli Primase
2005
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Circulating Immune Complexes in Lyme Arthritis
1979
In the Bacillus stearothermophilus DnaB-DnaG Complex, the Activities of the Two Proteins Are Modulated by Distinct but Overlapping Networks of Residues
2006
Immune Complexes and the Evolution of Lyme Arthritis
1979
Correlation of Serum and Cryoglobulin IgM with Activity, and Serum IgG with Remission
1979
Circular permutation and receptor insertion within green fluorescent proteins
1999 StandoutNobel
The use of transposon Tn5 mutagenesis in the rapid generation of correlated physical and genetic maps of DNA segments cloned into multicopy plasmids — a review
1984
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering
2001 StandoutNobel
Mapping Protein−Protein Interactions within a Stable Complex of DNA Primase and DnaB Helicase from Bacillus stearothermophilus
1999
Temperature Dependence of Voltage-gated H+ Currents in Human Neutrophils, Rat Alveolar Epithelial Cells, and Mammalian Phagocytes
1998
CELLULAR DNA REPLICASES: Components and Dynamics at the Replication Fork
2005
Genetically Encoded Fluorescent Biosensors Illuminate the Spatiotemporal Regulation of Signaling Networks
2018
Cases of Lyme Disease in the United States: Locations Correlated with Distribution of Ixodes dammini
1979
Lyme Disease—a Tick-Borne Spirochetosis?
1982 StandoutScience
Ligand-Dependent Equilibrium Fluctuations of Single Calmodulin Molecules
2009 Science
Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa
1999
Transposon mutagenesis by Tn4560 and applications with avermectin-producing Streptomyces avermitilis
1993 StandoutNobel
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Structure classification-based assessment of CASP3 predictions for the fold recognition targets
1999
A Bipartite Polymerase–Processivity Factor Interaction: Only the Internal β Binding Site of the α Subunit is Required for Processive Replication by the DNA Polymerase III Holoenzyme
2005
Protein phosphorylation and regulation of adaptive responses in bacteria
1989
Directed transposon Tn5 mutagenesis and complementation analysis of rhizobium meliloti symbiotic nitrogen fixation genes
1982 StandoutNobel
Ab initio protein structure prediction of CASP III targets using ROSETTA
1999 StandoutNobel
Avermectin Biosynthesis
1997 StandoutNobel
Artificial Organic Host Molecules for Anions
1997 Standout
Conformational enantiomerism of bilirubin and pamoic acid induced by protonated aminocyclodextrins
1995
Spatiotemporal dynamics of guanosine 3′,5′-cyclic monophosphate revealed by a genetically encoded, fluorescent indicator
2001 StandoutNobel
REGULATION OF THE CELL DIVISION CYCLE AND DIFFERENTIATION IN BACTERIA
1990
Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins
1998 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Imaging the glycome
2008 StandoutNobel
Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells
2001 StandoutNobel
Chronic Lyme Arthritis
1979
Elevated levels of collagenase and prostaglandin e2 from synovium associated with chronic lyme arthritis
1980
Structure of Hexameric DnaB Helicase and Its Complex with a Domain of DnaG Primase
2007 StandoutScienceNobel
Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae
1986 StandoutNobel
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3
2008 StandoutNobel
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
The bacterial replicative helicase DnaB evolved from a RecA duplication.
2000
Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells
1998 StandoutScienceNobel
The Spirochetal Etiology of Lyme Disease
1983 Standout
Dynamic and quantitative Ca 2+ measurements using improved cameleons
1999 StandoutNobel
Works of Susan E. Brown being referenced
Use of electrospray ionization mass spectrometry to study binding interactions between a replication terminator protein and DNA
2002
Kinetic Control of the Dissociation Pathway of Calmodulin-Peptide Complexes
1997
NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer
1999
Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
2002
The DnaB·DnaC complex: a structure based on dimers assembled around an occluded channel
2001
pH-controlled quaternary states of hexameric DnaB helicase
2000
Tyrosine kinase growth factor receptors but not seven-membrane-spanning receptors or phorbol esters activate mitogen-activated protein kinase in rat hepatocytes
1995
Construction of a broad host range cosmid cloning vector and its use in the genetic analysis of Rhizobium mutants
1982
pHi regulation in alveolar macrophages: relative roles of Na(+)-H+ antiport and H(+)-ATPase
1994
Spectroscopic Characterization of a High-Affinity Calmodulin−Target Peptide Hybrid Molecule
1996
Inhibition of Protein Interactions with the β2 Sliding Clamp of Escherichia coli DNA Polymerase III by Peptides from β2-Binding Proteins
2004
Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region.
1983
ERYTHEMA CHRONICUM MIGRANS AND LYME ARTHRITIS: FIELD STUDY OF TICKS
1978
ATP-dependent pHi recovery in lung macrophages: evidence for a plasma membrane H(+)-ATPase
1990
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis
1982 StandoutNobel
Substituent effects and chiral discrimination in the complexation of benzoic, 4-methylbenzoic and (RS)-2-phenylpropanoic acids and their conjugate bases by β-cyclodextrin and 6A-amino-6A-deoxy-β-cyclodextrin in aqueous solution: potentiometric titration and1H nuclear magnetic resonance spectroscopic study
1993
Nitrogen fixation by Klebsiella pneumoniae is inhibited by certain multicopy hybrid nif plasmids
1983
Interaction of the Escherichia coli Replication Terminator Protein (Tus) with DNA: A Model Derived from DNA-Binding Studies of Mutant Proteins by Surface Plasmon Resonance
2000