Standout Papers
Citation Impact
Citing Papers
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
A Neural Circuit for Memory Specificity and Generalization
2013 StandoutScienceNobel
Gating the Selectivity Filter in ClC Chloride Channels
2003 StandoutScienceNobel
Peroxynitrite Inhibits Glutamate Transporter Subtypes
1996
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter
1992
Aspartate 338 contributes to the cationic specificity and to driver-amino acid coupling in the insect cotransporter KAAT1
2004
The elusive transporters with a high affinity for glutamate
1993
Sex Determination in Drosophila melanogaster
1990
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Structure of a glutamate transporter homologue from Pyrococcus horikoshii
2004 Nature
Transmembrane Domain III Plays an Important Role in Ion Binding and Permeation in the Glycine Transporter GLYT2
2000
Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain
1993
Role of the GABA Transporter in Epilepsy
2004
Rapid gating and anion permeability of an intracellular aquaporin
1999 StandoutNatureNobel
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Alternative splicing in individual aplysia neurons generates neuropeptide diversity
1987 StandoutNobel
Critical Amino Acid Residues in Transmembrane Span 7 of the Serotonin Transporter Identified by Random Mutagenesis
1998
The Role of External Loop Regions in Serotonin Transport
1999
Plasma membrane monoamine transporters: structure, regulation and function
2003
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors
1988 Nature
The Family of Na+/Cl− Neurotransmitter Transporters
1998
Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics
2009 Nobel
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
Molecular characterization of the dopamine transporter
1993
Pharmacologically distinct sodium-dependentl-[3H]glutamate transport processes in rat brain
1991
Cloning and functional characterization of a cocaine‐sensitive dopamine transporter
1991
The Third Transmembrane Domain of the Serotonin Transporter Contains Residues Associated with Substrate and Cocaine Binding
1997
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Sodium-Dependent Neurotransmitter TRANSPORTERS: OLIGOMERIZATION as a Determinant of Transporter Function and Trafficking
2004
Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system
1993
A distributional code for value in dopamine-based reinforcement learning
2020 StandoutNatureNobel
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
2005 StandoutNature
Expansion of the eukaryotic proteome by alternative splicing
2010 StandoutNature
The role of substance P and calcitonin gene-related peptide in neurogenic plasma extravasation and vasodilatation in the rat
1989
Molecular cloning of two glutamate transporter subtypes from mouse brain
1995
Neuronal and Glial Glycine Transporters Have Different Stoichiometries
2000
Crystal structure of an HIV-binding recombinant fragment of human CD4
1990 StandoutNatureNobel
Characterization of a Functional Bacterial Homologue of Sodium-dependent Neurotransmitter Transporters
2003
Deriving the Glutamate Clearance Time Course from Transporter Currents in CA1 Hippocampal Astrocytes: Transmitter Uptake Gets Faster during Development
2005
Tyrosine 140 of the γ-Aminobutyric Acid Transporter GAT-1 Plays a Critical Role in Neurotransmitter Recognition
1997
Substrate-induced Conformational Changes of Extracellular Loop 1 in the Glycine Transporter GLYT2
2001
Imprinting of acetylcholine receptor messenger RNA accumulation in mammalian neuromuscular synapses
1990 StandoutNatureNobel
Mutation of Arginine 44 of GAT-1, a (Na+ + Cl−)-coupled γ-Aminobutyric Acid Transporter from Rat Brain, Impairs Net Flux but Not Exchange
2000
Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders
2002
Characterization of a mouse strain expressing Cre recombinase from the 3′ untranslated region of the dopamine transporter locus
2006
Identification of Intracellular Residues in the Dopamine Transporter Critical for Regulation of Transporter Conformation and Cocaine Binding
2004
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Messenger plasticity in primary sensory neurons following axotomy and its functional implications
1994
Glutamate Release Monitored with Astrocyte Transporter Currents during LTP
1998
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
2005
Na+ and the substrate permeation pathway in dopamine transporters
2003
Cloning and expression of a rat brain L-glutamate transporter
1992 Nature
Determination of External Loop Topology in the Serotonin Transporter by Site-directed Chemical Labeling
1998
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis
1995
Analysis of Transmembrane Domain 2 of Rat Serotonin Transporter by Cysteine Scanning Mutagenesis
2004
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
α-Neurexins couple Ca2+ channels to synaptic vesicle exocytosis
2003 StandoutNatureNobel
Calcitonin Gene-Related Peptide and Cerebral Blood Vessels: Distribution and Vasomotor Effects
1987
Glutamate‐101 is critical for the function of the sodium and chloride‐coupled GABA transporter GAT‐1
1995
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Cloning and Expression of a Rat Brain GABA Transporter
1990 Science
Optogenetic Dissection of Entorhinal-Hippocampal Functional Connectivity
2013 StandoutScienceNobel
Homologies Between Signal Transducing G Proteins and ras Gene Products
1984 StandoutScienceNobel
Yeast α factor is processed from a larger precursor polypeptide: The essential role of a membrane-bound dipeptidyl aminopeptidase
1983 StandoutNobel
Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution
1985 StandoutScienceNobel
Molecular cloning and expression of cDNAs for the human interleukin-2 receptor
1984 Nature
Primary structure and expression of a functional human glucocorticoid receptor cDNA
1985 StandoutNature
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Splice Junctions: Association with Variation in Protein Structure
1983 Science
Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene
1983 Nature
Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing
1984 Nature
PRE-mRNA SPLICING
1986
Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1
1997 Science
Isolation and characterization of human calcitonin gene-related peptide
1984 Nature
A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing
2000
Generation of an activating Zn 2+ switch in the dopamine transporter: Mutation of an intracellular tyrosine constitutively alters the conformational equilibrium of the transport cycle
2002
In Situ Hybridization to Study the Origin and Fate of Identified Neurons
1983 StandoutScienceNobel
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related
1983 StandoutNatureNobel
A single gene encodes multiple neuropeptides mediating a stereotyped behavior
1983 StandoutNobel
Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways.
1987
Calcitonin gene-related peptide is a potent vasodilator
1985 StandoutNature
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
Amino Acid Residues that Control pH Modulation of Transport-Associated Current in Mammalian Serotonin Transporters
1998
Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1
1983 Nature
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding.
1992
Alternative RNA splicing of the murine αA-crystallin gene: Protein-coding information within an intron
1983
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Dopamine transporter expression confers cytotoxicity to low doses of the parkinsonism-inducing neurotoxin 1-methyl-4-phenylpyridinium
1993
Transcription termination and 3′ processing: the end is in site!
1985
Glucocorticoid-mediated induction of alpha 1-acid glycoprotein: evidence for hormone-regulated RNA processing.
1984
Molecular Structure and Physiological Function of Chloride Channels
2002
Structural Determinants of Ion Flow Through Recombinant Glutamate Receptor Channels
1991 StandoutScienceNobel
The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.
1989 Standout
The concept of chemical neurotransmission–variations on the theme
1998
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles
1983
A Labile Phosphodiester Bond at the Ligation Junction in a Circular Intervening Sequence RNA
1984 StandoutScienceNobel
Neurotransmitter Transporters in the Central Nervous System
1999
Release of the predicted calcitonin gene-related peptide from cultured rat trigeminal ganglion cells
1984 Nature
Organization of the neural cell adhesion molecule (N-CAM) gene: alternative exon usage as the basis for different membrane-associated domains.
1987 Nobel
Brain Peptides: What, Where, And Why?
1983 Science
The Tetrahymena ribozyme acts like an RNA restriction endonuclease
1986 StandoutNatureNobel
Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters.
1994
Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor
1983 Nature
Uptake of Glutamate into Synaptic Vesicles by an Inorganic Phosphate Transporter
2000 Science
Isolation and sequence of a cDNA clone encoding the 31-kDa subunit of bovine kidney vacuolar H+-ATPase.
1988
Expression of functional human interleukin-2 receptor in mouse T cells by cDNA transfection
1986 StandoutNatureNobel
Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters
2008 StandoutNobel
Alternative 5′ exons in c-abl mRNA
1986 Nobel
Synaptically Released Glutamate Does Not Overwhelm Transporters on Hippocampal Astrocytes During High-Frequency Stimulation
2000
Distinct patterns of expression of two VAMP genes within the rat brain
1990
Site-specific polyadenylation in a cell-free reaction
1984
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
Two prohormones for gastrin-releasing peptide are encoded by two mRNAs differing by 19 nucleotides.
1986
The memory gene dunce+ encodes a remarkable set of RNAs with internal heterogeneity.
1986
Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells
1984 StandoutNature
Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor
1983 Nature
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Nucleotide sequence of cloned cDNA encoding bovine arginine vasopressin–neurophysin II precursor
1982 Nature
Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain.
1992
c-erbB activation in ALV-induced erythroblastosis: novel RNA processing and promoter insertion result in expression of an amino-truncated EGF receptor
1985
Human transforming growth factor-α: Precursor structure and expression in E. coli
1984
A novel mechanism of alternative RNA splicing for the developmentally regulated generation of troponin T isoforms from a single gene
1984
The Mating of a Fly
1994 StandoutScienceNobel
Ion Binding and Permeation at the GABA Transporter GAT1
1996
Partial nucleotide sequence of human calcitonin precursor mRNA identifies flanking cryptic peptides
1982 Nature
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells
1985 StandoutNature
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin
1984 Nature
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
1985 StandoutNatureNobel
Only one of the charged amino acids located in the transmembrane alpha-helices of the gamma-aminobutyric acid transporter (subtype A) is essential for its activity.
1993
Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
1995
β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function
1990 StandoutScienceNobel
Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor
1985 StandoutScienceNobel
Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes
1986 StandoutNatureNobel
Works of Susan Amara being referenced
Sulfhydryl modification of V449C in the glutamate transporter EAAT1 abolishes substrate transport but not the substrate-gated anion conductance
2001
Dopamine transporter–mediated conductances increase excitability of midbrain dopamine neurons
2002
Mouse Excitatory Amino Acid Transporter EAAT2: Isolation, Characterization, and Proximity to Neuroexcitability Loci on Mouse Chromosome 2
1994
Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor
2000
A Hydrophobic Domain in Glutamate Transporters Forms an Extracellular Helix Associated with the Permeation Pathway for Substrates
2002
Arachidonic acid elicits a substrate-gated proton current associated with the glutamate transporter EAAT4
1998
A Reentrant Loop Domain in the Glutamate Carrier EAAT1 Participates in Substrate Binding and Translocation
1998
A Model for the Topology of Excitatory Amino Acid Transporters Determined by the Extracellular Accessibility of Substituted Cysteines
2000
Kinetics of a human glutamate transporter
1995
Neurotransmitter transporters: three distinct gene families
1993
Taql RFLP at norepinephrine transporter protein (NET) locus
1993
Ion fluxes associated with excitatory amino acid transport
1995
The Antidepressant-Sensitive Dopamine Transporter inDrosophila melanogaster: A Primordial Carrier for Catecholamines
2001
Differential Modulation of Human Glutamate Transporter Subtypes by Arachidonic Acid
1995
Neurotransmitter Transporters: Recent Progress
1993
Sodium-dependent neurotransmitter reuptake systems
1991
Functional expression and CNS distribution of a β-alanine-sensitive neuronal GABA transporter
1992
Excitatory amino acid transporters: keeping up with glutamate
2002
Assignment of the norepinephrine transporter protein (NET1) locusto chromosome 16
1993
Channels in transporters
1996
Neurotransmitter transporters as molecular targets for addictive drugs
1998
N‐Linked Oligosaccharides Are Required for Cell Surface Expression of the Norepinephrine Transporter but Do Not Influence Substrate or Inhibitor Recognition
1996
An excitatory amino-acid transporter with properties of a ligand-gated chloride channel
1995 Nature
Vaccinia-T7 RNA polymerase expression system: Evaluation for the expression cloning of plasma membrane transporters
1991
Expression cloning of a cocaine-and antidepressant-sensitive human noradrenaline transporter
1991 Nature
Multiple Ionic Conductances of the Human Dopamine Transporter: The Actions of Dopamine and Psychostimulants
1997
Activation of Protein Kinase C Inhibits Uptake, Currents and Binding Associated with the Human Dopamine Transporter Expressed in Xenopus Oocytes
1997
Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing
1983 StandoutNature
Chimeric dopamine-norepinephrine transporters delineate structural domains influencing selectivity for catecholamines and 1-methyl-4-phenylpyridinium.
1994
Regulated Trafficking of the Human Dopamine Transporter
1999
Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products
1982 StandoutNature
Calcitonin/Calcitonin Gene-Related Peptide Transcription Unit: Tissue-Specific Expression Involves Selective Use of Alternative Polyadenylation Sites
1984
Stimulation of noradrenergic sympathetic outflow by calcitonin gene-related peptide
1983 Nature
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.
1984
The Multiple LIM Domain-Containing Adaptor Protein Hic-5 Synaptically Colocalizes and Interacts with the Dopamine Transporter
2002
Alternative RNA Processing: Determining Neuronal Phenotype
1984 Science
Excitatory Amino Acid Transporters of the Salamander Retina: Identification, Localization, and Function
1998
Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance
1997
Expression of neurotransmitter transport from rat brain mRNA in Xenopus laevis oocytes.
1988
Cloning and expression of a human neutral amino acid transporter with structural similarity to the glutamate transporter gene family
1993
Stable expression of a neuronal gamma-aminobutyric acid transporter, GAT-3, in mammalian cells demonstrates unique pharmacological properties and ion dependence.
1994
Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex
1994
Structural domains of catecholamine transporter chimeras involved in selective inhibition by antidepressants and psychomotor stimulants.
1995
Cloning and Expression of a Cocaine-Sensitive Rat Dopamine Transporter
1991 Science
Calcitonin mRNA polymorphism: peptide switching associated with alternative RNA splicing events.
1982
Characterization of rat calcitonin mRNA.
1980
Electrogenic uptake of gamma-aminobutyric acid by a cloned transporter expressed in Xenopus oocytes.
1992
Cell-type-specific expression of catecholamine transporters in the rat brain
1994
Expression in Brain of a Messenger RNA Encoding a Novel Neuropeptide Homologous to Calcitonin Gene-Related Peptide
1985 Science