Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
Storage and Release of ATP from Astrocytes in Culture
2003
Astrocytes: biology and pathology
2009 Standout
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
2009 Standout
P2X7 receptors on microglial cells mediate injury to cortical neurons in vitro
2006
Inflammation and Alzheimer's disease
2000 Standout
Inflammatory processes in Alzheimer's disease
2007
Interleukin‐1‐induced neurotoxicity is mediated by glia and requires caspase activation and free radical release
2006
Cytoskeletal pathology in familial cerebral amyloid angiopathy (British type) with non-neuritic amyloid plaque formation
1999
Duration of expression of inducible nitric oxide synthase in glial cells
1994
Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton
1996
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Apoptosis in the nervous system
2000 StandoutNature
P2X7 nucleotide receptor activation enhances IFNγ‐induced type II nitric oxide synthase activity in BV‐2 microglial cells
2003
The physiology and pathophysiology of nitric oxide in the brain
2005
Acute downregulation of Cx43 alters P2Y receptor expression levels in mouse spinal cord astrocytes
2003
Activation of Central Nervous System Inflammatory Pathways by Interferon-Alpha: Relationship to Monoamines and Depression
2008
Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and Microglia
1997 StandoutNobel
Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature
2011
Demonstration of interleukin-1β in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultrastructural level
1993
Inducible nitric oxide synthase (iNOS)-like immunoreactivity in argyrophilic, tau-positive astrocytes in progressive supranuclear palsy
1998
Reactive microgliosis
1999
Molecular dissection of reactive astrogliosis and glial scar formation
2009 Standout
The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia
2004
The Interferon-Inducible Protein Viperin Inhibits Influenza Virus Release by Perturbing Lipid Rafts
2007
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
1994
Nucleotide signalling during inflammation
2014 StandoutNature
Development of biomarkers in multiple sclerosis
2004
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Nitric oxide synthase expression and enzymatic activity in multiple sclerosis
2004
Astrocytes, from brain glue to communication elements: the revolution continues
2005
ATP-induced inhibition of gap junctional communication is enhanced by interleukin-1 β treatment in cultured astrocytes
2004
Indirect evidence for nitric oxide involvement in multiple sclerosis by characterization of circulating antibodies directed against conjugated S-nitrosocysteine
1995
Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription–polymerase chain reaction study
2001
P2X7Receptors Mediate ATP Release and Amplification of Astrocytic Intercellular Ca2+Signaling
2006
Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis
2003
P2Y2 receptors activate neuroprotective mechanisms in astrocytic cells
2004
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
2011 StandoutNature
Adenosine Triphosphate Is Released during Injurious Mechanical Ventilation and Contributes to Lung Edema
2003
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Astrocyte barriers to neurotoxic inflammation
2015
Purinergic receptors modulate MAP kinases and transcription factors that control microglial inflammatory gene expression
2006
Inducible nitric oxide synthase in chronic active multiple sclerosis plaques: distribution, cellular expression and association with myelin damage
2004
Peroxynitrite Mediates Nitric Oxide–Induced Blood–Brain Barrier Damage
2004
Microglia: Intrinsic immuneffector cell of the brain
1995
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
Microglia: a sensor for pathological events in the CNS
1996 Standout
P2X7 receptors in the nervous system
2006
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
P2Y and P2X purinoceptor mediated Ca2+ signalling in glial cell pathology in the central nervous system
2002
Slow Degradation of Aggregates of the Alzheimer's Disease Amyloid β-Protein by Microglial Cells
1997
Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease
1999
A Stochastic Two-Dimensional Model of Intercellular Ca2+ Wave Spread in Glia
2005
Pathophysiology and Therapeutic Potential of Purinergic Signaling
2006
Therapeutic implications of the TLR and VDR partnership
2007
Transgenic mice and cytokine actions in the brain: bridging the gap between structural and functional neuropathology1Published on the World Wide Web on 21 October 1997.1
1998
Glia: listening and talking to the synapse
2001
Molecular mechanisms of microglial activation
1996
Expression of complement C4 and C9 genes by human astrocytes
1998
Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease
1998
The amino-terminus of the amyloid-β protein is critical for the cellular binding and consequent activation of the respiratory burst of human macrophages
1999
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
Cellular Distribution and Functions of P2 Receptor Subtypes in Different Systems
2004
Cytotoxicity of microglia
1993
Tumor Necrosis Factor α Mediates Lipopolysaccharide-Induced Microglial Toxicity to Developing Oligodendrocytes When Astrocytes Are Present
2008
Astrocytes are very sensitive to develop innate immune responses to lipid‐carried short interfering RNA
2008
Interaction of Alzheimer β-amyloid peptide with the human monocytic cell line THP-1 results in a protein kinase C-dependent secretion of tumor necrosis factor-α
1997
Microglial release of nitric oxide by the synergistic action of β-amyloid and IFN-γ
1995
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation
2012
Demyelination: The Role of Reactive Oxygen and Nitrogen Species
1999
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
2003 StandoutNature
Activation of microglia in the brains of humans with heart disease and hypercholesterolemic rabbits
1997
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Localization and Cell Association of C1q in Alzheimer's Disease Brain
1996
Complement Component C1q Modulates the Phagocytosis of Aβ by Microglia
2000
β-Amyloid converts an acute phase injury response to chronic injury responses
1996
Adenosyl Radical: Reagent and Catalyst in Enzyme Reactions
2010
Ceramide activates microglia to enhance the production/secretion of brain‐derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro
2002
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism
1996
Physiology and Pathophysiology of Purinergic Neurotransmission
2007 Standout
Interleukin-1 beta targeted therapy for type 2 diabetes
2009
Dinucleoside polyphosphates and their interaction with other nucleotide signaling pathways
2006
Nucleotide‐mediated calcium signaling in rat cortical astrocytes: Role of P2X and P2Y receptors
2003
The life, death, and replacement of oligodendrocytes in the adult CNS
2008
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
The blood–brain barrier
2016
Nitric oxide pathways in Alzheimer's disease and other neurodegenerative dementias
2004
P2 receptors and neuronal injury
2006
Inflammatory Neurodegeneration Mediated by Nitric Oxide, Glutamate, and Mitochondria
2003
Late-Onset Chronic Inflammatory Encephalopathy in Immune-Competent and Severe Combined Immune-Deficient (SCID) Mice with Astrocyte-Targeted Expression of Tumor Necrosis Factor
1998
Tryptophan degradation in autoimmune diseases
2007
Multiple Sclerosis — The Plaque and Its Pathogenesis
2006
Remyelination is extensive in a subset of multiple sclerosis patients
2006
Connexins, pannexins, innexins: novel roles of “hemi-channels”
2008
The role of nitric oxide in multiple sclerosis
2002
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
Relevance of protein nitration in brain injury: a key pathophysiological mechanism in neurodegenerative, autoimmune, or inflammatory CNS diseases and stroke
2003
The Inflammasomes
2010 Standout
Perturbations in calcium‐mediated signal transduction in microglia from Alzheimer's disease patients
2005
Cross‐talk among epidermal growth factor, Ap5A, and nucleotide receptors causing enhanced ATP Ca2+ signaling involves extracellular kinase activation in cerebellar astrocytes
2005
Nitric Oxide Production and Neurotoxicity Mediated by Activated Microglia from Human versus Mouse Brain
1994
Inflammatory mechanisms in Alzheimer's disease
1994
The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases
1995
Inhibition of Posttraumatic Microglial Proliferation in a Genetic Model of Macrophage Colony‐Stimulating Factor Deficiency in the Mouse
1994
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Central neuron–glial and glial–glial interactions following axon injury
1998
Local Neuroinflammation and the Progression of Alzheimer's Disease
2002
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Complement and cytokine gene expression in cultured microglia derived from postmortem human brains
1995
Expression and Regulation of Cyclooxygenase‐2 in Rat Microglia
1997
Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation
2006
Microglial activation induced by factor(s) contained in sera from Alzheimer-related ApoE genotypes
1998
Intracellular Zinc Release and ERK Phosphorylation Are Required Upstream of 12-Lipoxygenase Activation in Peroxynitrite Toxicity to Mature Rat Oligodendrocytes
2006
P2X7 receptors: Properties and relevance to CNS function
2006
Induction of nitric oxide synthase in demyelinating regions of multiple sclerosis brains
1994
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
Suppression of Aβ-induced monocyte neurotoxicity by antiinflammatory compounds
1997
Tumour necrosis factor alpha inhibits purinergic calcium signalling in blood–brain barrier endothelial cells
2003
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System
1996
Purinergic signalling and disorders of the central nervous system
2008
Nitric oxide neurotoxicity in neurodegenerative diseases
2004
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration
2003
Serum cytokine levels in patients with Alzheimer's disease
1994
An activity in rat tissues that modifies nitrotyrosine-containing proteins
1998 StandoutNobel
Propagation of Intercellular Calcium Waves in Retinal Astrocytes and Müller Cells
2001
Molecular Physiology of P2X Receptors
2002 Standout
Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.
1995
Expression and regulation of brain metallothionein
1995
MRI demonstrates glutamine antagonist-mediated reversal of cerebral malaria pathology in mice
2018
INFLAMMATION AND ALZHEIMERS DISEASE
2000
A Century of Alzheimer's Disease
2006 StandoutScience
The potential role of nitric oxide in multiple sclerosis
1998
The effects of a novel NSAID on chronic neuroinflammation are age dependent☆
1999
Purinergic receptors activating rapid intracellular Ca2+ increases in microglia
2005
ATP Mediates Calcium Signaling Between Astrocytes and Microglial Cells: Modulation by IFN-γ
2001
IMMUNOLOGY OF MULTIPLE SCLEROSIS
2005 Standout
MICROGLIA AS MEDIATORS OF INFLAMMATORY AND DEGENERATIVE DISEASES
1999
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
NITRIC OXIDE AND MACROPHAGE FUNCTION
1997 Standout
Role of Glycosylation in Development
2004
Structural and functional evidence for microglial expression of C1qRP, the C1q receptor that enhances phagocytosis
2000
P2X7 receptors exert a permissive role on the activation of release-enhancing presynaptic α7 nicotinic receptors co-existing on rat neocortex glutamatergic terminals
2006
Oligodendrocyte-specific expression and autoantigenicity of transaldolase in multiple sclerosis.
1994
Fluorescent Sensors for Zn2+Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution
2001 StandoutNobel
Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis.
1995
Inducible Nitric Oxide Synthase and Nitrotyrosine Are Found in Monocytes/Macrophages and/or Astrocytes in Acute, but Not in Chronic, Multiple Sclerosis
1998
Transforming growth factor beta in Alzheimer's disease
1994
The P2X7 Receptor: A Key Player in IL-1 Processing and Release
2006
Imaging the glycome
2008 StandoutNobel
Astrocyte Ca 2+ waves trigger responses in microglial cells in brain slices
2001
Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen-presenting cells
1994
Visualization of Myelin Basic Protein (Mbp) T Cell Epitopes in Multiple Sclerosis Lesions Using a Monoclonal Antibody Specific for the Human Histocompatibility Leukocyte Antigen (Hla)-Dr2–Mbp 85–99 Complex
2000
Signaling at the Gliovascular Interface
2003
Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death
1996
Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain.
1995
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Non-MHC-Restricted Cell-Mediated Lysis of Human Oligodendrocytes In Vitro: Relation with CD56 Expression
1998
Exacerbation of Experimental Autoimmune Encephalomyelitis in P2X7R−/− Mice: Evidence for Loss of Apoptotic Activity in Lymphocytes
2006
Cerebrospinal fluid and serum nitric oxide metabolites in patients with multiple sclerosis
1998
P2Y2 Receptor Up-Regulation Induced by Guanosine or UTP in Rat Brain Cultured Astrocytes
2006
P2Y1Purinoceptor-Mediated Ca2+Signaling and Ca2+Wave Propagation in Dorsal Spinal Cord Astrocytes
2000
Chemical Glycoproteomics
2016 StandoutNobel
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of Sunhee C. Lee being referenced
The cytokine IL‐1β transiently enhances P2X7 receptor expression and function in human astrocytes
2004
Adhesion molecules on endothelial cells in the central nervous system: An emerging area in the neuroimmunology of multiple sclerosis
1990
Interferon‐β activates multiple signaling cascades in primary human microglia
2002
Selective inhibition of human glial inducible nitric oxide synthase by interferon‐β: Implications for multiple sclerosis
1998
Cytoskeletal Alterations in Human Fetal Astrocytes Induced by Interleukin‐1β
1994
Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ
1993
Inducible nitric oxide synthase expression is selectively induced in astrocytes isolated from adult human brain
1998
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
1993
Cytokines: Powerful Regulators of Glial Cell Activation
2003
Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
2002
Multiple Sclerosis: A Role for Astroglia in Active Demyelination Suggested by Class II MHC Expression and Ultrastructural Study
1990
Reduced cerebral blood flow and N-acetyl aspartate in a murine model of cerebral malaria
2005
A novel action of minocycline: Inhibition of human immunodeficiency virus type 1 infection in microglia
2004
Multiple sclerosis: Oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules
1989
IL‐1‐regulated responses in astrocytes: Relevance to injury and recovery
2004
Expression of inducible nitric oxide synthase, interleukin-1 and caspase-1 in HIV-1 encephalitis
2001
IL-1β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels
1999
IL-1β Regulates Blood-Brain Barrier Permeability via Reactivation of the Hypoxia-Angiogenesis Program
2006
Extracellular Nucleotides Differentially Regulate Interleukin-1β Signaling in Primary Human Astrocytes: Implications for Inflammatory Gene Expression
2001
Differential induction of chemokines in human microglia by type i and ii interferons
2000
Expression of inducible nitric oxide synthase in rat pulmonary Cryptococcus neoformans granulomas.
1996
IFNs Are Critical Regulators of IL-1 Receptor Antagonist and IL-1 Expression in Human Microglia
1998
Expression of Inducible Nitric Oxide Synthase and Nitrotyrosine in Multiple Sclerosis Lesions
2001
Macrophage colony-stimulating factor mediates astrocyte-induced microglial ramification in human fetal central nervous system culture.
1994
Productive infection of human fetal microglia by HIV-1.
1993
The Cytokine IL-1β Activates IFN Response Factor 3 in Human Fetal Astrocytes in Culture
2005
TLR3 Ligation Activates an Antiviral Response in Human Fetal Astrocytes: A Role for Viperin/cig5
2006
Neuronal death in cytokine-activated primary human brain cell culture: role of tumor necrosis factor-?
1999