Standout Papers
Citation Impact
Citing Papers
The human splicing code reveals new insights into the genetic determinants of disease
2014 Science
STAR: ultrafast universal RNA-seq aligner
2012 Standout
Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing
2016 Science
Humanized Foxp2 accelerates learning by enhancing transitions from declarative to procedural performance
2014 StandoutNobel
Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target
2011
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Dropout: a simple way to prevent neural networks from overfitting
2014 StandoutNobel
MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells
2015
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
High-efficiency RNA cloning enables accurate quantification of miRNA expression by deep sequencing
2013
The miR-17/92 cluster: a comprehensive update on its genomics, genetics, functions and increasingly important and numerous roles in health and disease
2013
Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites
2010
FMRP targets distinct mRNA sequence elements to regulate protein expression
2012 Nature
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism
2014
Differential expression analysis for sequence count data
2010 Standout
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Fmrp targets or not: long, highly brain-expressed genes tend to be implicated in autism and brain disorders
2015
Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes
2011 Standout
MicroRNA‐142 controls thymocyte proliferation
2017
The biological functions of miRNAs: lessons from in vivo studies
2014
A biophysical miRNA-mRNA interaction model infers canonical and noncanonical targets
2013
Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
2016
irCLIP platform for efficient characterization of protein–RNA interactions
2016
PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
2010
The evolution of evolvability in microRNA target sites in vertebrates
2013
Differential analysis of gene regulation at transcript resolution with RNA-seq
2012 Standout
The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs
2013
Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis
2014
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Understanding the transcriptome through RNA structure
2011
MicroRNA target site identification by integrating sequence and binding information
2013
The genomic landscape of Neanderthal ancestry in present-day humans
2014 StandoutNatureNobel
RNA-based recognition and targeting: sowing the seeds of specificity
2017 StandoutNobel
EBV and human microRNAs co‐target oncogenic and apoptotic viral and human genes during latency
2012
Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges
2013
miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions
2013
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
The Centrality of RNA
2009
Identification and consequences of miRNA–target interactions — beyond repression of gene expression
2014
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
LIN28B promotes growth and tumorigenesis of the intestinal epithelium via Let-7
2013
A Combinatorial Amino Acid Code for RNA Recognition by Pentatricopeptide Repeat Proteins
2012
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
2010
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Viral crosslinking and solid-phase purification enables discovery of ribonucleoprotein complexes on incoming RNA virus genomes
2020
Global mapping of miRNA-target interactions in cattle (Bos taurus)
2017 StandoutNobel
Mapping in vivo protein-RNA interactions at single-nucleotide resolution from HITS-CLIP data
2011
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades
2011 Standout
RNA-binding proteins in neurodegeneration: Seq and you shall receive
2015
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
General rules for functional microRNA targeting
2016
Metazoan MicroRNAs
2018 Standout
A spectral approach integrating functional genomic annotations for coding and noncoding variants
2016
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition
2014
A role for microRNAs in the Drosophila circadian clock
2009 StandoutNobel
Genomic era analyses of RNA secondary structure and RNA-binding proteins reveal their significance to post-transcriptional regulation in plants
2013
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210
2014
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Endogenous miRNA Sponge lincRNA-RoR Regulates Oct4, Nanog, and Sox2 in Human Embryonic Stem Cell Self-Renewal
2013
RNA and Disease
2009
Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs
2015
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
2012 Standout
A Broad RNA Virus Survey Reveals Both miRNA Dependence and Functional Sequestration
2016 StandoutNobel
Rescue of Fragile X Syndrome Neurons by DNA Methylation Editing of the FMR1 Gene
2018
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
LIN28A Is a Suppressor of ER-Associated Translation in Embryonic Stem Cells
2012
A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins
2011
Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
2012
Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting
2012
Competition between target sites of regulators shapes post-transcriptional gene regulation
2014
Insights into RNA structure and function from genome-wide studies
2014 StandoutNobel
Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB
2009 Nobel
Protein-RNA networks revealed through covalent RNA marks
2015
Desperately seeking microRNA targets
2010
Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
2010
TDP-43 high throughput screening analyses in neurodegeneration: Advantages and pitfalls
2013
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Protein–RNA interactions: new genomic technologies and perspectives
2012
Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer
2017 StandoutNobel
Altered Neuronal and Circuit Excitability in Fragile X Syndrome
2015
Unambiguous Identification of miRNA:Target Site Interactions by Different Types of Ligation Reactions
2014
RNA-binding proteins in human genetic disease
2020
Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver
2013
Deep learning
2015 StandoutNatureNobel
Pre-mRNA splicing: where and when in the nucleus
2011
Genome-wide Analysis of Alternative Pre-mRNA Splicing and RNA-Binding Specificities of the Drosophila hnRNP A/B Family Members
2009
Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
2009 Nature
HITS‐CLIP: panoramic views of protein–RNA regulation in living cells
2010
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types
2014
An RNA-centric dissection of host complexes controlling flavivirus infection
2019 StandoutNobel
CLIP: Construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo
2009
Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation
2013
Endogenous microRNA sponges: evidence and controversy
2016 Standout
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
2010 Standout
Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132
2010
Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
2013
Novel Primate miRNAs Coevolved with Ancient Target Genes in Germinal Zone-Specific Expression Patterns
2014
Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes
2014
starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data
2010
Two new and distinct roles for Drosophila Argonaute-2 in the nucleus: alternative pre-mRNA splicing and transcriptional repression
2013
Landscape and variation of RNA secondary structure across the human transcriptome
2014 Nature
N6-methyladenosine marks primary microRNAs for processing
2015 Nature
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Context-dependent functions of specific microRNAs in neuronal development
2010
Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain
2012
The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts
2012
Experimental strategies for microRNA target identification
2011
An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma
2011
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Development of micro RNA therapeutics is coming of age
2014
New perspectives on the diversification of theRNA interference system: insights from comparative genomics and smallRNA sequencing
2013
Subcellular mRNA Localization in Animal Cells and Why It Matters
2009 Science
Genome Regulation by Long Noncoding RNAs
2012 Standout
Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas
2012
Bayesian prediction of tissue-regulated splicing using RNA sequence and cellular context
2011
Multiplexed RNA structure characterization with selective 2′-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq)
2011 StandoutNobel
2013
Cancer-associated regulation of alternative splicing
2009
Argonaute High-Throughput Sequencing of RNAs Isolated by Cross-Linking Immunoprecipitation Reveals a Snapshot of miRNA Gene Regulation in the Mammalian Retina
2014
Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals
2016 StandoutScienceNobel
Predicting effective microRNA target sites in mammalian mRNAs
2015 Standout
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Integrative Modeling Defines the Nova Splicing-Regulatory Network and Its Combinatorial Controls
2010 Science
Demystifying the nuclear function of Argonaute proteins
2014
Conserved microRNA targeting in Drosophila is as widespread in coding regions as in 3′UTRs
2010
Analysis of CLIP and iCLIP methods for nucleotide-resolution studies of protein-RNA interactions
2012
RNA Regulation in Neurologic Disease and Cancer
2010
Learning to Predict miRNA-mRNA Interactions from AGO CLIP Sequencing and CLASH Data
2016
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Methods for comprehensive experimental identification of RNA-protein interactions
2014
MicroRNA-128 Governs Neuronal Excitability and Motor Behavior in Mice
2013 Science
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
2020 StandoutNobel
Works of Sung Wook being referenced
MicroRNA Target Recognition: Insights from Transcriptome-Wide Non-Canonical Interactions
2016
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps
2009 Nature
An alternative mode of microRNA target recognition
2012
HITS-CLIP yields genome-wide insights into brain alternative RNA processing
2008 Nature