Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors
2022 StandoutNobel
Integrative genomic mining for enzyme function to enable engineering of a non-natural biosynthetic pathway
2015 StandoutNobel
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
A system for the continuous directed evolution of biomolecules
2011 Nature
Combinatorial biosynthesis for drug development
2007
A view on drug resistance in cancer
2019 StandoutNature
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Combinatorial biosynthesis of reduced polyketides
2005
The importance of repairing stalled replication forks
2000 Nature
Catalysis, Specificity, and ACP Docking Site of Streptomyces coelicolor Malonyl-CoA:ACP Transacylase
2003
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Novel DNA Polymerases Offer Clues to the Molecular Basis of Mutagenesis
1999
The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites
2005
Biosynthesis of Lovastatin Analogs with a Broadly Specific Acyltransferase
2006
PKD1 Unusual DNA Conformations Are Recognized by Nucleotide Excision Repair
2001
Minimal Methylated Substrate and Extended Substrate Range of Escherichia coli AlkB Protein, a 1-Methyladenine-DNA Dioxygenase
2003 StandoutNobel
Organocatalytic Enantioselective Decarboxylative Aldol Reaction of Malonic Acid Half Thioesters with Aldehydes
2013 StandoutNobel
Targeting cancer with small molecule kinase inhibitors
2008 Standout
Bacterial toxin YafQ is an endoribonuclease that associates with the ribosome and blocks translation elongation through sequence‐specific and frame‐dependent mRNA cleavage
2009
Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord
1994 Standout
Checkpoint activation regulates mutagenic translesion synthesis
2003
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
2002
The bacterial injection kit: Type III secretion systems
2005
fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development
1994 StandoutNobel
Engineering synthetic recursive pathways to generate non-natural small molecules
2012
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity
1993 Standout
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
Importance of Uracil DNA Glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich Bacteria, in Mutation Prevention, Tolerance to Acidified Nitrite, and Endurance in Mouse Macrophages
2003
Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry
2014 StandoutNobel
Regulation of premeiotic S phase and recombination-related double-strand DNA breaks during meiosis in fission yeast
2001 StandoutNobel
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
The type I fatty acid and polyketide synthases: a tale of two megasynthases
2007
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
The Crystal Structure of Yeast Fatty Acid Synthase, a Cellular Machine with Eight Active Sites Working Together
2007 StandoutNobel
Sonic hedgehog mediates the polarizing activity of the ZPA
1993 Standout
Engineering the third wave of biocatalysis
2012 StandoutNature
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
Ribosomal Synthesis of N-Methyl Peptides
2008 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Acute Myeloid Leukemia
2015 Standout
Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF4 Hub
2017 StandoutNobel
2013
Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila
1992
The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.
1992
Quality Control by DNA Repair
1999 StandoutScienceNobel
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
2018 StandoutNobel
THE SOS RESPONSE: Recent Insights into umuDC-Dependent Mutagenesis and DNA Damage Tolerance
2000
Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF4)‐Derived Connective Hubs for Bioconjugation to DNA and Proteins
2019 StandoutNobel
Synthetic Biology for Synthetic Chemistry
2008
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Enzymatic Chemistry of Cyclopropane, Epoxide, and Aziridine Biosynthesis
2011
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
Stochastic Gene Expression in a Single Cell
2002 StandoutScience
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Diverse Functional Roles of Reactive Cysteines
2012
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Genetic requirements for mycobacterial survival during infection
2003 Standout
The resurgence of covalent drugs
2011
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry
2008
Palladium‐Catalyzed Fluorosulfonylvinylation of Organic Iodides
2017 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein
1996 StandoutScience
RecA-Dependent Recovery of Arrested DNA Replication Forks
2003
High-fidelity in vivo replication of DNA base shape mimics without Watson–Crick hydrogen bonds
2003
A New Portal to SuFEx Click Chemistry: A Stable Fluorosulfuryl Imidazolium Salt Emerging as an “F−SO2+” Donor of Unprecedented Reactivity, Selectivity, and Scope
2017 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Works of Sumati Murli being referenced
Identification of Nuclear Export Inhibitors with Potent Anticancer Activity In vivo
2009
The embryonically active gene, unkempt, of Drosophila encodes a Cys3His finger protein.
1992
Role of tyrosine kinases and the tyrosine phosphatase SptP in the interaction of Salmonella with host cells
2001
Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production
2003
A model for a umuDC -dependent prokaryotic DNA damage checkpoint
1999
umuDC-dnaQ Interaction and Its Implications for Cell Cycle Regulation and SOS Mutagenesis in Escherichia coli
2001
6-Deoxyerythronolide B Analogue Production in Escherichia coli through Metabolic Pathway Engineering
2003
Alteration of the Substrate Specificity of a Modular Polyketide Synthase Acyltransferase Domain through Site-Specific Mutations
2001
A Role for the umuDC Gene Products of Escherichia coli in Increasing Resistance to DNA Damage in Stationary Phase by Inhibiting the Transition to Exponential Growth
2000
Chemobiosynthesis of Novel 6-Deoxyerythronolide B Analogues by Mutation of the Loading Module of 6-Deoxyerythronolide B Synthase 1
2005
Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides
2006
A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases
2003