Citation Impact
Citing Papers
HRD4/NPL4 Is Required for the Proteasomal Processing of Ubiquitinated ER Proteins
2001
Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit
2001 StandoutScienceNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
The ATP-dependent HslVU protease from Escherichia coli is a four-ring structure resembling the proteasome
1997
X-ray Snapshots of Peptide Processing in Mutants of Tricorn-interacting Factor F1 from Thermoplasma acidophilum
2005 Nobel
Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping
1995 StandoutScienceNobel
The CtsR regulator of stress response is active as a dimer and specifically degraded in vivo at 37°C
2000
Improved molecular replacement by density- and energy-guided protein structure optimization
2011 StandoutNatureNobel
Destabilization of the complete protein secondary structure on binding to the chaperone GroEL
1994 StandoutNatureNobel
Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein
1994 StandoutNatureNobel
The Janus Face of the Archaeal Cdc48/p97 Homologue VAT: Protein Folding versus Unfolding
1999
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
2000
Clp-mediated proteolysis in Gram-positive bacteria is autoregulated by the stability of a repressor
2001
Getting in and out of the proteasome
2000
A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome
2001
A subfamily of stress proteins facilitates translocation of secretory and mitochondrial precursor polypeptides
1988 StandoutNatureNobel
The base of the proteasome regulatory particle exhibits chaperone-like activity
1999
Rapid Degradation of an Abnormal Protein in Escherichia coli Proceeds through Repeated Cycles of Association with GroEL
1999
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination
2000
CtsR, a novel regulator of stress and heat shock response, controls clp and molecular chaperone gene expression in Gram‐positive bacteria
1999
ClpE, a novel type of HSP100 ATPase, is part of the CtsR heat shock regulon of Bacillus subtilis
1999
ATP-Dependent Proteases Degrade Their Substrates by Processively Unraveling Them from the Degradation Signal
2001
The Molecular Chaperone DnaJ Is Required for the Degradation of a Soluble Abnormal Protein in Escherichia coli
2001
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Global unfolding of a substrate protein by the Hsp100 chaperone ClpA
1999 Nature
Crystal structure of Thermus aquaticus DNA polymerase
1995 StandoutNatureNobel
ATP Hydrolysis by the Proteasome Regulatory Complex PAN Serves Multiple Functions in Protein Degradation
2003
Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes
2003
An Archaebacterial ATPase, Homologous to ATPases in the Eukaryotic 26 S Proteasome, Activates Protein Breakdown by 20 S Proteasomes
1999
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Sculpting the Proteome with AAA+ Proteases and Disassembly Machines
2004
Hsp104, Hsp70, and Hsp40
1998
Protein degradation and protection against misfolded or damaged proteins
2003 StandoutNature
Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex
1991 StandoutNatureNobel
Protein folding in the cell
1992 StandoutNature
Proteins Are Unfolded on the Surface of the ATPase Ring before Transport into the Proteasome
2001
GroEL-Mediated Protein Folding: Making the Impossible, Possible
2006
Solution structure of a minor and transiently formed state of a T4 lysozyme mutant
2011 StandoutNatureNobel
Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling
2001
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
1998
The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome
2000
NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer
1999
The immune response of Drosophila
2003 StandoutNatureNobel
Degradation of Ornithine Decarboxylase by the 26S Proteasome
2000
Structure of Taq polymerase with DNA at the polymerase active site
1996 StandoutNatureNobel
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
1998
Characterization of ARC, a divergent member of the AAA ATPase family from Rhodococcus erythropolis
1998
Programmed population control by cell–cell communication and regulated killing
2004 StandoutNatureNobel
Organization and evolution of bacterial and bacteriophage primase-helicase systems
1992
Mechanism of folding chamber closure in a group II chaperonin
2010 StandoutNatureNobel
Recognition of the polyubiquitin proteolytic signal
2000
CHIP Is a U-box-dependent E3 Ubiquitin Ligase
2001
RGS4 Is Arginylated and Degraded by the N-end Rule Pathway in Vitro
2000
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Self-compartmentalizing proteases
1997
The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair
1999
The ubiquitin system
1997
Recognition of Misfolding Proteins by PA700, the Regulatory Subcomplex of the 26 S Proteasome
2000
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
AAA+ superfamily ATPases: common structure–diverse function
2001
Proteasome function is dispensable under normal but not under heat shock conditions in Thermoplasma acidophilum
1998
A Subcomplex of the Proteasome Regulatory Particle Required for Ubiquitin-Conjugate Degradation and Related to the COP9-Signalosome and eIF3
1998
Specificity of recognition sequence forEscherichia coli primase
1991
Proteasomes and other self-compartmentalizing proteases in prokaryotes
1999
Uncoupling retro‐translocation and degradation in the ER‐associated degradation of a soluble protein
2004
Modes of regulation of ubiquitin-mediated protein degradation
2000 StandoutNobel
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
2000
Activation of the Drosophila NF‐κB factor Relish by rapid endoproteolytic cleavage
2000
Ordered Assembly of Nucleoprotein Structures at the Bacteriophage λ Replication Origin during the Initiation of DNA Replication
1989
Cloning and characterization of the Escherichia coli chromosomal region surrounding the dnaG gene, with a correlated physical and genetic map of dnaG generated via transposon Tn5 mutagenesis
1982
The Single-Stranded DNA Phages
1975
ATP utilization by rep protein in the catalytic separation of DNA strands at a replicating fork.
1978
Nucleotide sequences of the separate origins of synthesis of bacteriophage G4 viral and complementary DNA strands.
1978
Specialized Nucleoprotein Structures at the Origin of Replication of Bacteriophage λ
1989
Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains.
1978
Initiation of lambda DNA replication with purified host- and bacteriophage-encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins.
1989
The Regulatory Particle of the Saccharomyces cerevisiae Proteasome
1998
The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis
1999 Standout
Gene cloning for the isolation of enzymes of membrane lipid synthesis: phosphatidylserine synthase overproduction in Escherichia coli.
1977
Domains of Escherichia coli primase: functional activity of a 47-kDa N-terminal proteolytic fragment.
1994 StandoutNobel
Bacteriophage T7 deoxyribonucleic acid replication invitro. Bacteriophage T7 DNA polymerase: an an emzyme composed of phage- and host-specific subunits.
1975 StandoutNobel
McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR
2009 StandoutScienceNobel
Post-incision steps of nucleotide excision repair in Escherichia coli. Disassembly of the UvrBC-DNA complex by helicase II and DNA polymerase I.
1992 StandoutNobel
DNA polymerase III holoenzyme of Escherichia coli. Purification and resolution into subunits.
1977
Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning
1977 StandoutScienceNobel
Membrane phospholipid synthesis in Escherichia coli. Cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyl/transferase.
1980 StandoutNobel
Isolation and Function of the Gene A Initiator of Bacteriophage ϕX 174, A Highly Specific DNA Endonuclease
1974
Ten proteins required for conversion of phiX174 single-stranded DNA to duplex form in vitro. Resolution and reconstitution.
1975 StandoutNobel
An Escherichia coli mutant defective in single-strand binding protein is defective in DNA replication.
1979
Initiation of DNA replication by the Escherichia coli dnaG protein: evidence that tertiary structure is involved.
1980
Biochemical and Physical Properties of theMethanococcus jannaschii20S Proteasome and PAN, a Homolog of the ATPase (Rpt) Subunits of the Eucaryal 26S Proteasome
2000
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
DNA sequencing with chain-terminating inhibitors
1977 StandoutNobel
Use of site-specific recombination as a probe of DNA structure and metabolism in vivo
1987
Major heat shock gene of Drosophila and the Escherichia coli heat-inducible dnaK gene are homologous.
1984
Site-specific initiation of a DNA fragment.
1978
A general priming system employing only dnaB protein and primase for DNA replication.
1979
Quality Control Mechanisms During Translation
1999 Science
A multienzyme system for priming the replication of phiX174 viral DNA.
1978
A multicomponent system that degrades proteins conjugated to ubiquitin. Resolution of factors and evidence for ATP-dependent complex formation.
1988 StandoutNobel
Role of the Escherichia coli DnaK and DnaJ heat shock proteins in the initiation of bacteriophage lambda DNA replication.
1988
Large-scale overproduction and rapid purification of the Escherichia coli ssb gene product. Expression of the ssb gene under .lambda. PL control
1986
Molecular chaperones and the art of recognizing a lost cause
2001
Proteasomes in the archaea: from structure to function
2000
Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans.
1992
UBIQUITIN-DEPENDENT PROTEIN DEGRADATION
1996
Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly
1989 StandoutScienceNobel
Gene K, a new overlapping gene in bacteriophage G4
1978 StandoutNatureNobel
Conditional-lethal mutations that suppress genetic defects in morphogenesis by altering structural proteins.
1975
Addiction Modules and Programmed Cell Death and Antideath in Bacterial Cultures
1999
DNA- and RNA-dependent DNA polymerases
1993 StandoutNobel
DNA Mismatch Correction in a Defined System
1989 StandoutScienceNobel
A New Form of DNA Polymerase III and a Copolymerase Replicate a Long, Single-Stranded Primer-Template
1973 StandoutNobel
Heat Shock Protein-mediated Disassembly of Nucleoprotein Structures Is Required for the Initiation of Bacteriophage λ DNA Replication
1989
A suppressor mutation in the nematode acting on specific alleles of many genes
1978 StandoutNatureNobel
Dis-assembly lines: the proteasome and related ATPase-assisted proteases
2000
Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork.
1994
Deoxyribonucleic acid polymerase III of Escherichia coli. Purification and properties
1975
Purification of complexes of nuclear oncogene p53 with rat and Escherichia coli heat shock proteins: in vitro dissociation of hsc70 and dnaK from murine p53 by ATP.
1988
Folding of Newly Translated Proteins In Vivo: The Role of Molecular Chaperones
2001
A Holoenzyme Form of Deoxyribonucleic Acid Polymerase III
1974
Chaperone rings in protein folding and degradation
1999
Identification of two Escherichia coli factor Y effector sites near the origins of replication of the plasmids (ColE1 and pBR322.
1980
The deoxyribonucleic acid unwinding protein of Escherichia coli. Properties and functions in replication.
1975
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system.
1983
A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein.
1989
Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase
1985 StandoutNatureNobel
Recalibrated linkage map of Escherichia coli K-12
1976
Mechanism of dnaB protein action. IV. General priming of DNA replication by dnaB protein and primase compared with RNA polymerase.
1981
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form.
1975
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Nucleotide sequence of bacteriophage G4 DNA
1978 StandoutNature
The Axial Channel of the Proteasome Core Particle Is Gated by the Rpt2 ATPase and Controls Both Substrate Entry and Product Release
2001
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Amplification of single-strand DNA binding protein in Escherichis coli
1980 StandoutNobel
Conversion of the M13 Viral Single Strand to the Double-stranded Replicative Forms by Purified Proteins
1974
Purification and Properties of the Escherichia coli Deoxyribonucleic Acid-unwinding Protein
1974
Nucleoprotein structures initiating DNA replication, transcription, and site-specific recombination.
1990
Quantitative NMR spectroscopy of supramolecular complexes: Dynamic side pores in ClpP are important for product release
2005
Cloning of the Escherichia coli dnaZX region and identification of its products
1983
Nucleotide sequence of bacteriophage φX174 DNA
1977 StandoutNatureNobel
Multienzyme Systems of DNA Replication
1974 StandoutScienceNobel
Works of Sue Wickner being referenced
ClpAP and ClpXP degrade proteins with tags located in the interior of the primary sequence
2002
Lambda DNA Replication
1983
Clp ATPases and their role in protein unfolding and degradation
2001
Substrate Recognition by the ClpA Chaperone Component of ClpAP Protease
2000
Regulatory Subunits of Energy-Dependent Proteases
1997
Function of DnaJ and DnaK as chaperones in origin-specific DNA binding by RepA
1991 Nature
The RssB response regulator directly targets ςS for degradation by ClpXP
2001
Protein quality control: triage by chaperones and proteases.
1997
Mini-P1 plasmid replication: The autoregulation-sequestration paradox
1988
Concurrent Chaperone and Protease Activities of ClpAP and the Requirement for the N-terminal ClpA ATP Binding Site for Chaperone Activity
1999
Posttranslational Quality Control: Folding, Refolding, and Degrading Proteins
1999 Science
Here’s the hook: Similar substrate binding sites in the chaperone domains of Clp and Lon
1999
Translocation pathway of protein substrates in ClpAP protease
2001
DNA dependent RNA polymerase catalyzed synthesis of polyribonucleotide chains covalently linked to DNA
1972
Specialized nucleoprotein structures at the origin of replication of bacteriophage lambda: localized unwinding of duplex DNA by a six-protein reaction.
1986
The role of the ClpA chaperone in proteolysis by ClpAP
1998
Mechanism of protein remodeling by ClpA chaperone
1997
Overlapping recognition determinants within the ssrA degradation tag allow modulation of proteolysis
2001
Studies on In Vitro DNA Synthesis Isolation of dna B Gene Product from Escherichia coli
1973
Characterization of the DNA binding domain of bacteriophage lambda O protein.
1986
DNA Replication Proteins of Escherichia Coli
1978
Involvement of Two Protein Factors and ATP in In Vitro DNA Synthesis Catalyzed by DNA Polymerase III of Escherichia coli
1974
Conversion of ϕX174 Viral DNA to Double-Stranded Form by Purified Escherichia coli Proteins
1974
Overproduction of dna gene products by Escherichia coli strains carrying hybrid co1E1 plasmids
1976
Studies on In Vitro DNA Synthesis Purification of the dna G Gene Product from Escherichia coli
1973
Oligonucleotide synthesis by Escherichia coli dnaG primase in conjunction with phage P22 gene 12 protein.
1984
Studies on In Vitro DNA Synthesis Purification of dna C Gene Product Containing dna D Activity from Escherichia coli
1973
Involvement of escherichia coli dnaZ gene product in DNA elongation in vitro.
1976
DNA or RNA priming of bacteriophage G4 DNA synthesis by Escherichia coli dnaG protein.
1977
DNA-dependent ATPase activity associated with phage P22 gene 12 protein.
1984
Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP
2000
Studies on invitro DNA synthesis
1973
Role of the Xis protein of bacteriophage λ in a specific reactive complex at the attR prophage attachment site
1983
Mechanism of DNA elongation catalyzed by Escherichia coli DNA polymerase III, dnaZ protein, and DNA elongation factors I and III.
1976
Association of DNA-dependent and -independent Ribonucleoside Triphosphatase Activities with dnaB Gene Product of Escherichia coli
1974
Association of phiX174 DNA-dependent ATPase activity with an Escherichia coli protein, replication factor Y, required for in vitro synthesis of phiX174 DNA.
1975
Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP
2000
Three Escherichia coli heat shock proteins are required for P1 plasmid DNA replication: formation of an active complex between E. coli DnaJ protein and the P1 initiator protein.
1990
DNA Replication Proteins of Escherichia coli and Phage
1979
A molecular chaperone, ClpA, functions like DnaK and DnaJ.
1994
Conversion of ϕX174 and fd Single-Stranded DNA to Replicative Forms in Extracts of Escherichia coli
1972
Deletion analysis of the DNA sequence required for the in vitro initiation of replication of bacteriophage lambda.
1987
Interaction of Escherichia coli dnaB and dnaC(D) gene products in vitro.
1975