Standout Papers
Citation Impact
Citing Papers
Augmenting neurotransmitter release by enhancing the apparent Ca 2+ affinity of synaptotagmin 1
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
2009 Standout
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Condensation of nonstochiometric DNA/polycation complexes by divalent cations
2006
Virus-Plus-Susceptibility Gene Interaction Determines Crohn's Disease Gene Atg16L1 Phenotypes in Intestine
2010
CTLA4Ig: Bridging the Basic Immunology with Clinical Application
2006
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
2003
Liver Transplantation for Hepatocellular Carcinoma: Expansion of the Tumor Size Limits Does Not Adversely Impact Survival
2001 Standout
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
Ca2+-Dependent Synaptotagmin Binding to SNAP-25 Is Essential for Ca2+-Triggered Exocytosis
2002
TREATMENT WITH THE HUMANIZED CD154-SPECIFIC MONOCLONAL ANTIBODY, hu5C8, PREVENTS ACUTE REJECTION OF PRIMARY SKIN ALLOGRAFTS IN NONHUMAN PRIMATES1
2001
Simultaneous Administration of Adjuvant Donor Bone Marrow in Pancreas Transplant Recipients
1999
The role of the graft in establishing tolerance
2002
Lack of Improvement in Renal Allograft Survival Despite a Marked Decrease in Acute Rejection Rates Over the Most Recent Era
2004 Standout
Immunosuppressants: Cellular and molecular mechanisms of action
1996
A Nonsimultaneous, Extended, Altruistic-Donor Chain
2009 StandoutNobel
Heterologous immunity provides a potent barrier to transplantation tolerance
2003
Regulatory T Cells
2000 StandoutNobel
Angiotensin–Converting Enzyme Inhibition by Enalapril: A Novel Approach to Reduce Ischemia/Reperfusion Damage After Experimental Liver Transplantation
1997
RECIPIENT CELLS EXPRESSING SINGLE DONOR MHC LOCUS PRODUCTS CAN SUBSTITUTE FOR DONOR-SPECIFIC TRANSFUSION IN THE INDUCTION OF TRANSPLANTATION TOLERANCE WHEN PRETREATMENT IS COMBINED WITH ANTI-CD4 MONOCLONAL ANTIBODY
1996
Classification of Surgical Complications
2004 Standout
CD40 Ligation Releases Immature Dendritic Cells from the Control of Regulatory CD4+CD25+ T Cells
2003
p27kip1 functions as an anergy factor inhibiting interleukin 2 transcription and clonal expansion of alloreactive human and mouse helper T lymphocytes
2000
Self-assembly of DNA into nanoscale three-dimensional shapes
2009 StandoutNature
Impact of both donor and recipient strains on cardiac allograft survival after blockade of the CD40-CD154 costimulatory pathway1
2002
Altered responses of regenerating hepatocytes to norepinephrine and transforming growth factor type β
1989
SIX-YEAR CLINICAL EFFECT OF DONOR BONE MARROW INFUSIONS IN RENAL TRANSPLANT PATIENTS1
2001
RANDOMIZED TRIAL OF TACROLIMUS PLUS MYCOPHENOLATE MOFETIL OR AZATHIOPRINE VERSUS CYCLOSPORINE ORAL SOLUTION (MODIFIED) PLUS MYCOPHENOLATE MOFETIL AFTER CADAVERIC KIDNEY TRANSPLANTATION: RESULTS AT 2 YEARS1
2001
The KRN mouse model of inflammatory arthritis
2003
Adaptive Immunity to the Hepatitis C Virus
2010
Renal Transplantation
1994
Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells
2013
Priming of hepatitis C virus-specific cytotoxic t lymphocytes in mice following portal vein injection of a liver-specific plasmid DNA
2000 StandoutNobel
Rituximab as Treatment for Refractory Kidney Transplant Rejection
2004
How regulatory T cells work
2008 Standout
Pathogenesis of chronic viral hepatitis: differential roles of T cells and NK cells
2013
Randomised controlled trial of steroid withdrawal in renal transplant recipients receiving triple immunosuppression
1996 StandoutNobel
MIXED CHIMERISM AS AN APPROACH FOR THE INDUCTION OF TRANSPLANTATION TOLERANCE1
1999
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
LIVING UNRELATED DONORS IN KIDNEY TRANSPLANTS
2000
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
LONG-TERM OUTCOME AND ALLOANTIBODY PRODUCTION IN A NON-MYELOABLATIVE REGIMEN FOR INDUCTION OF RENAL ALLOGRAFT TOLERANCE1
1999
HYPERLIPIDEMIA IN SOLID ORGAN TRANSPLANTATION
1997
Strategies to Improve Long-Term Outcomes after Renal Transplantation
2002 Standout
The function of serotonin within the liver
2008
Clinical Trials of Transplant Tolerance: Slow But Steady Progress
2003
Inositol trisphosphate and calcium signalling
1993 StandoutNature
The role of regulatory T cells in controlling immunologic self-tolerance
2003 StandoutNobel
Regulatory T cells under scrutiny
2003
Revealing the world of RNA interference
2004 StandoutNatureNobel
CD8+ T CELLS CONTRIBUTE TO THE DEVELOPMENT OF TRANSPLANT ARTERIOSCLEROSIS DESPITE CD154 BLOCKADE1
2000
A NOVEL APPROACH TO THE TREATMENT OF CHRONIC ALLOGRAFT NEPHROPATHY1
1997
Effect of Pravastatin on Outcomes after Cardiac Transplantation
1995 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Cyclosporine
1989 Standout
Asialo GM1+ CD8+ T cells play a critical role in costimulation blockade–resistant allograft rejection
1999
CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS
1999
REJECTION RESPONSES TO ALLOGENEIC HEPATOCYTES BY RECONSTITUTED SCID MICE, CD4 KO, AND CD8 KO MICE1,2
2000
Points of control in inflammation
2002 StandoutNature
Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
1999
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Liver Regeneration after Partial Hepatectomy
2009
The Immunobiology of Inductive Anti-CD40L Therapy in Transplantation: Allograft Acceptance is Not Dependent Upon the Deletion of Graft-Reactive T Cells
2002
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
What's in the Pipeline? New Immunosuppressive Drugs in Transplantation
2002
Regulation of DNA polymerase α activity by the α1-adrenergic receptors in proliferatively activated rat liver cells
1991
Immunosuppressive strategies in transplantation
1999
CXCR3 ligands in disease and therapy
2014
RESULTS FROM A HUMAN RENAL ALLOGRAFT TOLERANCE TRIAL EVALUATING THE HUMANIZED CD52-SPECIFIC MONOCLONAL ANTIBODY ALEMTUZUMAB (CAMPATH-1H)
2003
Nondirected Donation of Kidneys from Living Donors
2000
Living unrelated donor kidney transplantation
2000
Autophagy in immunity and inflammation
2011 StandoutNature
CD40L Blockade Prevents Autoimmune Diabetes by Induction of Bitypic NK/DC Regulatory Cells
2002
Delivery of siRNA and siRNA Expression Constructs to Adult Mammals by Hydrodynamic Intravascular Injection
2005
Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells
2005
The plant immune system
2006 StandoutNature
Definition and Classification of Negative Outcomes in Solid Organ Transplantation Application in Liver Transplantation
1994
Tolerance to vascularized organ allografts in large-animal models
1999
Development of Catheter-Based Procedures for Transducing the Isolated Rabbit Liver with Plasmid DNA
2002
Identification of Regulatory T Cells in Tolerated Allografts
2002
CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection
2000
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Critical Role of OX40 in CD28 and CD154-Independent Rejection
2004
Targeting Signal 1 Through CD45RB Synergizes with CD40 Ligand Blockade and Promotes Long Term Engraftment and Tolerance in Stringent Transplant Models
2001
Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance
2000
Cd4+Cd25+ Immune Regulatory Cells Are Required for Induction of Tolerance to Alloantigen via Costimulatory Blockade
2001
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Effector and Memory CTL Differentiation
2006
The complement dependent cytotoxicity (CDC) immune effector mechanism contributes to anti-CD154 induced immunosuppression.
2002
Cutting Edge: CD4+CD25+ Alloantigen-Specific Immunoregulatory Cells That Can Prevent CD8+ T Cell-Mediated Graft Rejection: Implications for Anti-CD154 Immunotherapy
2002
The role of the graft in establishing tolerance
2002
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro
2005 StandoutNobel
Modulation of insulin-like growth factor-II/mannose 6-phosphate receptors and transforming growth factor-beta 1 during liver regeneration.
1991
EARLY ALLOGRAFT DYSFUNCTION AFTER LIVER TRANSPLANTATION
1998
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Glycolipid α-C-galactosylceramide is a distinct inducer of dendritic cell function during innate and adaptive immune responses of mice
2006 StandoutNobel
Liver Regeneration
1997 StandoutScience
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Steroid-free immunosuppression in cyclosporine-treated renal transplant recipients
1993
Why do we reject a graft? Role of indirect allorecognition in graft rejection
1999
Complexities of CD28/B7: CTLA-4 Costimulatory Pathways in Autoimmunity and Transplantation
2001
Alloantigen–induced specific immunological unresponsiveness
2001
The role of peripheral T–cell deletion in transplantation tolerance
2001
Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8+ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner
2000
Hepatocyte growth factor (hepatopoietin A) rapidly increases in plasma before DNA synthesis and liver regeneration stimulated by partial hepatectomy and carbon tetrachloride administration
1991
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle
2010 StandoutNobel
Heterologous immunity provides a potent barrier to transplantation tolerance
2003
Long-term outcome of a prospective trial of steroid withdrawal after kidney transplantation
1999
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury
2007 StandoutNobel
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
The Role of the IL-2 Pathway in Costimulation Blockade-Resistant Rejection of Allografts
2002
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Effect of α-adrenergic blockers on calmodulin association with the nuclear matrix of rat liver cells during proliferative activation
1989
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Contrasting Roles of IL-2 and IL-15 in the Life and Death of Lymphocytes
2001
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
2005 StandoutNobel
Regulatory T Cells Induced by 1α,25-Dihydroxyvitamin D3 and Mycophenolate Mofetil Treatment Mediate Transplantation Tolerance
2001
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Stuart J. Knechtle being referenced
Developmental Exposure to Noninherited Maternal Antigens Induces CD4+ T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance
2007
Transient CD86 Expression on Hepatitis C Virus-Specific CD8+ T Cells in Acute Infection Is Linked to Sufficient IL-2 Signaling
2010
Campath-1H Induction Plus Rapamycin Monotherapy for Renal Transplantation: Results of a Pilot Study
2003
α1-Adrenergic effects and liver regeneration
1987
RISK FACTORS FOR PRIMARY DYSFUNCTION AFTER LIVER TRANSPLANTATION—A MULTIVARIATE ANALYSIS
1993
Inducing unresponsiveness by the use of anti-CD3 immunotoxin, CTLA4-Ig, and anti-CD40 ligand
1999
Elevation of CXCR3-Binding Chemokines in Urine Indicates Acute Renal-Allograft Dysfunction
2004
Knowledge about transplantation tolerance gained in primates
2000
Experience With 500 Simultaneous Pancreas-Kidney Transplants
1998
CD4+CD25+FOXP3+ Regulatory T Cells Increase De Novo in Kidney Transplant Patients After Immunodepletion with Campath-1H
2008
A Controlled, Double-Blind, Randomized Trial of Verapamil and Cyclosporine in Cadaver Renal Transplant Patients
1993
Biologics in organ transplantation
2012
ANALYSIS OF PRIMATE RENAL ALLOGRAFTS AFTER T-CELL DEPLETION WITH ANTI-CD3-CRM91,2
1998
SPLIT TOLERANCE INDUCED BY IMMUNOTOXIN IN A RHESUS KIDNEY ALLOGRAFT MODEL1
1997
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
1999 Standout
Living unrelated renal donation: The University of Wisconsin experience
1998
DETERMINANTS OF GRAFT SURVIVAL AFTER RENAL TRANSPLANTATION1
1996
THE EFFECT OF DONOR AGE, RECIPIENT AGE, AND HLA MATCH ON IMMUNOLOGIC GRAFT SURVIVAL IN CADAVER RENAL TRANSPLANT RECIPIENTS1
1992
A New Look at Blockade of T-cell Costimulation: A Therapeutic Strategy for Long-term Maintenance Immunosuppression
2006
The Use of UW Solution in Clinical Transplantation A 4-year Experience
1992
Expression of Naked Plasmid DNA Injected into the Afferent and Efferent Vessels of Rodent and Dog Livers
1997
FN18-CRM9 IMMUNOTOXIN PROMOTES TOLERANCE IN PRIMATE RENAL ALLOGRAFTS1
1997
INDUCTION OF SPECIFIC TOLERANCE BY INTRATHYMIC INJECTION OF RECIPIENT MUSCLE CELLS TRANSFECTED WITH DONOR CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
1994
Prolongation of Long-Term Kidney Graft Survival by a Simultaneous Liver Transplant: The Liver Does It, and the Heart Does It Too.
2002
Naked DNA delivered intraportally expresses efficiently in hepatocytes.
1996
Primate renal transplants using immunotoxin
1998
PRETRANSPLANT STATUS AND PATIENT SURVIVAL FOLLOWING LIVER TRANSPLANTATION
1995
INDUCTION OF SPECIFIC TOLERANCE BY INTRATHYMIC INJECTION OF RECIPIENT MUSCLE CELLS TRANSFECTED WITH DONOR CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX
1994
Macrophages Driven to a Novel State of Activation Have Anti-Inflammatory Properties in Mice
2008
Treatment with immunotoxin
2001
SUCCESSFUL CONVERSION FROM CONVENTIONAL IMMUNOSUPPRESSION TO ANTI-CD40 LIGAND THERAPY IN A NON-NUMAN PRIMATE MODEL.
2000
CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates
1997
Urine proteomics in kidney transplantation
2013
Hyperlipidemia and transplantation
1992
Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients.
1991
XENOGRAFT SURVIVAL IN TWO SPECIES COMBINATIONS USING TOTAL-LYMPHOID IRRADIATION AND CYCLOSPORINE
1987
Living Related and Unrelated Donors for Kidney Transplantation A 28-Year Experience
1995
TREATMENT OF STEROID RESISTANT REJECTION WITH A NOVEL ANTI B-CELL PREPARATION, RITUXIMAB.
2000
In Vivo transfer of gene encoding soluble MHC class I prolongs heart transplant survival
1993