Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
Hypoxia-Inducible Factor-2α Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer
2008
HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
2001 StandoutScienceNobel
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist
2004 StandoutNobel
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: Assessment of an oral agent that stimulates erythropoietin production
2005 StandoutNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasis
2010
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Redox regulation of the hypoxia-inducible factor
2006
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
2011
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
Hypoxia and gastrointestinal disease
2007
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia
2000 Standout
The Role of Mitochondria in the Regulation of Hypoxia-inducible Factor 1 Expression during Hypoxia
2000
Oxygen sensing and signaling: impact on the regulation of physiologically important genes
1999
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Hypoxia-responsive transcription factors
2005
Mersalyl Is a Novel Inducer of Vascular Endothelial Growth Factor Gene Expression and Hypoxia-Inducible Factor 1 Activity
1998 StandoutNobel
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Regulation of immunity and inflammation by hypoxia in immunological niches
2017
Angiogenesis in cancer and other diseases
2000 StandoutNature
The Hallmarks of Cancer
2000 Standout
HIF-1 and mechanisms of hypoxia sensing
2001 StandoutNobel
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Cobalt and desferrioxamine reveal crucial members of the oxygen sensing pathway in HepG2 cells
1997
Hypoxia and the regulation of gene expression
1998 StandoutNobel
Oxygen-sensing under the influence of nitric oxide
2009
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Mammalian oxygen sensing and hypoxia inducible factor-1
1997 StandoutNobel
Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions
1997 Standout
Cellular Oxygen Sensors
1994
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Hypoxic induction of hypoxia-inducible factor-1α and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells
2002
Nitric oxide affects the production of reactive oxygen species in hepatoma cells: implications for the process of oxygen sensing
2000
Oxygen regulated gene expression: Erythropoietin as a model system
1997 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Hypoxia inducible factor (HIF) function in innate immunity and infection
2007
Perspectives on Oxygen Sensing
1999 StandoutNobel
Regulation of the Erythropoietin Gene
1989
Activation of Hypoxia-inducible Transcription Factor Depends Primarily upon Redox-sensitive Stabilization of Its α Subunit
1996
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Diphenylene Iodonium Inhibits the Induction of Erythropoietin and Other Mammalian Genes by Hypoxia
1995
Identification of Hypoxically Inducible mRNAs in HeLa Cells Using Differential‐Display PCR
1996 StandoutNobel
Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes
1999
Mammalian Oxygen Sensing, Signalling and Gene Regulation
2000
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Redistribution of Intracellular Oxygen in Hypoxia by Nitric Oxide: Effect on HIF1α
2003 Science
Toll-like Receptor 4 Modulation as a Strategy to Treat Sepsis
2010
Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α
1998 StandoutNobel
Hypoxic induction of gene expression in chronic granulomatous disease- derived B-cell lines: oxygen sensing is independent of the cytochrome b558-containing nicotinamide adenine dinucleotide phosphate oxidase
1996
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
2001 StandoutNobel
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
Oxygen Sensing and HIF-1 Activation Does Not Require an Active Mitochondrial Respiratory Chain Electron-transfer Pathway
2001
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress
2001
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Nitric Oxide Impairs Normoxic Degradation of HIF-1α by Inhibition of Prolyl Hydroxylases
2003
Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling
2002 StandoutScienceNobel
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
2002 StandoutNobel
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Regulation of the Erythropoietin Gene
1999
Involvement of a local Fenton reaction in the reciprocal modulation by O2 of the glucagon-dependent activation of the phosphoenolpyruvate carboxykinase gene and the insulin-dependent activation of the glucokinase gene in rat hepatocytes
1998
Regulation of Mammalian O2Homeostasis by Hypoxia-Inducible Factor 1
1999 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Cytochromes and oxygen radicals as putative members of the oxygen sensing pathway
1998
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Hypoxia-inducible factor 1: master regulator of O2 homeostasis
1998 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
1998 Standout
Induction of Endothelial PAS Domain Protein-1 by Hypoxia: Characterization and Comparison With Hypoxia-Inducible Factor-1α
1998 StandoutNobel
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Oxygen Sensing, Hypoxia-Inducible Factor-1 and the Regulation of Mammalian Gene Expression
1998 StandoutNobel
Short Hairpin RNA Interference Therapy for Ischemic Heart Disease
2008
Works of Stilla Frede being referenced
Regulation of Hypoxia‐Inducible Factors During Inflammation
2007
Cobalt chloride and desferrioxamine antagonize the inhibition of erythropoietin production by reactive oxygen species
1997
Inhibition of Erythropoietin Production by Cytokines
1994
Hypoxia-inducible erythropoietin gene expression in human neuroblastoma cells
2002
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB
2006
Antagonism of Lipopolysaccharide-Induced Blood Pressure Attenuation and Vascular Contractility
2007
Role of hydrogen peroxide in hypoxia-induced erythropoietin production
1994