Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes
2012 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Protein stability promotes evolvability
2006 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
SCHEMA Recombination of a Fungal Cellulase Uncovers a Single Mutation That Contributes Markedly to Stability
2009 StandoutNobel
Structure-Guided Recombination Creates an Artificial Family of Cytochromes P450
2006 StandoutNobel
Helicobacter pylori Vacuolating Cytotoxin, VacA, Is Responsible for Gastric Ulceration
2004
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Global incorporation of norleucine in place of methionine in cytochrome P450 BM‐3 heme domain increases peroxygenase activity
2003 StandoutNobel
Effect of Anthrax Toxin's Lethal Factor on Ion Channels Formed by the Protective Antigen
1995
Diversity of the Vaginal Microbiome Correlates With Preterm Birth
2013
Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori
2003
Dynamics and associations of microbial community types across the human body
2014 StandoutNature
Helicobacter pylori Vacuolating Cytotoxin Induces Activation of the Proapoptotic Proteins Bax and Bak, Leading to Cytochrome c Release and Cell Death, Independent of Vacuolation
2006
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
2000
Post‐Crystal Engineering of Zinc‐Substituted Myoglobin to Construct a Long‐Lived Photoinduced Charge‐Separation System
2011 StandoutNobel
Phagosome maturation: going through the acid test
2008
Helicobacter pylori in Health and Disease
2009
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Multiple Oligomeric States of the Helicobacter pylori Vacuolating Toxin Demonstrated by Cryo-electron Microscopy
2002 StandoutNobel
The Acid Activation ofHelicobacter pyloriToxin VacA: Structural and Membrane Binding Studies
1998
Functional Evolution and Structural Conservation in Chimeric Cytochromes P450
2004 StandoutNobel
Autophagy, Immunity, and Microbial Adaptations
2009
Defining the core Arabidopsis thaliana root microbiome
2012 StandoutNature
Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam
2001
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Heme-thiolate haloperoxidases: versatile biocatalysts with biotechnological and environmental significance
2006
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Methods in Mammalian Autophagy Research
2010 Standout
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
The Role of Sequestration in G Protein-coupled Receptor Resensitization
1997 StandoutNobel
Helicobacter pyloriInfection
2002 Standout
Autophagy and innate immunity: Triggering, targeting and tuning
2010
The Inflammasomes
2010 Standout
The Hallmarks of Aging
2013 Standout
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
1999
Enantioselective oxidations of sulfides catalyzed by chloroperoxidase
1990
An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA
2005 StandoutNatureNobel
The Regulation of Apoptosis by Microbial Pathogens
1999
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Functional Properties of the p33 and p55 Domains of the Helicobacter pylori Vacuolating Cytotoxin
2005
The Sialic Acid Binding SabA Adhesin of Helicobacter pylori Is Essential for Nonopsonic Activation of Human Neutrophils
2005
Autophagy in immunity and inflammation
2011 StandoutNature
Atg9 Vesicles Recruit Vesicle-tethering Proteins Trs85 and Ypt1 to the Autophagosome Formation Site
2012 StandoutNobel
Selective translocation of the A chain of diphtheria toxin across the membrane of purified endosomes.
1992
Role of Rab GTPases in Membrane Traffic and Cell Physiology
2011
Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2
1999 StandoutScience
Solute Solvent Dynamics and Energetics in Enzyme Catalysis: The SN2 Reaction of Dehalogenase as a General Benchmark
2004 StandoutNobel
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells
2000
Investigations of Heme Ligation and Ligand Switching in Cytochromes P450 and P420
2013
Kinetic Isotope Effect Analysis of the Ribosomal Peptidyl Transferase Reaction
2005
Advances in targeted therapeutic agents
2010
The Human Microbiome Project strategy for comprehensive sampling of the human microbiome and why it matters
2012
All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion
2005
A model of anthrax toxin lethal factor bound to protective antigen
2005 StandoutNobel
The Helicobacter pylori vacuoloating cytotoxin: from cellular vacuolation to immunosuppressive activities
2004
Evidence that translocation of anthrax toxin's lethal factor is initiated by entry of its N terminus into the protective antigen channel
2004
Enantioselective Imidation of Sulfides via Enzyme-Catalyzed Intermolecular Nitrogen-Atom Transfer
2014 StandoutNobel
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
How Much Do Enzymes Really Gain by Restraining Their Reacting Fragments?
2002 StandoutNobel
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
Metagenomics of the Human Body
2010
Membrane channel structure of Helicobacter pylori vacuolating toxin: Role of multiple GXXXG motifs in cylindrical channels
2004
A View at the Millennium: the Efficiency of Enzymatic Catalysis
2002
Extracellular Bad fused to toxin transport domains induces apoptosis.
2002
From Structure to Function: the Ecology of Host-Associated Microbial Communities
2010
A family of thermostable fungal cellulases created by structure-guided recombination
2009 StandoutNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
On the conservative nature of intragenic recombination
2005 StandoutNobel
Bioinspired Metal–Organic Framework Catalysts for Selective Methane Oxidation to Methanol
2018 StandoutNobel
Preterm labor: One syndrome, many causes
2014 StandoutScience
Methane-Oxidizing Enzymes: An Upstream Problem in Biological Gas-to-Liquids Conversion
2016
Involvement of a Cytochrome P450 Monooxygenase in Thaxtomin A Biosynthesis by Streptomyces acidiscabies
2002
Structural basis for cell surface patterning through NetrinG-NGL interactions
2011
ENZYMATIC TRANSITION STATES AND TRANSITION STATE ANALOG DESIGN
1998
Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.
2003
Inhibition of primary human T cell proliferation byHelicobacter pylorivacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
2004
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Anthrax Toxin
2003
Substrate für schnelle Ladungsübertragung auf redoxaktive Cofaktoren in den aktiven Zentren von Proteinen
1999
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Unravelling the effects of the environment and host genotype on the gut microbiome
2011
Structural Adaptability Facilitates Histidine Heme Ligation in a Cytochrome P450
2015 StandoutNobel
Works of Steven R. Blanke being referenced
Helicobacter pylorivacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity
2004
Cellular Vacuolation and Mitochondrial Cytochrome c Release Are Independent Outcomes of Helicobacter pylori Vacuolating Cytotoxin Activity That Are Each Dependent on Membrane Channel Formation
2003
Probing the Heme Iron Coordination Structure of Alkaline Chloroperoxidase
1996
Helicobacter pylori VacA, a paradigm for toxin multifunctionality
2005
Probing the Heme Iron Coordination Structure of Pressure-Induced Cytochrome P420cam
1996
Functional complementation reveals the importance of intermolecular monomer interactions for Helicobacter pylori VacA vacuolating activity
2002
Active-Site Mutations of the Diphtheria Toxin Catalytic Domain: Role of Histidine-21 in Nicotinamide Adenine Dinucleotide Binding and ADP-Ribosylation of Elongation Factor 2
1994
Identification of the Minimal Intracellular Vacuolating Domain of the Helicobacter pylori Vacuolating Toxin
1999
Effect ofHelicobacter pylori’s vacuolating cytotoxin on the autophagy pathway in gastric epithelial cells
2009
Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin
1996
A Dominant Negative Mutant of Helicobacter pyloriVacuolating Toxin (VacA) Inhibits VacA-induced Cell Vacuolation
1999
Response: strain‐specific activation of NF‐κB by Helicobacter pylori CagA
2009
Does Diphtheria Toxin Have Nuclease Activity?
1990 Science
Heterogeneity of Vaginal Microbial Communities within Individuals
2009
Sphingomyelin is important for the cellular entry and intracellular localization of Helicobacter pylori VacA
2010
Mutational Analysis of the Helicobacter pylori Vacuolating Toxin Amino Terminus: Identification of Amino Acids Essential for Cellular Vacuolation
2000
Identification of the fifth axial heme ligand of chloroperoxidase.
1988
Transition State Structure for the Hydrolysis of NAD+Catalyzed by Diphtheria Toxin
1997
Helicobacter pylori VacA Toxin Promotes Bacterial Intracellular Survival in Gastric Epithelial Cells
2006
Fluorescence Resonance Energy Transfer Microscopy of the Helicobacter pylori Vacuolating Cytotoxin within Mammalian Cells
2002
Activation of the abundant nuclear factor poly(ADP-ribose) polymerase-1 by Helicobacter pylori
2009
Fused polycationic peptide mediates delivery of diphtheria toxin A chain to the cytosol in the presence of anthrax protective antigen.
1996
Development of semi-continuous and continuous flow bioreactors for the high level production of chloroperoxidase
1989
Plasma Membrane Cholesterol Modulates Cellular Vacuolation Induced by the Helicobacter pylori Vacuolating Cytotoxin
2002