Citation Impact
Citing Papers
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease
2019
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol
2011 Standout
Species differences and molecular determinant of TRPA1 cold sensitivity
2013
A Gain-of-Function Mutation in TRPA1 Causes Familial Episodic Pain Syndrome
2010
Gctf: Real-time CTF determination and correction
2015 Standout
Single particle electron cryo-microscopy of a mammalian ion channel
2014 StandoutNobel
Molecular Basis Determining Inhibition/Activation of Nociceptive Receptor TRPA1 Protein
2014
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Evolution of cell-based reagent provision
2007
2-Amino-4-arylthiazole compounds as TRPA1 antagonists (WO 2012085662): a patent evaluation
2012
Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction
2020 Standout
Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research
2007 Standout
Zinc activates damage-sensing TRPA1 ion channels
2009 StandoutNobel
Natural products: An evolving role in future drug discovery
2011 Standout
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
Activation of TRPA1 channels by fenamate nonsteroidal anti-inflammatory drugs
2009
A nonpungent component of steamed ginger—[10]-shogaol—increases adrenaline secretion via the activation of TRPV1
2006
Structure–functional intimacies of transient receptor potential channels
2009
Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system
2009
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Gene Augmentation Therapy Restores Retinal Function and Visual Behavior in a Sheep Model of CNGA3 Achromatopsia
2015
Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects
2011 Standout
Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets
2007
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
2008 StandoutNobel
Temperature-dependent STIM1 activation induces Ca2+ influx and modulates gene expression
2011 StandoutNobel
R(+)-Methanandamide and Other Cannabinoids Induce the Expression of Cyclooxygenase-2 and Matrix Metalloproteinases in Human Nonpigmented Ciliary Epithelial Cells
2006
TRPV1 Is Activated by Both Acidic and Basic pH
2009 StandoutNobel
TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists
2006
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Implementation of a Fluorescence-Based Screening Assay Identifies Histamine H3 Receptor Antagonists Clobenpropit and Iodophenpropit as Subunit-Selective N-Methyl-d-Aspartate Receptor Antagonists
2010
A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid
2005
Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor
2005
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPA1 Contributes to Cold Hypersensitivity
2010 StandoutNobel
Reducing cannabinoid abuse and preventing relapse by enhancing endogenous brain levels of kynurenic acid
2013
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
How were new medicines discovered?
2011 Standout
Structure of the TRPV1 ion channel determined by electron cryo-microscopy
2013 StandoutNatureNobel
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
2021 StandoutNobel
Oxidative Stress in Cancer
2020 Standout
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
2012 StandoutNobel
The structural basis of function in Cys-loop receptors
2010
Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
2008 Standout
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
2008 StandoutNobel
Unusual Pungency from Extra-Virgin Olive Oil Is Attributable to Restricted Spatial Expression of the Receptor of Oleocanthal
2011
Development of the First Ultra-Potent “Capsaicinoid” Agonist at Transient Receptor Potential Vanilloid Type 1 (TRPV1) Channels and Its Therapeutic Potential
2005
Membrane mimetic systems in CryoEM: keeping membrane proteins in their native environment
2019 StandoutNobel
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
Transient Receptor Potential Cation Channels in Disease
2007 Standout
TRPA1 as a drug target—promise and challenges
2015
The Super-Cooling Agent Icilin Reveals a Mechanism of Coincidence Detection by a Temperature-Sensitive TRP Channel
2004 StandoutNobel
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
2009 StandoutNobel
The Met268Pro Mutation of Mouse TRPA1 Changes the Effect of Caffeine from Activation to Suppression
2010
Pungent Qualities of Sanshool-Related Compounds Evaluated by a Sensory Test and Activation of Rat TRPV1
2005
Impact of high-throughput screening in biomedical research
2011 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition
2012
Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels
2009
The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic Applications
2005
Chemosensory Properties of the Trigeminal System
2010
Triazole Ligands Reveal Distinct Molecular Features That Induce Histamine H4 Receptor Affinity and Subtly Govern H4/H3 Subtype Selectivity
2011
Discovery, Optimization, and Biological Evaluation of 5-(2-(Trifluoromethyl)phenyl)indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists
2014 StandoutNobel
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
TRP Channels and Pain
2013 StandoutNobel
Neuropathic Pain: From Mechanisms to Treatment
2020 Standout
Resiniferatoxin Binds to the Capsaicin Receptor (TRPV1) near the Extracellular Side of the S4 Transmembrane Domain
2004
Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control
2008
Allosteric Receptors: From Electric Organ to Cognition
2010
Beta-caryophyllene is a dietary cannabinoid
2008
Identification and Biological Evaluation of 4-(3-Trifluoromethylpyridin-2-yl)piperazine-1-carboxylic Acid (5-Trifluoromethylpyridin-2-yl)amide, a High Affinity TRPV1 (VR1) Vanilloid Receptor Antagonist
2004
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels
2008
Emerging Targets in Photopharmacology
2016 StandoutNobel
Chemical activation of the mechanotransduction channel Piezo1
2015 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as Emerging Target for Novel Analgesics and Anti-Inflammatory Agents
2010
Polymodal Ligand Sensitivity of TRPA1 and Its Modes of Interactions
2009
The μ Opioid Agonist Morphine Modulates Potentiation of Capsaicin-Evoked TRPV1 Responses through a Cyclic AMP-Dependent Protein Kinase a Pathway
2006
Works of Steven Cassar being referenced
Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
2008
Use of a Fluorescent Imaging Plate Reader-Based Calcium Assay to Assess Pharmacological Differences between the Human and Rat Vanilloid Receptor
2002
Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment
2008
Utility of Large-Scale Transiently Transfected Cells for Cell-Based High-Throughput Screens to Identify Transient Receptor Potential Channel A1 (TRPA1) Antagonists
2006
Detection of multiple H3receptor affinity states utilizing [3H]A‐349821, a novel, selective, non‐imidazole histamine H3receptor inverse agonist radioligand
2006
Association of Catsper1 or -2 with Cav3.3 Leads to Suppression of T-type Calcium Channel Activity
2006
Molecular modeling and pharmacological analysis of species-related histamine H3 receptor heterogeneity
2003
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors
2004
Tissue specific expression of alternative splice forms of human cyclic nucleotide gated channel subunit CNGA3.
2004