Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
2009 Standout
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Parkin-catalyzed Ubiquitin-Ester Transfer Is Triggered by PINK1-dependent Phosphorylation
2013
Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation
2015 StandoutNobel
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
2009
The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress
2009 Standout
Dopamine-derived Dopaminochrome Promotes H2O2 Release at Mitochondrial Complex I
2005
Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5
2019
A Neo-Substrate that Amplifies Catalytic Activity of Parkinson’s-Disease-Related Kinase PINK1
2013
Cancer Cell Metabolism
2011
The Role of Autophagy in Parkinson's Disease
2012
Disease-Associated Mutations That Alter the RNA Structural Ensemble
2010
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Interaction of the c-Jun/JNK Pathway and Cyclin-dependent Kinases in Death of Embryonic Cortical Neurons Evoked by DNA Damage
2002
Calpain I Induces Cleavage and Release of Apoptosis-inducing Factor from Isolated Mitochondria
2004
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Mechanism and medical implications of mammalian autophagy
2018 Standout
Autophagy and the Integrated Stress Response
2010 Standout
The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases
2016
The role of autophagy in neurodegenerative disease
2013 Standout
Expression of the Ciona intestinalis Alternative Oxidase (AOX) in Drosophila Complements Defects in Mitochondrial Oxidative Phosphorylation
2009
Pharmacological manipulation of cell death: clinical applications in sight?
2005
PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin
2010 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders
2008
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling
2009
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
2012
TRAP1 rescues PINK1 loss-of-function phenotypes
2013
p53 in neuronal apoptosis
2005
Genetic Animal Models of Parkinson's Disease
2010
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
2016 Standout
Hexokinase activity is required for recruitment of parkin to depolarized mitochondria
2013
The molecular biology of head and neck cancer
2010 Standout
Expression analysis of dopaminergic neurons in Parkinson’s disease and aging links transcriptional dysregulation of energy metabolism to cell death
2011
Autophagy: Renovation of Cells and Tissues
2011 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Regulation of p53 tumour suppressor target gene expression by the p52 NF‐κB subunit
2006
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Clinical potential of minocycline for neurodegenerative disorders
2004
PINK1 cleavage at position A103 by the mitochondrial protease PARL
2010
Mitochondrial Alterations in PINK1 Deficient Cells Are Influenced by Calcineurin-Dependent Dephosphorylation of Dynamin-Related Protein 1
2009
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Mitochondrial fragmentation in neurodegeneration
2008
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
2005 StandoutNobel
Regulation of cancer cell metabolism
2011 Standout
Parkinson's disease
2015 Standout
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Autophagy in Human Health and Disease
2013 Standout
Whole Chromosome Instability Caused by Bub1 Insufficiency Drives Tumorigenesis through Tumor Suppressor Gene Loss of Heterozygosity
2009
Mechanisms of mitophagy
2010 Standout
ALSoD: A user-friendly online bioinformatics tool for amyotrophic lateral sclerosis genetics
2012
Insights into RNA structure and function from genome-wide studies
2014 StandoutNobel
Down-regulation of apoptosis mediators by RNAi inhibits axotomy-induced retinal ganglion cell death in vivo
2005
Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease
2008
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
PINK1 Triggers Autocatalytic Activation of Parkin to Specify Cell Fate Decisions
2014
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
The relevance of iron in the pathogenesis of Parkinson’s disease
2010
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy
2010
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
2013 Nature
Calcium(II) selectively induces α‐synuclein annular oligomers via interaction with the C‐terminal domain
2004
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Alpha-synuclein-induced neurodegeneration is exacerbated in PINK1 knockout mice
2014
Perturbations in Mitochondrial Dynamics Induced by Human Mutant PINK1 Can Be Rescued by the Mitochondrial Division Inhibitor mdivi-1
2010
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Mammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms
2009
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Characterization of PINK1 processing, stability, and subcellular localization
2008
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Involvement of Interferon-γ in Microglial-Mediated Loss of Dopaminergic Neurons
2007
Parkinson's Disease
2003 Standout
Cell death pathways in Parkinson’s disease: proximal triggers, distal effectors, and final steps
2009
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Thioredoxins, Glutaredoxins, and Peroxiredoxins—Molecular Mechanisms and Health Significance: from Cofactors to Antioxidants to Redox Signaling
2013
Protein Promiscuity in H 2 O 2 Signaling
2018
Brain Repair
2007
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson’s disease factors Pink1 and Parkin
2008
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Multiple Functions and Regulation of Mammalian Peroxiredoxins
2017
Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease
2015
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
BimEL up‐regulation potentiates AIF translocation and cell death in response to MPTP
2005
The kinase domain of mitochondrial PINK1 faces the cytoplasm
2008
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
2013
Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress
2003
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Pink1 Forms a Multiprotein Complex with Miro and Milton, Linking Pink1 Function to Mitochondrial Trafficking
2009
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
2010
Genes associated with Parkinson's disease: regulation of autophagy and beyond
2015
Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy
2009 Science
Lithium Blocks the c-Jun Stress Response and Protects Neurons via Its Action on Glycogen Synthase Kinase 3
2003
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
2005
The Role of Atg Proteins in Autophagosome Formation
2011 StandoutNobel
Works of Steve Callaghan being referenced
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway
2010
Required Roles of Bax and JNKs in Central and Peripheral Nervous System Death of Retinoblastoma-deficient Mice
2007
Nuclear Factor-κB Modulates the p53 Response in Neurons Exposed to DNA Damage
2004
Inactivation of Pink1 Gene in Vivo Sensitizes Dopamine-producing Neurons to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Can Be Rescued by Autosomal Recessive Parkinson Disease Genes, Parkin or DJ-1
2012
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons
2012
General mutation databases: analysis and review
2007
Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models,In Vivo
2009
Role of Cdk5-Mediated Phosphorylation of Prx2 in MPTP Toxicity and Parkinson's Disease
2007
Calpain-Regulated p35/cdk5 Plays a Central Role in Dopaminergic Neuron Death through Modulation of the Transcription Factor Myocyte Enhancer Factor 2
2006
c-Jun mediates axotomy-induced dopamine neuron death in vivo
2001
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
2008
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage
2007
Inhibition of Calpains Prevents Neuronal and Behavioral Deficits in an MPTP Mouse Model of Parkinson's Disease
2003