Citation Impact
Citing Papers
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
TGF-β and cancer
1999
Inflammation and cancer
2002 StandoutNature
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Tumors are unique organs defined by abnormal signaling and context
2001
Role of Transforming Growth Factor β in Human Disease
2000 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Identification of a Stat Gene That Functions in Drosophila Development
1996
Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity
1999
Cell-cycle checkpoints and cancer
2004 StandoutNature
Chk1 and Chk2 kinases in checkpoint control and cancer
2003
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
SMAD genes in juvenile polyposis
1999
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility
2003
Genetic pathways in colorectal and other cancers
1999
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
2003
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
2014 StandoutNature
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
PTEN: One Gene, Many Syndromes
2003
A combined syndrome of juvenile polyposis and hereditary haemorrhagic telangiectasia associated with mutations in MADH4 ( SMAD4)
2004 Standout
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice
2000
The Chk2 protein kinase
2004
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
2010
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
2005
Putting tumours in context
2001 Standout
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
2001
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Mouse models for colorectal cancer
1999
Searching for the hereditary causes of renal-cell carcinoma
2004
The Fanconi Anemia/BRCA pathway: new faces in the crowd
2005
Identification and expansion of human colon-cancer-initiating cells
2006 StandoutNature
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Constipation, polyps, or cancer? let PTEN predict your future
2003
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Hereditary Colorectal Cancer
2003 Standout
Genetic predisposition to colorectal cancer
2004
Mutations of the human PTEN gene
2000
Signaling of transforming growth factor‐β family members through Smad proteins
2000
Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis
1999
Epithelial-Mesenchymal Transition
2009
Coeliac disease: dissecting a complex inflammatory disorder
2002
The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis
1999
The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase
2003
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Cancer-related inflammation
2008 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Co-evolution of tumor cells and their microenvironment
2008
TGF-β signaling by Smad proteins
2000
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Mechanism of 5′-Directed Excision in Human Mismatch Repair
2003 StandoutNobel
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
2007 StandoutNature
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt–β-catenin signaling
2004
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
The cancer genome
2009 StandoutNature
TGF-β signaling by Smad proteins
2000
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Computational Design of an α-Gliadin Peptidase
2012 StandoutNobel
Mutations in the tumor suppressors Smad2 and Smad4 inactivate transforming growth factor β signaling by targeting Smads to the ubiquitin–proteasome pathway
2000
Smad4/DPC4-mediated tumor suppression through suppression of angiogenesis
2000
De Novo Crypt Formation and Juvenile Polyposis on BMP Inhibition in Mouse Intestine
2004 Science
STATs and Gene Regulation
1997 StandoutScience
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice.
2002
Self-Renewal and Cancer of the Gut: Two Sides of a Coin
2005 Science
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Pten is essential for embryonic development and tumour suppression
1998 Standout
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
2015
Smad4/DPC4 Silencing and Hyperactive Ras Jointly Disrupt Transforming Growth Factor-β Antiproliferative Responses in Colon Cancer Cells
1999
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice.
1999
The Putative Tumor Suppressor Cdx2 Is Overexpressed by Human Colorectal Adenocarcinomas
2005
Surfing the p53 network
2000 StandoutNature
Targeted Disruption of Smad3 Reveals an Essential Role in Transforming Growth Factor β-Mediated Signal Transduction
1999
Myofibroblasts. II. Intestinal subepithelial myofibroblasts
1999
Convergence of Transforming Growth Factor-β and Vitamin D Signaling Pathways on SMAD Transcriptional Coactivators
1999 Science
The spatial relationship between stem cells and their progeny in the basal layer of human epidermis: a new view based on whole-mount labelling and lineage analysis
1999
DNA Repair Pathways in Clinical Practice: Lessons From Pediatric Cancer Susceptibility Syndromes
2006
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
TbetaR-I(6A) is a candidate tumor susceptibility allele.
1999
STEM CELL NICHE: Structure and Function
2005
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
TGF-β and cancer
2005
Dysregulation of the TSC-mTOR pathway in human disease
2004 Standout
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
SIGNALING PATHWAYS IN INTESTINAL DEVELOPMENT AND CANCER
2004
Genetic Testing for Cancer Predisposition
2001
Engineering of Kuma030: A Gliadin Peptidase That Rapidly Degrades Immunogenic Gliadin Peptides in Gastric Conditions
2015 StandoutNobel
Works of Steve Bevan being referenced
Screening SMAD1 , SMAD2 , SMAD3 , and SMAD5 for germline mutations in juvenile polyposis syndrome
1999
Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas
2002
CHEK2 variants in susceptibility to breast cancer and evidence of retention of the wild type allele in tumours
2002
Retroviral Marking Identifies Grafted Autologous Keratinocytes in Porcine Wounds Receiving Cultured Epithelium
1997
Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke
2009
Analysis of the Fanconi Anaemia Complentation Group A Gene in Acute Myeloid Leukaemia
2002
Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer
2003
Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases
1998
Low frequency of somatic mutations in the FH/multiple cutaneous leiomyomatosis gene in sporadic leiomyosarcomas and uterine leiomyomas
2002
CDX2 mutations do not account for juvenile polyposis or Peutz–Jeghers syndrome and occur infrequently in sporadic colorectal cancers
2001
Analysis of the CTLA4 Gene in Swedish Coeliac Disease Patients
2002
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer.
2003
Allelic loss at SMAD4 in polyps from juvenile polyposis patients and use of fluorescence in situ hybridization to demonstrate clonal origin of the epithelium.
2000
Mutations in the SMAD4/DPC4 Gene in Juvenile Polyposis
1998 Science
IFN-γ induces a p91/Stat1α-related transcription factor with distinct activation and binding properties
1996