Citation Impact
Citing Papers
Sestrin2 is a leucine sensor for the mTORC1 pathway
2015 Science
Obesity and Metabolic Syndrome in Circadian Clock Mutant Mice
2005 StandoutScience
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Frailty in Older Adults: Evidence for a Phenotype
2001 Standout
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
PAGE: Parametric Analysis of Gene Set Enrichment
2005
Strength and Aerobic Training Attenuate Muscle Wasting and Improve Resistance to the Development of Disability With Aging
1995
A core gut microbiome in obese and lean twins
2008 StandoutNature
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1−/− mice
2003
Age and sex affect human muscle fibre adaptations to heavy‐resistance strength training
2006
HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence
2005
The myotonic dystrophy expanded CUG repeat tract is necessary but not sufficient to disrupt C2C12 myoblast differentiation
2001
Abdominal obesity and metabolic syndrome
2006 StandoutNature
mTOR Signaling in Growth Control and Disease
2012 Standout
Proteins binding to duplexed RNA: one motif, multiple functions
2000
Identification of genes in toxicity pathways of trinucleotide-repeat RNA in C. elegans
2014 StandoutNobel
Inflammation and metabolic disorders
2006 StandoutNature
The Response to Long-Term Overfeeding in Identical Twins
1990
Body Composition in Elderly Men: Effect of Dietary Modification during Strength Training
1992
Regulation of Energy Expenditure in Aging Humans
1993
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
1995 Standout
Nutritional Regulation of the Insulin-Like Growth Factors*
1994
RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
2013
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
1995
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
1997 StandoutNature
Central nervous system control of food intake and body weight
2006 StandoutNature
Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks
1995 StandoutScience
Covert manipulation of dietary fat and energy density: effect on substrate flux and food intake in men eating ad libitum
1995
Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons
2004
Changes in myosin heavy chain mRNA and protein expression in human skeletal muscle with age and endurance exercise training
2005
Effects of Strength Training and Detraining on Muscle Quality: Age and Gender Comparisons
2000
Ghrelin: An orexigenic and somatotrophic signal from the stomach
2001
Physiological Regulation of Body Weight and the Issue of Obesity
1989
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs
2007
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
2010 StandoutNobel
Serum Immunoreactive-Leptin Concentrations in Normal-Weight and Obese Humans
1996 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
The single-cell transcriptional landscape of mammalian organogenesis
2019 StandoutNature
Effects of Age, Gender, and Myostatin Genotype on the Hypertrophic Response to Heavy Resistance Strength Training
2000
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Mice with Mitochondrial Complex I Deficiency Develop a Fatal Encephalomyopathy
2008
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
2008 Standout
The effect of recombinant human growth hormone and resistance training on IGF‐I mRNA expression in the muscles of elderly men
2003
The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes
2009
RNA CUG Repeats Sequester CUGBP1 and Alter Protein Levels and Activity of CUGBP1
2001
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
Aging and Gene Expression in the Primate Brain
2005 StandoutNobel
Aging of the human neuromuscular system
2001
Exercise and aging
2004
Stem cells, ageing and the quest for immortality
2006 StandoutNature
Effects of Resistance Training on Older Adults
2004
Prescribing Aerobic Exercise for the Regulation of Postprandial Lipid Metabolism
2006
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis
2011
In vivo human muscle structure and function: adaptations to resistance training in old age
2004
The dsRNA Binding Protein RDE-4 Interacts with RDE-1, DCR-1, and a DExH-Box Helicase to Direct RNAi in C. elegans
2002 StandoutNobel
Obesity as a medical problem
2000 StandoutNature
Changes in Power with Resistance Training in Older and Younger Men and Women
1999
Muscle-derived stem/progenitor cell dysfunction limits healthspan and lifespan in a murine progeria model
2012
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1998 StandoutNature
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
2005 StandoutNature
Role of the Insulin-Like Growth Factor Family in Cancer Development and Progression
2000
Overfeeding and energy expenditure in humans
1992
The Hallmarks of Aging
2013 Standout
Discrepancy between Self-Reported and Actual Caloric Intake and Exercise in Obese Subjects
1992
Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
2010
Age and gender responses to strength training and detraining
2000
Reduced Rate of Energy Expenditure as a Risk Factor for Body-Weight Gain
1988
Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
2015 Standout
Gene expression profiling of human satellite cells during muscular aging using cDNA arrays
2003
Muscle Size Responses to Strength Training in Young and Older Men and Women
2001
Changes in Energy Expenditure Resulting from Altered Body Weight
1995 Standout
RNA‐mediated neurodegeneration in repeat expansion disorders
2009
A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator
1997
Increased energy requirements and changes in body composition with resistance training in older adults
1994
The role of nuclear architecture in genomic instability and ageing
2007
Resistance training and intra-abdominal adipose tissue in older men and women
2002
The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
2001
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene
1995 StandoutScience
Signals mediating skeletal muscle remodeling by resistance exercise: PI3-kinase independent activation of mTORC1
2010
Exercise and Physical Activity for Older Adults
2009 Standout
Myotonic Dystrophy in Transgenic Mice Expressing an Expanded CUG Repeat
2000 Science
Effects of Size and Temperature on Metabolic Rate
2001 StandoutScience
Skeletal muscle mass and distribution in 468 men and women aged 18–88 yr
2000 Standout
Mechanisms Underlying the Cost of Living in Animals
2000
Mitochondrial DNA Mutations, Oxidative Stress, and Apoptosis in Mammalian Aging
2005 StandoutScience
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
2011 StandoutNobel
Effect of resistance training on skeletal muscle-specific force in elderly humans
2004
Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis
2007 StandoutScience
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences
2015
Environmental Contributions to the Obesity Epidemic
1998 StandoutScience
Muscle quality. II. Effects of strength training in 65- to 75-yr-old men and women
1999
Notch-Mediated Restoration of Regenerative Potential to Aged Muscle
2003 Science
Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle
1997
Meta-analysis of age-related gene expression profiles identifies common signatures of aging
2009
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
2013
Decline in skeletal muscle mitochondrial function with aging in humans
2005
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
2015 Science
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Metabolic Effects of Fructose and the Worldwide Increase in Obesity
2010
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
The Long-Term Stability of the Human Gut Microbiota
2013 StandoutScience
Large energetic adaptations of elderly muscle to resistance and endurance training
2001
Peptidomimetic Regulation of Growth Hormone Secretion
1997
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
1999 StandoutNature
Recruitment of human muscleblind proteins to (CUG)n expansions associated with myotonic dystrophy
2000
Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia
2001
Vitamin A (retinol) status of first nation adults with non-insulin-dependent diabetes mellitus.
1997
Obesity and the Environment: Where Do We Go from Here?
2003 StandoutScience
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
Familial Dependence of the Resting Metabolic Rate
1986
Works of Stephen Welle being referenced
Effect of age on muscle hypertrophy induced by resistance training
1996
Reduced metabolic rate during β-adrenergic blockade in humans
1991
Effect of Age on Muscle Hypertrophy Induced by Resistance Training
1996
Total and resting energy expenditure in obese women reduced to ideal body weight.
1993
Insulin-like growth factor-1 and myostatin mRNA expression in muscle: comparison between 62–77 and 21–31 yr old men
2002
Sex-Related Differences in Gene Expression in Human Skeletal Muscle
2008
Exogenous insulin replacement in type 2 diabetes reverses excessive hepatic glucose release, but not excessive renal glucose release and impaired free fatty acid clearance
2002
Abnormal renal, hepatic, and muscle glucose metabolism following glucose ingestion in type 2 diabetes
2004
Cellular and Molecular Basis of Age-Related Sarcopenia
2002
Expanded CUG repeat RNAs form hairpins that activate the double-stranded RNA-dependent protein kinase PKR
2000
Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1
2006
Deliberate overfeeding in women and men: energy cost and composition of the weight gain
1986
Uptake and release of glucose by the human kidney. Postabsorptive rates and responses to epinephrine.
1995
Energy expenditure under free-living conditions in normal-weight and overweight women
1992
Ragged Red Fibers in Normal Aging and Inflammatory Myopathy
1995
Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice
2009
Skeletal muscle gene expression profiles in 20–29 year old and 65–71 year old women
2003
Insulin-like growth factor-I, actin, and myosin heavy chain messenger RNAs in skeletal muscle after an injection of growth hormone in subjects over 60 years old
1997
Transcriptional and post-transcriptional impact of toxic RNA in myotonic dystrophy
2009
Hormonal response to overfeeding
1989
Relationship of resting metabolic rate to body composition and protein turnover
1990
Lean body mass in obesity.
1983
Growth hormone and insulin-like growth factor-I as anabolic agents
1998
Thermic effect of feeding in man: Increased plasma norepinephrine levels following glucose but not protein or fat consumption
1981
Metabolic responses to a meal during rest and low-intensity exercise
1984
High-abundance mRNAs in human muscle: comparison between young and old
2000
Reduced amount of mitochondrial DNA in aged human muscle
2003
Myofibrillar protein synthesis in young and old men
1993
Genetic Deletion of Myostatin From the Heart Prevents Skeletal Muscle Atrophy in Heart Failure
2010
Growth hormone increases muscle mass and strength but does not rejuvenate myofibrillar protein synthesis in healthy subjects over 60 years old
1996
Failure of glyburide and insulin treatment to decrease leucine flux in obese type II diabetic patients.
1990
Relation between extent of myostatin depletion and muscle growth in mature mice
2009
Growth hormone increases muscle mass and strength but does not rejuvenate myofibrillar protein synthesis in healthy subjects over 60 years old.
1996
Leucine as a regulator of whole body and skeletal muscle protein metabolism in humans
1992
Senescence-related changes in gene expression in muscle: similarities and differences between mice and men
2001
Polyadenylated RNA, actin mRNA, and myosin heavy chain mRNA in young and old human skeletal muscle
1996
Gene expression profile of aging in human muscle
2003
Stimulation of myofibrillar synthesis by exercise is mediated by more efficient translation of mRNA
1999
Myofibrillar protein synthesis in young and old human subjects after three months of resistance training
1995
Resting Metabolic Rates of Obese Women after Rapid Weight Loss*
1984