Citation Impact
Citing Papers
TRP Channels as Potential Drug Targets
2017
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Mammalian Transient Receptor Potential TRPA1 Channels: From Structure to Disease
2019
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
2009
UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling
2013
The role of bile acids in functional GI disorders
2014
Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces
2016
Arresting a Transient Receptor Potential (TRP) Channel
2010 StandoutNobel
Nociceptors: a phylogenetic view
2009
Intestinal Microbiota And Diet in IBS: Causes, Consequences, or Epiphenomena?
2015
The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli
2009
Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions
2010
The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+ Influx and ATP Release in Primary Urothelial Cell Cultures
2009
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Projections of 5-hydroxytryptamine-immunoreactive neurons in guinea-pig distal colon
1994
Functional Bowel Disorders
2006 Standout
An Update on Post-infectious Irritable Bowel Syndrome: Role of Genetics, Immune Activation, Serotonin and Altered Microbiome
2012
Effectiveness of probiotics in irritable bowel syndrome: Updated systematic review with meta-analysis
2015
Enteroendocrine cells and 5-HT availability are altered in mucosa of guinea pigs with TNBS ileitis
2004
Brain–Gut Microbiome Interactions and Functional Bowel Disorders
2014
Nucleotide signalling during inflammation
2014 StandoutNature
Enhanced excitability of myenteric AH neurones in the inflamed guinea‐pig distal colon
2003
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
2004
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
2014 StandoutNature
Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain
2014
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Acupuncture for Irritable Bowel Syndrome: Systematic Review and Meta-Analysis
2012
Cough and airway disease: The role of ion channels
2017
Irritant-evoked activation and calcium modulation of the TRPA1 receptor
2020 StandoutNatureNobel
The Human Intestinal Microbiome in Health and Disease
2016 Standout
Primary Afferent and Spinal Cord Expression of Gastrin-Releasing Peptide: Message, Protein, and Antibody Concerns
2015
The role of the gut microbiota in nutrition and health
2012 Standout
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Rectal bacteriotherapy for recurrent Clostridium difficile-associated diarrhoea: results from a case series of 55 patients in Denmark 2000–2012
2014
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
2007 Standout
Ligand‐gated ion channels in the enteric nervous system
2002
Linaclotide Inhibits Colonic Nociceptors and Relieves Abdominal Pain via Guanylate Cyclase-C and Extracellular Cyclic Guanosine 3′,5′-Monophosphate
2013
The Serotonin Signaling System: From Basic Understanding To Drug Development for Functional GI Disorders
2007 Standout
Towards a systems view of IBS
2015
The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4
2015
An SCN9A channelopathy causes congenital inability to experience pain
2006 StandoutNature
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Role of the Microbiota in Immunity and Inflammation
2014 Standout
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Mechanically Activated Ion Channels
2015 StandoutNobel
Beneficial modulation of the gut microbiota
2014
TRPA1 antagonists as potential analgesic drugs
2011
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
The Functional Gastrointestinal Disorders and the Rome III Process
2006 Standout
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
The development of allergic inflammation
2008 StandoutNature
The Devil Lies in the Details: How Variations in Polysaccharide Fine-Structure Impact the Physiology and Evolution of Gut Microbes
2014
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPV1
2014
17(R)‐resolvin D1 specifically inhibits transient receptor potential ion channel vanilloid 3 leading to peripheral antinociception
2011
TRPV1 structures in distinct conformations reveal activation mechanisms
2013 StandoutNatureNobel
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways
2008
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
Role of the gut microbiota in nutrition and health
2018 Standout
The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic
2014 Standout
Serotonin signalling in the gut—functions, dysfunctions and therapeutic targets
2013
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
Neuroplasticity and dysfunction after gastrointestinal inflammation
2014
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Mammalian somatosensory mechanotransduction
2009
5-hydroxytryptamine is a fast excitatory transmitter at 5-HT3 receptors in rat amygdala
1992
Adrenergic Stimulation Mediates Visceral Hypersensitivity to Colorectal Distension Following Heterotypic Chronic Stress
2009
Arterial Response to Shear Stress Critically Depends on Endothelial TRPV4 Expression
2007
PIEZO2 in sensory neurons and urothelial cells coordinates urination
2020 StandoutNatureNobel
Molecular Mechanisms of TRPV4‐Mediated Neural Signaling
2008
Incidence of Ischemic Colitis and Serious Complications of Constipation Among Patients Using Alosetron: Systematic Review of Clinical Trials and Post-Marketing Surveillance Data
2006
Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses
2009
Control of pathogens and pathobionts by the gut microbiota
2013
The role of Drosophila Piezo in mechanical nociception
2012 StandoutNatureNobel
Afferent Nerve Regulation of Bladder Function in Health and Disease
2009
Neuroimmune interactions in allergic skin diseases
2007
AGA technical review on irritable bowel syndrome
2002 Standout
Nociceptors—Noxious Stimulus Detectors
2007
Microbiota-mediated colonization resistance against intestinal pathogens
2013
Synaptic facilitation and enhanced neuronal excitability in the submucosal plexus during experimental colitis in guinea‐pig
2005
Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths
2012 Standout
Pharmacology of Vanilloid Transient Receptor Potential Cation Channels
2009
Crosstalk at the mucosal border: importance of the gut microenvironment in IBS
2014
Neuronal location of 5-hydroxytryptamine3 receptor-like immunoreactivity in the rat colon
2003
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
Multivariate modelling of faecal bacterial profiles of patients with IBS predicts responsiveness to a diet low in FODMAPs
2017
Irritable Bowel Syndrome
2015 Standout
The low FODMAP diet: recent advances in understanding its mechanisms and efficacy in IBS
2017
International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding
2010 Standout
Quality Indicators for Colonoscopy
2014
Microflora Modulation of Motility
2011
Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets
2014
Biased ligand quantification in drug discovery: from theory to high throughput screening to identify new biased μ opioid receptor agonists
2016
Signaling Pathways in Sensitization: Toward a Nociceptor Cell Biology
2007
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
2011
The evidence base for efficacy of the low FODMAP diet in irritable bowel syndrome: is it ready for prime time as a first‐line therapy?
2017
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Sodium Channels in Normal and Pathological Pain
2010
Nervous system distribution of the serotonin 5-HT3 receptor mRNA.
1993 StandoutNobel
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
The Brain-Gut Axis in Abdominal Pain Syndromes
2010
Quality Indicators for Colonoscopy
2006
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Quality indicators for colonoscopy
2014 Standout
The Role of Sodium Channels in Chronic Inflammatory and Neuropathic Pain
2006
TRPA1: A Gatekeeper for Inflammation
2012
Emerging Targets in Photopharmacology
2016 StandoutNobel
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV
2016 Standout
Works of Stephen Vanner being referenced
FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial
2016
Stool substitute transplant therapy for the eradication of Clostridium difficile infection: ‘RePOOPulating’ the gut
2013
Citrobacter rodentium colitis evokes post‐infectious hyperexcitability of mouse nociceptive colonic dorsal root ganglion neurons
2009
Ileitis modulates potassium and sodium currents in guinea pig dorsal root ganglia sensory neurons
2003
Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia
2008
The small intestinal bacterial overgrowth. Irritable bowel syndrome hypothesis: implications for treatment
2008
Activation of protease‐activated receptor‐4 inhibits the intrinsic excitability of colonic dorsal root ganglia neurons
2009
Basic and clinical pharmacology of new motility promoting agents
2005
Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice
2006
Cathepsin S Is Activated During Colitis and Causes Visceral Hyperalgesia by a PAR2-Dependent Mechanism in Mice
2011
Characterization of the Cysteinyl Leukotriene 2 Receptor in Novel Expression Sites of the Gastrointestinal Tract
2011
Inflammation‐induced hyperexcitability of nociceptive gastrointestinal DRG neurones: the role of voltage‐gated ion channels
2004
Protease‐activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ‐ and A‐dependent mechanisms in rats and mice
2006
Two TTX-resistant Na+ currents in mouse colonic dorsal root ganglia neurons and their role in colitis-induced hyperexcitability
2004
Submucosal secretomotor and vasodilator reflexes
2004
Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitis
2007
Brain–Gut Interactions Increase Peripheral Nociceptive Signaling in Mice With Postinfectious Irritable Bowel Syndrome
2011
Cathepsin S Causes Inflammatory Pain via Biased Agonism of PAR2 and TRPV4
2014
The TGR5 receptor mediates bile acid–induced itch and analgesia
2013
Mast cell tryptase and proteinase‐activated receptor 2 induce hyperexcitability of guinea‐pig submucosal neurons
2003
Effects of 5‐HT3receptor antagonists on 5‐HT and nicotinic depolarizations in guinea‐pig submucosal neurones
1990
Trinitrobenzenesulphonic acid colitis alters Nav 1.8 channel expression in mouse dorsal root ganglia neurons
2009
Detection of Bacterial Overgrowth in IBS Using the Lactulose H2 Breath Test: Comparison with 14C-d-Xylose and Healthy Controls
2005
Release of endogenous opioids during a chronic IBD model suppresses the excitability of colonic DRG neurons
2012
Split-dose administration of a dual-action, low-volume bowel cleanser for colonoscopy: the SEE CLEAR I study
2013
Sensitization of Peripheral Sensory Nerves by Mediators From Colonic Biopsies of Diarrhea-Predominant Irritable Bowel Syndrome Patients: A Role for PAR2
2013
The IBS-36: a new quality of life measure for irritable bowel syndrome
2002
Long Vasodilator Reflexes Projecting Through the Myenteric Plexus in Guinea‐Pig Ileum
2003
Intestinal microbiota in functional bowel disorders: a Rome foundation report
2012
Commonly Used Preparations for Colonoscopy: Efficacy, Tolerability and Safety – A Canadian Association of Gastroenterology Position Paper
2006
TNBS ileitis evokes hyperexcitability and changes in ionic membrane properties of nociceptive DRG neurons
2002
Cholinergic and noncholinergic submucosal neurons dilate arterioles in guinea pig colon
1991
Histamine-mediated potentiation of transient receptor potential (TRP) ankyrin 1 and TRP vanilloid 4 signaling in submucosal neurons in patients with irritable bowel syndrome
2019
Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice
2009
Myenteric neurons activate submucosal vasodilator neurons in guinea pig ileum
2000
Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons
2010
Using human intestinal biopsies to study the pathogenesis of irritable bowel syndrome
2014
Alterations in capsaicin-evoked electrolyte transport during the evolution of guinea pig TNBS ileitis
2002
A Canadian Working Group Report on Fecal Microbial Therapy: Microbial Ecosystems Therapeutics
2012
The intrinsic firing pattern of nociceptive sensory neurons innervating guinea pig ileum is enhanced by TNBS-Ileitis
2001
A placebo-controlled, double-blind trial of acupuncture in the treatment of irritable bowel syndrome (IBS)
2000
Mucosal stimulation evokes vasodilation in submucosal arterioles by neuronal and nonneuronal mechanisms
1993