Citation Impact
Citing Papers
A c-Myc–SIRT1 feedback loop regulates cell growth and transformation
2009
Evidence of a Role for Insulin-Like Growth Factor Binding Protein (IGFBP)-3 in Metabolic Regulation
2010
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
2013 Standout
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Leptin therapy in insulin-deficient type I diabetes
2010
Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
2009 StandoutScience
AMP-Activated Protein Kinase–Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol
2009
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
Sirtuins as regulators of metabolism and healthspan
2012 Standout
SIRT1 activator (SRT1720) improves the follicle reserve and prolongs the ovarian lifespan of diet-induced obesity in female mice via activating SIRT1 and suppressing mTOR signaling
2014
Hepatic triacylglycerol accumulation and insulin resistance
2008
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Genetic determinants of hepatic steatosis in man
2011
Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice
2013
SIRT6 protects against pathological damage caused by diet‐induced obesity
2009
Deficiency of liver adipose triglyceride lipase in mice causes progressive hepatic steatosis
2011
mTOR Signaling in Growth Control and Disease
2012 Standout
Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
2009
TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop
2013
A survey of chemical methods for sugar-nucleotide synthesis
2009
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Sirtuin 1 in lipid metabolism and obesity
2011
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity
2013 StandoutNobel
The genetics of ageing
2010 StandoutNature
Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds
2016
The role of pathway-selective insulin resistance and responsiveness in diabetic dyslipoproteinemia
2012
Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
2017
Liver Injury and Disease Pathogenesis in Chronic Hepatitis C
2013
Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal
2009
Hallmarks of aging: An expanding universe
2023 Standout
Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)
2008
Calorie restriction effects on silencing and recombination at the yeast rDNA
2009
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
2014 Nature
Dissociating fatty liver and diabetes
2012
Conserved Metabolic Regulatory Functions of Sirtuins
2008
Sirtuins, Aging, and Medicine
2011
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles
2009 StandoutNobel
Silencing of Hepatic Fatty Acid Transporter Protein 5 in Vivo Reverses Diet-induced Non-alcoholic Fatty Liver Disease and Improves Hyperglycemia
2008
Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction
2010
Sirtuins, Aging, and Metabolism
2011
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
2008 Standout
The multifaceted functions of sirtuins in cancer
2015
The NAD World: A New Systemic Regulatory Network for Metabolism and Aging—Sirt1, Systemic NAD Biosynthesis, and Their Importance
2009
Insulin sensitivity: modulation by nutrients and inflammation
2008
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
2008
Mitochondrial longevity pathways
2010
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Obesity and Nonalcoholic Fatty Liver Disease: Biochemical, Metabolic, and Clinical Implications
2009 Standout
Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice
2010
Mechanisms of NAFLD development and therapeutic strategies
2018 Standout
Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases
2012
C. elegans dauer formation and the molecular basis of plasticity
2008
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
2012
Non-alcoholic fatty liver disease
2021 Standout
2-Oleoyl Glycerol Is a GPR119 Agonist and Signals GLP-1 Release in Humans
2011
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization
2008 Nature
The Problem of Establishing Relationships between Hepatic Steatosis and Hepatic Insulin Resistance
2012
SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice
2008
Roles of Diacylglycerols and Ceramides in Hepatic Insulin Resistance
2017
Prediction of C. elegans Longevity Genes by Human and Worm Longevity Networks
2012 StandoutNobel
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
SIRT1: recent lessons from mouse models
2010
Pharmacological inhibition of diacylglycerol acyltransferase 1 reduces body weight gain, hyperlipidemia, and hepatic steatosis in db/db mice
2010
Metabolic adaptations through the PGC‐1α and SIRT1 pathways
2007
Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice
2008
Insulin resistance, inflammation, and non-alcoholic fatty liver disease
2008
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Mitochondrial Overload and Incomplete Fatty Acid Oxidation Contribute to Skeletal Muscle Insulin Resistance
2008 Standout
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
2008
AMP-activated protein kinase and its downstream transcriptional pathways
2010
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
2012
Risk of Cardiovascular Disease in Patients with Nonalcoholic Fatty Liver Disease
2010 Standout
Autophagy and Aging
2011 Standout
A Common Variant in the Patatin-Like Phospholipase 3 Gene ( PNPLA3 ) Is Associated with Fatty Liver Disease in Obese Children and Adolescents
2010
The ChEMBL database in 2017
2016 Standout
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
2009
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
2010
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Caloric restriction mimetics: towards a molecular definition
2014
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
The Hallmarks of Aging
2013 Standout
Seven-transmembrane receptors
2002 StandoutNobel
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
SIRT1 Negatively Regulates the Mammalian Target of Rapamycin
2010
Time-dependent effects of Prkce deletion on glucose homeostasis and hepatic lipid metabolism on dietary lipid oversupply in mice
2011
Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease
2016
Long-term effects of high-fat or high-carbohydrate diets on glucose tolerance in mice with heterozygous carnitine palmitoyltransferase-1a deficiency
2011
SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
2009
Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction
2011
The Aging Stress Response
2010
Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?
2008
PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
2009
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
2012
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
2015
Antibacterial drug discovery in the resistance era
2016 StandoutNature
Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis
2010
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
2010
Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis
2015
TORC2 Regulates Hepatic Insulin Signaling via a Mammalian Phosphatidic Acid Phosphatase, LIPIN1
2009
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity
2010
Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport
2011
Causes and Metabolic Consequences of Fatty Liver
2008
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation
2012
Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice
2008
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
A Role of the Bile Salt Receptor FXR in Atherosclerosis
2010
Sirt1 protects against high-fat diet-induced metabolic damage
2008
Regulation of the aging process by autophagy
2009
Carnitine Palmitoyltransferase (CPT) Modulators: A Medicinal Chemistry Perspective on 35 Years of Research
2011
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene
2009
The bacterial cell wall as a source of antibacterial targets
2002
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
Spermidine in health and disease
2018 StandoutScience
Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver
2017
PPAR.BETA./.DELTA. regulates the human SIRT1 gene transcription via Sp1
2010
Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2
2011
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues
2010 StandoutNobel
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Dauer larva quiescence alters the circuitry of microRNA pathways regulating cell fate progression inC. elegans
2012 StandoutNobel
Inhibition of De Novo Ceramide Synthesis Reverses Diet-Induced Insulin Resistance and Enhances Whole-Body Oxygen Consumption
2010
Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1+/− Mice: A Role of Lipid Mobilization and Inflammation
2010
Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice
2014
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Extending Healthy Life Span—From Yeast to Humans
2010 StandoutScience
Challenges of Antibacterial Discovery
2011
Does Diacylglycerol Accumulation in Fatty Liver Disease Cause Hepatic Insulin Resistance?
2015
Chemical Glycoproteomics
2016 StandoutNobel
Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance
2016
Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
2008
Works of Stephen Marmor being referenced
Dissociation of Hepatic Steatosis and Insulin Resistance in Mice Overexpressing DGAT in the Liver
2007
Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding
2009
Inhibitors of the bacterial cell wall biosynthesis enzyme MurC
2001
SIRT1 transgenic mice show phenotypes resembling calorie restriction
2007