Citation Impact
Citing Papers
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
2010 StandoutNobel
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
2009 StandoutScience
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor
2002 StandoutScience
Glucocorticoids Promote Nonphlogistic Phagocytosis of Apoptotic Leukocytes
1999
The Required Role of Endogenously Produced Lipoxin A4 and Annexin-1 for the Production of IL-10 and Inflammatory Hyporesponsiveness in Mice
2007
Lipid mediators in immune dysfunction after severe inflammation
2013
Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury
2001
Gout: On the brink of novel therapeutic options for an ancient disease
2004
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
POLY(ADP-RIBOSE) SYNTHETASE INHIBITION PREVENTS LIPOPOLYSACCHARIDE-INDUCED PEROXYNITRITE MEDIATED DAMAGE IN DIAPHRAGM
2002
Gout and hyperuricemia
2002
The physiology and pathophysiology of nitric oxide in the brain
2005
Gout-associated uric acid crystals activate the NALP3 inflammasome
2006 StandoutNature
A Novel Ligand of the Formyl Peptide Receptor
2000
ANNEXIN I IS STORED WITHIN GELATINASE GRANULES OF HUMAN NEUTROPHIL AND MOBILIZED ON THE CELL SURFACE UPON ADHESION BUT NOT PHAGOCYTOSIS
2000
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
2011 StandoutNobel
MC4R Agonists: Structural Overview on Antiobesity Therapeutics
2018 StandoutNobel
Melanocortin Signalling Mechanisms
2010
Differential Modulation of Annexin I Binding Sites on Monocytes and Neutrophils
1999
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Poly(ADP-ribose) synthetase activation mediates increased permeability induced by peroxynitrite in Caco-2BBe cells
1998
Role of poly(ADP-ribose) synthetase activation in the development of experimental allergic encephalomyelitis
2001
Roles of poly(ADP-ribose) polymerase activation in the pathogenesis of diabetes mellitus and its complications
2005
Protective effect of a novel, potent inhibitor of poly(adenosine 5′-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis*
2002
Poly(ADP-ribose) polymerase activation by reactive nitrogen species—Relevance for the pathogenesis of inflammation
2005
Cyclic analogs of α-melanocyte-stimulating hormone (αMSH) with high agonist potency and selectivity at human melanocortin receptor 1b
2008
Shared Principles in NF-κB Signaling
2008 Standout
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Activation of the peroxynitrite-poly(adenosine diphosphate-ribose) polymerase pathway during neointima proliferation: A new target to prevent restenosis after endarterectomy
2006
Poly (ADP-ribose) synthetase activation mediates pulmonary microvascular and intestinal mucosal dysfunction in endotoxin shock
1998
Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs
2012
Shock, inflammation and PARP
2005
Proteomic profiling identifies breast tumor metastasis‐associated factors in an isogenic model
2007
Poly(ADP-Ribose) Polymerase Inhibition in Oxidant-Stressed Endothelial Cells Prevents Oncosis and Permits Caspase Activation and Apoptosis
1999
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Protective effects of 5-iodo-6-amino-1,2-benzopyrone, an inhibitor of poly(ADP-ribose) synthetase against peroxynitrite-induced glial damage and stroke development
1998
Nonresolving Inflammation
2010 Standout
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichiacolimeningitis in the newborn piglet
2001
The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors
2002 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Oxidative stress and regional ischemia-reperfusion injury: the peroxynitrite–poly(ADP-ribose) polymerase connection
2003
Poly(ADP‐Ribose) Synthase Inhibition Reduces Ischemic Injury and Inflammation in Neonatal Rat Brain
2000
Poly(ADP-ribose) polymerase activation in the reperfused myocardium
2004
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors
2005
Blockade of poly(ADP-ribose) synthetase inhibits neutrophil recruitment, oxidant generation, and mucosal injury in murine colitis
1999
The melanocortin receptors and their accessory proteins
2013
A Novel Method for Isolation of Neutrophils from Murine Blood Using Negative Immunomagnetic Separation
2001
Missing Pieces in the NF-κB Puzzle
2002 Standout
Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways
2004
Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death
2001
Inhibitors of the activity of poly (ADP‐ribose) synthetase reduce the cell death caused by hydrogen peroxide in human cardiac myoblasts
1998
Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat
2005
DNA Damage Induced by Peroxynitrite: Subsequent Biological Effects
1997
Regulation of microglial expression of integrins by poly(ADP-ribose) polymerase-1
2001
Phagocytosis of apoptotic cells and the resolution of inflammation
2003
Role of poly(adenosine diphosphate???ribose) polymerase 1 in septic peritonitis
2003
Physiological roles of the melanocortin MC3 receptor
2011
Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis
2001
Gout
2016 Standout
Mechanisms of inflammation in gout
2005
Regulation of Leukocyte‐Endothelial Interactions by Glucocorticoids
2002
Inhibitors of poly (ADP-ribose) synthetase protect rat cardiomyocytes against oxidant stress
1999
Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment
2001
Activation of Poly(ADP-Ribose) Polymerase Contributes to Development of Doxorubicin-Induced Heart Failure
2002
The role of proopiomelanocortin (POMC) neurones in feeding behaviour
2007
Benzamide, a Poly(ADP‐Ribose) Polymerase Inhibitor, Is Neuroprotective against Soman‐Induced Seizure‐Related Brain Damagea
1999
Mast cell‐expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis
2006
Lipoxins: resolutionary road
2009
Poly(ADP-ribose): novel functions for an old molecule
2006 Standout
The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders
2002
Endogenous mediators that inhibit the leukocyte– endothelium interaction
1997
Differentiation of Phagocytic Monocytes into Lymph Node Dendritic Cells In Vivo
1999 StandoutNobel
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Resolution of inflammation: a new therapeutic frontier
2016
Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity
2007
Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol
2006 Standout
Origin and physiological roles of inflammation
2008 StandoutNature
Gout
2003
Therapeutic potential of superoxide dismutase mimetics as therapeutic agents in critical care medicine
2003
The Pathophysiology and Treatment of Sepsis
2003 Standout
The Inflammasomes
2010 Standout
Sod mimetics are coming of age
2002
Novel phenanthridinone inhibitors of poly(adenosine 5′-diphosphate-ribose) synthetase: Potent cytoprotective and antishock agents*
2002
Peroxynitrite‐induced thymocyte apoptosis: the role of caspases and poly (ADP‐ribose) synthetase (PARS) activation
1998
Protective effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in paw oedema induced by carrageenan in the rat
1999
Correlation between the Antiinflammatory Protein Annexin 1 (Lipocortin 1) and Serum Cortisol in Subjects with Normal and Dysregulated Adrenal Function
2005
Cellular Responses to DNA Damage in the Absence of Poly(ADP-ribose) Polymerase
1998
Febuxostat Compared with Allopurinol in Patients with Hyperuricemia and Gout
2005 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Cardiovascular effects of melanocortins
2011
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema
1999
Synovial mast cells: role in acute and chronic arthritis
2007
Oxidative stress and accelerated vascular aging: implications for cigarette smoking
2009
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Calcium Signaling
2007 Standout
Expression of mitogen‐activated protein kinase phosphatase 1, a negative regulator of the mitogen‐activated protein kinases, in rheumatoid arthritis: Up‐regulation by interleukin‐1β and glucocorticoids
2004
The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R)
2005
Annexin A1 and glucocorticoids as effectors of the resolution of inflammation
2008
Role of poly-(ADP-ribose) synthetase in lipopolysaccharide-induced vascular failure and acute lung injury in pigs
2000
Lipocortin 1 and Chemokine Modulation of Granulocyte and Monocyte Accumulation in Experimental Inflammation
1998
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury
2002
GPI 6150, a poly (ADP-ribose) polymerase inhibitor, exhibits an anti-inflammatory effect in rat models of inflammation
2001
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Role of poly(ADP-ribose) synthetase in inflammation and ischaemia–reperfusion
1998
Exploring the full spectrum of macrophage activation
2008 Standout
Inhibition of poly(ADP‐ribose) synthetase (PARS) and protection against peroxynitrite‐induced cytotoxicity by zinc chelation
1999
Myocardial protection by PJ34, a novel potent poly (ADP-ribose) synthetase inhibitor
2002
Activator protein‐1 signalling pathway and apoptosis are modulated by poly(ADP‐ribose) polymerase‐1 in experimental colitis
2004
Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig
1998
Modulation of experimental autoimmune encephalomyelitis by endogenous Annexin A1
2009
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
2011 StandoutNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Management of Acute and Chronic Gouty Arthritis
2004
Annexins: linking Ca2+ signalling to membrane dynamics
2005
Inflammasomes in health and disease
2012 StandoutNature
Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3
2016
Role of poly(ADP-ribose) polymerase activation in endotoxin-induced cardiac collapse in rodents
2002
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
2003
Requirement of Intracellular Calcium Mobilization for Peroxynitrite-Induced Poly(ADP-Ribose) Synthetase Activation and Cytotoxicity
1999
New inhibitors of poly(ADP-ribose) polymerase and their potential therapeutic targets
2002
Poly(ADP-ribose) synthetase activation mediates mitochondrial injury during oxidant-induced cell death.
1998
Part II: Beneficial Effects of the Peroxynitrite Decomposition Catalyst FP15 in Murine Models of Arthritis and Colitis
2002
Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice
2015
Resolution of Acute Inflammation in the Lung
2013
Inhibition of PARS attenuates endotoxin-induced dysfunction of pulmonary vasorelaxation
1999
Promoting detachment of neutrophils adherent to murine postcapillary venules to control inflammation: Effect of lipocortin 1
1998
The resolution of inflammation: the devil in the flask and in the details
2011
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways
2010
Quality Control by DNA Repair
1999 StandoutScienceNobel
Beneficial effects of Mn(III)tetrakis (4‐benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in zymosan‐induced shock
1999
Genetic Disruption of Poly (ADP-Ribose) Synthetase Inhibits the Expression of P-Selectin and Intercellular Adhesion Molecule-1 in Myocardial Ischemia/Reperfusion Injury
1998
Inhibition of Poly(ADP-Ribose) Polymerase Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage in Rabbits
2001
Annexin 1 Binds to U937 Monocytic Cells and Inhibits Their Adhesion to Microvascular Endothelium: Involvement of the α4β1 Integrin
2000
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Obesity-Induced Inflammation in White Adipose Tissue Is Attenuated by Loss of Melanocortin-3 Receptor Signaling
2007
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles
2013
Cytokine Storm
2020 Standout
Poly(ADP-Ribose) Polymerase Inhibition Reduces Reperfusion Injury After Heart Transplantation
2002
Protection against peroxynitrite-induced fibroblast injury and arthritis development by inhibition of poly(ADP-ribose) synthase
1998
Transcriptional regulation of the human FPR2/ALX gene: evidence of a heritable genetic variant that impairs promoter activity
2011
Poly(ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion
1999
A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation
2013
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Role of Free Radicals and Poly(ADP-ribose) Synthetase in Intestinal Tight Junction Permeability
2000
Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model
1998
Stabilization of Salivary Biomarkers
2021
Annexins: From Structure to Function
2002 Standout
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
2010
TAPping into mRNA Export
2001 StandoutScienceNobel
The Microcirculation and Inflammation: Site of Action for Glucocorticoids
2000
Lipocortin 1 reduces myocardial ischemia‐reperfusion injury by affecting local leukocyte recruitment
2000
Beneficial effects of tempol, a membrane-permeable radical scavenger, on the multiple organ failure induced by zymosan in the rat
2001
Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia
2002
Design, Synthesis, and Evaluation of Proline and Pyrrolidine Based Melanocortin Receptor Agonists. A Conformationally Restricted Dipeptide Mimic Approach
2006
Effects of Low-Dose Aspirin on Acute Inflammatory Responses in Humans
2009
Reshaping de Novo Protein Switches into Bioresponsive Materials for Biomarker, Toxin, and Viral Detection
2022 StandoutNobel
Meningitis-Associated Central Nervous System Complications are Mediated by the Activation of Poly(ADP-ribose) Polymerase
2002
Molecular Circuits of Resolution: Formation and Actions of Resolvins and Protectins
2005
Resolution Phase of Inflammation: Novel Endogenous Anti-Inflammatory and Proresolving Lipid Mediators and Pathways
2006
Regulatory Mechanism and Physiological Role of Cytosolic Phospholipase A2
2004
Selective Inhibition of NF-κB Activation by a Peptide That Blocks the Interaction of NEMO with the IκB Kinase Complex
2000 Science
Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia
2004
Myocardial Ischemic Preconditioning in Rodents Is Dependent on Poly (ADP-Ribose) Synthetase
2001
Purines inhibit poly(ADP‐ribose) polymerase activation and modulate oxidant‐induced cell death
2001
Proton-Coupled Electron Transfer
2012 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Poly(ADP-Ribose) Synthetase Activation Mediates Mitochondrial Injury During Oxidant-Induced Cell Death
1998
Works of Stephen J. Getting being referenced
Melanocortin receptor signaling in RAW264.7 macrophage cell line
2005
Subacute Treatment of Rats with Dexamethasone Reduces ICAM-1 Levels on Circulating Monocytes
1997
Agonism at melanocortin receptor type 3 on macrophages inhibits neutrophil influx
1999
Chondroprotective and anti‐inflammatory role of melanocortin peptides in TNF‐α activated human C‐20/A4 chondrocytes
2012
Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1
1997
A role for MC3R in modulating lung inflammation
2008
Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen‐induced arthritis
2004
Targeting melanocortin receptors as potential novel therapeutics
2006
Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor
2002
[d-Trp8]-γ-Melanocyte-Stimulating Hormone Exhibits Anti-Inflammatory Efficacy in Mice Bearing a Nonfunctional MC1R (Recessive Yellow e/e Mouse)
2006
Biphasic modulation of GABA release by nitric oxide in the hippocampus of freely moving rats in vivo
1996
Activation of melanocortin type 3 receptor as a molecular mechanism for adrenocorticotropic hormone efficacy in gouty arthritis
2002
Anti-inflammatory effects of a novel, potent inhibitor of poly (ADP-ribose) polymerase
2001
Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury
2014
Aberrant inflammation and resistance to glucocorticoids in Annexin 1 −/− Mouse
2002
Inhibition of poly (ADP-ribose) Synthetase Attenuates Neutrophil Recruitment and Exerts Antiinflammatory Effects
1997
Melanocortin 3 receptors control crystal‐induced inflammation
2006
Annexin 1 and Melanocortin Peptide Therapy for Protection Against Ischaemic-Reperfusion Damage in the Heart
2006
Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis
2010
Involvement of the Receptor for Formylated Peptides in the in Vivo Anti-Migratory Actions of Annexin 1 and its Mimetics
2001
POMC Gene-Derived Peptides Activate Melanocortin Type 3 Receptor on Murine Macrophages, Suppress Cytokine Release, and Inhibit Neutrophil Migration in Acute Experimental Inflammation
1999
Leukocyte recruitment in the brain in sepsis: involvement of the annexin 1‐FPR2/ALX anti‐inflammatory system
2012
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor‐null mice after ischemia‐reperfusion
2008
MC3-R as a novel target for antiinflammatory therapy.
2000
Saliva: Physiology and Diagnostic Potential in Health and Disease
2010
Molecular Determinants of Monosodium Urate Crystal-Induced Murine Peritonitis: A Role for Endogenous Mast Cells and a Distinct Requirement for Endothelial-Derived Selectins
1997
Natural and synthetic agonists of the melanocortin receptor type 3 possess anti-inflammatory properties
2001
Redundancy of a Functional Melanocortin 1 Receptor in the Anti-inflammatory Actions of Melanocortin Peptides: Studies in the Recessive Yellow (e/e) Mouse Suggest an Important Role for Melanocortin 3 Receptor
2003
Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics.
2001
Melanocortin peptides and their receptors: new targets for anti-inflammatory therapy
2002
The annexin-1 knockout mouse: what it tells us about the inflammatory response.
2002