Citation Impact
Citing Papers
Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II
2004
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients
2015
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Insulin-induced remission in new-onset NOD mice is maintained by the PD-1–PD-L1 pathway
2006
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Effective expansion of alloantigen-specific Foxp3 + CD25 + CD4 + regulatory T cells by dendritic cells during the mixed leukocyte reaction
2006 StandoutNobel
Anti-Islet Autoantibodies Trigger Autoimmune Diabetes in the Presence of an Increased Frequency of Islet-Reactive CD4 T Cells
2011
Locus control regions: coming of age at a decade plus
1999
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The accelerator hypothesis: a review of the evidence for insulin resistance as the basis for type I as well as type II diabetes
2009
Severe impairment of bone mass and turnover in Cushing’s disease: comparison between childhood‐onset and adulthood‐onset disease
2002
Final adult height and body mass index after cure of paediatric Cushing's disease
2005
Genetics of Type 1A Diabetes
2009
The desmopressin test as a predictive factor of outcome after pituitary surgery for Cushing's disease
2004
Immune cell crosstalk in type 1 diabetes
2010
Mice lackingBmp6 function
1998
Factors influencing cure by transsphenoidal selective adenomectomy in paediatric Cushing’s disease
2005
Diabetes-related antibodies in euglycemic subjects
2005
A Comprehensive Review of Interventions in the NOD Mouse and Implications for Translation
2005
Domain-specific mutations in TGFB1 result in Camurati-Engelmann disease
2000
Autoimmune Polyendocrine Syndromes
2004
Treatment of Cushing’s Disease: A Retrospective Clinical Study of the Latest 100 Cases
2006
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
2006 StandoutNobel
Incidence and Late Prognosis of Cushing’s Syndrome: A Population-Based Study1
2001
Cushing's syndrome
2015 Standout
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
1998 Standout
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
Etiology of Type 1 Diabetes
2010
Long‐term follow‐up results of transsphenoidal surgery for Cushing’s disease in a single centre using strict criteria for remission
2002
Paediatric Cushing's syndrome: epidemiology, investigation and therapeutic advances
2007
Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development
1997 Standout
Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs
2006
Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survival
2001
Dynamics of Serum Cortisol Levels after Transsphenoidal Surgery in a Cohort of Patients with Cushing’s Disease
2004
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
Treatment of pituitary‐dependent Cushing's syndrome: long‐term results of unilateral adrenalectomy followed by external pituitary irradiation compared to transsphenoidal pituitary surgery
2000
Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia
1997 Standout
Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial
2011
Genetics, pathogenesis and clinical interventions in type 1 diabetes
2010 Nature
Inducing and Administering Tregs to Treat Human Disease
2016
The replication of β cells in normal physiology, in disease and for therapy
2007
TGF-β-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
2003
Relative Contributions of Inferior Petrosal Sinus Sampling and Pituitary Imaging in the Investigation of Children and Adolescents with ACTH-Dependent Cushing’s Syndrome
2001
Regulatory T cells in autoimmune disease
2018
Recapitulation of signals regulating embryonic bone formation during postnatal growth and in fracture repair
1998
The Pathogenesis and Natural History of Type 1 Diabetes
2012
Absence of peritumoral Crooke’s change is associated with recurrence in surgically treated Cushing’s disease
2000
Type 1 diabetes: recent developments
2004
Extracellular Matrix Molecules and their Receptors: Functions in Neural Development
1991
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
1999 Standout
GAD Treatment and Insulin Secretion in Recent-Onset Type 1 Diabetes
2008
Sox9 is required for cartilage formation
1999 Standout
The regulation of immune tolerance by FOXP3
2017
T cell–directed therapies: lessons learned and future prospects
2006
Achieving Antigen-Specific Tolerance in Diabetes: Regulating Specifically
2005
Cushing’s Disease in Childhood: Presentation, Investigation, Treatment and Long-Term Outcome
2001
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Antigen-specific therapeutic approaches for autoimmunity
2019
Transsphenoidal pituitary surgery via the endoscopic technique: results in 35 consecutive patients with Cushing’s disease
2006
Localization of pituitary adenomas by using intraoperative ultrasoound pituitary in patients with Cushing's disease and no demonstrable tumor on magnetic resonance imaging
1998
Diagnosis and treatment of pediatric Cushing’s disease
2007
Bone morphogenetic proteins: multifunctional regulators of vertebrate development.
1996 Standout
GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus
2012
Control of TH17 cells occurs in the small intestine
2011 Nature
The stages of type 1A diabetes: 2005
2005
Mechanisms of immunological tolerance
2015
The Stages of Type 1A Diabetes
2005
Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor
2016
Harnessing the plasticity of CD4+ T cells to treat immune-mediated disease
2016
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation
2017
Type 1 diabetes
2013 Standout
Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage
1997
Regulatory T cells in transplantation tolerance
2003 StandoutNobel
Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth
1996
BMPs as Mediators of Roof Plate Repulsion of Commissural Neurons
1999
Prevention of type 1 diabetes: the time has come
2008
Targeting Treg signaling for the treatment of autoimmune diseases
2015
Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
2007
Past, Present, and Future of Regulatory T Cell Therapy in Transplantation and Autoimmunity
2019
A historical view from thirty eventful years of immunotherapy in autoimmune diabetes
2011
Effect of heat shock protein peptide DiaPep277 on ß‐cell function in paediatric and adult patients with recent‐onset diabetes mellitus type 1: two prospective, randomized, double‐blind phase II trials
2006
Diabetogenic T lymphocytes in human Type 1 diabetes
2011
Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: a prospective study
2003
Bone mineral density at diagnosis and following successful treatment of pediatric Cushing’s disease
2005
Immune intervention in type 1 diabetes
2011
Clinical and Endocrine Responses to Pituitary Radiotherapy in Pediatric Cushing’s Disease: An Effective Second-Line Treatment
2003
Clinical Applications of Diabetes Antibody Testing
2009
Regulation of chondrocyte differentiation by Cbfa1
1999
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
Interleukin‐10‐secreting type 1 regulatory T cells in rodents and humans
2006
Growth factors for bone growth and repair: IGF, TGFβ and BMP
1996
Adoptive Transfer of Regulatory T Cells as a Promising Immunotherapy for the Treatment of Multiple Sclerosis
2019
Immunosuppressive Drugs for Kidney Transplantation
2004 Standout
C-Peptide Levels and Insulin Independence Following Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
2009
Type 1 diabetes as a relapsing–remitting disease?
2007
CD4+ regulatory T cells in autoimmunity and allergy
2002
Therapeutic approaches to allergy and autoimmunity based on FoxP3+ regulatory T-cell activation and expansion
2009 StandoutNobel
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection
2016
Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+CD25−LAP+ T cells
2006
TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs
2005
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Free Ca2+ and cytoplasmic streaming in the alga Chara
1982 Nature
The Application of the Diabetes Prevention Trial–Type 1 Risk Score for Identifying a Preclinical State of Type 1 Diabetes
2012
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Dendritic cells with TGF-β1 differentiate naïve CD4+CD25−T cells into islet-protective Foxp3+regulatory T cells
2007 StandoutNobel
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Hif-1α regulates differentiation of limb bud mesenchyme and joint development
2007
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Regulatory T Cells and Human Disease
2020 StandoutNobel
Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.
1996
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
2016
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
CD4+CD25+ T Regulatory Cells Dependent on ICOS Promote Regulation of Effector Cells in the Prediabetic Lesion
2004
How Does Type 1 Diabetes Develop?
2011
Colony Inhibition of Fibroblasts from Chimeric Dogs Mediated by the Dogs' Own Lymphocytes and Specifically Abrogated by Their Serum
1970 StandoutNobel
Autoimmune Markers in Diabetes
2010
Cure of Overt Diabetes in NOD Mice by Transient Treatment With Anti-Lymphocyte Serum and Exendin-4
2004
Parathyroid hormone-related protein and Indian hedgehog control the pace of cartilage differentiation.
1997
Transsphenoidal surgery for Cushing's disease: a review of success rates, remission predictors, management of failed surgery, and Nelson's Syndrome
2007
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
2006 Standout
Quality of Life and Other Outcomes in Children Treated for Cushing Syndrome
2013
Transforming Growth Factor-β1 to the Bone
2005
Adaptive TGF-β-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment
2007
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation
1998
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Translational Mini-Review Series on Type 1 Diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
2007
Recent Lessons Learned From Prevention and Recent-Onset Type 1 Diabetes Immunotherapy Trials
2012
Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
1997
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
THE NOD MOUSE: A Model of Immune Dysregulation
2004
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3
1998
Genomic analysis of orthologous mouse and human olfactory receptor loci
2001 StandoutNobel
Through the Fog: Recent Clinical Trials to Preserve β-Cell Function in Type 1 Diabetes
2012
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
The Programmed Death-1 (PD-1) Pathway Regulates Autoimmune Diabetes in Nonobese Diabetic (NOD) Mice
2003
Bone Morphogenetic Proteins, Their Antagonists, and the Skeleton
2003
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
2011
Heterogeneity of T1DM raises questions for therapy
2011
Uncompensated polyuria in a mouse model of Bartter's syndrome
2000 StandoutNobel
Type 1 Diabetes Immunotherapy: Is the Glass Half Empty or Half Full?
2011
Update in Type 1 Diabetes
2007
Latent Autoimmune Diabetes in Adults
2009
Prepubertal Cushing’s Disease Is More Common in Males, But There Is No Increase in Severity at Diagnosis
2004
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
1996 StandoutNobel
Exceedingly small iron oxide nanoparticles as positive MRI contrast agents
2017 StandoutNobel
Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein
1996 StandoutScience
Increased expression of TGF-beta 2 in osteoblasts results in an osteoporosis-like phenotype.
1996
Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome
1995 StandoutNobel
Treatment with Nonmitogenic Anti-CD3 Monoclonal Antibody Induces CD4+ T Cell Unresponsiveness and Functional Reversal of Established Experimental Autoimmune Encephalomyelitis
2005
Cytoplasmic calcium regulates voltage-dependent ion channels in plant vacuoles
1987 StandoutNatureNobel
Antigen-Specific FoxP3-Transduced T-Cells Can Control Established Type 1 Diabetes
2005
Works of Stephen E. Gitelman being referenced
Fall in C-Peptide During First 2 Years From Diagnosis
2012
Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years
2009
Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus
2002
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial
2011
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial
2011
Toward a molecular understanding of skeletal development
1995
Peptide mapping and characterisation of glycation patterns of the glima 38 antigen recognised by autoantibodies in Type I diabetic patients
2000
Nephrogenic Syndrome of Inappropriate Antidiuresis
2005
A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?
1995
Structure and sequence of the mouse bmp6 gene
1997
Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function
2009
Long-Term Outcome in Children and Adolescents after Transsphenoidal Surgery for Cushing’s Disease1
1997
Costimulation Modulation With Abatacept in Patients With Recent-Onset Type 1 Diabetes: Follow-up 1 Year After Cessation of Treatment
2013
Immune Therapy and β-Cell Death in Type 1 Diabetes
2013
Recombinant Vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo.
1994
Purification of calmodulin from Chlamydomonas: calmodulin occurs in cell bodies and flagella.
1980
A Single Course of Anti-CD3 Monoclonal Antibody hOKT3γ1(Ala-Ala) Results in Improvement in C-Peptide Responses and Clinical Parameters for at Least 2 Years after Onset of Type 1 Diabetes
2005
Vgr-1/BMP-6 induces osteoblastic differentiation of pluripotential mesenchymal cells.
1995
Teplizumab (Anti-CD3 mAb) Treatment Preserves C-Peptide Responses in Patients With New-Onset Type 1 Diabetes in a Randomized Controlled Trial
2013
Inhibition of TGF-β receptor signaling in osteoblasts leads to decreased bone remodeling and increased trabecular bone mass
1999
Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.
1989
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
2015
Insulin Secretion in Type 1 Diabetes
2004
Analysis of T-Cell Assays to Measure Autoimmune Responses in Subjects With Type 1 Diabetes
2006
Abundant adrenal-specific transcription of the human P450c21A “pseudogene”
1993
B-Lymphocyte Depletion With Rituximab and β-Cell Function: Two-Year Results
2013