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Citing Papers
Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma
2008
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Primary Tumor Response to Preoperative Chemoradiation With or Without Oxaliplatin in Locally Advanced Rectal Cancer: Pathologic Results of the STAR-01 Randomized Phase III Trial
2011
Parkinson-like syndrome induced by continuous MPTP infusion: Convergent roles of the ubiquitin-proteasome system and α-synuclein
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2009
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
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Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu 5 ) X-ray Structures
2018
Computational design of soluble and functional membrane protein analogues
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Ionotropic and metabotropic glutamate receptor structure and pharmacology
2005
Pharmacology of AMPA/Kainate Receptor Ligands and Their Therapeutic Potential in Neurological and Psychiatric Disorders
2000
Pharmacological Properties of the Potent Epileptogenic Amino Acid Dysiherbaine, a Novel Glutamate Receptor Agonist Isolated from the Marine Sponge Dysidea herbacea
2001
An orthotopic colon cancer model for studying the B7-H3 antitumor effect in vivo
2006
Binding of an AMPA receptor potentiator ([3H]LY395153) to native and recombinant AMPA receptors1The first two authors contributed equally to this work.1
2001
Glutamate receptor ion channels
2005 Standout
N-Methyl-d-aspartate (NMDA) Receptor Subunit NR1 Forms the Substrate for Oligomeric Assembly of the NMDA Receptor
2007
G Protein-Coupled Receptor Allosterism and Complexing
2002
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Breast cancer expresses functional NMDA receptors
2009
Psoriasis
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Characterization of the binding of two novel glycine site antagonists to cloned NMDA receptors: evidence for two pharmacological classes of antagonists
2000
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Synthesis of streptavidin-FITC-conjugated core–shell Fe3O4-Au nanocrystals and their application for the purification of CD4+ lymphocytes
2008
Pathogenesis and clinical features of psoriasis
2007 Standout
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
The Risk of Lymphoma in Patients with Psoriasis
2006
Activation of recombinant NR1/NR2C NMDA receptors
2008
2-{2-[3-(Pyridin-3-yloxy)phenyl]-2H-tetrazol-5-yl}pyridine: a highly potent, orally active, metabotropic glutamate subtype 5 (mGlu5) receptor antagonist
2004
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Characterization of a Metabotropic Glutamate Receptor Type 5-Green Fluorescent Protein Chimera (mGluR5–GFP): Pharmacology, Surface Expression, and Differential Effects of Homer-1a and Homer-1c
2001
Ethanol and neurotransmitter interactions—from molecular to integrative effects
1998
Colorectal cancer
2013 Standout
Rationale for and use of NMDA receptor antagonists in Parkinson's disease
2004
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Cloning and expression of the human NMDA receptor subunit NR3B in the adult human hippocampus
2004
Psoriasis
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Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
2008
Glial and neuronal control of brain blood flow
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Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Direct In Vivo Xenograft Tumor Model for Predicting Chemotherapeutic Drug Response in Cancer Patients
2008
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Identification of Molecular Determinants That Are Important in the Assembly of N-Methyl-d-aspartate Receptors
2001
Dual MAP kinase pathways mediate opposing forms of long-term plasticity at CA3–CA1 synapses
2000
Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2
2005
Cloning and characterization of promoter and 5′-UTR of the NMDA receptor subunit ϵ2: evidence for alternative splicing of 5′-non-coding exon
1998
Subtypes of NMDA receptors in new‐born rat hippocampal granule cells
2002
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation
2002
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Nucleotide Sequence, Genomic Organization, and Chromosomal Localization of Genes Encoding the Human NMDA Receptor Subunits NR3A and NR3B
2001
Glutamate-based therapeutic approaches: NR2B receptor antagonists
2005
LTP and LTD
2004 Standout
Pancreatic Cancer
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Protective and pathogenic functions of macrophage subsets
2011 Standout
Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Contributes to the Development of Nigro-Striatal Damage Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice
2004
Biaryl Phosphane Ligands in Palladium‐Catalyzed Amination
2008 Standout
Equilibrium Constants for (R)-[(S)-1-(4-Bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic Acid (NVP-AAM077) Acting at Recombinant NR1/NR2A and NR1/NR2B N-Methyl-d-aspartate Receptors: Implications for Studies of Synaptic Transmission
2006
Cytotoxic T-cell and NK-cell Lymphomas
2014
Astrocyte–endothelial interactions at the blood–brain barrier
2005 Standout
A novel, competitive mGlu5 receptor antagonist (LY344545) blocks DHPG‐induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices
2000
[3H]-Methoxymethyl-MTEP and [3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor
2003
Structural Bases of Desensitization in AMPA Receptor-Auxiliary Subunit Complexes
2017 StandoutNobel
Polyethylene glycol-based homologated ligands for nicotinic acetylcholine receptors
2008
Glutamate Receptor Gating
2004
Exploring the full spectrum of macrophage activation
2008 Standout
Anti-TNF Antibody Therapy in Rheumatoid Arthritis and the Risk of Serious Infections and Malignancies
2006 Standout
Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors
2004 StandoutNobel
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
2007 Standout
Functional NR2B‐ and NR2D‐containing NMDA receptor channels in rat substantia nigra dopaminergic neurones
2005
Recent advances in Sonogashira reactions
2011 Standout
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma
2009 Standout
Discovery of Molecular Switches That Modulate Modes of Metabotropic Glutamate Receptor Subtype 5 (mGlu5) Pharmacology in Vitro and in Vivo within a Series of Functionalized, Regioisomeric 2- and 5-(Phenylethynyl)pyrimidines
2009
Copper Active Sites in Biology
2014 Standout
Macrophages Sequentially Change Their Functional Phenotype in Response to Changes in Microenvironmental Influences
2005
Hemocyanin Function in Active and Dormant Land Snails, Otala lactea
1986
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Metabotropic glutamate receptors as a strategic target for the treatment of epilepsy
2006
Small molecule modulation of Smoothened activity
2002 Standout
Ethanol-Induced Apoptotic Neurodegeneration and Fetal Alcohol Syndrome
2000 StandoutScience
Cell-based assays and instrumentation for screening ion-channel targets
1999
Ro 25–6981, a Highly Potent and Selective Blocker of N-Methyl-d-aspartate Receptors Containing the NR2B Subunit. Characterization in Vitro
1997
Activation of Group I mGluRs Is Necessary for Induction of Long-Term Depression at Striatal Synapses
2001
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins
2002 StandoutNobel
Essential Role of thefosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures
1998
Effector Cell-Derived Lymphotoxin α and Fas Ligand, but not Perforin, Promote Tc1 and Tc2 Effector Cell-Mediated Tumor Therapy in Established Pulmonary Metastases
2004
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
The Glutamate Receptor Ion Channels
1999 Standout
Artificial Molecular Machines
2015 Standout
Copper-free palladium-catalyzed sonogashira-type coupling of aryl halides and 1-aryl-2-(trimethylsilyl)acetylenes
2005
12-Lipoxygenase Metabolites of Arachidonic Acid Mediate Metabotropic Glutamate Receptor-Dependent Long-Term Depression at Hippocampal CA3-CA1 Synapses
2003
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
CCR4 as a Therapeutic Target for Cancer Immunotherapy
2021
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Human dendritic cell subsets in NOD/SCID mice engrafted with CD34+ hematopoietic progenitors
2003
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
The glutamate receptor ion channels.
1999
Activation of Microglial Group III Metabotropic Glutamate Receptors Protects Neurons against Microglial Neurotoxicity
2003
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Photo-controlled deactivation of immobilised lipase
2014 StandoutNobel
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]- pyridine: A Potent and Highly Selective Metabotropic Glutamate Subtype 5 Receptor Antagonist with Anxiolytic Activity
2002
Rufinamide Attenuates Mechanical Allodynia in a Model of Neuropathic Pain in the Mouse and Stabilizes Voltage-gated Sodium Channel Inactivated State
2012
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
2011 StandoutNobel
Synthesis and Structure−Activity Relationships of 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Analogues as Potent, Noncompetitive Metabotropic Glutamate Receptor Subtype 5 Antagonists; Search for Cocaine Medications
2006
Quinazolin-4-one Derivatives: A Novel Class of Noncompetitive NR2C/D Subunit-SelectiveN-Methyl-d -aspartate Receptor Antagonists
2010
PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORS
1997 Standout
Design, Synthesis, and Structure−Activity Relationships of Novel Bicyclic Azole-amines as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 5
2010
Physiology of Microglia
2011 Standout
Image processing with ImageJ
2004 Standout
Oxygen Transport and Hemocyanin Function in the Pulmonate Land Snail,Helix pomatia:Physiological and Molecular Implications of Polyphasic Oxygen-binding Curves
1992
Works of Stephen D. Hess being referenced
[2] Fluorescence techniques for measuring ion channel activity
1999
Stable expression and characterization of recombinant human heteromeric N-methyl-D-aspartate receptor subtypes NMDAR1A/2A and NMDAR1A/2B in mammalian cells.
1996
(R, S)-4-Phosphonophenylglycine, a Potent and Selective Group III Metabotropic Glutamate Receptor Agonist, Is Anticonvulsive and Neuroprotective In Vivo
1999
Pharmacological Characterization of the Human Ionotropic Glutamate Receptor Subtype GluR3 Stably Expressed in Mammalian Cells
1998
Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5
1995
Immunopathogenesis and therapy of cutaneous T cell lymphoma
2005
Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma
2009
Human–SCID mouse chimeric models for the evaluation of anti-cancer therapies
2001
Association of change in clinical status and change in the percentage of the CD4+CD26− lymphocyte population in patients with Sézary syndrome
2005
2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist
1999
The Human N‐Methyl‐d ‐Aspartate Receptor 2C Subunit: Genomic Analysis, Distribution in Human Brain, and Functional Expression
1998
Functional Characterization of Human N‐Methyl‐d ‐Aspartate Subtype 1A/2D Receptors
1998
Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-gamma-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice.
2002
202 Oxaliplatin: In vitro evidence of its radiation sensitizing activity — preclinical observations relevant to clinical trials
1999
Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors.
1996
Human CD4+ T Cells Present Within the Microenvironment of Human Lung Tumors Are Mobilized by the Local and Sustained Release of IL-12 to Kill Tumors In Situ by Indirect Effects of IFN-γ
2003
Physiological and Behavioural Aspects of Water Balance and Respiratory Function in the Terrestrial Slug, Limax Maximus
1983
SIB-1757 and SIB-1893: Selective, Noncompetitive Antagonists of Metabotropic Glutamate Receptor Type 5
1999