Stephen Claridge

Epigenetics and the environment: emerging patterns and implications

Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection

A chemical probe toolbox for dissecting the cancer epigenome

Catalytic Functionalization of Indoles in a New Dimension

Animal Models to Study Environmental Epigenetics1

A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

Monofluorination of Organic Compounds: 10 Years of Innovation

Protected propargylic acetals. Nicholas–Prins cyclization leading to functionalized 2-alkynyl-tetrahydropyrans. Intramolecular trapping by allenes

Stereochemical Control in Organic Synthesis Using Silicon-Containing Compounds

Synthesis and Evaluation of Analogues of N-Phthaloyl-l-tryptophan (RG108) as Inhibitors of DNA Methyltransferase 1

Anodic oxidation of chiral sulfinylamines: a new route to highly diastereoselective α-alkylation of piperidine

Carbon−Carbon Bond Forming Reactions Mediated by Silicon Lewis Acids

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

A concise total synthesis of puberulic acid, a potent antimalarial agent

Synthesis of a novel Boc-protected cyclopropane-modified proline analogue

Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

The Nicholas reaction: the use of dicobalt hexacarbonyl-stabilised propargylic cations in synthesis

Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance

A study into asymmetric Nicholas cyclisation reactions

Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids

The Enterprise of Synthesis: From Concept to Practice

Gold-Catalyzed Carbon−Heteroatom Bond-Forming Reactions

First Direct Reductive Amination of Mucochloric Acid:  A Simple and Efficient Method for Preparing Highly Functionalized α,β-Unsaturated γ-Butyrolactams

Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions

A Novel Metal Iodide Promoted Three-Component Synthesis of Substituted Pyrrolidines

Stronger Brønsted Acids

Iodine-catalyzed C- and O-nucleophilic substitution reactions of aryl-propargyl methanols

Probing the importance of spacial and conformational domains in captopril analogs for angiotensin converting enzyme activity

Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors

SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes

The Power of Visual Imagery in Synthesis Planning. Stereocontrolled Approaches to CGP-60536B, a Potent Renin Inhibitor

The Nicholas Reaction: 2. An Intramolecular Approach to the Synthesis of Fused Carbocycles

ChemInform Abstract: The Nicholas Reaction. Part 2. An Intramolecular Approach to the Synthesis of Fused Carbocycles.

A diastereoselective synthesis of benzopyrans using a novel intramolecular Nicholas reaction in the key cyclisation step