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Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Predominant Autoantibody Production by Early Human B Cell Precursors
2003 StandoutScience
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Structure of the Quaternary Complex of Interleukin-2 with Its α, ß, and γ c Receptors
2005 Science
Role of CXCR5 and CCR7 in Follicular Th Cell Positioning and Appearance of a Programmed Cell Death Gene-1High Germinal Center-Associated Subpopulation
2007
Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
1994 Nature
Positive and negative selection events during B lymphopoiesis
1995
Protein tyrosine kinase syk is associated with and activated by the il-2 receptor: Possible link with the c-myc induction pathway
1995
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
1989 Nature
Origin of Murine B Cell Lineages
1993
Marginal-zone B cells
2002
Control of B-cell responses by Toll-like receptors
2005 Nature
Differential activation of transcription factors induced by Ca2+ response amplitude and duration
1997 Nature
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor
1995
Regulatory T Cells
2000 StandoutNobel
Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways
1989
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Different Nuclear Signals Are Activated by the B Cell Receptor during Positive Versus Negative Signaling
1997
Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation
1995
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps
2015
Transfusion Medicine — Blood Transfusion
1999 Standout
Positive Selection from Newly Formed to Marginal Zone B Cells Depends on the Rate of Clonal Production, CD19, and btk
2000
Celiac Disease
2007 Standout
Follicular B helper T cells in antibody responses and autoimmunity
2005
Immature B cells from human and mouse bone marrow can change their surface light chain expression
1995
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
1991 Nature
CD4: Collaborator in immune recognition and HIV infection
1990 StandoutNobel
Dimerization of cell surface receptors in signal transduction
1995
Signaling thresholds and interclonal competition in preimmune B‐cell selection
1997
T Cell–Mediated Elimination of B7.2 Transgenic B Cells
1997 StandoutNobel
CD21highIgMhigh Splenic B Cells Enriched in the Marginal Zone: Distinct Phenotypes and Functions
1999
Expansion or Elimination of B Cells In Vivo: Dual Roles for CD40- and Fas (CD95)-Ligands Modulated by the B Cell Antigen Receptor
1996
Toll-like receptors: balancing host resistance with immune tolerance
2003
Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
1995
Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process
1995
Acquisition of immunologic self-tolerance
1989
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
Peripheral deletion of self-reactive B cells
1991 Nature
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Defective lymphoid development in mice lacking expression of the common cytokine receptor γ chain
1995
Self-Tolerance Checkpoints in B Lymphocyte Development
1995
Induction of self-tolerance in mature peripheral B lymphocytes
1989 Nature
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Clonal selection and learning in the antibody system
1996 StandoutNature
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Abnormal B lymphocyte delevopment, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
1995
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice
1994 StandoutNobel
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells
1995 Nature
The role of shared receptor motifs and common stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15
1995
Cellular and Molecular Mechanisms of B Lymphocyte Tolerance
1992
Transgenic Mice and Analysis of B-Cell Tolerance
1992
B‐cell CD25 Expression in Murine Primary and Secondary Lymphoid Tissue
2006
Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
1993
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
1991 Nature
The site and stage of anti-DNA B-cell deletion
1995 Nature
The Molecular Basis of X‐Linked Severe Combined Immunodeficiency: The Role of the Interleukin‐2 Receptor γ Chain as a Common γ Chain, γc
1994
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease
2000
Aire regulates negative selection of organ-specific T cells
2003
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Contribution of the Box 1 and Box 2 Motifs of Cytokine Receptors to Jak1 Association and Activation
2002
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
2009 Standout
Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells
1989 Nature
Virus-specific CD8+ T-cell memory determined by clonal burst size
1994 StandoutNatureNobel
Immunological Memory
1993
The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow.
1993 StandoutNobel
Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor
1993 Science
Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4+ T Cells
1998 StandoutNobel
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus.
1995
A transgenic model of autoimmune hemolytic anemia.
1992 StandoutNobel
DNA Variability and Recombination Rates at X-Linked Loci in Humans
1998
A Nondeletional Mechanism of Thymic Self Tolerance
1989 StandoutScienceNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Induction of classical transplantation tolerance in the adult.
1989
C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity
1996 Science
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off
1998 Science
Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.
1994
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation.
1994
Cross-linking of membrane immunoglobulin D, in the absence of T cell help, kills mature B cells in vivo.
1995
RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.
1993
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus
2001 StandoutNobel
Extensive Nuclear DNA Sequence Diversity Among Chimpanzees
1999 StandoutScienceNobel
Biologic effects of leukocytes present in transfused cellular blood products
1994
Contribution of Receptor Editing to the Antibody Repertoire
2001 Science
Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein
1997
Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment
1999 StandoutNobel
The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.
1996
B cells acquire antigen from target cells after synapse formation
2001 Nature
B lymphocytes may escape tolerance by revising their antigen receptors.
1993
Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes.
1994
Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.
1994 StandoutNobel
Interaction of IL-2Rβ and γ c Chains with Jak1 and Jak3: Implications for XSCID and XCID
1994 Science
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Assessing the quality of reports of randomised trials: implications for the conduct of meta-analyses.
1999
Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.
1994
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
Functional Activation of Jak1 and Jak3 by Selective Association with IL-2 Receptor Subunits
1994 Science
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Seppuku and Autoimmunity
1992 StandoutScienceNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
T Cell Accumulation in B Cell Follicles Is Regulated by Dendritic Cells and Is Independent of B Cell Activation
2003
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions.
1994
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Prevention of Scrapie Pathogenesis by Transgenic Expression of Anti-Prion Protein Antibodies
2001 Science
Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission.
1995
Somatic Hypermutation in the Absence of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-Pkcs) or Recombination-Activating Gene (Rag)1 Activity
2000
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Tolerant B Lymphocytes Acquire Resistance to Fas-mediated Apoptosis after Treatment with Interleukin 4 but Not after Treatment with Specific Antigen Unless a Surface Immunoglobulin Threshold Is Exceeded
1998
Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 Receptor
1993 Science
Inducible Costimulator Protein (Icos) Controls T Helper Cell Subset Polarization after Virus and Parasite Infection
2000
Human anti-self antibodies with high specificity from phage display libraries.
1993
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Works of Stephen Adelstein being referenced
Treatment of Recurrent Spontaneous Abortion by Immunization With Paternal Lymphocytes: Results of a Controlled Trial
1993
Clonal Silencing of Self-reactive B Lymphocytes in a Transgenic Mouse Model
1989
Suppressor T-Cell Memory
1990
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
1988 Nature
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells
2005
A comparison of 13 guinea pig and human anti-tissue transglutaminase antibody ELISA kits
2002
Heterodimerization of the IL-2 receptor β- and γ-chain cytoplasmic domains is required for signalling
1994 Nature
Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells
2005
Characterization of the human interleukin-2 receptor gamma chain gene
1993
Induction of Self-Rolerance in T Cells But Not B Cells of Transgenic Mice Expressing Little Self Antigen
1991 Science
The Need for Central and Peripheral Tolerance in the B Cell Repertoire
1990 Science