Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
2010 Standout
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Realizing private and practical pharmacological collaboration
2018 Science
An EGFR/Ebi/Sno Pathway Promotes Delta Expression by Inactivating Su(H)/SMRTER Repression during Inductive Notch Signaling
2002
Deletion of the Src Homology 3 Domain and C-terminal Proline-rich Sequences in Bcr-Abl Prevents Abl Interactor 2 Degradation and Spontaneous Cell Migration and Impairs Leukemogenesis
2001
Imaging beyond the proteome
2012 StandoutNobel
Molecular imaging in living subjects: seeing fundamental biological processes in a new light
2003 Standout
A novel mammalian endoplasmic reticulum ubiquitin ligase homologous to the yeast Hrd1
2003 StandoutNobel
Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth
2014
Hematologic and Cytogenetic Responses to Imatinib Mesylate in Chronic Myelogenous Leukemia
2002 Standout
Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes
2011
Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level
2006
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Ras-Activated Endocytosis Is Mediated by the Rab5 Guanine Nucleotide Exchange Activity of RIN1
2001
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia
2001 Standout
Bcr–Abl variants: biological and clinical aspects
2002
Oncomine 3.0: Genes, Pathways, and Networks in a Collection of 18,000 Cancer Gene Expression Profiles
2007 Standout
Dasatinib in Imatinib-Resistant Philadelphia Chromosome–Positive Leukemias
2006 Standout
Array-based genomic resequencing of human leukemia
2010
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations
2009
Cytokine-dependent imatinib resistance in mouse BCR-ABL+, Arf-null lymphoblastic leukemia
2007
Rab GTPases as coordinators of vesicle traffic
2009 Standout
The landscape of long noncoding RNAs in the human transcriptome
2015 Standout
Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
2008 Standout
Conservation, Variability and the Modeling of Active Protein Kinases
2007 StandoutNobel
High-performance medicine: the convergence of human and artificial intelligence
2018 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation
2005 StandoutNobel
Notch signalling: a simple pathway becomes complex
2006 Standout
Cancer driver mutations in protein kinase genes
2008
Clonal evolution with inv(11)(p15q22) and NUP98/DDX10 fusion gene in imatinib-resistant chronic myelogenous leukemia
2005
Targeting RAS signalling pathways in cancer therapy
2003 Standout
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Stems Cells and the Pathways to Aging and Cancer
2008
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions
2011 Standout
Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome
2001 Standout
Chemistry in living systems
2005 StandoutNobel
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
The cancer stem cell: premises, promises and challenges
2011 Standout
Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells
2008
Structure, Exchange Determinants, and Family-Wide Rab Specificity of the Tandem Helical Bundle and Vps9 Domains of Rabex-5
2004
Increasing Complexity of the Ras Signaling Pathway
1998
The Hallmarks of Aging
2013 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
The PI3K Pathway in Human Disease
2017 Standout
Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido
2011 StandoutNobel
Chronic Myeloid Leukemia
1999
MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors
2004
FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes
2006
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Targeted CML therapy: controlling drug resistance, seeking cure
2005
Small GTP-Binding Proteins
2001 Standout
Programmed death 1 signaling on chronic myeloid leukemia–specific T cells results in T-cell exhaustion and disease progression
2009
A Strategy for the Selective Imaging of Glycans Using Caged Metabolic Precursors
2010 StandoutNobel
Differential regulation of the p70 S6 kinase pathway by interferon α (IFNα) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells
2005
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
2013 Standout
Transforming property of TEL-FGFR3 mediated through PI3-K in a T-cell lymphoma that subsequently progressed to AML
2004
Concepts in Ras-directed therapy
1999
The role of DNA breaks in genomic instability and tumorigenesis
2003
Imaging Tri-Fusion Multimodality Reporter Gene Expression in Living Subjects
2004 StandoutNobel
Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
2000 StandoutScience
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters
2007 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
2003
A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis
2020 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
HIF1α is required for survival maintenance of chronic myeloid leukemia stem cells
2012
De novo design of protein logic gates
2020 StandoutScienceNobel
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
Inorganic Nanoparticles for MRI Contrast Agents
2009 Standout
Construction and Validation of Improved Triple Fusion Reporter Gene Vectors for Molecular Imaging of Living Subjects
2007 StandoutNobel
Works of Stephane Wong being referenced
Phosphoinositide 3-kinase signaling is essential for ABL oncogene–mediated transformation of B-lineage cells
2004
Regulation of the Oncogenic Activity of BCR-ABL by a Tightly Bound Substrate Protein RIN1
1997
Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene
2002
Modeling Philadelphia chromosome positive leukemias
2001
The BCR-ABL Story: Bench to Bedside and Back
2004
BCR/ABL inhibition by an escort/phosphatase fusion protein
2000
Cell context–specific effects of the BCR-ABL oncogene monitored in hematopoietic progenitors
2003