Citation Impact
Citing Papers
Cellular Restriction Targeting Viral Capsids Perturbs Human Immunodeficiency Virus Type 1 Infection of Nondividing Cells
2009
Suppression of Oxidative Stress by β-Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
2012 Science
Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA
2008
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
Regulation of alternative splicing by a transcriptional enhancer through RNA pol II elongation
2002 StandoutNobel
Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
2013 StandoutNobel
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines.
2003
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness
2000
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Role of Caspases, Bid, and p53 in the Apoptotic Response Triggered by Histone Deacetylase Inhibitors Trichostatin-A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA)
2003
An evolutionarily conserved transcriptional response to viral infection in Caenorhabditis nematodes
2017
Activation of p53 Sequence-Specific DNA Binding by Acetylation of the p53 C-Terminal Domain
1997 Standout
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
HIV DNA Integration
2012
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency
2011
Differential Display Cloning of a Novel Human Histone Deacetylase (HDAC3) cDNA from PHA-Activated Immune Cells
1998
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta
2003
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
2001
What's Up and Down with Histone Deacetylation and Transcription?
1997
E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation
2006
Shaping the nuclear action of NF-κB
2004
SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex
1998
A Cas9 Ribonucleoprotein Platform for Functional Genetic Studies of HIV-Host Interactions in Primary Human T Cells
2016 StandoutNobel
Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1
2001
Class II histone deacetylases: versatile regulators
2003
Histone-deacetylase inhibitors: novel drugs for the treatment of cancer
2002
FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing
2019 Nature
Histone deacetylation in epigenetics: An attractive target for anticancer therapy
2005
Acetylation of TAFI68, a subunit of TIF-IB/SL1, activates RNA polymerase I transcription
2001
Molecular Evolution of the Histone Deacetylase Family: Functional Implications of Phylogenetic Analysis
2004
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Active Repression of Antiapoptotic Gene Expression by RelA(p65) NF-κB
2004
Acetylation and deacetylation of non-histone proteins
2005
Enzymatic Activity Associated with Class II HDACs Is Dependent on a Multiprotein Complex Containing HDAC3 and SMRT/N-CoR
2002
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Histone deacetylases and cancer: causes and therapies
2001 Standout
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Canine Hepacivirus NS3 Serine Protease Can Cleave the Human Adaptor Proteins MAVS and TRIF
2012
Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5
2000 StandoutNobel
Trichostatin A Modulates Expression of p21waf1/cip1, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in Human Lung Adenocarcinoma Cells
2000
Krüppel-like Factor 4 Is Acetylated by p300 and Regulates Gene Transcription via Modulation of Histone Acetylation
2007
The Metastasis-associated Proteins 1 and 2 Form Distinct Protein Complexes with Histone Deacetylase Activity
2003
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Nuclear import by karyopherin-βs: Recognition and inhibition
2010
Acetylation: a regulatory modification to rival phosphorylation?
2000
Evidence for IFNα-induced, SAMHD1-independent inhibitors of early HIV-1 infection
2013
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
LEDGF/p75 interacts with divergent lentiviral integrases and modulates their enzymatic activity in vitro
2006
The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase
2003
TNPO3 protects HIV-1 replication from CPSF6-mediated capsid stabilization in the host cell cytoplasm
2013
Oncogenic aberrations of cullin-dependent ubiquitin ligases
2004
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
Signaling to NF-κB
2004 Standout
Histone acetylation in chromatin structure and transcription
1997 StandoutNature
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors
1999 Nature
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
2001 Standout
Histone Deacetylases Associated with the mSin3 Corepressor Mediate Mad Transcriptional Repression
1997
A Novel Co-Crystal Structure Affords the Design of Gain-of-Function Lentiviral Integrase Mutants in the Presence of Modified PSIP1/LEDGF/p75
2009
Histone deacetylase inhibitors in clinical development
2004
Knockdown Screens to Knockout HIV-1
2008
Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer
2006 Standout
Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase
2004 Standout
The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities
1998
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Dynamics of histone acetylation in vivo. A function for acetylation turnover?
2002
Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3
2000
Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
2015
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Negative regulation of activation-induced cytidine deaminase in B cells
2006 StandoutNobel
Three proteins define a class of human histone deacetylases related to yeast Hda1p
1999
The Immunoglobulin Heavy Chain Locus Control Region Increases Histone Acetylation along Linked c-myc Genes
1998
Cell cycle-dependent regulation of the Skp2 promoter by GA-binding protein.
2003
Human Immunodeficiency Virus Induces a Dual Regulation of Bcl-2, Resulting in Persistent Infection of CD4+T- or Monocytic Cell Lines
1998 StandoutNobel
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
2003
The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1.
2003
Differential Effects of Human Immunodeficiency Virus Type 1 Capsid and Cellular Factors Nucleoporin 153 and LEDGF/p75 on the Efficiency and Specificity of Viral DNA Integration
2012
CBP/p300 in cell growth, transformation, and development
2000
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Histone Deacetylase Inhibitors Trigger a G2 Checkpoint in Normal Cells That Is Defective in Tumor Cells
2000
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Deacetylase Activity Is Required for Recruitment of the Basal Transcription Machinery and Transactivation by STAT5
2003
Subtype Selective Substrates for Histone Deacetylases
2004
Histone deacetylase (HDAC) inhibitor activation of p21 WAF1 involves changes in promoter-associated proteins, including HDAC1
2004
Phase I and Pharmacokinetic Study of MS-275, a Histone Deacetylase Inhibitor, in Patients With Advanced and Refractory Solid Tumors or Lymphoma
2005
Adaptation to the Interferon-Induced Antiviral State by Human and Simian Immunodeficiency Viruses
2013
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
The Biology of Chromatin Remodeling Complexes
2009 Standout
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Hypoxia induces macrophage inflammatory protein‐2 (MIP‐2) gene expression in murine macrophages via NF‐κB: the prominent role of p42/ p44 and PI3 kinase pathways
2004
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
2000
Histone Deacetylase Inhibitors
2003
TRANSCRIPTION OF EUKARYOTIC PROTEIN-CODING GENES
2000
Towards an HIV cure: a global scientific strategy
2012
The transcriptional cycle of HIV-1 in real-time and live cells
2007
T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance
2004
Increased Transcription Levels Induce Higher Mutation Rates in a Hypermutating Cell Line
2001
DNA cleavage in immunoglobulin somatic hypermutation depends onde novoprotein synthesis but not on uracil DNA glycosylase
2005 StandoutNobel
Histone Acetylation Determines the Developmentally Regulated Accessibility for T Cell Receptor γ Gene Recombination
2001 StandoutNobel
Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer
2005
Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of Their Replication Capacity in CD4 T Lymphocytes and Monocyte-Derived Macrophages
2011
Use and Abuse of RNAi to Study Mammalian Gene Function
2012 StandoutScienceNobel
Phase I clinical trial of histone deacetylase inhibitor: suberoylanilide hydroxamic acid administered intravenously.
2003
Syntheses of Thailandepsin B Pseudo‐Natural Products: Access to New Highly Potent HDAC Inhibitors via Late‐Stage Modification
2020
Multiple N-CoR Complexes Contain Distinct Histone Deacetylases
2001
Variable deletion and duplication at recombination junction ends: Implication for staggered double-strand cleavage in class-switch recombination
2001 StandoutNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
2005
Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms.
2002
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia
2001
Association of the Mediator complex with enhancers of active genes
2003 StandoutNobel
RBP1 Recruits the mSIN3-Histone Deacetylase Complex to the Pocket of Retinoblastoma Tumor Suppressor Family Proteins Found in Limited Discrete Regions of the Nucleus at Growth Arrest
2001
Metabolic labeling enables selective photocrosslinking of O-GlcNAc-modified proteins to their binding partners
2012 StandoutNobel
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
1999 StandoutNobel
Histone deacetylase inhibitor selectively induces p21 WAF1 expression and gene-associated histone acetylation
2000
CLINICAL DEVELOPMENT OF HISTONE DEACETYLASE INHIBITORS AS ANTICANCER AGENTS
2004
Works of Stéphane Emiliani being referenced
Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65
2003
Integrase Mutants Defective for Interaction with LEDGF/p75 Are Impairedin Chromosome Tethering and HIV-1Replication
2005
Mutations affecting interaction of integrase with TNPO3 do not prevent HIV-1 cDNA nuclear import
2011
Requirement for SWI/SNF chromatin‐remodeling complex in Tat‐mediated activation of the HIV‐1 promoter
2006
A non-proteolytic role for ubiquitin in Tat-mediated transactivation of the HIV-1 promoter
2003
Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity
1999
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
2011 Nature
Suv39H1 and HP1γ are responsible for chromatin‐mediated HIV‐1 transcriptional silencing and post‐integration latency
2007
Transportin-SR2 Imports HIV into the Nucleus
2008
The Integrase Cofactor LEDGF/p75 Associates with Iws1 and Spt6 for Postintegration Silencing of HIV-1 Gene Expression in Latently Infected Cells
2015
A New Family of Human Histone Deacetylases Related toSaccharomyces cerevisiae HDA1p
1999
Inhibition of Early Steps of HIV-1 Replication by SNF5/Ini1
2006
The Interaction of LEDGF/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding
2005
Clonal analysis of murine b cell response to the human immunodeficiency virus type 1 (HIV1)-gag p17 and p25 antigens
1992
Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.
1996
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
1998
Characterization of a human RPD3 ortholog, HDAC3
1998
Interaction between Cyclin T1 and SCFSKP2 Targets CDK9 for Ubiquitination and Degradation by the Proteasome
2001
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.
1996