Standout Papers
Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
RNA-Guided Human Genome Engineering via Cas9
2013 StandoutScience
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
2002 Standout
Term-seq reveals abundant ribo-regulation of antibiotics resistance in bacteria
2016 Science
Laboratory evolution of virus-like nucleocapsids from nonviral protein cages
2018
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
2015 StandoutNatureNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability
2013 Standout
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28
2017
A new frontier for molecular medicine: Noncoding RNAs
2005
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
MicroRNAs
2004 Standout
TBtools: An Integrative Toolkit Developed for Interactive Analyses of Big Biological Data
2020 Standout
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Efficient use of accessibility in microRNA target prediction
2010
The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
2013 StandoutNobel
PicXAA-R: Efficient structural alignment of multiple RNA sequences using a greedy approach
2011
CRISPR interference (CRISPRi) for sequence-specific control of gene expression
2013
Experimental validation of the regulated expression of large numbers of non-coding RNAs from the mouse genome
2005
Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III inStreptococcus pyogenes
2017 StandoutNobel
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
RNA targeting with CRISPR–Cas13
2017 Nature
An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3′-to-5′ exoRNases and RNase Y
2020 StandoutNobel
Cas13d Is a Compact RNA-Targeting Type VI CRISPR Effector Positively Modulated by a WYL-Domain-Containing Accessory Protein
2018
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules
2016 Standout
LocARNA-P: Accurate boundary prediction and improved detection of structural RNAs
2012
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Deletion analysis of chromosome 13q14.3 and characterisation of an alternative splice form of LEU1 in B cell chronic lymphocytic leukemia
2002
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Comprehensive analysis of a large genomic sequence at the putative B-cell chronic lymphocytic leukaemia (B-CLL) tumour suppresser gene locus
2001
Secondary Structure across the Bacterial Transcriptome Reveals Versatile Roles in mRNA Regulation and Function
2015
Rapid evolution of noncoding RNAs: lack of conservation does not mean lack of function
2005
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
2016 StandoutNatureNobel
Dynamical features of thePlasmodium falciparumribosome during translation
2015 StandoutNobel
MicroRNA Pathways in Flies and Worms
2003 StandoutNobel
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Characterization of the CRISPR/Cas Subtype I-A System of the Hyperthermophilic Crenarchaeon Thermoproteus tenax
2012
The role of site accessibility in microRNA target recognition
2007 Standout
Chromosome aberrations in B-cell chronic lymphocytic leukemia: reassessment based on molecular cytogenetic analysis
1999
CRISPRmap: an automated classification of repeat conservation in prokaryotic adaptive immune systems
2013
psRNATarget: a plant small RNA target analysis server
2011 Standout
RNA sequencing uncovers antisense RNAs and novel small RNAs inStreptococcus pyogenes
2015 StandoutNobel
Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia
2000 Standout
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases
2016
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
The HDOCK server for integrated protein–protein docking
2020
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
A fast structural multiple alignment method for long RNA sequences
2008
Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene.
2001
Serology-Enabled Discovery of Genetically Diverse Hepaciviruses in a New Host
2012 StandoutNobel
A prudent path forward for genomic engineering and germline gene modification
2015 StandoutScienceNobel
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia
2001
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
IntaRNA: efficient prediction of bacterial sRNA targets incorporating target site accessibility and seed regions
2008
Complementary Sequence-Mediated Exon Circularization
2014 Standout
mRNA secondary structure optimization using a correlated stem–loop prediction
2013
Super-Resolution in Solution X-Ray Scattering and Its Applications to Structural Systems Biology
2013
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Identification of a Pegivirus (GB Virus-Like Virus) That Infects Horses
2013 StandoutNobel
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Rewriting a genome
2013 StandoutNatureNobel
Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation
2016
t(11;14)-positive mantle cell lymphomas exhibit complex karyotypes and share similarities with B-cell chronic lymphocytic leukemia
2000
Works of Stephan Wolf being referenced
RNAalifold: improved consensus structure prediction for RNA alignments
2008
Invertebrate 7SK snRNAs
2008
Partition function and base pairing probabilities of RNA heterodimers
2006
Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing
2010
B-cell neoplasia associated gene with multiple splicing (BCMS): the candidate B-CLL gene on 13q14 comprises more than 560 kb covering all critical regions
2001
ViennaRNA Package 2.0
2011 Standout
Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma
1998
Strategies for measuring evolutionary conservation of RNA secondary structures
2008
The Vienna RNA Websuite
2008 Standout
Variations on RNA folding and alignment: lessons from Benasque
2007
BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31,BCMSUN-like
2000
Alignment of RNA base pairing probability matrices
2004
Local RNA base pairing probabilities in large sequences
2005
Thermodynamics of RNA–RNA binding
2006
Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia
2002