Standout Papers
Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
DiffVar: a new method for detecting differential variability with application to methylation in cancer and aging
2014
Differential Antigen Processing by Dendritic Cell Subsets in Vivo
2007 StandoutScienceNobel
Recognition of a virus-encoded ligand by a natural killer cell activation receptor
2002
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Distinct prion proteins in short and long scrapie incubation period mice
1987 StandoutNobel
Ferrocene-oligonucleotide conjugates for electrochemical probing of DNA
1996
Strategies for dissecting epigenetic mechanisms in the mouse
2005
Crystal structure and mutational analysis of human uracil-DNA glycosylase: Structural basis for specificity and catalysis
1995
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
2005
Cancer Immunosurveillance and Immunoediting: The Roles of Immunity in Suppressing Tumor Development and Shaping Tumor Immunogenicity
2006
Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA
1998
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
Charting a dynamic DNA methylation landscape of the human genome
2013 Nature
The nature of the MHC class I peptide loading complex
1999
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Maternal methyl supplements increase offspring DNA methylation at Axin fused
2006
The functional repertoires of metazoan genomes
2008
Genetic Differences between Humans and Great Apes
2001
A Spatial Map of Olfactory Receptor Expression in the Drosophila Antenna
1999 StandoutNobel
Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex
2001
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Genome-wide High-Resolution Mapping and Functional Analysis of DNA Methylation in Arabidopsis
2006
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
2005
Highly parallel genomic assays
2006
Gene Switching and the Stability of Odorant Receptor Gene Choice
2004 StandoutNobel
Short-Insert Libraries as a Method of Problem Solving in Genome Sequencing
1998 StandoutNobel
Sources of diversity in T cell epitope discovery
2011
Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
1996 StandoutNature
The Mammalian Epigenome
2007 Standout
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
CRISPR/Cas9-Based Engineering of the Epigenome
2017
Modulation of MHC antigen expression by viruses and oncogenes
1991
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Genes Induced in Programmed Cell Death of Neuronal PC12 Cells and Developing Sympathetic Neuronsin Vivo
1997
Dynamics of DNA Methylation in Recent Human and Great Ape Evolution
2013
Two Large Families of Chemoreceptor Genes in the NematodesCaenorhabditis elegans and Caenorhabditis briggsae Reveal Extensive Gene Duplication, Diversification, Movement, and Intron Loss
1998
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
1993
Solution structure of the second bromodomain of Brd2 and its specific interaction with acetylated histone tails
2007
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Epigenomics: beyond CpG islands
2004
Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing
2013
The mosaic that is our genome
2003 StandoutNatureNobel
Tumour hypoxia causes DNA hypermethylation by reducing TET activity
2016 Nature
Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, “minor” D segments or D-D recombination 1 1Edited By J. Karn
1997 StandoutNobel
A sequence assembly and editing program for efficient management of large projects
1991
Hypoxia-induced epigenetic modifications are associated with cardiac tissue fibrosis and the development of a myofibroblast-like phenotype
2013
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Identification and Characterization of BRDT: A Testis-Specific Gene Related to the Bromodomain Genes RING3 andDrosophila fsh
1997
CpG Island Methylation in Human Lymphocytes Is Highly Correlated with DNA Sequence, Repeats, and Predicted DNA Structure
2006
Fluorescent dye-primer cycle sequencing using unpurified PCR products as templates; development of a protocol amenable to high-throughput DNA sequencing
1995
Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic Resolution
2009
Cancer epigenomics: DNA methylomes and histone-modification maps
2007 Standout
Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3
2005
The B7–CD28 superfamily
2002
Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2
1994 StandoutNatureNobel
The sense of smell: genomics of vertebrate odorant receptors
2002
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)
1996 Standout
Bioorganometallic Chemistry of Ferrocene
2004 Standout
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels
2003
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
1988 StandoutScienceNobel
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation.
1993
Interpreting patterns of gene expression with self-organizing maps: Methods and application to hematopoietic differentiation
1999 Standout
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation.
1996 StandoutNobel
Requirement of Mip-1α for an Inflammatory Response to Viral Infection
1995 StandoutScienceNobel
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus)
1996 StandoutNobel
A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator.
1996
Intra- and Interspecific Variation in Primate Gene Expression Patterns
2002 StandoutScienceNobel
Conserved Structures of Mediator and RNA Polymerase II Holoenzyme
1999 StandoutScienceNobel
Translocation events in the evolution of aminoacyl-tRNA synthetases.
1996 StandoutNobel
Linear amplification sequencing, a powerful method for sequencing DNA
1991
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Statistics of local complexity in amino acid sequences and sequence databases
1993
Identification of an evolutionarily conserved 110 base-pair cis-acting regulatory sequence that governs Wnt-1 expression in the murine neural plate
1998 StandoutNobel
Large-Scale and Automated DNA Sequence Determination
1991 Science
Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains
1995
The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses
2002
Primary structure of the herpesvirus saimiri genome
1992
The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL
1996
Identification of Transcription Complexes that Contain the Double Bromodomain Protein Brd2 and Chromatin Remodeling Machines
2006
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Regulation Mechanism of Spin−Orbit Coupling in Charge-Transfer-Induced Luminescence of Imidazopyrazinone Derivatives
2007
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
2007 StandoutNobel
Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes
1986 StandoutNatureNobel
Effects of interferon treatment on the antiviral T-cell response in hepatitis C virus genotype 1b- and genotype 2c-infected patients
1997 StandoutNobel
Unfinished symphony
2006 Nature
A Blueprint for a Human Epigenome Project: The AACR Human Epigenome Workshop
2005
Rapid transfer of DNA from agarose gels to nylon membranes
1985 Standout
The Human Genome Project: Reaching the Finish Line
1998 StandoutScienceNobel
Tetracycline repressor-regulated gene repression in recombinant human cytomegalovirus
1995
Works of Stephan Beck being referenced
Epigenomics: Genome-Wide Study of Methylation Phenomena
2002
Characterization of recombination in the HLA class II region.
1997
The DNA sequence of the human cytomegalovirus genome
1991
Polymorphisms in olfactory receptor genes: a cautionary note
2000
Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169
1990 Standout
The Cluster of BTN Genes in the Extended Major Histocompatibility Complex
2001
The genomic context of natural killer receptor extended gene families
2001
Complete sequence and gene map of a human major histocompatibility complex
1999 Nature
A Cluster of Ten Novel MHC Class I Related Genes on Human Chromosome 6q24.2–q25.3
2002
The human homologue of unc-93 maps to chromosome 6q27 – characterisation and analysis in sporadic epithelial ovarian cancer
2002
A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC
1992
BTL-II : a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse
2000
From genome to epigenome
2005
Germline rates of de novo meiotic deletions and duplications causing several genomic disorders
2007
Magnetic bead purification of M13 DNA sequencing templates
1992
Gene map of the extended humanMHC
2004
Epigenome-wide association studies for common human diseases
2011
Methylome analysis using MeDIP-seq with low DNA concentrations
2012
Identification and analysis of multigene families by comparison of exon fingerprints
1995
Human-specific CpG “beacons” identify loci associated with human-specific traits and disease
2012
A Strategy for the Amplification, Purification, and Selection of M13 Templates for Large-Scale DNA Sequencing
1993
DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing
1992
DNA Methylation-mediated Down-regulation of DNA Methyltransferase-1 (DNMT1) Is Coincident with, but Not Essential for, Global Hypomethylation in Human Placenta
2010
Genomic analysis of theTapasin gene, located close to theTAP loci in the MHC
1998
Automated DNA Hybridization
1994
Complex Transcription and Splicing of Odorant Receptor Genes
2003
Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene
1997
Applications of dioxetane chemiluminescent probes to molecular biology
1990
A complex between the MHC class I homologue encoded by human cytomegalovirus and β2 microglobulin
1990 Nature
DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project
2004
A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data
2012
ChAMP: 450k Chip Analysis Methylation Pipeline
2013
Isolation of Z-DNA-containing plasmids.
1983
Comparative sequence analysis of the human and pufferfish Huntington's disease genes
1995 StandoutNobel
DNA sequencing with direct blotting electrophoresis.
1984
[18] Direct transfer electrophoresis used for DNA sequencing
1987