Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Molecular and Cellular Aspects of Thiol–Disulfide Exchange
1990
Specific, irreversible inactivation of the epidermal growth factor receptor and erbB2, by a new class of tyrosine kinase inhibitor
1998
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Characterization of the oligosaccharide structures associated with the cystic fibrosis transmembrane conductance regulator
2000
mTOR Signaling in Growth Control and Disease
2012 Standout
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
2002 StandoutNature
Transmembrane TGF-α precursors activate EGF/TGF-α receptors
1989
The genetics of ageing
2010 StandoutNature
Epidermal growth factor—induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products
1993
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Signal transduction by receptors with tyrosine kinase activity
1990 Standout
ARF proteins mediate insulin-dependent activation of phospholipase D
1997
The Hallmarks of Cancer
2000 Standout
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Missing Pieces in the NF-κB Puzzle
2002 Standout
Diabetes epidemiology as a tool to trigger diabetes research and care
1999
Incidence and clinical characteristics of the metabolic syndrome in patients with coronary artery disease
2003
Global and societal implications of the diabetes epidemic
2001 StandoutNature
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
Phosphatidylcholine breakdown and signal transduction
1994
Cystic fibrosis: molecular biology and therapeutic implications
1992 StandoutScience
Epidermal growth factor activates calcium channels by phospholipase A25-lipoxygenase-mediated leukotriene C4 production
1992
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
2004 Nature
Leptin stimulates uncoupling protein‐2 mRNA expression and Krebs cycle activity and inhibits lipid synthesis in isolated rat white adipocytes
2000
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance
1991
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy
1993 StandoutNatureNobel
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Purification and properties of the human placental insulin receptor.
1981
The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins
1985 StandoutScienceNobel
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Protein Oxidation and Aging
1992 StandoutScience
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
1985 StandoutNature
The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptors.
1985
Regulation of adrenergic receptor function by phosphorylation. II. Effects of agonist occupancy on phosphorylation of alpha 1- and beta 2-adrenergic receptors by protein kinase C and the cyclic AMP-dependent protein kinase.
1987 StandoutNobel
Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. Affinity-purified insulin-like growth factor I receptor kinase is activated by tyrosine phosphorylation of its beta subunit.
1986
Nonenzymatic Covalent Posttranslational Modification of Proteins In Vivo
1985
Purification of the insulin receptor from human placenta by chromatography on immobilized wheat germ lectin and receptor antibody.
1980
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family
1985 StandoutNobel
All Autophosphorylation Sites of Epidermal Growth Factor (EGF) Receptor and HER2/neu Are Located in Their Carboxyl-terminal Tails
1989
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors
1981
Phorbol esters promote alpha 1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism.
1985 StandoutNobel
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
Insulin receptor: covalent labeling and identification of subunits.
1979
Phosphorylation of the mammalian beta-adrenergic receptor by cyclic AMP-dependent protein kinase. Regulation of the rate of receptor phosphorylation and dephosphorylation by agonist occupancy and effects on coupling of the receptor to the stimulatory guanine nucleotide regulatory protein.
1985 StandoutNobel
Epidermal growth factor binding induces a conformational change in the external domain of its receptor.
1989
The phytopathogenic bacteria Erwinia carotovora infects Drosophila and activates an immune response
2000 StandoutNobel
Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
1985 StandoutNobel
Common themes in microbial pathogenicity revisited.
1997
Mammalian beta-adrenergic receptors. Distinct glycoprotein populations containing high mannose or complex type carbohydrate chains.
1984 StandoutNobel
Photoaffinity labeling of the beta-adrenergic receptor.
1981 StandoutNobel
Malonyl-CoA, fuel sensing, and insulin resistance
1999
Purification of the major protein-tyrosine-phosphatases of human placenta.
1988 StandoutNobel
Common themes in microbial pathogenicity revisited
1997 Standout
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Endocytosis and the recycling of plasma membrane.
1983 StandoutNobel
Stable expression of truncated inositol 1,4,5-trisphosphate receptor subunits in 3T3 fibroblasts. Coordinate signaling changes and differential suppression of cell growth and transformation.
1994 StandoutNobel
Integrins and Signal Transduction Pathways: the Road Taken
1995 StandoutScience
Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85β protein by using the baculovirus expression system
1992
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product
1991 StandoutScience
Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo.
1986
Structure and expression of the human and mouse T4 genes.
1987 StandoutNobel
Tyrosine phosphorylation of the insulin receptor beta subunit activates the receptor-associated tyrosine kinase activity.
1984
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA
1984 StandoutNobel
Inhibition of Insulin Receptor Binding by Phorbol Esters
1982
Oxidized Redox State of Glutathione in the Endoplasmic Reticulum
1992 StandoutScience
Purification of the beta-adrenergic receptor. Identification of the hormone binding subunit.
1981 StandoutNobel
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains
1984 StandoutNatureNobel
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells.
1992
Tryptic activation of the insulin receptor. Proteolytic truncation of the alpha-subunit releases the beta-subunit from inhibitory control.
1988
How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein‐tyrosine kinase
1995
Works of Stella Clark being referenced
Loss of three major auto phosphorylation sites in the EGF receptor does not block the mitogenic action of EGF
1988
Leptin inhibits insulin binding in isolated rat adipocytes
1997
Nutrient-induced insulin resistance
1999
Expression of the human EGF receptor with ligand-stimulatable kinase activity in insect cells using a baculovirus vector.
1988
Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase
1991
Disulfide exchange between insulin and its receptor. A possible post-binding step in insulin action.
1983
Proteolytic generation of constitutive tyrosine kinase activity of the human insulin receptor
1989
The effects of trypsin and phospholipase C on insulin binding and action in the isolated adipocyte
1980
Modulation of phospholipase A2 activity by epidermal growth factor (EGF) in CHO cells transfected with human EGF receptor. Role of receptor cytoplasmic subdomain
1991
Salmonella typhimurium displays normal invasion of mice with defective epidermal growth factor receptors
1995
Increased flux through the hexosamine biosynthesis pathway inhibits glucose transport acutely by activation of protein kinase C
1997
Sulphydryl agents modulate insulin- and epidermal growth factor (EGF)-receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors
1993
Insulin and insulin-like growth factor-1 stimulate dephosphorylation of paxillin in parallel with focal adhesion kinase
1996
The Effect of Solubilization on the Properties of the Insulin Receptor of Human Placental Membranes*
1978