Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
A synthetic Escherichia coli predator–prey ecosystem
2008 StandoutNobel
Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA
2012 StandoutScience
Cell–cell signal-dependent dynamic interactions between HD-GYP and GGDEF domain proteins mediate virulence in Xanthomonas campestris
2010
A chemosensory system that regulates biofilm formation through modulation of cyclic diguanylate levels
2005
The Pseudomonas aeruginosa accessory genome elements influence virulence towards Caenorhabditis elegans
2019 StandoutNobel
PilZ Domain Proteins Bind Cyclic Diguanylate and Regulate Diverse Processes in Vibrio cholerae
2007
Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa
2012
UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1)
2015 StandoutNobel
Targeting microbial biofilms: current and prospective therapeutic strategies
2017 Standout
Role of the GGDEF protein family in Salmonella cellulose biosynthesis and biofilm formation
2004
Bacterial biofilm and associated infections
2017 Standout
Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci
2007 Standout
The structural basis of cyclic diguanylate signal transduction by PilZ domains
2007
YfiBNR Mediates Cyclic di-GMP Dependent Small Colony Variant Formation and Persistence in Pseudomonas aeruginosa
2010
Genome-wide Transcriptional Profile of Escherichia coli in Response to High Levels of the Second Messenger 3′,5′-Cyclic Diguanylic Acid
2006
Second messenger-mediated spatiotemporal control of protein degradation regulates bacterial cell cycle progression
2009
Regulatory Cohesion of Cell Cycle and Cell Differentiation through Interlinked Phosphorylation and Second Messenger Networks
2011
The potential of 3′,5′-cyclic diguanylic acid (c-di-GMP) as an effective vaccine adjuvant
2010
A chemical proteomics approach to identify c-di-GMP binding proteins in Pseudomonas aeruginosa
2011
A Polymeric Protein Anchors the Chromosomal Origin/ParB Complex at a Bacterial Cell Pole
2008 StandoutNobel
Ginger Extract Inhibits Biofilm Formation by Pseudomonas aeruginosa PA14
2013
The role of PilZ domain proteins in the virulence of Xanthomonas campestris pv. campestris
2008
Biofilms: the matrix revisited
2004 Standout
Identification of a novel regulatory protein (CsrD) that targets the global regulatory RNAs CsrB and CsrC for degradation by RNase E
2006
Allosteric Regulation of Histidine Kinases by Their Cognate Response Regulator Determines Cell Fate
2008
Cellulose nanomaterials review: structure, properties and nanocomposites
2011 Standout
Light‐induced alteration of c‐di‐GMP level controls motility of Synechocystis sp. PCC 6803
2012
Coordinated Cyclic-Di-GMP Repression of Salmonella Motility through YcgR and Cellulose
2012
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity
2015 Standout
Structure of BeF3−-Modified Response Regulator PleD: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition
2007
The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli
2009
Pseudomonas Aeruginosa: Resistance to the Max
2011 Standout
Allosteric Control of Cyclic di-GMP Signaling
2006
Quorum sensing signal–response systems in Gram-negative bacteria
2016 Standout
Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal
2011
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Systematic analysis of cyclic di‐GMP signalling enzymes and their role in biofilm formation and virulence in Yersinia pestis
2010
You’ve come a long way: c-di-GMP signaling
2012
The second messenger bis‐(3′‐5′)‐cyclic‐GMP and its PilZ domain‐containing receptor Alg44 are required for alginate biosynthesis in Pseudomonas aeruginosa
2007
Cyclic di-guanosine-monophosphate comes of age: a novel secondary messenger involved in modulating cell surface structures in bacteria?
2004
Growth of the plant cell wall
2005 Standout
Setting the pace: mechanisms tying Caulobacter cell-cycle progression to macroscopic cellular events
2004
The structure and inhibition of a GGDEF diguanylate cyclase complexed with (c-di-GMP)2at the active site
2011
c-di-GMP Turn-Over in Clostridium difficile Is Controlled by a Plethora of Diguanylate Cyclases and Phosphodiesterases
2011
Bacterial nucleotide-based second messengers
2009
Cellulose Biosynthesis: Current Views and Evolving Concepts
2005
Identification, Activity and Disulfide Connectivity of C-di-GMP Regulating Proteins in Mycobacterium tuberculosis
2010
Comparative genomics of cyclic-di-GMP signalling in bacteria: post-translational regulation and catalytic activity
2010
Genetic analysis of two phosphodiesterases reveals cyclic diguanylate regulation of virulence factors in Dickeya dadantii
2010
Identification and Characterization of a Cyclic di-GMP-specific Phosphodiesterase and Its Allosteric Control by GTP
2005
Genes essential for morphological development and antibiotic production in Streptomyces coelicolor are targets of BldD during vegetative growth
2010
C‐di‐GMP: the dawning of a novel bacterial signalling system
2005
The RNA binding protein CsrA controls cyclic di‐GMP metabolism by directly regulating the expression of GGDEF proteins
2008
Molecular Mechanisms of Two-Component Signal Transduction
2016
A cyclic‐di‐GMP receptor required for bacterial exopolysaccharide production
2007
Cytokinesis Monitoring during Development
2004
A field guide to bacterial swarming motility
2010 Standout
Biofilms: an emergent form of bacterial life
2016 Standout
Structural Analysis of the GGDEF-EAL Domain-Containing c-di-GMP Receptor FimX
2009
Insights into Yersinia pestis biofilm development: topology and co‐interaction of Hms inner membrane proteins involved in exopolysaccharide production
2008
Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control
2012 Standout
The biofilm matrix
2010 Standout
The HD‐GYP domain of RpfG mediates a direct linkage between the Rpf quorum‐sensing pathway and a subset of diguanylate cyclase proteins in the phytopathogen Xanthomonas axonopodis pv citri
2006
Cyclic di-GMP is Essential for the Survival of the Lyme Disease Spirochete in Ticks
2011
Bacterial Birth Scar Proteins Mark Future Flagellum Assembly Site
2006
Cyclic Di-GMP Phosphodiesterases RmdA and RmdB Are Involved in Regulating Colony Morphology and Development in Streptomyces coelicolor
2012
Genomic and Functional Characterization of Enterococcus faecalis Isolates Recovered From the International Space Station and Their Potential for Pathogenicity
2021 StandoutNobel
Aminoglycoside antibiotics induce bacterial biofilm formation
2005 Nature
Proteins with GGDEF and EAL domains regulatePseudomonas putidabiofilm formation and dispersal
2006
An Unorthodox Bacteriophytochrome from Rhodobacter sphaeroides Involved in Turnover of the Second Messenger c-di-GMP
2006
The PilZ Domain Is a Receptor for the Second Messenger c-di-GMP
2006
Body-Centered-Cubic Ni and Its Magnetic Properties
2005
The HD-GYP Domain, Cyclic Di-GMP Signaling, and Bacterial Virulence to Plants
2006
A census of membrane-bound and intracellular signal transduction proteins in bacteria: Bacterial IQ, extroverts and introverts
2005
Cyclic di‐GMP, an established secondary messenger still speeding up
2011
LtmA, a novel cyclic di-GMP-responsive activator, broadly regulates the expression of lipid transport and metabolism genes in Mycobacterium smegmatis
2012
The bacterial second messenger c-di-GMP: mechanisms of signalling
2011
Tyrosine phosphatase TpbA controls rugose colony formation in Pseudomonas aeruginosa by dephosphorylating diguanylate cyclase TpbB
2010
A multi‐repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non‐canonical diguanylate cyclase
2011
Two-Component Signal Transduction Pathways Regulating Growth and Cell Cycle Progression in a Bacterium: A System-Level Analysis
2005
A review of the biomaterials technologies for infection-resistant surfaces
2013 Standout
A c-di-GMP Effector System Controls Cell Adhesion by Inside-Out Signaling and Surface Protein Cleavage
2011
Phosphorylation-Independent Regulation of the Diguanylate Cyclase WspR
2008
Characterization of the rdar morphotype, a multicellular behaviour in Enterobacteriaceae
2005
Nanomaterial-based therapeutics for antibiotic-resistant bacterial infections
2020 Standout
Pseudomonas aeruginosa cupA ‐encoded fimbriae expression is regulated by a GGDEF and EAL domain‐dependent modulation of the intracellular level of cyclic diguanylate
2007
Quantitative determination of cyclic diguanosine monophosphate concentrations in nucleotide extracts of bacteria by matrix-assisted laser desorption/ionization–time-of-flight mass spectrometry
2008
Implant infections: adhesion, biofilm formation and immune evasion
2018 Standout
The phosphodiesterase activity of the HmsP EAL domain is required for negative regulation of biofilm formation inYersinia pestis
2005
Cyclic‐di‐GMP‐mediated signalling within the σS network of Escherichia coli
2006
A liquid chromatography-coupled tandem mass spectrometry method for quantitation of cyclic di-guanosine monophosphate
2010
BcsQ is an essential component of the Escherichia coli cellulose biosynthesis apparatus that localizes at the bacterial cell pole
2009
Activation of the Diguanylate Cyclase PleD by Phosphorylation-mediated Dimerization
2007
Phosphate‐dependent modulation of c‐di‐GMP levels regulates Pseudomonas fluorescens Pf0‐1 biofilm formation by controlling secretion of the adhesin LapA
2006
Proper Scaling of the Anomalous Hall Effect
2009 Standout
The orphan histidine protein kinase SgmT is a c‐di‐GMP receptor and regulates composition of the extracellular matrix together with the orphan DNA binding response regulator DigR in Myxococcus xanthus
2012
The c-di-GMP Binding Protein YcgR Controls Flagellar Motor Direction and Speed to Affect Chemotaxis by a “Backstop Brake” Mechanism
2010
A spindle-like apparatus guides bacterial chromosome segregation
2010 StandoutNobel
Subcellular location characteristics of the Pseudomonas aeruginosa GGDEF protein, WspR, indicate that it produces cyclic‐di‐GMP in response to growth on surfaces
2007
Structural and mechanistic determinants of c-di-GMP signalling
2009
Complex regulatory network encompassing the Csr, c‐di‐GMP and motility systems of Salmonella Typhimurium
2009
Analysis of FimX, a phosphodiesterase that governs twitching motility in Pseudomonas aeruginosa
2006
HD‐GYP domain proteins regulate biofilm formation and virulence in Pseudomonas aeruginosa
2008
A glutamate‐alanine‐leucine (EAL) domain protein of Salmonella controls bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP
2005
Principles of c-di-GMP signalling in bacteria
2009
Allosteric activation of exopolysaccharide synthesis through cyclic di‐GMP‐stimulated protein–protein interaction
2012
Microtiter Dish Biofilm Formation Assay
2011 Standout
Cyclic di-GMP as a second messenger
2006
Monitoring of diguanylate cyclase activity and of cyclic-di-GMP biosynthesis by whole-cell assays suitable for high-throughput screening of biofilm inhibitors
2009
Co‐regulation of Xanthomonas campestris virulence by quorum sensing and a novel two‐component regulatory system RavS/RavR
2009
Crystal Structures of YkuI and Its Complex with Second Messenger Cyclic Di-GMP Suggest Catalytic Mechanism of Phosphodiester Bond Cleavage by EAL Domains
2009
Structural basis of ligand binding by a c-di-GMP riboswitch
2009
The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium
2012 Nature
Structural Insight into the Mechanism of c-di-GMP Hydrolysis by EAL Domain Phosphodiesterases
2010
Multidrug efflux pumps: structure, function and regulation
2018 Standout
Systematic Analysis of Diguanylate Cyclases That Promote Biofilm Formation by Pseudomonas fluorescens Pf0-1
2011
Electronic structure calculations with dynamical mean-field theory
2006 Standout
Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile
2012
BifA, a Cyclic-Di-GMP Phosphodiesterase, Inversely Regulates Biofilm Formation and Swarming Motility byPseudomonas aeruginosaPA14
2007
DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus
2007
The Ubiquitous Protein Domain EAL Is a Cyclic Diguanylate-Specific Phosphodiesterase: Enzymatically Active and Inactive EAL Domains
2005
Control of Formation and Cellular Detachment from Shewanella oneidensis MR-1 Biofilms by Cyclic di-GMP
2006
Role of Cyclic Di-GMP during El Tor Biotype Vibrio cholerae Infection: Characterization of the In Vivo-Induced Cyclic Di-GMP Phosphodiesterase CdpA
2008
c-di-GMP (3′-5′-Cyclic Diguanylic Acid) Inhibits Staphylococcus aureus Cell-Cell Interactions and Biofilm Formation
2005
MucR, a Novel Membrane-Associated Regulator of Alginate Biosynthesis inPseudomonas aeruginosa
2008
The structure–function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain
2007
A Three-Component Regulatory System Regulates Biofilm Maturation and Type III Secretion inPseudomonas aeruginosa
2005
The diguanylate cyclase YddV controls production of the exopolysaccharide poly-N-acetylglucosamine (PNAG) through regulation of the PNAG biosynthetic pgaABCD operon
2010
A Staphylococcal GGDEF Domain Protein Regulates Biofilm Formation Independently of Cyclic Dimeric GMP
2008
Bacterial scaffold directs pole-specific centromere segregation
2014 StandoutNobel
Bacterial Biofilm and its Role in the Pathogenesis of Disease
2020 Standout
Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis
2012
Cellulose Nanofibers Prepared by TEMPO-Mediated Oxidation of Native Cellulose
2007 Standout
FliL is essential for swarming: motor rotation in absence of FliL fractures the flagellar rod in swarmer cells of Salmonella enterica
2008
Identification and Characterization of CdgB, a Diguanylate Cyclase Involved in Developmental Processes in Streptomyces coelicolor
2011
Surface sensing and lateral subcellular localization of WspA , the receptor in a chemosensory‐like system leading to c‐di‐GMP production
2012
Role of EAL-Containing Proteins in Multicellular Behavior ofSalmonella entericaSerovar Typhimurium
2007
Cyclic Dimeric GMP Signaling Regulates Intracellular Aggregation, Sessility, and Growth of Ehrlichia chaffeensis
2011
Hierarchical involvement of various GGDEF domain proteins in rdar morphotype development of Salmonella enterica serovar Typhimurium
2006
Biofilm Formation Mechanisms and Targets for Developing Antibiofilm Agents
2015
Allosteric Control of Cyclic di-GMP Signaling
2006
Minor Pilins of the Type IV Pilus System Participate in the Negative Regulation of Swarming Motility
2012
Strategies for combating bacterial biofilms: A focus on anti-biofilm agents and their mechanisms of action
2017 Standout
GGDEF and EAL domains inversely regulate cyclic di‐GMP levels and transition from sessility to motility
2004
Structural basis of activity and allosteric control of diguanylate cyclase
2004
Quantification of high-specificity cyclic diguanylate signaling
2012
Cyclic Diguanylate Is a Ubiquitous Signaling Molecule in Bacteria: Insights into Biochemistry of the GGDEF Protein Domain
2005
Cyclic di-GMP Signaling Regulates Invasion by Ehrlichia chaffeensis of Human Monocytes
2010
The Phosphodiesterase DipA (PA5017) Is Essential for Pseudomonas aeruginosa Biofilm Dispersion
2012
SadC Reciprocally Influences Biofilm Formation and Swarming Motility via Modulation of Exopolysaccharide Production and Flagellar Function
2007
Cyclic‐diGMP signal transduction systems in Vibrio cholerae: modulation of rugosity and biofilm formation
2006
Genetic reductionist approach for dissecting individual roles of GGDEF proteins within the c-di-GMP signaling network in Salmonella
2009
Cyclic-di-GMP Regulates Extracellular Polysaccharide Production, Biofilm Formation, and Rugose Colony Development by Vibrio vulnificus
2008
Mechanisms of Cyclic-di-GMP Signaling in Bacteria
2006
Modulation of Pseudomonas aeruginosa Biofilm Dispersal by a Cyclic-Di-GMP Phosphodiesterase with a Putative Hypoxia-Sensing Domain
2010
Adaptive Divergence in Experimental Populations ofPseudomonas fluorescens. II. Role of the GGDEF Regulator WspR in Evolution and Development of the Wrinkly Spreader Phenotype
2006
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus
2011 StandoutNobel
Escherichia coli K-12 YfgF is an anaerobic cyclic di-GMP phosphodiesterase with roles in cell surface remodelling and the oxidative stress response
2010
WIEN2k: An APW+lo program for calculating the properties of solids
2020 Standout
Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger
2013 Standout
The Anaplasma phagocytophilum PleC Histidine Kinase and PleD Diguanylate Cyclase Two-Component System and Role of Cyclic Di-GMP in Host Cell Infection
2008
Electronic structure calculations using dynamical mean field theory
2007
Small-Molecule Labeling of Live Cell Surfaces for Three-Dimensional Super-Resolution Microscopy
2014 StandoutNobel
Maximally localized Wannier functions: Theory and applications
2012 Standout
Living in two Worlds: The Plant and Insect Lifestyles ofXylella fastidiosa
2008 Standout
Signals, Regulatory Networks, and Materials That Build and Break Bacterial Biofilms
2009
Biofilm-Related Infections: Bridging the Gap between Clinical Management and Fundamental Aspects of Recalcitrance toward Antibiotics
2014 Standout
Getting in the Loop: Regulation of Development inCaulobacter crescentus
2010
Drinking water contamination and treatment techniques
2016 Standout
Roles of Cyclic Diguanylate in the Regulation of Bacterial Pathogenesis
2007
Half-metallic ferromagnets: From band structure to many-body effects
2008 Standout
A Role for the EAL-Like Protein STM1344 in Regulation of CsgD Expression and Motility inSalmonella entericaSerovar Typhimurium
2009
Smooth to rugose phase variation in Vibrio cholerae can be mediated by a single nucleotide change that targets c‐di‐GMP signalling pathway
2006
A full-length bifunctional protein involved in c-di-GMP turnover is required for long-term survival under nutrient starvation in Mycobacterium smegmatis
2012
Homogeneous Suspensions of Individualized Microfibrils from TEMPO-Catalyzed Oxidation of Native Cellulose
2006 Standout
The Mononuclear Molybdenum Enzymes
2014 Standout
Cyclic di‐GMP signalling in the virulence and environmental adaptation of Xanthomonas campestris
2006
Structural basis of differential ligand recognition by two classes of bis-(3′-5′)-cyclic dimeric guanosine monophosphate-binding riboswitches
2011
Cyclic Di-GMP Stimulates Biofilm Formation and Inhibits Virulence of Francisella novicida
2012
Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli
2009
The expanding roles of c-di-GMP in the biosynthesis of exopolysaccharides and secondary metabolites
2015
Cyclic di-nucleotide signaling enters the eukaryote domain
2013
Vibrio parahaemolyticusScrC Modulates Cyclic Dimeric GMP Regulation of Gene Expression Relevant to Growth on Surfaces
2007
c-di-GMP Displays A Monovalent Metal Ion-Dependent Polymorphism
2004
Distinct Constrictive Processes, Separated in Time and Space, DivideCaulobacterInner and Outer Membranes
2005 StandoutNobel
The Anabaena sp. Strain PCC 7120 Gene all2874 Encodes a Diguanylate Cyclase and Is Required for Normal Heterocyst Development under High-Light Growth Conditions
2008
Specific Control of Pseudomonas aeruginosa Surface-Associated Behaviors by Two c-di-GMP Diguanylate Cyclases
2010
Prevailing Concepts of c-di-GMP Signaling
2009
PilZ domain is part of the bacterial c-di-GMP binding protein
2005
Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe)
2019 Standout
Structural Classification of Bacterial Response Regulators: Diversity of Output Domains and Domain Combinations
2006
Characterization of starvation‐induced dispersion in Pseudomonas putida biofilms
2005
Get the Message Out: Cyclic-Di-GMP Regulates Multiple Levels of Flagellum-Based Motility
2007
Bacterial Small-Molecule Signaling Pathways
2006 Science
N-Acetylglucosamine-dependent biofilm formation in Pectobacterium atrosepticum is cryptic and activated by elevated c-di-GMP levels
2011
Model of Chronic Equine Endometritis Involving a Pseudomonas aeruginosa Biofilm
2017
Purification and Characterization of a Type III Photolyase from Caulobacter crescentus
2008 StandoutNobel
A CsgD-Independent Pathway for Cellulose Production and Biofilm Formation inEscherichia coli
2006
ScrG, a GGDEF-EAL Protein, Participates in Regulating Swarming and Sticking inVibrio parahaemolyticus
2007
Brucella melitensis Cyclic di-GMP Phosphodiesterase BpdA Controls Expression of Flagellar Genes
2011
Regulation of Vibrio Polysaccharide Synthesis and Virulence Factor Production by CdgC, a GGDEF-EAL Domain Protein, in Vibrio cholerae
2006
Systems Biology of Caulobacter
2007
Works of Stefan Weiser being referenced
Cell cycle-dependent dynamic localization of a bacterial response regulator with a novel di-guanylate cyclase output domain
2004
2002
Atomic correlations in itinerant ferromagnets: Quasi-particle bands of nickel
2003